| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Lan Tan | Q66911182 |
| Jin-Tai Yu | Q37837814 | ||
| P2093 | author name string | Hao Wang | |
| Meng-Shan Tan | |||
| Rui-Chun Lu | |||
| P2860 | cites work | Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms | Q21266601 |
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| AD and cancer: epidemiology makes for strange bedfellows. | Q53453396 | ||
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| The fundamental role of epigenetic events in cancer | Q56421597 | ||
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| p53 protein accumulation detected by five different antibodies: relationship to prognosis and heat shock protein 70 in breast cancer | Q72065192 | ||
| Clinical significance of heat shock protein-70 expression in bladder cancer | Q73133433 | ||
| Overexpression of the heat shock protein HSP70 family and p53 protein and prognosis for patients with gastric cancer | Q73516582 | ||
| Genetic variation in the tumor necrosis factor-alpha promoter region and in the stress protein hsp70-2: susceptibility and prognostic implications in breast carcinoma | Q73592380 | ||
| Expression of heat shock protein 72 in renal cell carcinoma: possible role and prognostic implications in cancer patients | Q73685077 | ||
| Expression of heat shock proteins in squamous cell carcinoma of the tongue: an immunohistochemical study | Q74185738 | ||
| Autoantibodies to the 90kDa heat shock protein and poor survival in breast cancer patients | Q77495235 | ||
| Significant correlation between expression of heat shock proteins 27, 70 and lymphocyte infiltration in esophageal squamous cell carcinoma | Q77648006 | ||
| Immunohistochemical detection of pS2 protein and heat shock protein-70 in pancreatic adenocarcinomas. Relationship with disease extent and patient survival | Q77865904 | ||
| Hsp90-Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis | Q81554305 | ||
| Prognostic significance of heat shock proteins HSP70 and HSP90 in endometrial carcinomas. | Q50856443 | ||
| Expression of heat shock proteins HSP70 and HSP90 in endometrial carcinomas. Correlation with clinicopathology, sex steroid receptor status, and p53 protein expression. | Q51033804 | ||
| Insights into the conformational dynamics of the E3 ubiquitin ligase CHIP in complex with chaperones and E2 enzymes. | Q51560326 | ||
| Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex | Q24296990 | ||
| A hitchhiker's guide to the human Hsp70 family | Q24597572 | ||
| Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory | Q24645499 | ||
| Guidelines for the nomenclature of the human heat shock proteins | Q24653946 | ||
| Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1 | Q24685095 | ||
| Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes | Q27650632 | ||
| Worms gang up on bacteria | Q27860588 | ||
| Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1 | Q28118304 | ||
| Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor | Q28142019 | ||
| Heat shock factor 1 represses transcription of the IL-1beta gene through physical interaction with the nuclear factor of interleukin 6 | Q28215984 | ||
| Heat shock proteins and protection of the nervous system | Q28237891 | ||
| Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness | Q28261997 | ||
| Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update | Q28272905 | ||
| Targeting the dynamic HSP90 complex in cancer | Q28288602 | ||
| Hsp90 as a capacitor for morphological evolution | Q28290854 | ||
| Clinical and biological significance of HSP89 alpha in human breast cancer | Q28292734 | ||
| Targeting heat shock proteins in cancer | Q28298397 | ||
| Alzheimer's disease: the amyloid cascade hypothesis | Q29547160 | ||
| Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction | Q29547778 | ||
| HSP90 at the hub of protein homeostasis: emerging mechanistic insights | Q29616824 | ||
| HSP90 and the chaperoning of cancer | Q29617504 | ||
| Hsp90 as a capacitor of phenotypic variation | Q29618584 | ||
| Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport. | Q30519474 | ||
| A DNA sequence directed mutual transcription regulation of HSF1 and NFIX involves novel heat sensitive protein interactions | Q33425228 | ||
| Cancer and neurodegeneration: between the devil and the deep blue sea. | Q33784620 | ||
| Structure and in vivo function of Hsp90. | Q33840745 | ||
| Hsc70 rapidly engages tau after microtubule destabilization | Q33883285 | ||
| Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications | Q33899708 | ||
| Long-term prognostic significance of HSP-70, c-myc and HLA-DR expression in patients with malignant melanoma | Q33936788 | ||
| Heat shock protein 90 in neurodegenerative diseases | Q33961301 | ||
| New tricks for an old dog: the evolving world of Hsp70. | Q34004287 | ||
| Targeting mitochondria for cancer therapy | Q34115304 | ||
| Structure, function, and mechanism of the Hsp90 molecular chaperone | Q34116190 | ||
| Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs | Q34124337 | ||
| Reimagining Alzheimer's disease--an age-based hypothesis | Q34155080 | ||
| CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism. | Q40167651 | ||
| Benzoquinone ansamycin heat shock protein 90 inhibitors modulate multiple functions required for tumor angiogenesis | Q40302671 | ||
| Hsp70 ATPase Modulators as Therapeutics for Alzheimer's and other Neurodegenerative Diseases | Q40848016 | ||
| Dynamic activation of endothelial nitric oxide synthase by Hsp90. | Q41044129 | ||
| Heat shock protein hsp70 in patients with axillary lymph node-negative breast cancer: prognostic implications | Q41082338 | ||
| CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein | Q41776375 | ||
| Prognostic significance of heat shock proteins 27 and 70 in patients with squamous cell carcinoma of the esophagus | Q42471435 | ||
| Chemical manipulation of hsp70 ATPase activity regulates tau stability. | Q42630080 | ||
| Heat shock protein 70 participates in the neuroprotective response to intracellularly expressed beta-amyloid in neurons. | Q43621866 | ||
| Heat-shock protein 70 as a prognostic marker in node-negative breast cancer. | Q44486941 | ||
| Expression of heat shock protein 70 in grossly resected esophageal squamous cell carcinoma | Q44639125 | ||
| Liposomal Hsp90 cDNA induces neovascularization via nitric oxide in chronic ischemia. | Q45233767 | ||
| Exogenous delivery of heat shock protein 70 increases lifespan in a mouse model of amyotrophic lateral sclerosis. | Q46876544 | ||
| HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites | Q46933220 | ||
| Therapeutic effect of exogenous hsp70 in mouse models of Alzheimer's disease | Q47680614 | ||
| Expression of p53, bcl-2 and heat shock protein (hsp72) in malignant and benign ovarian tumours. | Q47716223 | ||
| Molecular oncogene markers and their significance in cutaneous malignant melanoma | Q48024886 | ||
| Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation | Q48315699 | ||
| Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins | Q48648401 | ||
| Nitric oxide and angiogenesis | Q34178838 | ||
| Structure and functional relationships of Hsp90. | Q34267897 | ||
| Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90 | Q34487157 | ||
| Heat shock proteins in cancer: chaperones of tumorigenesis | Q34495261 | ||
| Alzheimer beta-amyloid peptides: normal and abnormal localization | Q34507597 | ||
| Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties | Q34581749 | ||
| Heat shock proteins in the genitourinary system | Q35049582 | ||
| CHIP: a quality-control E3 ligase collaborating with molecular chaperones | Q35097617 | ||
| Heat shock protein 90. | Q35587293 | ||
| The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins | Q35629026 | ||
| Under cover: causes, effects and implications of Hsp90-mediated genetic capacitance | Q35731039 | ||
| CHIP: a link between the chaperone and proteasome systems | Q35759085 | ||
| Modulation of neurodegeneration by molecular chaperones | Q35990274 | ||
| Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1 | Q36194366 | ||
| The role of heat shock proteins Hsp70 and Hsp27 in cellular protection of the central nervous system. | Q36209996 | ||
| Modulation of Hsp90 function in neurodegenerative disorders: a molecular-targeted therapy against disease-causing protein | Q36495265 | ||
| Hsp70 chaperone as a survival factor in cell pathology | Q36674471 | ||
| Activation of Drosophila heat shock factor: conformational change associated with a monomer-to-trimer transition | Q36686240 | ||
| The inverse association of cancer and Alzheimer's: a bioenergetic mechanism | Q36767917 | ||
| Extracellular heat shock proteins in cell signaling | Q36820748 | ||
| Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells. | Q37033622 | ||
| Induction of angiogenesis by heat shock protein 90 mediated by protein kinase Akt and endothelial nitric oxide synthase | Q37079164 | ||
| Targeting the oncogene and kinome chaperone CDC37. | Q37177064 | ||
| Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease | Q37336253 | ||
| Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease | Q37807753 | ||
| Tau oligomers and tau toxicity in neurodegenerative disease | Q38027936 | ||
| Hsp90 modulation for the treatment of Alzheimer's disease | Q38030122 | ||
| Alzheimer’s disease, cerebrovascular disease, and the β-amyloid cascade. | Q38066233 | ||
| The heat shock response | Q38152771 | ||
| Inverse occurrence of cancer and Alzheimer disease: a population-based incidence study | Q38425488 | ||
| Heat shock protein expression independently predicts clinical outcome in prostate cancer | Q38462724 | ||
| Heat shock protein and p53 expression in head and neck squamous cell carcinoma | Q38472048 | ||
| Hsp27 modulates p53 signaling and suppresses cellular senescence | Q40033614 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Alzheimer's disease | Q11081 |
| HSP70 heat-shock proteins | Q419102 | ||
| neoplasm | Q1216998 | ||
| P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
| P304 | page(s) | 239164 | |
| P577 | publication date | 2014-01-01 | |
| 2014-07-24 | |||
| P1433 | published in | BioMed Research International | Q17509958 |
| P1476 | title | Heat shock proteins at the crossroads between cancer and Alzheimer's disease | |
| P478 | volume | 2014 |
| Q92733875 | Design of Disruptors of the Hsp90-Cdc37 Interface |
| Q27333755 | Dihydropyridine Derivatives Modulate Heat Shock Responses and have a Neuroprotective Effect in a Transgenic Mouse Model of Alzheimer's Disease |
| Q55420649 | Dihydropyridines Allosterically Modulate Hsp90 Providing a Novel Mechanism for Heat Shock Protein Co-induction and Neuroprotection. |
| Q39242393 | Heat shock proteins and kidney disease: perspectives of HSP therapy |
| Q64087496 | Modulation of Disordered Proteins with a Focus on Neurodegenerative Diseases and Other Pathologies |
| Q91687496 | Taking Advantage of the Selectivity of Histone Deacetylases and Phosphodiesterase Inhibitors to Design Better Therapeutic Strategies to Treat Alzheimer's Disease |
| Q36369556 | Targeting the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation |
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