human | Q5 |
P496 | ORCID iD | 0000-0001-7159-0288 |
P3829 | Publons author ID | 2444334 |
P1053 | ResearcherID | A-8385-2015 |
P166 | award received | Fellow of the American Association for the Advancement of Science | Q5442484 |
P69 | educated at | Dartmouth College | Q49116 |
California Institute of Technology | Q161562 | ||
University of Michigan | Q230492 | ||
P108 | employer | University of California, Irvine School of Medicine | Q7895169 |
P734 | family name | Goldin | Q21449952 |
P735 | given name | Alan | Q294833 |
Alan | Q294833 | ||
P106 | occupation | researcher | Q1650915 |
P21 | sex or gender | male | Q6581097 |
Q42540895 | A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS+) mutation |
Q37301303 | A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation |
Q49049294 | A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities |
Q48912148 | A missense mutation in the sodium channel Scn8a is responsible for cerebellar ataxia in the mouse mutant jolting. |
Q41700523 | A mutation that causes ataxia shifts the voltage-dependence of the Scn8a sodium channel |
Q37665790 | A neutral amino acid change in segment IIS4 dramatically alters the gating properties of the voltage-dependent sodium channel |
Q28291611 | A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for beta subunit interaction |
Q72608795 | A peptide segment critical for sodium channel inactivation functions as an inactivation gate in a potassium channel |
Q36385916 | A rat brain Na+ channel alpha subunit with novel gating properties |
Q46007688 | A voltage-dependent gating transition induces use-dependent block by tetrodotoxin of rat IIA sodium channels expressed in Xenopus oocytes. |
Q34731442 | A voltage-gated calcium-selective channel encoded by a sodium channel-like gene |
Q40857629 | Accessory subunits and sodium channel inactivation |
Q30493834 | Altered function of the SCN1A voltage-gated sodium channel leads to gamma-aminobutyric acid-ergic (GABAergic) interneuron abnormalities |
Q37347846 | Alternative polyadenylation signals in the 3' non-coding region of a voltage-gated potassium channel gene are major determinants of mRNA isoform expression |
Q34708118 | Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels |
Q37301144 | Amino acid residues required for fast Na(+)-channel inactivation: charge neutralizations and deletions in the III-IV linker |
Q30366738 | An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior. |
Q28300929 | An epilepsy mutation in the sodium channel SCN1A that decreases channel excitability |
Q41722487 | Blockade of neuronal sodium channels by the antiepileptic drugs phenytoin, carbamazepine and sodium valproate |
Q44525708 | Chapter 25 Expression of Ion Channels by Injection of mRNA into Xenopus Oocytes |
Q35236861 | Cloning of herpes simplex virus type 1 sequences representing the whole genome |
Q41789414 | Complex genetic interactions in a mouse model of absence epilepsy. |
Q52245979 | Developmental regulation of sodium channel expression in the rat forebrain. |
Q33691479 | Diversity of mammalian voltage-gated sodium channels. |
Q48628389 | Dopaminergic modulation of sodium current in hippocampal neurons via cAMP-dependent phosphorylation of specific sites in the sodium channel alpha subunit. |
Q43489970 | Effects of bisaramil, a novel class I antiarrhythmic agent, on heart, skeletal muscle and brain Na+ channels |
Q34572944 | Evolution of voltage-gated Na(+) channels |
Q24315122 | Expression and chromosomal localization of a lymphocyte K+ channel gene |
Q36980364 | Expression of herpes simplex virus beta and gamma genes integrated in mammalian cells and their induction by an alpha gene product. |
Q42540512 | Functional analysis of the mouse Scn8a sodium channel. |
Q42545515 | Functional analysis of the rat I sodium channel in xenopus oocytes. |
Q28188391 | Functional effects of two voltage-gated sodium channel mutations that cause generalized epilepsy with febrile seizures plus type 2 |
Q28204139 | Generalized epilepsy with febrile seizures plus type 2 mutation W1204R alters voltage-dependent gating of Na(v)1.1 sodium channels |
Q43782718 | Herpes simplex virus thymidine kinase gene is stably maintained and expressed in cells transformed by protoplast fusion |
Q36600234 | High-efficiency transfer of DNA into eukaryotic cells by protoplast fusion |
Q36957083 | High-frequency transfer of cloned herpes simplex virus type 1 sequences to mammalian cells by protoplast fusion. |
Q46052020 | High-level expression and detection of ion channels in Xenopus oocytes |
Q36434658 | Inactivation of cloned Na channels expressed in Xenopus oocytes |
Q40542880 | Increased neuronal firing in computer simulations of sodium channel mutations that cause generalized epilepsy with febrile seizures plus |
Q33907560 | Interaction between the sodium channel inactivation linker and domain III S4-S5. |
Q28289125 | International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels |
Q35600872 | International Union of Pharmacology. XXXIX. Compendium of voltage-gated ion channels: sodium channels. |
Q50795431 | Maintenance of Xenopus laevis and oocyte injection |
Q35172793 | Mechanisms of sodium channel inactivation |
Q24629483 | Messenger RNA coding for only the alpha subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes |
Q30460758 | Modulation of voltage-gated K+ channels by the sodium channel β1 subunit |
Q24672256 | Molecular analysis of the Na+ channel blocking actions of the novel class I anti-arrhythmic agent RSD 921 |
Q44241895 | Molecular basis of isoform-specific micro-conotoxin block of cardiac, skeletal muscle, and brain Na+ channels |
Q46771330 | Naloxone blockade of sodium currents expressed in Xenopus oocytes. |
Q28141860 | Nomenclature of voltage-gated sodium channels |
Q34669946 | Novel sodium channel gene mutations in Blattella germanica reduce the sensitivity of expressed channels to deltamethrin |
Q33922417 | Persistence of herpes simplex virus genes in cells of neuronal origin |
Q42441851 | Phosphorylation at a single site in the rat brain sodium channel is necessary and sufficient for current reduction by protein kinase A. |
Q45941245 | Phosphorylation of brain sodium channels in the I--II linker modulates channel function in Xenopus oocytes. |
Q48096142 | Point mutations in IIS4 alter activation and inactivation of rat brain IIA Na channels in Xenopus oocyte macropatches. |
Q33807882 | Potent and use-dependent block of cardiac sodium channels by U-50,488H, a benzeneacetamide kappa opioid receptor agonist |
Q41728588 | Potentiation of rat brain sodium channel currents by PKA in Xenopus oocytes involves the I-II linker. |
Q48588746 | Preparation of RNA for injection into Xenopus oocytes |
Q28186859 | Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel |
Q42452102 | Protein kinase A phosphorylation enhances sodium channel currents in Xenopus oocytes |
Q93509002 | Reply |
Q34142210 | Resurgence of sodium channel research |
Q46530230 | Role of the amino and carboxy termini in isoform-specific sodium channel variation |
Q33829255 | Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance |
Q37448824 | Role of the terminal domains in sodium channel localization. |
Q40082171 | Semliki Forest virus vectors with mutations in the nonstructural protein 2 gene permit extended superinfection of neuronal and non-neuronal cells. |
Q35787009 | Sequence variations at I260 and A1731 contribute to persistent currents in Drosophila sodium channels |
Q37220104 | Shaker-related potassium channels in the central medial nucleus of the thalamus are important molecular targets for arousal suppression by volatile general anesthetics |
Q46096043 | Site-directed mutagenesis of the putative pore region of the rat IIA sodium channel. |
Q37787324 | Sodium channel SCN1A and epilepsy: mutations and mechanisms |
Q36435921 | Sodium channel activation gating is affected by substitutions of voltage sensor positive charges in all four domains |
Q48852599 | Sodium channel blocking and antiarrhythmic actions of the novel arylpiperazine rsd992. |
Q33726588 | Sodium channel carboxyl-terminal residue regulates fast inactivation |
Q36435941 | Sodium channel inactivation is altered by substitution of voltage sensor positive charges |
Q44336170 | Spiradoline, a kappa opioid receptor agonist, produces tonic- and use-dependent block of sodium channels expressed in Xenopus oocytes |
Q45837889 | Stable induction of a 51K cellular protein in neuronal cells surviving herpes simplex virus type 1 infection |
Q34963077 | Substitutions in the domain III voltage-sensing module enhance the sensitivity of an insect sodium channel to a scorpion beta-toxin |
Q45955131 | The adult rat brain beta 1 subunit modifies activation and inactivation gating of multiple sodium channel alpha subunits. |
Q27339255 | The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant |
Q46208184 | Time- and voltage-dependent block of sodium channels expressed in Xenopus oocytes by RSD 921, a novel class I antiarrhythmic drug. |
Q34373977 | Tissue-specific expression of the RI and RII sodium channel subtypes |
Q36254560 | Topology of the Shaker potassium channel probed with hydrophilic epitope insertions |
Q36913463 | Transcriptional and genetic analyses of the herpes simplex virus type 1 genome: coordinates 0.29 to 0.45 |
Q44333617 | U-50,488H, a kappa opioid receptor agonist, is a more potent blocker of cardiac sodium channels than lidocaine. |
Q34188077 | Use-dependent potentiation of the Nav1.6 sodium channel |
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