| scholarly article | Q13442814 |
| P50 | author | Xichun Li | Q86926084 |
| P2093 | author name string | Masayuki Inoue | |
| Fan Zhang | |||
| Zhengyu Cao | |||
| Fang Zhao | |||
| Liang Jin | |||
| Boyang Yu | |||
| P2860 | cites work | Antillatoxin is a sodium channel activator that displays unique efficacy in heterologously expressed rNav1.2, rNav1.4 and rNav1.5 α subunits | Q21262973 |
| Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain | Q24562888 | ||
| Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons | Q24632552 | ||
| Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia | Q24675844 | ||
| Developmental neurotoxicity of pyrethroid insecticides: critical review and future research needs | Q24814126 | ||
| The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant | Q27339255 | ||
| Nomenclature of voltage-gated sodium channels | Q28141860 | ||
| Alternative statistical parameter for high-throughput screening assay quality assessment | Q28283010 | ||
| Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels | Q28379121 | ||
| Phenytoin inhibits the persistent sodium current in neocortical neurons by modifying its inactivation properties | Q28485346 | ||
| Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neurons | Q28569751 | ||
| Endogenous expression of the beta1A sodium channel subunit in HEK-293 cells | Q40879597 | ||
| Basis of the antiseizure action of phenytoin | Q41289597 | ||
| Lidocaine block of cardiac sodium channels | Q41556598 | ||
| Diphenytoin, riluzole and lidocaine: three sodium channel blockers, with different mechanisms of action, decrease hippocampal epileptiform activity | Q42273460 | ||
| Slow closed-state inactivation: a novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel. | Q42686664 | ||
| Increase of sodium current after pyrethroid insecticides in mouse neuroblastoma cells | Q44204489 | ||
| In silico docking reveals possible Riluzole binding sites on Nav1.6 sodium channel: implications for amyotrophic lateral sclerosis therapy | Q45735872 | ||
| Carbamazepine inhibition of neuronal Na+ currents: quantitative distinction from phenytoin and possible therapeutic implications | Q48697139 | ||
| Validation of FLIPR membrane potential dye for high throughput screening of potassium channel modulators. | Q53677715 | ||
| Slow binding of phenytoin to inactivated sodium channels in rat hippocampal neurons. | Q54022626 | ||
| Effects of veratridine on sodium currents and fluxes. | Q54137279 | ||
| A critical role for transmembrane segment IVS6 of the sodium channel alpha subunit in fast inactivation | Q72223457 | ||
| A common anticonvulsant binding site for phenytoin, carbamazepine, and lamotrigine in neuronal Na+ channels | Q77388391 | ||
| A pharmacophore derived phenytoin analogue with increased affinity for slow inactivated sodium channels exhibits a desired anticonvulsant profile | Q30441260 | ||
| High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1. | Q30478958 | ||
| Sodium channel inhibitor drug discovery using automated high throughput electrophysiology platforms | Q33400498 | ||
| Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2 | Q33417208 | ||
| Human embryonic kidney (HEK293) cells express endogenous voltage-gated sodium currents and Na v 1.7 sodium channels | Q33625778 | ||
| Antillatoxin and kalkitoxin, ichthyotoxins from the tropical cyanobacterium Lyngbya majuscula, induce distinct temporal patterns of NMDA receptor-mediated neurotoxicity | Q33873690 | ||
| A novel Nav1.7 mutation producing carbamazepine-responsive erythromelalgia | Q33918510 | ||
| Voltage-gated sodium channels as therapeutic targets | Q33925684 | ||
| Antillatoxin is a marine cyanobacterial toxin that potently activates voltage-gated sodium channels | Q33952224 | ||
| Voltage-gated ion channels and gating modifier toxins. | Q34161355 | ||
| Identification of human Ether-à-go-go related gene modulators by three screening platforms in an academic drug-discovery setting. | Q34407398 | ||
| Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons | Q34426737 | ||
| Differential action of riluzole on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels. | Q34435972 | ||
| Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel | Q34461603 | ||
| On the use of neuro-2a neuroblastoma cells versus intact neurons in primary culture for neurotoxicity studies | Q34470161 | ||
| Overview of molecular relationships in the voltage-gated ion channel superfamily. | Q34480285 | ||
| Mechanisms of use-dependent block of sodium channels in excitable membranes by local anesthetics | Q34534868 | ||
| High-throughput fluorescent-based NKCC functional assay in adherent epithelial cells. | Q34626292 | ||
| Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction | Q34684384 | ||
| The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels. | Q34701722 | ||
| High-throughput electrophysiology: an emerging paradigm for ion-channel screening and physiology | Q34763903 | ||
| Integration of virtual and high-throughput screening | Q34988235 | ||
| The twisted side chain of antillatoxin is important for potent toxicity: total synthesis and biological evaluation of antillatoxin and analogues | Q35016849 | ||
| Differential modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by the local anesthetic lidocaine | Q35047167 | ||
| Additivity of pyrethroid actions on sodium influx in cerebrocortical neurons in primary culture | Q35591794 | ||
| Intra- and interfamily phenotypic diversity in pain syndromes associated with a gain-of-function variant of NaV1.7. | Q35642815 | ||
| Properties of human brain sodium channel α-subunits expressed in HEK293 cells and their modulation by carbamazepine, phenytoin and lamotrigine | Q37585424 | ||
| Lidocaine reduces the transition to slow inactivation in Na(v)1.7 voltage-gated sodium channels | Q38649763 | ||
| Influence of lipid-soluble gating modifier toxins on sodium influx in neocortical neurons | Q39964248 | ||
| A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors | Q40028879 | ||
| Cellular HTS assays for pharmacological characterization of Na(V)1.7 modulators | Q40035901 | ||
| Automated ion channel screening: patch clamping made easy | Q40156501 | ||
| The natural scorpion peptide, BmK NT1 activates voltage-gated sodium channels and produces neurotoxicity in primary cultured cerebellar granule cells. | Q40283974 | ||
| Carbamazepine interacts with a slow inactivation state of NaV1.8-like sodium channels | Q40288025 | ||
| Functional assay of voltage-gated sodium channels using membrane potential-sensitive dyes. | Q40529990 | ||
| Overexpression of T-type calcium channels in HEK-293 cells increases intracellular calcium without affecting cellular proliferation | Q40865162 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 2 | |
| P577 | publication date | 2016-02-16 | |
| P1433 | published in | Marine Drugs | Q2122804 |
| P1476 | title | Development of a Rapid Throughput Assay for Identification of hNav1.7 Antagonist Using Unique Efficacious Sodium Channel Agonist, Antillatoxin | |
| P478 | volume | 14 |
| Q39126913 | Bringing new dimensions to drug discovery screening: impact of cellular stimulation technologies |
| Q90019912 | Dehydrocrenatidine Inhibits Voltage-Gated Sodium Channels and Ameliorates Mechanic Allodia in a Rat Model of Neuropathic Pain |
| Q41045838 | Effects of Tetrodotoxin in Mouse Models of Visceral Pain. |
| Q90451672 | Emerging neurotechnology for antinoceptive mechanisms and therapeutics discovery |
| Q49306666 | Mechanism-specific assay design facilitates the discovery of Nav1.7-selective inhibitors. |
| Q48353819 | Phenytoin: a step by step insight into its multiple mechanisms of action-80 years of mechanistic studies in neuropharmacology. |
| Q48337085 | Sodium channels and pain: from toxins to therapies |
| Q89296981 | Veratridine modifies the gating of human voltage-gated sodium channel Nav1.7. |
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