Hsp90 as a capacitor for morphological evolution (scientific article)

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Q47259561	Gene expression regulation by heat-shock proteins: the cardinal roles of HSF1 and Hsp90.
Q40126638	Gene expression stasis and plasticity following migration into a foreign environment.
Q51983943	Gene network polymorphism is the raw material of natural selection: the selfish gene network hypothesis.
Q34649576	Generators of phenotypic diversity in the evolution of pathogenic microorganisms
Q21091148	Genes confer similar robustness to environmental, stochastic, and genetic perturbations in yeast
Q35574849	Genetic Architecture of Micro-Environmental Plasticity in Drosophila melanogaster
Q35078594	Genetic analysis of speciation by means of introgression into Drosophila melanogaster
Q24548039	Genetic analysis of viable Hsp90 alleles reveals a critical role in Drosophila spermatogenesis
Q27345471	Genetic and Environmental Control of Neurodevelopmental Robustness in Drosophila
Q28681527	Genetic and environmental factors affecting cryptic variations in gene regulatory networks
Q30992984	Genetic assimilation: a review of its potential proximate causes and evolutionary consequences
Q42031257	Genetic basis of adaptive evolution of a polyphenism by genetic accommodation
Q99411829	Genetic buffering and potentiation in metabolism
Q35845515	Genetic code evolution reveals the neutral emergence of mutational robustness, and information as an evolutionary constraint
Q34698874	Genetic constraints on protein evolution
Q34489534	Genetic defects in N-glycosylation and cellular diversity in mammals
Q44497610	Genetic dissection of p23, an Hsp90 cochaperone, reveals a distinct surface involved in estrogen receptor signaling
Q28731289	Genetic divergence between freshwater and marine morphs of alewife (Alosa pseudoharengus): a 'next-generation' sequencing analysis
Q40301483	Genetic instability and divergence of clonal populations in colon cancer cells in vitro.
Q22122022	Genetic predisposition to cancer — insights from population genetics
Q34610326	Genetic screens for factors involved in the notum bristle loss of interspecific hybrids between Drosophila melanogaster and D. simulans
Q38104420	Genetic susceptibility and mechanisms for refractive error
Q34614118	Genetic variation for phenotypically invariant traits detected in teosinte: implications for the evolution of novel forms.
Q34331502	Genetic variation in cancer predisposition: mutational decay of a robust genetic control network
Q47288161	Genetic variation in variability: Phenotypic variability of fledging weight and its evolution in a songbird population.
Q33379081	Genetical genomics: spotlight on QTL hotspots
Q35157836	Genetically determined phenotype covariation networks control bone strength
Q34192551	Genetics and the making of Homo sapiens
Q38747548	Genetics of Genome-Wide Recombination Rate Evolution in Mice from an Isolated Island
Q28394588	Genetics of healthy aging and longevity
Q35963002	Genetics of microenvironmental canalization in Arabidopsis thaliana
Q39726084	Genome sequence of Saccharomyces carlsbergensis, the world's first pure culture lager yeast.
Q34845890	Genome-scale co-evolutionary inference identifies functions and clients of bacterial Hsp90
Q34894739	Genome-wide analysis of the Populus Hsp90 gene family reveals differential expression patterns, localization, and heat stress responses
Q51753273	Genome-wide high-frequency non-Mendelian loss of heterozygosity in rice.
Q34405735	Genome-wide non-mendelian inheritance of extra-genomic information in Arabidopsis
Q50085780	Genomic buffering mitigates the effects of deleterious mutations in bacteria.
Q64963172	Genomic clustering of fitness-affecting mutations favors the evolution of chromosomal instability.
Q37117012	Genomic consequences of background effects on scalloped mutant expressivity in the wing of Drosophila melanogaster
Q101051150	Genotype by environment interaction for gene expression in Drosophila melanogaster
Q38077445	Genotype to phenotype: lessons from model organisms for human genetics
Q52099216	Genotype-specific responses of fluctuating asymmetry and of preadult survival to the effects of lead and temperature stress in Drosophila melanogaster
Q34153590	Glycoprotein folding in the endoplasmic reticulum
Q38764474	Goldfish morphology as a model for evolutionary developmental biology.
Q41990114	Group II archaeal chaperonin recognition of partially folded human γD-crystallin mutants
Q42480755	HEAT SHOCK PROTEIN 90C is a bona fide Hsp90 that interacts with plastidic HSP70B in Chlamydomonas reinhardtii
Q42380877	HSP90 Inhibition and Cellular Stress Elicits Phenotypic Plasticity in Hematopoietic Differentiation
Q92519795	HSP90 Molecular Chaperones, Metabolic Rewiring, and Epigenetics: Impact on Tumor Progression and Perspective for Anticancer Therapy
Q38953212	HSP90 Shapes the Consequences of Human Genetic Variation
Q36183675	HSP90 Stabilizes Auxin-Responsive Phenotypes by Masking a Mutation in the Auxin Receptor TIR1.
Q36498432	HSP90 affects the expression of genetic variation and developmental stability in quantitative traits
Q29617504	HSP90 and the chaperoning of cancer
Q34482045	HSP90 as a new therapeutic target for cancer therapy: the story unfolds
Q29616824	HSP90 at the hub of protein homeostasis: emerging mechanistic insights
Q50517360	HSP90 canonical content organizes a molecular scaffold mechanism to progress flowering.
Q34793260	HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models
Q36377911	HSP90 stabilizes auxin receptor TIR1 and ensures plasticity of auxin responses
Q47734561	HSP90, a capacitor of behavioral variation
Q36498436	HSP90-buffered genetic variation is common in Arabidopsis thaliana
Q38584468	HSP90AB1: Helping the good and the bad.
Q34510091	HSP90α plays an important role in piRNA biogenesis and retrotransposon repression in mouse
Q36279553	Hallmarks of therapeutic management of the cystic fibrosis functional landscape.
Q26774064	Hazards inherent in interdisciplinary behavioral research
Q40925552	Heat Shock Protein 90 regulates encystation in Entamoeba
Q90080306	Heat Shock Proteins Are Essential Components in Transformation and Tumor Progression: Cancer Cell Intrinsic Pathways and Beyond
Q37013952	Heat Shock Proteins Promote Cancer: It's a Protection Racket
Q48331448	Heat shock and developmental expression of hsp83 in the filarial nematode Brugia pahangi
Q36834709	Heat shock genes - integrating cell survival and death
Q37547517	Heat shock protein 83 plays pleiotropic roles in embryogenesis, longevity, and fecundity of the pea aphid Acyrthosiphon pisum
Q34351999	Heat shock protein 90 as a drug target against protozoan infections: biochemical characterization of HSP90 from Plasmodium falciparum and Trypanosoma evansi and evaluation of its inhibitor as a candidate drug
Q38357729	Heat shock protein 90 function is essential for Plasmodium falciparum growth in human erythrocytes.
Q39230727	Heat shock protein 90 homeostasis controls stage differentiation in Leishmania donovani
Q38971900	Heat shock protein 90 maintains the stability and function of transcription factor Broad Z7 by interacting with its Broad-Complex-Tramtrack-Bric-a-brac domain.
Q36362840	Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide
Q52708029	Heat shock protein 90: a capacitor or a mutator?
Q36834685	Heat shock protein 90: the cancer chaperone
Q35038788	Heat shock protein and proteasome targeting agents
Q35916107	Heat shock protein-90 dampens and directs signaling stimulated by insulin-like growth factor-1 and insulin
Q21195216	Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation
Q37777181	Heat shock proteins (chaperones) in fish and shellfish and their potential role in relation to fish health: a review
Q34479725	Heat shock proteins and Drosophila aging
Q50567847	Heat shock proteins and cancer: intracellular chaperones or extracellular signalling ligands?
Q28272905	Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update
Q26864311	Heat shock proteins at the crossroads between cancer and Alzheimer's disease
Q64264862	Heat shock proteins create a signature to predict the clinical outcome in breast cancer
Q35070272	Heat shock proteins in breast cancer progression--a suitable case for treatment?
Q35210928	Heat shock proteins in relation to heat stress tolerance of creeping bentgrass at different N levels
Q38737242	Heat-Shock Protein 90-Targeted Nano Anticancer Therapy
Q33259824	Heat-shock promoters: targets for evolution by P transposable elements in Drosophila
Q36066038	Heat-shock protein 90 inhibitors as novel cancer chemotherapeutics - an update
Q36004744	Heat-shock treatment-mediated increase in transduction by recombinant adeno-associated virus 2 vectors is independent of the cellular heat-shock protein 90
Q28510837	Hectd1 is required for development of the junctional zone of the placenta
Q92471557	Heterogeneity of primordial germ cells
Q60054363	Heterologous Hsp90 promotes phenotypic diversity through network evolution
Q50656194	Hidden genetic variation evolves with ecological specialization: the genetic basis of phenotypic plasticity in Arctic charr ecomorphs.
Q51406685	High temperatures reveal cryptic genetic variation in a polymorphic female sperm storage organ.
Q96609310	Highly parallel lab evolution reveals that epistasis can curb the evolution of antibiotic resistance
Q31130020	Histone variant HTZ1 shows extensive epistasis with, but does not increase robustness to, new mutations
Q33861840	Hormesis: an adaptive expectation with emphasis on ionizing radiation
Q36780484	Hormetic modulation of aging and longevity by mild heat stress
Q41671786	Host proteostasis modulates influenza evolution.
Q42940088	How do eubacterial organisms manage aggregation-prone proteome?
Q38982331	How plasticity, genetic assimilation and cryptic genetic variation may contribute to adaptive radiations.
Q55191686	Hsf1 Phosphorylation Generates Cell-to-Cell Variation in Hsp90 Levels and Promotes Phenotypic Plasticity.
Q73500917	Hsp70 (DnaK)--an evolution facilitator?
Q58477233	Hsp70 and Hsp90 change their expression and subcellular localization after microspore embryogenesis induction in Brassica napus L
Q39956857	Hsp70 and thermal pretreatment mitigate developmental damage caused by mitotic poisons in Drosophila
Q24644472	Hsp70 chaperones: cellular functions and molecular mechanism
Q84551753	Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions
Q33632917	Hsp90 & Co. - a holding for folding
Q59792755	Hsp90 Stabilizes SIRT1 Orthologs in Mammalian Cells and
Q37214963	Hsp90 affecting chromatin remodeling might explain transgenerational epigenetic inheritance in Drosophila
Q33607477	Hsp90 and co-chaperones twist the functions of diverse client proteins
Q36088933	Hsp90 and environmental impacts on epigenetic states: a model for the trans-generational effects of diethylstibesterol on uterine development and cancer
Q34157465	Hsp90 and environmental stress transform the adaptive value of natural genetic variation
Q29618584	Hsp90 as a capacitor of phenotypic variation
Q36635195	Hsp90 as a target for drug development
Q36581399	Hsp90 at the crossroads of genetics and epigenetics
Q34173907	Hsp90 depletion goes wild
Q35823157	Hsp90 inhibitors and drug resistance in cancer: the potential benefits of combination therapies of Hsp90 inhibitors and other anti-cancer drugs
Q37277287	Hsp90 inhibitors and the reduction of anti-cancer drug resistance by non-genetic and genetic mechanisms
Q34583912	Hsp90 inhibitors as novel cancer chemotherapeutic agents
Q34173374	Hsp90 is important for fecundity, longevity, and buffering of cryptic deleterious variation in wild fly populations.
Q34427556	Hsp90 modulates CAG repeat instability in human cells
Q92501257	Hsp90 of E. coli modulates assembly of FtsZ, the bacterial tubulin homolog
Q28475988	Hsp90 orchestrates stress response signaling governing fungal drug resistance
Q41995021	Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling
Q34539771	Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast
Q28204780	Hsp90 phosphorylation is linked to its chaperoning function. Assembly of the reovirus cell attachment protein
Q28284142	Hsp90 phosphorylation, Wee1 and the cell cycle
Q28269868	Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons
Q34740694	Hsp90 promotes kinase evolution
Q43141228	Hsp90 reaches new heights. Conference on the Hsp90 chaperone machine
Q27314993	Hsp90 selectively modulates phenotype in vertebrate development
Q53820041	Hsp90 shapes protein and RNA evolution to balance trade-offs between protein stability and aggregation.
Q33659713	Hsp90's secrets unfold: new insights from structural and functional studies
Q36934856	Hsp90--from signal transduction to cell transformation.
Q28243562	Hsp90: a chaperone for HIV-1
Q34473659	Hsp90: a chaperone for protein folding and gene regulation
Q24291482	Hsp90: a specialized but essential protein-folding tool
Q34319594	Hsp90: chaperoning signal transduction
Q81093207	Hsp90: from structure to phenotype
Q35913771	Hsp90: the vulnerable chaperone
Q35155106	Human immunodeficiency virus (HIV) type 1 transframe protein can restore activity to a dimerization-deficient HIV protease variant.
Q40704635	Identification of Hsp90 as a stimulatory host factor involved in influenza virus RNA synthesis
Q27940260	Identification of SSF1, CNS1, and HCH1 as multicopy suppressors of a Saccharomyces cerevisiae Hsp90 loss-of-function mutation
Q37152621	Identification of common and unique modifiers of zebrafish midline bifurcation and cyclopia
Q33867547	Identification of conserved residues required for the binding of a tetratricopeptide repeat domain to heat shock protein 90.
Q31036694	Identification of novel in vivo obligate GroEL/ES substrates based on data from a cell-free proteomics approach.
Q63433250	Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors
Q33508608	Identifying protein stabilizing ligands using GroEL.
Q35170976	Impact of a stress-inducible switch to mutagenic repair of DNA breaks on mutation in Escherichia coli
Q27320086	Impact of gut microbiota on the fly's germ line
Q30838235	In silico genetic robustness analysis of microRNA secondary structures: potential evidence of congruent evolution in microRNA
Q26810029	Inbreeding and sex: canalization, plasticity and sexual selection
Q34267911	Inbreeding-stress interactions: evolutionary and conservation consequences
Q52169686	Independence between developmental stability and canalization in the skull of the house mouse.
Q57150594	Induced mutations alter patterns of quantitative variation, phenotypic integration, and plasticity to elevated CO in Arabidopsis thaliana
Q40580807	Induction of Hsp90 protein expression in malignant melanomas and melanoma metastases
Q35458609	Inferring regulatory mechanisms from patterns of evolutionary divergence
Q34686189	Infrared laser-induced gene expression in targeted single cells of Caenorhabditis elegans
Q34372353	Inheritance beyond plain heritability: variance-controlling genes in Arabidopsis thaliana.
Q42458582	Inherited adaptation of genome-rewired cells in response to a challenging environment.
Q37192047	Inherited human sex reversal due to impaired nucleocytoplasmic trafficking of SRY defines a male transcriptional threshold
Q33533806	Insect evolution: Redesigning the fruitfly
Q40443440	Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption
Q51471195	Insulin signalling underlies both plasticity and divergence of a reproductive trait in Drosophila.
Q42928663	Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis
Q37532887	Integration of two ancestral chaperone systems into one: the evolution of eukaryotic molecular chaperones in light of eukaryogenesis
Q33803992	Intracellular proteolysis
Q36155338	Intramolecular phenotypic capacitance in a modular RNA molecule
Q58459479	Investigating Coral Reef Degradation at Alina's Reef in the Florida Keys: Cellular Physiology of White Grunt (Haemulon plumieri) as a Biological Indicator
Q28575256	Involvement of cell surface HSP90 in cell migration reveals a novel role in the developing nervous system
Q81277082	Involvement of the TRAP-1 homologue, Dd-TRAP1, in spore differentiation during Dictyostelium development
Q37710778	Is canalization more than just a beautiful idea?
Q51697895	Is evolvability evolvable?
Q45188577	Isolation and characterization of an immunogenic fragment of heat shock protein 60 from Trichophyton mentagrophytes.
Q57129851	It's not magic - Hsp90 and its effects on genetic and epigenetic variation
Q80400951	Key issues in achieving an integrative perspective on stress
Q40070747	Lack of tailless leads to an increase in expression variability in Drosophila embryos.
Q57578017	Language as ergonomic perfection
Q73713207	Large accumulation of mRNA and DNA point modifications in a plant senescent tissue
Q64227762	Layers of Cryptic Genetic Variation Underlie a Yeast Complex Trait
Q38206169	Left-right asymmetry of the gnathostome skull: its evolutionary, developmental, and functional aspects
Q64056947	Leishmania donovani 90 kD Heat Shock Protein - Impact of Phosphosites on Parasite Fitness, Infectivity and Casein Kinase Affinity
Q34481875	Lessons from model organisms: phenotypic robustness and missing heritability in complex disease
Q47765923	Limb development takes a measured step toward systems analysis
Q48183899	Little effect of HSP90 inhibition on the quantitative wing traits variation in Drosophila melanogaster
Q36904964	Local adaptation and evolutionary potential along a temperature gradient in the fungal pathogen Rhynchosporium commune
Q34310595	Low level genome mistranslations deregulate the transcriptome and translatome and generate proteotoxic stress in yeast.
Q91405200	Lowering the culture temperature corrects collagen abnormalities caused by HSP47 gene knockout
Q30659534	Macroevolution is more than repeated rounds of microevolution
Q33344233	Maize sex determination and abaxial leaf fates are canalized by a factor that maintains repressed epigenetic states
Q35729999	Mammalian mRNA splice-isoform selection is tightly controlled.
Q60461538	Mapping phenotypes: canalization, plasticity and developmental stability
Q28481516	Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry
Q34124519	Maturation of steroid receptors: an example of functional cooperation among molecular chaperones and their associated proteins
Q38718647	Mccrearamycins A-D, Geldanamycin-Derived Cyclopentenone Macrolactams from an Eastern Kentucky Abandoned Coal Mine Microbe.
Q33580440	Measurements of translation initiation from all 64 codons in E. coli
Q55040050	Mechanism of evolution by genetic assimilation : Equivalence and independence of genetic mutation and epigenetic modulation in phenotypic expression.
Q36976462	Mechanisms and evolution of environmental responses in Caenorhabditis elegans
Q26741834	Mechanisms of Hsp90 regulation
Q28082759	Mechanisms of mutational robustness in transcriptional regulation
Q28080783	Mechanistic Asymmetry in Hsp90 Dimers
Q51973924	Mesosternal bristle number in a cosmopolitan drosophilid: an X-linked variable trait independent of sternopleural bristles.
Q52754615	Metabolomic analysis of the selection response of Drosophila melanogaster to environmental stress: are there links to gene expression and phenotypic traits?
Q54137723	MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos.
Q34017534	MicroRNAs and their roles in developmental canalization
Q28252446	Microbial cell individuality and the underlying sources of heterogeneity
Q28681825	Microsatellite-encoded domain in rodent Sry functions as a genetic capacitor to enable the rapid evolution of biological novelty
Q36875674	Mitonuclear Epistasis for Development Time and Its Modification by Diet in Drosophila
Q91577731	Mitonuclear conflict and cooperation govern the integration of genotypes, phenotypes and environments
Q36188406	Modifiers of the Genotype-Phenotype Map: Hsp90 and Beyond
Q33267333	Modularity and intrinsic evolvability of Hsp90-buffered change
Q37903182	Molecular and structural antioxidant defenses against oxidative stress in animals
Q85213922	Molecular biology: Choose your protein partners
Q48222243	Molecular chaperone Hsp90 associates with resistance protein N and its signaling proteins SGT1 and Rar1 to modulate an innate immune response in plants
Q36496399	Molecular chaperones and selection against mutations
Q47785215	Molecular chaperones and the stress of oncogenesis
Q37343873	Molecular chaperones in pathogen virulence: emerging new targets for therapy.
Q29547715	Molecular chaperones in protein folding and proteostasis
Q34165962	Molecular chaperones--cellular machines for protein folding
Q33632311	Molecular chaperones: the busy life of Hsp90.
Q80400955	Molecular chaperones: the modular evolution of cellular networks
Q51357657	Molecular characterization of three Hsp90 from Pieris and expression patterns in response to cold and thermal stress in summer and winter diapause of Pieris melete.
Q24671662	Molecular clock: an anti-neo-Darwinian legacy
Q48068499	Molecular cloning and characterization of four heat shock protein genes from Macrocentrus cingulum (Hymenoptera: Braconidae).
Q50867385	Molecular evolutionary mechanisms driving functional diversification of the HSP90A family of heat shock proteins in eukaryotes.
Q51046987	Molecular genetics: Chaperone protein gets personal.
Q33445336	Molecular identification of differentially regulated genes in the hydrothermal-vent species Bathymodiolus thermophilus and Paralvinella pandorae in response to temperature
Q46269622	Molecular investigation of genetic assimilation during the rapid adaptive radiations of East African cichlid fishes
Q36837925	Molecular mechanisms governing differential robustness of development and environmental responses in plants
Q41932080	Molecular mechanisms of anti-aging hormetic effects of mild heat stress on human cells.
Q40208649	Molecular mechanisms of canalization: Hsp90 and beyond
Q38174591	Molecular mechanisms of paralogous compensation and the robustness of cellular networks
Q26822913	Molecular mechanisms of robustness in plants
Q89486514	Morphological novelty emerges from pre-existing phenotypic plasticity
Q64251984	Mouse Skull Mean Shape and Shape Robustness Rely on Different Genetic Architectures and Different Loci
Q35962309	Multi-locus Genotypes Underlying Temperature Sensitivity in a Mutationally Induced Trait
Q33400248	Multidimensional analysis of Drosophila wing variation in Evolution Canyon
Q26752489	Multifunctional Microtubule-Associated Proteins in Plants
Q39528389	Multiple capacitors for natural genetic variation in Drosophila melanogaster
Q36885382	Mutation rate variation in multicellular eukaryotes: causes and consequences
Q24624037	Mutational robustness can facilitate adaptation
Q24685246	Mutations leading to loss of sporulation ability in Bacillus subtilis are sufficiently frequent to favor genetic canalization
Q34055320	Mutator suppression and escape from replication error-induced extinction in yeast
Q34655913	NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration.
Q36038362	NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.
Q35002352	Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegans model for polyglutamine disease
Q37136710	Natural product inhibitors of Hsp90: potential leads for drug discovery
Q24541501	Near-neutrality in evolution of genes and gene regulation
Q35582253	Near-neutrality, robustness, and epigenetics
Q46812108	Negative Epistasis in Experimental RNA Fitness Landscapes.
Q35844781	Negative feedback confers mutational robustness in yeast transcription factor regulation
Q35144915	Nematode Hsp90: highly conserved but functionally diverse
Q64235552	Network hubs affect evolvability
Q21563565	Network hubs buffer environmental variation in Saccharomyces cerevisiae
Q24615100	Networked buffering: a basic mechanism for distributed robustness in complex adaptive systems
Q36103669	Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells
Q36899148	Neurospora crassa heat shock factor 1 Is an essential gene; a second heat shock factor-like gene, hsf2, is required for asexual spore formation.
Q41888198	New microRNAs in Drosophila--birth, death and cycles of adaptive evolution.
Q27308766	Nitric oxide acts as a positive regulator to induce metamorphosis of the ascidian Herdmania momus
Q59050717	Noise rules
Q28681260	Non-coding RNAs: multi-tasking molecules in the cell
Q28708799	Non-local competition drives both rapid divergence and prolonged stasis in a model of speciation in populations with degenerate resource consumption
Q37117023	Nonadditive expression of homoeologous genes is established upon polyploidization in hexaploid wheat
Q35991123	Nonlinear Dynamics in Gene Regulation Promote Robustness and Evolvability of Gene Expression Levels
Q45360855	Novel arrangement and comparative analysis of hsp90 family genes in three thermotolerant species of Stratiomyidae (Diptera).
Q52836209	Novel genetic capacitors and potentiators for the natural genetic variation of sensory bristles and their trait specificity in Drosophila melanogaster.
Q37813152	Novel therapeutic strategies in multiple myeloma: role of the heat shock protein inhibitors
Q28569589	Odorants as cell-type specific activators of a heat shock response in the rat olfactory mucosa
Q35664375	On the Nature and Evolutionary Impact of Phenotypic Robustness Mechanisms.
Q61449485	On the Reciprocally Causal and Constructive Nature of Developmental Plasticity and Robustness
Q55559653	Oncogenic addiction to high 26S proteasome level.
Q38093796	Opportunities and challenges for molecular chaperone modulation to treat protein-conformational brain diseases
Q34456547	Opposing effects of folding and assembly chaperones on evolvability of Rubisco
Q31924315	Opposite effects of the Hsp90 inhibitor Geldanamycin: induction of apoptosis in PC12, and differentiation in N2A cells
Q73564976	Organization and structure of the Giardia genome
Q38092221	Origin of evolutionary change in avian clutch size
Q53384664	Origin of the neutral and nearly neutral theories of evolution.
Q39478378	Overexpression of AtHsp90.2, AtHsp90.5 and AtHsp90.7 in Arabidopsis thaliana enhances plant sensitivity to salt and drought stresses.
Q48448556	PHOX2B germline and somatic mutations in late-onset central hypoventilation syndrome.
Q34039572	PIWI proteins and PIWI-interacting RNAs in the soma
Q38425435	Parental identity influences progeny responses to incubation thermal stress in sockeye salmon Onchorhynchus nerka
Q29618887	Pathways of chaperone-mediated protein folding in the cytosol
Q34271971	Perspective: Evolution and detection of genetic robustness
Q38549040	Pervasive robustness in biological systems.
Q78732204	Pharmacogenomics in cancer drug discovery and development: inhibitors of the Hsp90 molecular chaperone
Q44202026	Pharmacological prevention of Parkinson disease in Drosophila.
Q34998365	Phenotypic and genetic consequences of protein damage
Q35762881	Phenotypic convergence in bacterial adaptive evolution to ethanol stress
Q28469256	Phenotypic diversity and altered environmental plasticity in Arabidopsis thaliana with reduced Hsp90 levels
Q39393652	Phenotypic diversity, population structure and stress protein-based capacitoring in populations of Xeropicta derbentina, a heat-tolerant land snail species
Q50704325	Phenotypic heterogeneity can enhance rare-cell survival in 'stress-sensitive' yeast populations.
Q37115037	Phenotypic integration of skeletal traits during growth buffers genetic variants affecting the slenderness of femora in inbred mouse strains
Q38177306	Phenotypic plasticity and epigenetic marking: an assessment of evidence for genetic accommodation
Q29614515	Phenotypic plasticity and the epigenetics of human disease
Q33787403	Phenotypic plasticity can facilitate adaptive evolution in gene regulatory circuits
Q33733118	Phenotypic plasticity facilitates recurrent rapid adaptation to introduced predators
Q33274208	Phenotypic plasticity in Drosophila pigmentation caused by temperature sensitivity of a chromatin regulator network
Q33662766	Phenotypic plasticity in the range-margin population of the lycaenid butterfly Zizeeria maha
Q47331678	Phenotypic plasticity of body size in a temperate population of Drosophila melanogaster: when the temperature-size rule does not apply
Q51875929	Phenotypic robustness can increase phenotypic variability after nongenetic perturbations in gene regulatory circuits.
Q44769960	Phylogenetic analysis of eukaryotes using heat-shock protein Hsp90.
Q35435973	Physics and the canalization of morphogenesis: a grand challenge in organismal biology
Q28755485	Physiological Diversity in Insects: Ecological and Evolutionary Contexts
Q30042023	Plasmodium falciparum heat shock protein 110 stabilizes the asparagine repeat-rich parasite proteome during malarial fevers
Q48470373	Plastic flies: the regulation and evolution of trait variability in Drosophila.
Q36834689	Polyglutamine expansion in Drosophila: thermal stress and Hsp70 as selective agents
Q39844194	Population responses to anthropogenic disturbance: lessons from three‐spined sticklebacksGasterosteus aculeatusin eutrophic habitats
Q36875232	Population transcriptomics uncovers the regulation of gene expression variation in adaptation to changing environment
Q50522799	Post-embryonic functions of HSP90 in Tribolium castaneum include the regulation of compound eye development.
Q34606166	Post-transcriptional repair of a split heat shock protein 90 gene by mRNA trans-splicing
Q55513021	Post-translational buffering leads to convergent protein expression levels between primates.
Q34811520	Potential genetic variance and the domestication of maize
Q56927558	Potential role of the heat shock protein 90 (hsp90) in buffering mutations to favour cyclical parthenogenesis in the peach potato aphid Myzus persicae (Aphididae, Hemiptera)
Q36368879	Power provides protection: Genetic robustness in yeast depends on the capacity to generate energy
Q51837124	Predicting mutation outcome from early stochastic variation in genetic interaction partners.
Q21145845	Prion switching in response to environmental stress
Q48425764	Prions and chaperones: Outside the fold.
Q40300772	Profiling of Brevibacillus borstelensis transcriptome exposed to high temperature shock
Q34189462	Progress and potential of Drosophila protein interaction maps
Q51752072	Progress and prospects for targeting Hsp90 to treat fungal infections.
Q34074075	Progress on canalization
Q21560899	Progressive, transgenerational changes in offspring phenotype and epigenotype following nutritional transition
Q73255932	Prokaryote and eukaryote evolvability
Q28189476	Proliferation, cell cycle and apoptosis in cancer
Q34205949	Promoter nucleosome organization shapes the evolution of gene expression
Q34611621	Proposal for a role of the Hsp90/Hsp70-based chaperone machinery in making triage decisions when proteins undergo oxidative and toxic damage
Q26801512	Protein Folding and Mechanisms of Proteostasis
Q34225700	Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution
Q58700273	Protein evolution speed depends on its stability and abundance and on chaperone concentrations
Q33570364	Protein evolution via amino acid and codon elimination
Q35761364	Protein expression parallels thermal tolerance and ecologic changes in the diversification of a diving beetle species complex
Q34152827	Protein folding in the cytoplasm and the heat shock response
Q42724601	Protein folding taking shape. Workshop on molecular chaperones
Q37832796	Protein folding, protein homeostasis, and cancer.
Q36109387	Protein homeostasis in models of aging and age-related conformational disease
Q33728820	Protein misfolding and degradation in genetic diseases.
Q92950813	Protein quality control machinery in intracellular protozoan parasites: hopes and challenges for therapeutic targeting
Q52699324	Proteomic characterization of a temperature-sensitive conditional lethal in Drosophila melanogaster.
Q28286034	Proteomic data from human cell cultures refine mechanisms of chaperone-mediated protein homeostasis
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P6179	Dimensions Publication ID	1032477985
P356	DOI	10.1038/24550
P3181	OpenCitations bibliographic resource ID	326141
P698	PubMed publication ID	9845070
P5875	ResearchGate publication ID	13442806

P2093	author name string	S Lindquist
		S L Rutherford
P2860	cites work	Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila.	Q45975761
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P433	issue	6709
P407	language of work or name	English	Q1860
P921	main subject	capacitor	Q5322
P304	page(s)	336-42
P577	publication date	1998-11-26
P1433	published in	Nature	Q180445
P1476	title	Hsp90 as a capacitor for morphological evolution
P478	volume	396

Hsp90 as a capacitor for morphological evolution

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