| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Bing Yang | Q84080098 |
| P2093 | author name string | Martin H Spalding | |
| Donald P Weeks | |||
| P2860 | cites work | Homologous pairing and strand exchange in genetic recombination | Q22065395 |
| RNA-guided human genome engineering via Cas9 | Q24598394 | ||
| TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain | Q24603277 | ||
| Targeting DNA double-strand breaks with TAL effector nucleases | Q24605087 | ||
| Multiplex genome engineering using CRISPR/Cas systems | Q24609428 | ||
| De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks | Q24624851 | ||
| Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification | Q24651280 | ||
| High-frequency modification of plant genes using engineered zinc-finger nucleases | Q24654686 | ||
| A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity | Q24669850 | ||
| Recommendations from the workshop on Comparative Approaches to Safety Assessment of GM Plant Materials: A road toward harmonized criteria? | Q27311008 | ||
| Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation | Q27681624 | ||
| Development and applications of CRISPR-Cas9 for genome engineering | Q28241526 | ||
| Xanthomonas AvrBs3 family-type III effectors: discovery and function | Q28243062 | ||
| Precise genome modification in the crop species Zea mays using zinc-finger nucleases | Q28243268 | ||
| Genome editing. The new frontier of genome engineering with CRISPR-Cas9 | Q28252298 | ||
| Heritable targeted mutagenesis in maize using a designed endonuclease | Q28260750 | ||
| A simple cipher governs DNA recognition by TAL effectors | Q28265506 | ||
| Breaking the code of DNA binding specificity of TAL-type III effectors | Q28265515 | ||
| T-DNA insertion mutagenesis in Arabidopsis: going back and forth | Q41428468 | ||
| Creation of fragrant rice by targeted knockout of the OsBADH2 gene using TALEN technology | Q41563295 | ||
| Synthetic zinc finger nuclease design and rapid assembly | Q41565877 | ||
| Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9. | Q41873090 | ||
| Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9. | Q42055857 | ||
| Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors. | Q42174678 | ||
| Inhibiting replication of begomoviruses using artificial zinc finger nucleases that target viral-conserved nucleotide motif. | Q42240373 | ||
| DNA replicons for plant genome engineering. | Q42242328 | ||
| CRISPR/Cas9-mediated targeted mutagenesis in the liverwort Marchantia polymorpha L. | Q42242334 | ||
| Rapid and efficient gene modification in rice and Brachypodium using TALENs | Q42390296 | ||
| Application of the CRISPR-Cas system for efficient genome engineering in plants | Q42573785 | ||
| Targeted mutagenesis in rice using CRISPR-Cas system | Q42957706 | ||
| Efficient genome editing in plants using a CRISPR/Cas system. | Q42957714 | ||
| Genome edited sheep and cattle. | Q43076994 | ||
| ZFN-mediated gene targeting of the Arabidopsis protoporphyrinogen oxidase gene through Agrobacterium-mediated floral dip transformation. | Q43080999 | ||
| Genome editing in plants via designed zinc finger nucleases | Q43179154 | ||
| Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells | Q43179664 | ||
| RNA-guided genome editing in plants using a CRISPR-Cas system. | Q43649257 | ||
| Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease | Q43872258 | ||
| High-efficiency TALEN-based gene editing produces disease-resistant rice. | Q43901971 | ||
| CRISPR/Cas9-mediated targeted mutagenesis in Nicotiana tabacum | Q44022346 | ||
| Tailor-made mutations in Arabidopsis using zinc finger nucleases. | Q44438459 | ||
| Targeted mutagenesis of the tomato PROCERA gene using transcription activator-like effector nucleases. | Q44555542 | ||
| The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation | Q45265799 | ||
| RNA-guided transcriptional regulation in planta via synthetic dCas9-based transcription factors. | Q45909715 | ||
| Localized egg-cell expression of effector proteins for targeted modification of the Arabidopsis genome | Q46318854 | ||
| CRISPR, the disruptor | Q46719862 | ||
| Targeted mutagenesis in Zea mays using TALENs and the CRISPR/Cas system | Q46919032 | ||
| Trait stacking via targeted genome editing. | Q47761069 | ||
| Targeted genome modification of crop plants using a CRISPR-Cas system. | Q47822803 | ||
| Comparative assessments of CRISPR-Cas nucleases' cleavage efficiency in planta | Q48809246 | ||
| Nuclear gene targeting in Chlamydomonas using engineered zinc-finger nucleases. | Q50488180 | ||
| Zinc finger nuclease-mediated transgene deletion. | Q50553996 | ||
| TAL effector nucleases induce mutations at a pre-selected location in the genome of primary barley transformants. | Q50977601 | ||
| Expression activation and functional analysis of HLA3, a putative inorganic carbon transporter in Chlamydomonas reinhardtii. | Q51010500 | ||
| The CRISPR/Cas system can be used as nuclease for in planta gene targeting and as paired nickases for directed mutagenesis in Arabidopsis resulting in heritable progeny. | Q51041496 | ||
| Targeted mutagenesis using zinc-finger nucleases in perennial fruit trees. | Q51270120 | ||
| High-frequency homologous recombination in plants mediated by zinc-finger nucleases. | Q51327085 | ||
| CRISPR Primer Designer: Design primers for knockout and chromosome imaging CRISPR-Cas system. | Q51401644 | ||
| Looking forward to genetically edited fruit crops. | Q51800888 | ||
| Genome-wide prediction of highly specific guide RNA spacers for CRISPR-Cas9-mediated genome editing in model plants and major crops. | Q52422933 | ||
| CRISPR-P: a web tool for synthetic single-guide RNA design of CRISPR-system in plants. | Q52422996 | ||
| Efficient gene editing in tomato in the first generation using the clustered regularly interspaced short palindromic repeats/CRISPR-associated9 system. | Q52423157 | ||
| Targeted mutagenesis for functional analysis of gene duplication in legumes. | Q53091929 | ||
| Ligation-independent cloning (LIC) assembly of TALEN genes. | Q53389447 | ||
| Emerging tools for synthetic biology in plants | Q58065268 | ||
| Transcriptional activation ofBrassica napusβ-ketoacyl-ACP synthase II with an engineered zinc finger protein transcription factor | Q59663167 | ||
| The requirement for recombination factors differs considerably between different pathways of homologous double-strand break repair in somatic plant cells | Q61639848 | ||
| Genetic recombination in bacteria | Q66885211 | ||
| One-step gene replacement in yeast by cotransformation | Q70109821 | ||
| US regulation misses some GM crops | Q74202405 | ||
| Tuber-Specific Silencing of the Acid Invertase Gene Substantially Lowers the Acrylamide-Forming Potential of Potato | Q82306664 | ||
| Heritable site-specific mutagenesis using TALENs in maize | Q86644914 | ||
| Mesoporous silica nanoparticle-mediated intracellular cre protein delivery for maize genome editing via loxP site excision | Q87012909 | ||
| Genomic engineering and the future of medicine | Q39035879 | ||
| Male-sterile maize plants produced by targeted mutagenesis of the cytochrome P450-like gene (MS26) using a re-designed I-CreI homing endonuclease | Q39083067 | ||
| Perspectives on transgenic, herbicide-resistant crops in the United States almost 20 years after introduction | Q39155475 | ||
| Targeted molecular trait stacking in cotton through targeted double-strand break induction | Q39400592 | ||
| Transposable elements in prokaryotes | Q40128634 | ||
| Transposable Elements in Yeast | Q40138778 | ||
| Targeted transcriptional repression using a chimeric TALE-SRDX repressor protein. | Q40435603 | ||
| Efficient targeted mutagenesis in potato by the CRISPR/Cas9 system | Q40828728 | ||
| A Robust CRISPR/Cas9 System for Convenient, High-Efficiency Multiplex Genome Editing in Monocot and Dicot Plants | Q41008314 | ||
| Targeted gene mutation in tetraploid potato through transient TALEN expression in protoplasts | Q41106790 | ||
| Gene targeting by the TAL effector PthXo2 reveals cryptic resistance gene for bacterial blight of rice | Q41138930 | ||
| Altering the genome by homologous recombination | Q28270159 | ||
| Genome editing with engineered zinc finger nucleases | Q28290795 | ||
| Dicamba resistance: enlarging and preserving biotechnology-based weed management strategies | Q28303838 | ||
| Targeted transgene integration in plant cells using designed zinc finger nucleases | Q28305200 | ||
| Targeted mutagenesis of duplicated genes in soybean with zinc-finger nucleases | Q28308217 | ||
| Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification | Q29029259 | ||
| Site-directed mutagenesis in Arabidopsis using custom-designed zinc finger nucleases | Q29029547 | ||
| Improving CRISPR-Cas nuclease specificity using truncated guide RNAs | Q29616043 | ||
| Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting | Q29616145 | ||
| Mouse homologues of human hereditary disease. | Q30495383 | ||
| Next biotech plants: new traits, crops, developers and technologies for addressing global challenges | Q30886978 | ||
| Molecular genetics using T-DNA in rice | Q31142410 | ||
| Gene targeting using the Agrobacterium tumefaciens-mediated CRISPR-Cas system in rice | Q33737664 | ||
| Efficient CRISPR/Cas9-mediated gene editing in Arabidopsis thaliana and inheritance of modified genes in the T2 and T3 generations | Q33740247 | ||
| Targeted mutagenesis using zinc-finger nucleases in Arabidopsis | Q33836378 | ||
| Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing | Q33875102 | ||
| High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases | Q33977811 | ||
| Biotechnology. Regulating gene drives | Q34041480 | ||
| Editing plant genomes with CRISPR/Cas9. | Q34042537 | ||
| In vivo genome editing using Staphylococcus aureus Cas9 | Q34043628 | ||
| Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. | Q34043681 | ||
| Genome editing. The mutagenic chain reaction: a method for converting heterozygous to homozygous mutations | Q34043840 | ||
| Some aspects of recombination in eukaryotic organisms | Q34087595 | ||
| Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes | Q34175308 | ||
| Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice | Q34248901 | ||
| Transcription activator-like effector nucleases enable efficient plant genome engineering. | Q34309846 | ||
| Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice | Q34368220 | ||
| Improved soybean oil quality by targeted mutagenesis of the fatty acid desaturase 2 gene family | Q34420996 | ||
| Genome engineering empowers the diatom Phaeodactylum tricornutum for biotechnology. | Q34421774 | ||
| Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. | Q34429769 | ||
| Rational design of a split-Cas9 enzyme complex | Q34464381 | ||
| TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis | Q34465379 | ||
| Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining | Q34468164 | ||
| Photoactivatable CRISPR-Cas9 for optogenetic genome editing | Q34480785 | ||
| Successful transient expression of Cas9 and single guide RNA genes in Chlamydomonas reinhardtii | Q34592650 | ||
| A CRISPR/Cas9 toolkit for multiplex genome editing in plants | Q34676725 | ||
| Positive-negative-selection-mediated gene targeting in rice | Q34816459 | ||
| Multigene knockout utilizing off-target mutations of the CRISPR/Cas9 system in rice | Q34994728 | ||
| Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases. | Q35060760 | ||
| Two novel NAC transcription factors regulate gene expression and flowering time by associating with the histone demethylase JMJ14. | Q35088976 | ||
| Target specificity of the CRISPR-Cas9 system. | Q35114320 | ||
| True-breeding targeted gene knock-out in barley using designer TALE-nuclease in haploid cells. | Q35124390 | ||
| Auxin binding protein 1 (ABP1) is not required for either auxin signaling or Arabidopsis development | Q35128851 | ||
| Hairy root transformation using Agrobacterium rhizogenes as a tool for exploring cell type-specific gene expression and function using tomato as a model. | Q35175171 | ||
| Targeted genome modifications in soybean with CRISPR/Cas9. | Q35194033 | ||
| Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system. | Q35212505 | ||
| Dramatic enhancement of genome editing by CRISPR/Cas9 through improved guide RNA design | Q35342386 | ||
| Efficient design and assembly of custom TALENs using the Golden Gate platform. | Q35435360 | ||
| Enabling plant synthetic biology through genome engineering | Q35511349 | ||
| The structural biology of CRISPR-Cas systems | Q35561686 | ||
| High-throughput functional genomics using CRISPR-Cas9. | Q35597703 | ||
| FLASH assembly of TALENs for high-throughput genome editing | Q36573684 | ||
| Increasing frequencies of site-specific mutagenesis and gene targeting in Arabidopsis by manipulating DNA repair pathways. | Q36660151 | ||
| Targeted mutagenesis of Arabidopsis thaliana using engineered TAL effector nucleases. | Q37213382 | ||
| Targeted deletion and inversion of tandemly arrayed genes in Arabidopsis thaliana using zinc finger nucleases | Q37213384 | ||
| RNA-guided genome editing for target gene mutations in wheat | Q37366548 | ||
| Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis | Q37674388 | ||
| Plant genome engineering with sequence-specific nucleases | Q38085644 | ||
| TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteins | Q38109405 | ||
| From Agrobacterium to viral vectors: genome modification of plant cells by rare cutting restriction enzymes | Q38156091 | ||
| Genome engineering with targetable nucleases | Q38194197 | ||
| TALEN-mediated genome editing: prospects and perspectives | Q38233430 | ||
| Genome editing with engineered nucleases in plants | Q38270435 | ||
| The CRISPR/Cas9 system for plant genome editing and beyond | Q38299114 | ||
| Molecular scissors and their application in genetically modified farm animals | Q38325411 | ||
| DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes | Q38454128 | ||
| Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells. | Q38895804 | ||
| Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells | Q38911544 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 483-495 | |
| P577 | publication date | 2016-02-01 | |
| P1433 | published in | Plant Biotechnology Journal | Q15762398 |
| P1476 | title | Use of designer nucleases for targeted gene and genome editing in plants | |
| P478 | volume | 14 |
| Q64062258 | An EU Perspective on Biosafety Considerations for Plants Developed by Genome Editing and Other New Genetic Modification Techniques (nGMs) |
| Q56996567 | Applications of New Breeding Technologies for Potato Improvement |
| Q40870954 | Biallelic Gene Targeting in Rice. |
| Q55027085 | CRISPR/Cas9-mediated gene targeting in Arabidopsis using sequential transformation. |
| Q39185865 | CRISPR/Cas9-mediated genome editing in plants |
| Q51398305 | Consumer acceptance of food crops developed by genome editing. |
| Q38681556 | Current and future editing reagent delivery systems for plant genome editing |
| Q92239646 | Data Mining by Pluralistic Approach on CRISPR Gene Editing in Plants |
| Q92026093 | Drought Resistance in Rice from Conventional to Molecular Breeding: A Review |
| Q52424738 | Editing Plant Genomes: a new era of crop improvement. |
| Q40266826 | Engineering canker-resistant plants through CRISPR/Cas9-targeted editing of the susceptibility gene CsLOB1 promoter in citrus |
| Q35999633 | Enhanced Rice Blast Resistance by CRISPR/Cas9-Targeted Mutagenesis of the ERF Transcription Factor Gene OsERF922. |
| Q38638723 | Enhancing genetic gain in the era of molecular breeding |
| Q47200774 | Evaluation of the mature grain phytase candidate HvPAPhy_a gene in barley (Hordeum vulgare L.) using CRISPR/Cas9 and TALENs. |
| Q50488507 | Gene replacements and insertions in rice by intron targeting using CRISPR-Cas9. |
| Q26770050 | Gene targeting and transgene stacking using intra genomic homologous recombination in plants |
| Q59143612 | Genome Editing in Plants: An Overview of Tools and Applications |
| Q57073075 | Genome Editing in Rice: Recent Advances, Challenges, and Future Implications |
| Q48125113 | Genome editing of bread wheat using biolistic delivery of CRISPR/Cas9 in vitro transcripts or ribonucleoproteins. |
| Q46638570 | Highly efficient heritable plant genome engineering using Cas9 orthologues from Streptococcus thermophilus and Staphylococcus aureus |
| Q38809716 | Homology-based double-strand break-induced genome engineering in plants |
| Q96303643 | Improvement of the Rice "Easy-to-Shatter" Trait via CRISPR/Cas9-Mediated Mutagenesis of the qSH1 Gene |
| Q38631899 | Improvements in algal lipid production: a systems biology and gene editing approach |
| Q39216496 | New variants of CRISPR RNA-guided genome editing enzymes. |
| Q38850026 | Next stop for the CRISPR revolution: RNA-guided epigenetic regulators |
| Q51731770 | Novel alleles of rice eIF4G generated by CRISPR/Cas9-targeted mutagenesis confer resistance to Rice tungro spherical virus. |
| Q39458398 | Photoreceptor Mediated Plant Growth Responses: Implications for Photoreceptor Engineering toward Improved Performance in Crops. |
| Q91670835 | Plant Genes Benefitting Aphids-Potential for Exploitation in Resistance Breeding |
| Q64252179 | Plant Genome Engineering for Targeted Improvement of Crop Traits |
| Q38773159 | Precise Genome Modification via Sequence-Specific Nucleases-Mediated Gene Targeting for Crop Improvement |
| Q41051871 | Precise insertion and guided editing of higher plant genomes using Cpf1 CRISPR nucleases. |
| Q46434626 | Precise, flexible and affordable gene stacking for crop improvement |
| Q46341569 | Production of low-Cs+ rice plants by inactivation of the K+ transporter OsHAK1 with the CRISPR-Cas system |
| Q38792926 | Progress of targeted genome modification approaches in higher plants |
| Q28079621 | Rapid Evolution of Manifold CRISPR Systems for Plant Genome Editing |
| Q98226441 | Recombinase-mediated integration of a multigene cassette in rice leads to stable expression and inheritance of the stacked locus |
| Q92285533 | Replacement of stacked transgenes in planta |
| Q33586055 | Significant enhancement of fatty acid composition in seeds of the allohexaploid, Camelina sativa, using CRISPR/Cas9 gene editing |
| Q50109226 | TALEN-mediated targeted mutagenesis of more than 100 COMT copies/alleles in highly polyploid sugarcane improves saccharification efficiency without compromising biomass yield. |
| Q90705299 | The Role of Noncoding RNAs in Double-Strand Break Repair |
| Q30491879 | The Sequences of 1,504 Mutants in the Model Rice Variety Kitaake Facilitate Rapid Functional Genomic Studies |
| Q38823331 | The expanding footprint of CRISPR/Cas9 in the plant sciences |
| Q47196700 | Translational genomics of grain size regulation in wheat |
| Q46622731 | Using CRISPR/Cas in three dimensions: towards synthetic plant genomes, transcriptomes and epigenomes |
| Q64388969 | Zinc finger nuclease-mediated targeting of multiple transgenes to an endogenous soybean genomic locus via non-homologous end joining |
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