The imbalance in expression of angiogenic and anti-angiogenic factors as candidate predictive biomarker in preeclampsia

scientific article (publication date: May 2015)

The imbalance in expression of angiogenic and anti-angiogenic factors as candidate predictive biomarker in preeclampsia is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P932PMC publication ID4515231
P698PubMed publication ID26221124

P2093author name stringAzim Nejatizadeh
Kianoosh Malekzadeh
Minoo Rajaei
Pooneh Nikuei
Nasrin Ghasemi
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Evidence supporting a role for blockade of the vascular endothelial growth factor system in the pathophysiology of preeclampsia. Young Investigator AwardQ48348609
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Soluble vascular endothelial growth factor receptor-1 (sFLT-1) mediates downregulation of FLT-1 and prevents activated neutrophils from women with preeclampsia from additional migration by VEGF.Q52936000
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Whole-genome microarray and targeted analysis of angiogenesis-regulating gene expression (ENG, FLT1, VEGF, PlGF) in placentas from pre-eclamptic and small-for-gestational-age pregnanciesQ57248848
Predictive value of angiogenic factors and uterine artery Doppler for early- versus late-onset pre-eclampsia and intrauterine growth restrictionQ57316937
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Preeclampsia up-regulates angiogenesis-associated microRNA (i.e., miR-17, -20a, and -20b) that target ephrin-B2 and EPHB4 in human placentaQ36069875
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A prospective cohort study of the value of maternal plasma concentrations of angiogenic and anti-angiogenic factors in early pregnancy and midtrimester in the identification of patients destined to develop preeclampsiaQ36189562
Circulating angiogenic factors in the pathogenesis and prediction of preeclampsiaQ36288766
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Prediction and prevention of recurrent preeclampsiaQ37231387
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Prenatal Clinical Assessment of sFlt-1 (Soluble fms-like Tyrosine Kinase-1)/PlGF (Placental Growth Factor) Ratio as a Diagnostic Tool for Preeclampsia, Pregnancy-induced Hypertension, and ProteinuriaQ37395519
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The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activationQ39820548
Second-trimester angiogenic factors as biomarkers for future-onset preeclampsiaQ40184951
Influence of hypoxia on vascular endothelial growth factor and chorionic gonadotrophin production in the trophoblast-derived cell lines: JEG, JAr and BeWoQ41101465
Nitric oxide mediates mitogenic effect of VEGF on coronary venular endotheliumQ41250498
Flt-1 but not KDR/Flk-1 tyrosine kinase is a receptor for placenta growth factor, which is related to vascular endothelial growth factor.Q42816830
Cytokine-related genes and oxidation-related genes detected in preeclamptic placentasQ43269905
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.Q43592482
Longitudinal serum concentrations of placental growth factor: evidence for abnormal placental angiogenesis in pathologic pregnanciesQ43991495
Hypoxia-reoxygenation: a potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia.Q44044678
Placental bed biopsies in placental abruptionQ45914319
First trimester urinary placental growth factor and development of pre-eclampsia.Q46120674
Quantitative analysis of trophoblast invasion in preeclampsiaQ46211995
Prediction of preeclampsia with maternal mid-trimester placental growth factor, activin A, fibronectin and uterine artery Doppler velocimetryQ46512653
A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenibQ46757524
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectpre-eclampsiaQ61335
angiogenesis inhibitorQ574834
biomarkerQ864574
P304page(s)251-262
P577publication date2015-05-01
P1433published inIranian journal of reproductive medicine Yazd Research & Clinical Centre for InfertilityQ26842009
P1476titleThe imbalance in expression of angiogenic and anti-angiogenic factors as candidate predictive biomarker in preeclampsia
P478volume13

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cites work (P2860)
Q47836788Cadmium inhibits placental trophoblast cell migration via miRNA regulation of the transforming growth factor beta (TGF-β) pathway.
Q56996369Disruption in the Regulation of Immune Responses in the Placental Subtype of Preeclampsia
Q92909980Evaluation of Placental VEGFA mRNA Expression in Preeclampsia: A Case Control Study
Q47980162Hypoxia downregulates the angiogenesis in human placenta via Notch1 signaling pathway
Q92580237Transcriptome analysis of the effect of pyrroloquinoline quinone disodium (PQQ·Na2) on reproductive performance in sows during gestation and lactation
Q28396485miRNAs as common regulators of the transforming growth factor (TGF)-β pathway in the preeclamptic placenta and cadmium-treated trophoblasts: Links between the environment, the epigenome and preeclampsia

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