scholarly article | Q13442814 |
P356 | DOI | 10.1111/J.1747-0285.2008.00679.X |
P8608 | Fatcat ID | release_iwlrto6bfja4rbiewlikt3wcji |
P932 | PMC publication ID | 2597651 |
P698 | PubMed publication ID | 18611220 |
P5875 | ResearchGate publication ID | 5239994 |
P50 | author | Jennifer Barrila | Q61108512 |
Ernesto Freire | Q88552340 | ||
Usman Bacha | Q114432363 | ||
L. Mario Amzel | Q28031687 | ||
Sandra B. Gabelli | Q38319720 | ||
P2093 | author name string | Yoshiaki Kiso | |
P2860 | cites work | Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia | Q24558699 |
Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate | Q44899503 | ||
Design, synthesis, and evaluation of inhibitors for severe acute respiratory syndrome 3C-like protease based on phthalhydrazide ketones or heteroaromatic esters | Q45098665 | ||
Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization. Biochemical and thermodynamic investigation in conjunction with molecular dynamics simulations | Q45126666 | ||
Mechanism of the maturation process of SARS-CoV 3CL protease | Q46402178 | ||
Determination of the rate constant of enzyme modification by measuring the substrate reaction in the presence of the modifier. | Q52723774 | ||
Coronavirus Protein Processing and RNA Synthesis Is Inhibited by the Cysteine Proteinase Inhibitor E64d | Q57995967 | ||
A catalytic mechanism for caspase-1 and for bimodal inhibition of caspase-1 by activated aspartic ketones | Q77827678 | ||
Synthesis of glutamic acid and glutamine peptides possessing a trifluoromethyl ketone group as SARS-CoV 3CL protease inhibitors | Q91900164 | ||
Design of wide-spectrum inhibitors targeting coronavirus main proteases | Q24817106 | ||
Improved methods for building protein models in electron density maps and the location of errors in these models | Q26776980 | ||
Processing of X-ray diffraction data collected in oscillation mode | Q26778468 | ||
Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain | Q27639290 | ||
Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs | Q27641252 | ||
Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors | Q27648126 | ||
Binding of chloromethyl ketone substrate analogues to crystalline papain | Q27749019 | ||
ARP/wARP and molecular replacement | Q27860622 | ||
The CCP4 suite: programs for protein crystallography | Q27861090 | ||
Coronavirus as a possible cause of severe acute respiratory syndrome | Q28200848 | ||
Characterization of a novel coronavirus associated with severe acute respiratory syndrome | Q28202401 | ||
Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage | Q29615331 | ||
Identification of a new human coronavirus | Q29615906 | ||
The Genome sequence of the SARS-associated coronavirus | Q29619007 | ||
Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyprotein | Q30194279 | ||
Quaternary structure, substrate selectivity and inhibitor design for SARS 3C-like proteinase | Q33266597 | ||
Virus-encoded proteinases and proteolytic processing in the Nidovirales. | Q33867985 | ||
Biosynthesis, Purification, and Substrate Specificity of Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase | Q34270281 | ||
The common cold: a review of the literature | Q34323845 | ||
MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity | Q35045715 | ||
The molecular biology of coronaviruses | Q36550910 | ||
A contemporary view of coronavirus transcription. | Q36575146 | ||
The relationship of severe acute respiratory syndrome coronavirus with avian and other coronaviruses | Q36622855 | ||
Long-range cooperative interactions modulate dimerization in SARS 3CLpro. | Q36943869 | ||
Biosynthesis, purification, and characterization of the human coronavirus 229E 3C-like proteinase. | Q39879482 | ||
Current problems in mechanistic studies of serine and cysteine proteinases | Q40250485 | ||
Calpain activation is upstream of caspases in radiation-induced apoptosis. | Q40979319 | ||
Synthesis of peptide fluoromethyl ketones and the inhibition of human cathepsin B. | Q42229796 | ||
Conservation of substrate specificities among coronavirus main proteases | Q43884469 | ||
pH-dependent conformational flexibility of the SARS-CoV main proteinase (M(pro)) dimer: molecular dynamics simulations and multiple X-ray structure analyses | Q43919382 | ||
REMOVED: SARS Epidemiology From descriptive to mechanistic analyses | Q44100860 | ||
3C-like proteinase from SARS coronavirus catalyzes substrate hydrolysis by a general base mechanism | Q44839752 | ||
Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro. | Q44861300 | ||
P433 | issue | 1 | |
P921 | main subject | Coronaviridae | Q1134583 |
P304 | page(s) | 34-49 | |
P577 | publication date | 2008-07-01 | |
P1433 | published in | Chemical Biology and Drug Design | Q15749458 |
P1476 | title | Development of Broad-Spectrum Halomethyl Ketone Inhibitors Against Coronavirus Main Protease 3CLpro | |
P478 | volume | 72 |
Q30357066 | Atlas of coronavirus replicase structure. |
Q35488987 | Broad-spectrum inhibitors against 3C-like proteases of feline coronaviruses and feline caliciviruses. |
Q37336376 | Chimeric exchange of coronavirus nsp5 proteases (3CLpro) identifies common and divergent regulatory determinants of protease activity |
Q34652825 | Crystallization and preliminary crystallographic study of Porcine epidemic diarrhea virus main protease in complex with an inhibitor |
Q47932523 | Design and synthesis of new tripeptide-type SARS-CoV 3CL protease inhibitors containing an electrophilic arylketone moiety |
Q46223071 | Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: structure-activity relationship study |
Q94595594 | Designing of improved drugs for COVID-19: Crystal structure of SARS-CoV-2 main protease Mpro |
Q42272988 | Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: design, synthesis, biological evaluation, and docking studies |
Q43914013 | Differential domain structure stability of the severe acute respiratory syndrome coronavirus papain-like protease |
Q26992345 | From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug design |
Q94503709 | Genomics functional analysis and drug screening of SARS-CoV-2 |
Q37593477 | Inhibitors of SARS-3CLpro: virtual screening, biological evaluation, and molecular dynamics simulation studies |
Q27660870 | Mutation of Asn28 Disrupts the Dimerization and Enzymatic Activity of SARS 3CL pro |
Q33767743 | Mutation of Glu-166 blocks the substrate-induced dimerization of SARS coronavirus main protease. |
Q35620215 | New developments for the design, synthesis and biological evaluation of potent SARS-CoV 3CL(pro) inhibitors |
Q59354020 | Porcine epidemic diarrhea virus papain-like protease 2 can be noncompetitively inhibited by 6-thioguanine |
Q97552375 | SARS-CoV and SARS-CoV-2 main protease residue interaction networks change when bound to inhibitor N3 |
Q89878619 | Structural Basis for Inhibiting Porcine Epidemic Diarrhea Virus Replication with the 3C-Like Protease Inhibitor GC376 |
Q42858751 | Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors |
Q43056416 | Synthesis, docking studies, and evaluation of pyrimidines as inhibitors of SARS-CoV 3CL protease |
Q35943856 | Temperature-sensitive mutants and revertants in the coronavirus nonstructural protein 5 protease (3CLpro) define residues involved in long-distance communication and regulation of protease activity |
Q34455805 | Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus |
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