Characterization of hepatitis C virus (HCV) and HCV E2 interactions with CD81 and the low-density lipoprotein receptor

scientific article

Characterization of hepatitis C virus (HCV) and HCV E2 interactions with CD81 and the low-density lipoprotein receptor is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/JVI.74.21.10055-10062.2000
P3181OpenCitations bibliographic resource ID1817997
P932PMC publication ID102044
P698PubMed publication ID11024134
P5875ResearchGate publication ID12299962

P2093author name stringD Klinzmann
J D Medh
J T Stapleton
S Wünschmann
W N Schmidt
P2860cites workBinding of hepatitis C virus to CD81Q22004178
Structure-function analysis of hepatitis C virus envelope-CD81 bindingQ24525189
Role of the extracellular domain of human herpesvirus 7 glycoprotein B in virus binding to cell surface heparan sulfate proteoglycansQ24673759
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Full-length GB virus C (Hepatitis G virus) RNA transcripts are infectious in primary CD4-positive T cellsQ27469312
Characterization of hepatitis G virus (GB-C virus) particles: evidence for a nucleocapsid and expression of sequences upstream of the E1 proteinQ27469553
Cell fusion activity of hepatitis C virus envelope proteinsQ27469594
Binding of hepatitis C virus E2 glycoprotein to CD81 does not correlate with species permissiveness to infectionQ27469669
Functional analysis of cell surface-expressed hepatitis C virus E2 glycoproteinQ27469721
Nonrandom distribution of hepatitis C virus quasispecies in plasma and peripheral blood mononuclear cell subsetsQ27469739
Lack of detection of negative-strand hepatitis C virus RNA in peripheral blood mononuclear cells and other extrahepatic tissues by the highly strand-specific rTth reverse transcriptase PCRQ27480320
Hepatitis C virus and other flaviviridae viruses enter cells via low density lipoprotein receptorQ27485871
Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexesQ27486195
CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune systemQ28271422
Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfateQ29618060
Prospective comparison of whole-blood- and plasma-based hepatitis C virus RNA detection systems: improved detection using whole blood as the source of viral RNA.Q33959072
Fluorescence-based quantitative methods for detecting human immunodeficiency virus type 1-induced syncytia.Q33968924
A27L protein mediates vaccinia virus interaction with cell surface heparan sulfateQ34070135
Detection of replicative intermediates of hepatitis C viral RNA in liver and serum of patients with chronic hepatitis CQ34200730
Microbial adherence to and invasion through proteoglycansQ35533138
CD81 on B cells promotes interleukin 4 secretion and antibody production during T helper type 2 immune responsesQ35921103
Normal lymphocyte development but delayed humoral immune response in CD81-null miceQ36377129
Correlation between the infectivity of hepatitis C virus in vivo and its infectivity in vitroQ36390620
Rotaviruses induce an early membrane permeabilization of MA104 cells and do not require a low intracellular Ca2+ concentration to initiate their replication cycle.Q36548599
Hepatitis C: progress and problemsQ36642065
Evidence for in vitro replication of hepatitis C virus genome in a human T-cell lineQ37061606
Efficient infection of cells in culture by type O foot-and-mouth disease virus requires binding to cell surface heparan sulfate.Q39875541
Suramin blocks hepatitis C binding to human hepatoma cells in vitroQ40972540
Low density lipoprotein receptor as a candidate receptor for hepatitis C virusQ40972546
Hepatitis C virus: detection of intracellular virus particles by electron microscopyQ41235560
Cell-surface heparan sulfate proteoglycan mediates HIV-1 infection of T-cell linesQ41577111
Hepatitis C: the clinical spectrum of diseaseQ41598735
Proteins are cointernalized with virion particles during early infectionQ41913367
Modification of membrane permeability during Semliki Forest virus infectionQ41916567
Visualization of hepatitis C virions and putative defective interfering particles isolated from low-density lipoproteinsQ42978052
Direct detection of hepatitis C virus (HCV) RNA from whole blood, and comparison with HCV RNA in plasma and peripheral blood mononuclear cells.Q42978951
Detection of replicative form of hepatitis C virus RNA in peripheral blood mononuclear cells.Q42981975
Association of hepatitis C virus in human sera with beta-lipoproteinQ42982426
A role for hepatitis C virus infection in type II cryoglobulinemiaQ42983385
Hepatitis C virus is detected in a monocyte/macrophage subpopulation of peripheral blood mononuclear cells of infected patientsQ42983474
Distribution of hepatitis C virus (HCV) RNA in whole blood and blood cell fractions: plasma HCV RNA analysis underestimates circulating virus loadQ42983600
Hepatitis C virus: buoyant density of the factor VIII-derived isolate in sucroseQ42984652
Association between hepatitis C virus and mixed cryoglobulinemia [see comment].Q42985058
Establishment of persistent hepatitis C virus infection and replication in vitro.Q42985215
Antibodies against hepatitis C virus in mixed cryoglobulinemia patientsQ42986062
Hepatitis C virus (HCV) infection and cryoglobulinemia: analysis of whole blood and plasma HCV-RNA concentrations and correlation with liver histologyQ42997613
In vitro infection of peripheral blood mononuclear cells by hepatitis C virusQ43037693
Peripheral blood leukocytes serve as a possible extrahepatic site for hepatitis C virus replicationQ43048290
Density heterogeneities of hepatitis C virus in human sera due to the binding of beta-lipoproteins and immunoglobulinsQ43049359
Clinical outcomes after transfusion-associated hepatitis C.Q44746801
Posttransfusion non-A, non-B hepatitis in chimpanzees. Physicochemical evidence that the tubule-forming agent is a small, enveloped virusQ45839124
First cysteine-rich repeat in ligand-binding domain of low density lipoprotein receptor binds Ca2+ and monoclonal antibodies, but not lipoproteins.Q52831885
Deletion in the gene for the low-density-lipoprotein receptor in a majority of French Canadians with familial hypercholesterolemiaQ69238529
Characterization of monoclonal antibodies against human low density lipoproteinQ72688759
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectvirologyQ7215
lipoproteinQ28350
hepatitis CQ154869
Hepatitis C virusQ708693
P304page(s)10055-62
P577publication date2000-11-01
P1433published inJournal of VirologyQ1251128
P1476titleCharacterization of hepatitis C virus (HCV) and HCV E2 interactions with CD81 and the low-density lipoprotein receptor
P478volume74

Reverse relations

cites work (P2860)
Q33648339A Sequence in the loop domain of hepatitis C virus E2 protein identified in silico as crucial for the selective binding to human CD81.
Q43042430A study of susceptibility of primary human Kupffer cells to hepatitis C virus
Q37805839Adaptive Immunity to the Hepatitis C Virus
Q44490223Additive inhibition of dendritic cell allostimulatory capacity by alcohol and hepatitis C is not restored by DC maturation and involves abnormal IL-10 and IL-2 induction
Q27477568An 85-aa segment of the GB virus type C NS5A phosphoprotein inhibits HIV-1 replication in CD4+ Jurkat T cells
Q38825949An insight into the molecular characteristics of hepatitis C virus for clinicians
Q27472891Analysis of antigenicity and topology of E2 glycoprotein present on recombinant hepatitis C virus-like particles
Q39912694Anti-CD81 antibodies can prevent a hepatitis C virus infection in vivo
Q27478309Apolipoprotein 3 allele is associated with persistent hepatitis C virus infection
Q27486923Apolipoprotein C1 Association with Hepatitis C Virus
Q27490234Apolipoprotein E on hepatitis C virion facilitates infection through interaction with low-density lipoprotein receptor
Q27473044Association between Hepatitis C Virus and Very-Low-Density Lipoprotein (VLDL)/LDL Analyzed in Iodixanol Density Gradients
Q44893793Association of hypocholesterolaemia with hepatitis C virus infection in HIV-infected people.
Q27472837Binding of hepatitis C virus-like particles derived from infectious clone H77C to defined human cell lines
Q27486525Binding of liver derived, low density hepatitis C virus to human hepatoma cells
Q35546564Bovine viral diarrhea virus as a surrogate model of hepatitis C virus for the evaluation of antiviral agents
Q40653700CD81 engineered with endocytotic signals mediates HCV cell entry: implications for receptor usage by HCV in vivo
Q29619745CD81 is required for hepatitis C virus glycoprotein-mediated viral infection
Q27485659CD81-Dependent Binding of Hepatitis C Virus E1E2 Heterodimers
Q36385222Cell entry of hepatitis C virus
Q43037514Cell surface expression of LDL receptor in chronic hepatitis C: correlation with viral load
Q37514366Cellular and molecular biology of HCV infection and hepatitis
Q38352468Cellular binding of hepatitis C virus envelope glycoprotein E2 requires cell surface heparan sulfate
Q40706735Cellular glycosaminoglycans and low density lipoprotein receptor are involved in hepatitis C virus adsorption
Q27472884Characterization of Low- and Very-Low-Density Hepatitis C Virus RNA-Containing Particles
Q27486387Characterization of a Peptide Domain within the GB Virus C NS5A Phosphoprotein that Inhibits HIV Replication
Q36598453Characterization of a peptide domain within the GB virus C envelope glycoprotein (E2) that inhibits HIV replication
Q27477720Characterization of an Immunodominant Antigenic Site on GB Virus C Glycoprotein E2 That Is Involved in Cell Binding
Q40539381Characterization of functional hepatitis C virus envelope glycoproteins.
Q27473226Characterization of the Early Steps of Hepatitis C Virus Infection by Using Luciferase Reporter Viruses
Q26784234Chronic hepatitis C virus infection and lipoprotein metabolism
Q27473461Complement-mediated enhancement of antibody function for neutralization of pseudotype virus containing hepatitis C virus E2 chimeric glycoprotein
Q36548487Correlation between beta-lipoprotein levels and outcome of hepatitis C treatment
Q40530808Diverse hepatitis C virus glycoproteins mediate viral infection in a CD81-dependent manner
Q27481043Do high lipids help clearance of hepatitis C?
Q36927297ERK signaling is triggered by hepatitis C virus E2 protein through DC-SIGN
Q46879484Effect of antiretroviral therapy and hepatitis c co-infection on changes in lipid levels in HIV-Infected patients 48 weeks after initiation of therapy
Q24674235Entry of feline calicivirus is dependent on clathrin-mediated endocytosis and acidification in endosomes
Q34004118Entry of hepatitis C virus and human immunodeficiency virus is selectively inhibited by carbohydrate-binding agents but not by polyanions
Q35621603Excess body weight, liver steatosis, and early fibrosis progression due to hepatitis C recurrence after liver transplantation
Q45729692Expression of human CD81 in transgenic mice does not confer susceptibility to hepatitis C virus infection
Q35059730Flow cytometric detection of hepatitis C virus antigens in infected peripheral blood leukocytes: binding and entry.
Q27469312Full-length GB virus C (Hepatitis G virus) RNA transcripts are infectious in primary CD4-positive T cells
Q33579851Functional selection of hepatitis C virus envelope E2-binding Peptide ligands by using ribosome display
Q36530370GB Virus Type C Envelope Protein E2 Elicits Antibodies That React with a Cellular Antigen on HIV-1 Particles and Neutralize Diverse HIV-1 Isolates
Q40589291HCV E2 glycoprotein: mutagenesis of N-linked glycosylation sites and its effects on E2 expression and processing
Q30438047HCV infection of the transplanted liver: changing CD81 and HVR1 variants immediately after liver transplantation
Q37829769HIV/hepatitis C virus and HIV/hepatitis B virus coinfections protect against antiretroviral-related hyperlipidaemia
Q90523108Hepatitis C Virus Entry: An Intriguingly Complex and Highly Regulated Process
Q36712605Hepatitis C infection is associated with lower lipids and high-sensitivity C-reactive protein in HIV-infected men
Q39755223Hepatitis C virus E2 has three immunogenic domains containing conformational epitopes with distinct properties and biological functions
Q38337047Hepatitis C virus NS5A-regulated gene expression and signaling revealed via microarray and comparative promoter analyses
Q43047968Hepatitis C virus and HIV envelope proteins collaboratively mediate interleukin-8 secretion through activation of p38 MAP kinase and SHP2 in hepatocytes
Q36946317Hepatitis C virus entry
Q34016463Hepatitis C virus entry: molecular mechanisms and targets for antiviral therapy
Q34235286Hepatitis C virus experimental model systems and antiviral drug research
Q24551041Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR
Q27477687Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
Q36244165Hepatitis C virus has a genetically determined lymphotropism through co-receptor B7.2.
Q38003914Hepatitis C virus: a new class of virus associated with particles derived from very low-density lipoproteins
Q34970582Hepatitis C: molecular virology and antiviral targets
Q26779128Host-Targeting Agents to Prevent and Cure Hepatitis C Virus Infection
Q34197528Human liver transplantation as a model to study hepatitis C virus pathogenesis
Q27477468Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding
Q27487399Identification of a Residue in Hepatitis C Virus E2 Glycoprotein That Determines Scavenger Receptor BI and CD81 Receptor Dependency and Sensitivity to Neutralizing Antibodies
Q24291799Identification of a hepatic factor capable of supporting hepatitis C virus replication in a nonpermissive cell line
Q34403294Identification of hepatitis C virus inhibitors targeting different aspects of infection using a cell-based assay
Q43039598Identification of human hepatocyte protein(s), which binds specifically to the recombinant envelope-2/non-structural-1 protein of hepatitis C virus
Q27472909Identification of the hepatitis C virus E2 glycoprotein binding site on the large extracellular loop of CD81
Q50934385Immunopathogenesis of Hepatitis C Virus Infection.
Q59200582Immunopathogenesis of hepatitis C virus infection
Q40211269Immunopathogenesis of hepatitis C virus infection and hepatic fibrosis: New insights into antifibrotic therapy in chronic hepatitis C.
Q26864485Impact of lipids and lipoproteins on hepatitis C virus infection and virus neutralization
Q34422731In search of hepatitis C virus receptor(s).
Q35716330Infection of Human Liver Myofibroblasts by Hepatitis C Virus: A Direct Mechanism of Liver Fibrosis in Hepatitis C
Q34295937Infectivity of hepatitis C virus is influenced by association with apolipoprotein E isoforms.
Q30767073Inhibition of hepatitis C virus-like particle binding to target cells by antiviral antibodies in acute and chronic hepatitis C.
Q34772253Interaction between hepatitis C virus proteins and host cell factors
Q42827093Interaction of L-SIGN with hepatitis C virus envelope protein E2 up-regulates Raf-MEK-ERK pathway
Q27472900Interaction of hepatitis C virus-like particles and cells: a model system for studying viral binding and entry
Q35195465Lipid Profiles and Hepatitis C Viral Markers in HCV-Infected Thalassemic Patients
Q36010861Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus
Q38166372Lipoprotein receptors and lipid enzymes in hepatitis C virus entry and early steps of infection
Q42997915Liver endothelial cells promote LDL-R expression and the uptake of HCV-like particles in primary rat and human hepatocytes.
Q35669529Mechanisms of hepatitis C virus infection
Q39692571Morphological characterization and fusion properties of triglyceride-rich lipoproteins obtained from cells transduced with hepatitis C virus glycoproteins
Q38109628New insights in recurrent HCV infection after liver transplantation
Q29620681Novel insights into hepatitis C virus replication and persistence
Q24795289Potential cellular receptors involved in hepatitis C virus entry into cells
Q34576190Potential treatment options and future research to increase hepatitis C virus treatment response rate
Q37352203Primary hepatocytes as targets for hepatitis C virus replication
Q27473382Primary hepatocytes of Tupaia belangeri as a potential model for hepatitis C virus infection
Q57568884Rationale and Design of LAPLACE-2: A Phase 3, Randomized, Double-Blind, Placebo- and Ezetimibe-Controlled Trial Evaluating the Efficacy and Safety of Evolocumab in Subjects With Hypercholesterolemia on Background Statin Therapy
Q36956517Recent advances in our understanding of receptor binding, viral fusion and cell entry of hepatitis C virus: new targets for the design of antiviral agents
Q27473084Recognition of native hepatitis C virus E1E2 heterodimers by a human monoclonal antibody.
Q30375044Recombinant hepatitis C virus-envelope protein 2 interactions with low-density lipoprotein/CD81 receptors.
Q40573089Recombinant hepatitis C virus-like particles expressed by baculovirus: utility in cell-binding and antibody detection assays.
Q40585135Reconstitution of hepatitis C virus envelope glycoproteins into liposomes as a surrogate model to study virus attachment
Q21090530Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus
Q27485298Serum-Derived Hepatitis C Virus Infection of Primary Human Hepatocytes Is Tetraspanin CD81 Dependent
Q30756955Structural characterization of peptide fragments from hCD81-LEL.
Q27481034Studying Hepatitis C Virus: Making the Best of a Bad Virus
Q27478383Sulfated Homologues of Heparin Inhibit Hepatitis C Virus Entry into Mammalian Cells
Q27470936Tetraspanins in viral infections: a fundamental role in viral biology?
Q24609524The GB viruses: a review and proposed classification of GBV-A, GBV-C (HGV), and GBV-D in genus Pegivirus within the family Flaviviridae
Q34158687The rate of hepatitis C virus infection initiation in vitro is directly related to particle density.
Q44054976Translated Alu sequence determines nuclear localization of a novel catalytic subunit of casein kinase 2.
Q38350416Tropism of human pegivirus (formerly known as GB virus C/hepatitis G virus) and host immunomodulation: insights into a highly successful viral infection.
Q41926409Yellow fever virus, but not Zika or Dengue virus inhibits T cell receptor-mediated T cell function by an RNA-based mechanism
Q78318877[Interaction of the hepatitis C virus with the cellular membrane]

Search more.