scholarly article | Q13442814 |
P819 | ADS bibcode | 2011PLoSO...622579M |
P356 | DOI | 10.1371/JOURNAL.PONE.0022579 |
P932 | PMC publication ID | 3143160 |
P698 | PubMed publication ID | 21799905 |
P5875 | ResearchGate publication ID | 51531309 |
P50 | author | Sanford Bernstein | Q42880156 |
P2093 | author name string | Karen Ocorr | |
Rolf Bodmer | |||
Girish C Melkani | |||
P2860 | cites work | Drawing the tree of eukaryotic life based on the analysis of 2,269 manually annotated myosins from 328 species | Q21092862 |
KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging | Q24681227 | ||
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 | Q25938983 | ||
UNC-45/CRO1/She4p (UCS) protein forms elongated dimer and joins two myosin heads near their actin binding region | Q27666105 | ||
X-ray Crystal Structure of the UCS Domain-Containing UNC-45 Myosin Chaperone from Drosophila melanogaster | Q27667259 | ||
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes | Q27861039 | ||
The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms | Q28203734 | ||
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila | Q28236209 | ||
Hold me tight: Role of the heat shock protein family of chaperones in cardiac disease | Q28296634 | ||
Unc45b forms a cytosolic complex with Hsp90 and targets the unfolded myosin motor domain | Q28588643 | ||
A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy | Q28593682 | ||
The Genetic Basis for Cardiomyopathy | Q29300961 | ||
Mutations of the Drosophila myosin heavy-chain gene: effects on transcription, myosin accumulation, and muscle function | Q30449673 | ||
Drosophila as a model for the identification of genes causing adult human heart disease | Q30476715 | ||
Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles | Q30481206 | ||
A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. | Q30494112 | ||
Morphology of the pupal heart, adult heart, and associated tissues in the fruit fly, Drosophila melanogaster. | Q52570904 | ||
UNC-45 is required for NMY-2 contractile function in early embryonic polarity establishment and germline cellularization in C. elegans. | Q53505697 | ||
Alpha B-crystallin mutation in dilated cardiomyopathy | Q55671182 | ||
Differential Expression of Heat Shock Proteins in Normal and Failing Human Hearts | Q59192159 | ||
Fission yeast Rng3p: an UCS-domain protein that mediates myosin II assembly during cytokinesis | Q73893519 | ||
A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts | Q30494115 | ||
Paralysis and delayed Z-disc formation in the Xenopus tropicalis unc45b mutant dicky ticker | Q30495962 | ||
Signalling pathways involved in adult heart formation revealed by gene expression profiling in Drosophila | Q33302677 | ||
Knockdown and overexpression of Unc-45b result in defective myofibril organization in skeletal muscles of zebrafish embryos. | Q33694916 | ||
Two mammalian UNC-45 isoforms are related to distinct cytoskeletal and muscle-specific functions | Q34152511 | ||
Drosophila UNC-45 accumulates in embryonic blastoderm and in muscles, and is essential for muscle myosin stability | Q34574189 | ||
Sarcomere gene mutations in hypertrophy and heart failure | Q34626686 | ||
Control of cardiac development by an evolutionarily conserved transcriptional network | Q34654786 | ||
UCS proteins: managing the myosin motor | Q35169547 | ||
Genetic approaches to understanding muscle development. | Q35491615 | ||
Genetic control of heart function and aging in Drosophila | Q35945999 | ||
The UNC-45 chaperone mediates sarcomere assembly through myosin degradation in Caenorhabditis elegans | Q36118132 | ||
Unc-45 mutations in Caenorhabditis elegans implicate a CRO1/She4p-like domain in myosin assembly | Q36256331 | ||
UCS protein Rng3p activates actin filament gliding by fission yeast myosin-II. | Q36322706 | ||
Loss of unc45a precipitates arteriovenous shunting in the aortic arches. | Q36791623 | ||
Hereditary myosin myopathies | Q36791853 | ||
Impact of multiple gene mutations in determining the severity of cardiomyopathy and heart failure. | Q37257754 | ||
Build it up-Tear it down: protein quality control in the cardiac sarcomere | Q37313697 | ||
Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hypertrophied, failing ventricular myocardium. | Q37374337 | ||
Fluorescent labeling of Drosophila heart structures | Q38272328 | ||
Semi-automated Optical Heartbeat Analysis of small hearts. | Q39900702 | ||
The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy | Q40157250 | ||
Role of the myosin assembly protein UNC-45 as a molecular chaperone for myosin | Q40754906 | ||
Myosin II folding is mediated by a molecular chaperonin | Q40929937 | ||
Drosophila UNC-45 prevents heat-induced aggregation of skeletal muscle myosin and facilitates refolding of citrate synthase. | Q41200755 | ||
Rng3, a member of the UCS family of myosin co-chaperones, associates with myosin heavy chains cotranslationally | Q41839057 | ||
Structure and function of contractile proteins in human dilated cardiomyopathy | Q42495495 | ||
Myosin assembly, maintenance and degradation in muscle: Role of the chaperone UNC-45 in myosin thick filament dynamics | Q43187716 | ||
Ostia, the inflow tracts of the Drosophila heart, develop from a genetically distinct subset of cardial cells | Q43552390 | ||
Spatiotemporal gene expression targeting with the TARGET and gene-switch systems in Drosophila | Q44768547 | ||
Steroid-dependent modification of Hox function drives myocyte reprogramming in the Drosophila heart | Q46801086 | ||
A role for the COUP-TF-related gene seven-up in the diversification of cardioblast identities in the dorsal vessel of Drosophila | Q47071291 | ||
Hand is a direct target of Tinman and GATA factors during Drosophila cardiogenesis and hematopoiesis | Q47072392 | ||
The UCS factor Steif/Unc-45b interacts with the heat shock protein Hsp90a during myofibrillogenesis | Q47073713 | ||
The myosin co-chaperone UNC-45 is required for skeletal and cardiac muscle function in zebrafish | Q47073763 | ||
Temperature-sensitive mutation affecting myofilament assembly in Caenorhabditis elegans | Q47849134 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Drosophila | Q312154 |
molecular chaperones | Q422496 | ||
P304 | page(s) | e22579 | |
P577 | publication date | 2011-01-01 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model | |
P478 | volume | 6 |
Q92091710 | Bi-allelic mutations in uncoordinated mutant number-45 myosin chaperone B are a cause for congenital myopathy |
Q51765146 | Ceramide-Protein Interactions Modulate Ceramide-Associated Lipotoxic Cardiomyopathy. |
Q52653807 | Chaperone-mediated reversible inhibition of the sarcomeric myosin power stroke. |
Q42770507 | Chaperoning myosin assembly in muscle formation and aging |
Q38498245 | Drosophila as a potential model to ameliorate mutant Huntington-mediated cardiac amyloidosis |
Q49415841 | Drosophila in the Heart of Understanding Cardiac Diseases: Modeling Channelopathies and Cardiomyopathies in the Fruitfly |
Q48056048 | Fission yeast myosin Myo2 is down-regulated in actin affinity by light chain phosphorylation. |
Q34039121 | Functional and genomic analyses of alpha-solenoid proteins |
Q34055646 | Getting folded: chaperone proteins in muscle development, maintenance and disease |
Q27318284 | Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart |
Q47800894 | Lifetime regular exercise affects the incident of different arrhythmias and improves organismal health in aging female Drosophila melanogaster |
Q36344078 | Loss of function of myosin chaperones triggers Hsf1-mediated transcriptional response in skeletal muscle cells |
Q90857341 | Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin |
Q26863588 | Myosin chaperones |
Q36257819 | Still Heart Encodes a Structural HMT, SMYD1b, with Chaperone-Like Function during Fast Muscle Sarcomere Assembly |
Q45223476 | Structural insight into the UNC-45-myosin complex |
Q47722266 | TRiC/CCT chaperonins are essential for maintaining myofibril organization, cardiac physiological rhythm, and lifespan |
Q27675937 | The Myosin Chaperone UNC-45 Is Organized in Tandem Modules to Support Myofilament Formation in C. elegans |
Q34477894 | The UNC-45 myosin chaperone: from worms to flies to vertebrates. |
Q27321388 | The conserved ADAMTS-like protein lonely heart mediates matrix formation and cardiac tissue integrity |
Q30665184 | Time-restricted feeding attenuates age-related cardiac decline in Drosophila |
Q27302780 | UCS protein Rng3p is essential for myosin-II motor activity during cytokinesis in fission yeast |
Q38285301 | UCS proteins: chaperones for myosin and co-chaperones for Hsp90. |
Q48113345 | UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins |
Q47621531 | UNC-45a promotes myosin folding and stress fiber assembly. |
Q99399885 | Under construction: The dynamic assembly, maintenance, and degradation of the cardiac sarcomere |
Q33950581 | Using Caenorhabditis elegans as a model system to study protein homeostasis in a multicellular organism |
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