scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1044882172 |
P356 | DOI | 10.1007/S13311-014-0305-Y |
P932 | PMC publication ID | 4322077 |
P698 | PubMed publication ID | 25256961 |
P5875 | ResearchGate publication ID | 266246367 |
P50 | author | Brian S Tanaka | Q86495711 |
Michael A Rogawski | Q42775980 | ||
Alan Goldin | Q42884134 | ||
Dorota Zolkowska | Q59260951 | ||
P2093 | author name string | Isaac N Pessah | |
Heike Wulff | |||
Brandon M Brown | |||
David Paul Jenkins | |||
Hai M Nguyen | |||
Nichole Coleman | |||
Yi-Je Chen | |||
Zhengyu Cao | |||
P2860 | cites work | Modulators of Small- and Intermediate-Conductance Calcium-Activated Potassium Channels and their Therapeutic Indications | Q22305804 |
Small-conductance, calcium-activated potassium channels from mammalian brain | Q24318679 | ||
A potassium channel mutation in neonatal human epilepsy | Q24320244 | ||
Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models | Q24605644 | ||
TRPA1 mediates formalin-induced pain | Q24681557 | ||
Molecular targets for antiepileptic drug development | Q24683346 | ||
Progress report on new antiepileptic drugs: a summary of the Eleventh Eilat Conference (EILAT XI) | Q26825591 | ||
Control of electrical activity in central neurons by modulating the gating of small conductance Ca2+-activated K+ channels | Q28141257 | ||
Small-conductance Ca2+-activated K+ channels: form and function | Q28248940 | ||
The neuroprotective agent riluzole activates the two P domain K(+) channels TREK-1 and TRAAK | Q28377513 | ||
Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia | Q28586378 | ||
Protein expression of small conductance calcium-activated potassium channels is altered in inferior colliculus neurons of the genetically epilepsy-prone rat | Q30481496 | ||
KCa channels as therapeutic targets in episodic ataxia type-2 | Q30495677 | ||
Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure | Q33379783 | ||
Small conductance Ca2+-activated K+ channel knock-out mice reveal the identity of calcium-dependent afterhyperpolarization currents | Q33701513 | ||
The Ca2+-dependent slow K+ conductance in cultured rat muscle cells: characterization with apamin | Q33928131 | ||
Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation | Q34323789 | ||
Differential action of riluzole on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels | Q34435972 | ||
An apamin-sensitive Ca2+-activated K+ current in hippocampal pyramidal neurons | Q35136462 | ||
Early Changes in Cerebellar Physiology Accompany Motor Dysfunction in the Polyglutamine Disease Spinocerebellar Ataxia Type 3 | Q35205602 | ||
The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions. | Q35824087 | ||
Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia | Q36056879 | ||
Sodium channel mutations in epilepsy and other neurological disorders | Q36216288 | ||
Selective Positive Modulator of Calcium-Activated Potassium Channels Exerts Beneficial Effects in a Mouse Model of Spinocerebellar Ataxia Type 2 | Q36354944 | ||
Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation | Q36486976 | ||
Key factors in the discovery and development of new antiepileptic drugs | Q37665308 | ||
Mechanisms of action of antiseizure drugs | Q38039637 | ||
New therapy options for amyotrophic lateral sclerosis | Q38121637 | ||
Pharmacological characterization of the 6 Hz psychomotor seizure model of partial epilepsy | Q39222620 | ||
N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): a novel, selective KCNQ2/Q3 potassium channel activator. | Q40033485 | ||
Specific enhancement of SK channel activity selectively potentiates the afterhyperpolarizing current I(AHP) and modulates the firing properties of hippocampal pyramidal neurons. | Q40359725 | ||
Pharmacological modulation of SK3 channels. | Q40802806 | ||
Riluzole in cerebellar ataxia: a randomized, double-blind, placebo-controlled pilot trial | Q43138268 | ||
Distinct contributions of small and large conductance Ca2+-activated K+ channels to rat Purkinje neuron function | Q44308519 | ||
SKCa channels mediate the medium but not the slow calcium-activated afterhyperpolarization in cortical neurons. | Q44835120 | ||
Correlation analysis between anticonvulsant ED50 values of antiepileptic drugs in mice and rats and their therapeutic doses and plasma levels | Q45176492 | ||
K(+)-channel openers suppress epileptiform activities induced by 4-aminopyridine in cultured rat hippocampal neurons | Q46201828 | ||
In vivo profile of ICA-27243 [N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a potent and selective KCNQ2/Q3 (Kv7.2/Kv7.3) activator in rodent anticonvulsant models | Q46520469 | ||
Characterization of a novel high-potency positive modulator of Kv7 channels | Q48094129 | ||
Effects of apamin and nicotinic acetylcholine receptor antagonists on inferior collicular seizures | Q48880652 | ||
Network excitability in a model of chronic temporal lobe epilepsy critically depends on SK channel-mediated AHP currents | Q48919779 | ||
2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission--I. Anticonvulsant properties | Q70146796 | ||
Evidence for decreased calcium dependent potassium conductance in hippocampal CA3 neurons of genetically epilepsy-prone rats | Q71457919 | ||
Development of strains of albino mice with predictable susceptibilities to audiogenic seizures | Q73143925 | ||
In vivo characterisation of the small-conductance KCa (SK) channel activator 1-ethyl-2-benzimidazolinone (1-EBIO) as a potential anticonvulsant | Q80152918 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 234-249 | |
P577 | publication date | 2015-01-01 | |
P1433 | published in | Neurotherapeutics | Q15716631 |
P1476 | title | The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant | |
P478 | volume | 12 |
Q91726406 | 3'-O-Methylorobol Inhibits the Voltage-Gated Sodium Channel Nav1.7 with Anti-Itch Efficacy in A Histamine-Dependent Itch Mouse Model |
Q64276032 | BmK AEP, an Anti-Epileptic Peptide Distinctly Affects the Gating of Brain Subtypes of Voltage-Gated Sodium Channels |
Q62065228 | Ca2+/Calmodulin-Gated Small- and Intermediate-Conductance KCa Channels in Cardiovascular Regulation: Targets for Novel Pharmacological Treatments |
Q36633107 | Development of a Rapid Throughput Assay for Identification of hNav1.7 Antagonist Using Unique Efficacious Sodium Channel Agonist, Antillatoxin |
Q49908057 | Effects of Benzothiazolamines on Voltage-Gated Sodium Channels. |
Q91783451 | Fluorine-containing substituents: metabolism of the α,α-difluoroethyl thioether motif |
Q48258152 | Functional identification of activity-regulated, high-affinity glutamine transport in hippocampal neurons inhibited by riluzole |
Q28080655 | Homeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potential |
Q91615941 | Is Targeting of Compensatory Ion Channel Gene Expression a Viable Therapeutic Strategy for Dravet Syndrome? |
Q28391535 | Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents |
Q47587874 | Modulation of SK channels regulates locomotor alternating bursting activity in the functionally-mature spinal cord |
Q35198051 | Rapid throughput analysis demonstrates that chemicals with distinct seizurogenic mechanisms differentially alter Ca2+ dynamics in networks formed by hippocampal neurons in culture |
Q90732378 | The Trials and Tribulations of Structure Assisted Design of KCa Channel Activators |
Search more.