Mechanisms of hepatitis C virus infection

scientific article published on November 2003

Mechanisms of hepatitis C virus infection is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1177/095632020301400601
P698PubMed publication ID14968935
P5875ResearchGate publication ID8164022

P50authorYoshiharu MatsuuraQ60077839
P2093author name stringKohji Moriishi
P2860cites workBinding of hepatitis C virus to CD81Q22004178
Inhibition of the interferon-inducible protein kinase PKR by HCV E2 proteinQ22010192
Characterization of truncated forms of hepatitis C virus glycoproteins.Q41091382
High titers of antibodies inhibiting the binding of envelope to human cells correlate with natural resolution of chronic hepatitis C.Q42990186
Sequence motifs required for lipid droplet association and protein stability are unique to the hepatitis C virus core proteinQ42999372
RNA interference in adult mice.Q43038702
Hepatitis C virus in multiple episodes of acute hepatitis in polytransfused thalassaemic childrenQ43041183
Targeting presenilin-type aspartic protease signal peptide peptidase with gamma-secretase inhibitorsQ44350630
Modified apoptotic molecule (BID) reduces hepatitis C virus infection in mice with chimeric human liversQ44409476
Expression of human CD81 in transgenic mice does not confer susceptibility to hepatitis C virus infectionQ45729692
Membrane topology of the hepatitis C virus NS2 proteinQ45732027
Combination therapy of chronic hepatitis C: an important step but not the final goal!Q50587922
Human Cytomegalovirus Binding to DC-SIGN Is Required for Dendritic Cell Infection and Target Cell trans-InfectionQ57083074
T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infectionsQ58802894
Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferationQ24290542
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virusQ24307963
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosisQ24310597
Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A proteinQ24319002
Identification of amino acid residues in CD81 critical for interaction with hepatitis C virus envelope glycoprotein E2.Q24524809
Structure-function analysis of hepatitis C virus envelope-CD81 bindingQ24525189
Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid dropletsQ24534284
Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complexQ24537657
C-type lectins DC-SIGN and L-SIGN mediate cellular entry by Ebola virus in cis and in transQ24537682
Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNRQ24551041
DC-SIGN (CD209) mediates dengue virus infection of human dendritic cellsQ24673466
Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexesQ24673768
Characterization of hepatitis C virus (HCV) and HCV E2 interactions with CD81 and the low-density lipoprotein receptorQ27469307
Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulationQ27469500
Cell fusion activity of hepatitis C virus envelope proteinsQ27469594
Subcellular localization, stability, and trans-cleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell linesQ27469636
E2-p7 region of the bovine viral diarrhea virus polyprotein: processing and functional studiesQ27469693
Mutations in Hepatitis C Virus RNAs Conferring Cell Culture AdaptationQ27469769
Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutationsQ27469794
Assembly and Maturation of the Flavivirus Kunjin Virus Appear To Occur in the Rough Endoplasmic Reticulum and along the Secretory Pathway, RespectivelyQ27469877
Effect of alpha interferon on the hepatitis C virus repliconQ27469963
Sequences in the 5' nontranslated region of hepatitis C virus required for RNA replication.Q27469999
Topological changes in the transmembrane domains of hepatitis C virus envelope glycoproteinsQ27472616
Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAsQ27472783
Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cellsQ27472846
Subcellular Localization and Topology of the p7 Polypeptide of Hepatitis C VirusQ27472868
Persistent and transient replication of full-length hepatitis C virus genomes in cell cultureQ27472869
Characterization of Low- and Very-Low-Density Hepatitis C Virus RNA-Containing ParticlesQ27472884
Characterization of vesicular stomatitis virus recombinants that express and incorporate high levels of hepatitis C virus glycoproteinsQ27472885
Interaction of hepatitis C virus-like particles and cells: a model system for studying viral binding and entryQ27472900
Diverging Effects of Human Recombinant Anti-Hepatitis C Virus (HCV) Antibody Fragments Derived from a Single Patient on the Infectivity of a Vesicular Stomatitis Virus/HCV PseudotypeQ27472930
Genetic Analysis of Sequences in the 3' Nontranslated Region of Hepatitis C Virus That Are Important for RNA ReplicationQ27472973
Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzeesQ27473004
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAsQ27473092
Efficient Replication of Hepatitis C Virus Genotype 1a RNAs in Cell CultureQ27473339
Viral and Cellular Determinants of Hepatitis C Virus RNA Replication in Cell CultureQ27473345
Interference of hepatitis C virus RNA replication by short interfering RNAsQ27473349
L-SIGN (CD 209L) is a liver-specific capture receptor for hepatitis C virusQ27473455
Replication Studies Using Genotype 1a Subgenomic Hepatitis C Virus RepliconsQ27473475
The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivativesQ27477454
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particlesQ27477687
Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A regionQ27478292
Inhibition of Natural Killer Cells through Engagement of CD81 by the Major Hepatitis C Virus Envelope ProteinQ27485143
Binding of the Hepatitis C Virus Envelope Protein E2 to CD81 Inhibits Natural Killer Cell FunctionsQ27485145
Hepatitis C virus and other flaviviridae viruses enter cells via low density lipoprotein receptorQ27485871
In vivo analysis of the 3' untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA cloneQ27488360
Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzeesQ27489101
Efficient initiation of HCV RNA replication in cell cultureQ27860520
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell lineQ27860561
Analysis of successful immune responses in persons infected with hepatitis C virusQ27860698
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegansQ27860867
Determinants of viral clearance and persistence during acute hepatitis C virus infectionQ28131757
DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cellsQ28138968
Intramembrane proteolysis of signal peptides: an essential step in the generation of HLA-E epitopesQ28206209
Identification of signal peptide peptidase, a presenilin-type aspartic proteaseQ28206228
Novel class of polytopic proteins with domains associated with putative protease activityQ28215912
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosisQ28511080
Mycobacteria target DC-SIGN to suppress dendritic cell functionQ28616857
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervalsQ29547713
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cellsQ29547714
Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine ProteaseQ29614208
A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cellsQ29615897
Analysis of a successful immune response against hepatitis C virusQ29619507
Genetic Heterogeneity of Hepatitis C Virus: Quasispecies and GenotypesQ29619748
Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis CQ29620614
An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5AQ29620628
The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, AmantadineQ29620670
Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infectionQ29620702
Lack of Protective Immunity Against Reinfection with Hepatitis C VirusQ29620909
Expression, identification and subcellular localization of the proteins encoded by the hepatitis C viral genomeQ29620976
The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytesQ30004698
Hepatitis C virus core protein inhibits human T lymphocyte responses by a complement-dependent regulatory pathwayQ30308176
The hepatitis C virus nonstructural protein 4B is an integral endoplasmic reticulum membrane proteinQ30667774
Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence.Q33720363
Early events in hepatitis C virus infection of chimpanzees.Q33755441
The NS3/4A proteinase of the hepatitis C virus: unravelling structure and function of an unusual enzyme and a prime target for antiviral therapyQ33801327
Interaction of hepatitis C virus proteins with host cell membranes and lipidsQ34160337
RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cellsQ34178401
RNA interference: the new somatic cell genetics?Q34768636
Hepatitis C virus therapies: current treatments, targets and future perspectivesQ35147050
Foreign glycoproteins expressed from recombinant vesicular stomatitis viruses are incorporated efficiently into virus particlesQ37249987
Selective binding of hepatitis C virus core protein to synthetic oligonucleotides corresponding to the 5' untranslated region of the viral genomeQ38313136
Analysis of the glycosylation sites of hepatitis C virus (HCV) glycoprotein E1 and the influence of E1 glycans on the formation of the HCV glycoprotein complex.Q38325724
Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN, CD209), a C-type surface lectin in human DCs, is a receptor for Leishmania amastigotes.Q40578638
Characterization of pseudotype VSV possessing HCV envelope proteinsQ40598617
Inhibition of hepatitis B virus in mice by RNA interferenceQ40648698
Modulation of HIV-1 replication by RNA interferenceQ40721798
Short interfering RNA confers intracellular antiviral immunity in human cellsQ40721804
siRNA-directed inhibition of HIV-1 infectionQ40727988
Structural proteins of hepatitis C virusQ40729931
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cellsQ40735249
Determinants for membrane association of the hepatitis C virus RNA-dependent RNA polymeraseQ40780476
Hepatitis C virus structural proteins reside in the endoplasmic reticulum as well as in the intermediate compartment/cis-Golgi complex region of stably transfected cellsQ40829716
P433issue6
P921main subjecthepatitis CQ154869
Hepatitis C virusQ708693
P304page(s)285-297
P577publication date2003-11-01
P1433published inAntiviral Chemistry & ChemotherapyQ2853412
P1476titleMechanisms of hepatitis C virus infection
P478volume14

Reverse relations

cites work (P2860)
Q24307609A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replication
Q39366642CD44 participates in IP-10 induction in cells in which hepatitis C virus RNA is replicating, through an interaction with Toll-like receptor 2 and hyaluronan
Q47350163Characterization of SPP inhibitors suppressing propagation of HCV and protozoa.
Q39458949Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus
Q33799276Elimination of hepatitis C virus from hepatocytes by a selective activation of therapeutic molecules
Q39437753Establishment of a novel permissive cell line for the propagation of hepatitis C virus by expression of microRNA miR122.
Q84036104Expression of toll-like receptor 9 in peripheral blood mononuclear cells from patients with different hepatitis B and C viral loads
Q35040828GPS2 is required for the association of NS5A with VAP-A and hepatitis C virus replication
Q24306116Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90
Q24310415Hepatitis C virus nonstructural protein 5A modulates the toll-like receptor-MyD88-dependent signaling pathway in macrophage cell lines
Q36847659Host factors involved in the replication of hepatitis C virus
Q24338324Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B
Q24337683Human VAP-C negatively regulates hepatitis C virus propagation
Q24305040Human butyrate-induced transcript 1 interacts with hepatitis C virus NS5A and regulates viral replication
Q40211269Immunopathogenesis of hepatitis C virus infection and hepatic fibrosis: New insights into antifibrotic therapy in chronic hepatitis C.
Q35376259Interactions between Hsp90 and oncogenic viruses: implications for viral cancer therapeutics
Q40206509Interactome of the hepatitis C virus: Literature mining with ANDSystem
Q24658154Intramembrane processing by signal peptide peptidase regulates the membrane localization of hepatitis C virus core protein and viral propagation
Q21560973Intrinsically unstructured domain 3 of hepatitis C Virus NS5A forms a "fuzzy complex" with VAPB-MSP domain which carries ALS-causing mutations
Q27477612Oligomerization of Hepatitis C Virus Core Protein Is Crucial for Interaction with the Cytoplasmic Domain of E1 Envelope Protein
Q24795289Potential cellular receptors involved in hepatitis C virus entry into cells
Q27481021Replication-Competent Recombinant Vesicular Stomatitis Virus Encoding Hepatitis C Virus Envelope Proteins
Q30155273VAPC, an human endogenous inhibitor for hepatitis C virus (HCV) infection, is intrinsically unstructured but forms a "fuzzy complex" with HCV NS5B.

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