| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1048118945 |
| P356 | DOI | 10.1038/NATURE07254 |
| P3181 | OpenCitations bibliographic resource ID | 4564355 |
| P698 | PubMed publication ID | 18758443 |
| P50 | author | Osamu Nureki | Q28036462 |
| P2093 | author name string | Kazuhiro Iwai | |
| Masayuki Komada | |||
| Shuya Fukai | |||
| Yusuke Sato | |||
| Atsushi Yamagata | |||
| Masami Yamashita | |||
| Azusa Yoshikawa | |||
| Hisatoshi Mimura | |||
| Kayoko Ookata | |||
| P2860 | cites work | JAMM: a metalloprotease-like zinc site in the proteasome and signalosome | Q21092836 |
| MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function | Q21284393 | ||
| The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction | Q24292709 | ||
| RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites | Q24306789 | ||
| The crystal structure of the human Mov34 MPN domain reveals a metal-free dimer | Q24309182 | ||
| STAM-AMSH interaction facilitates the deubiquitination activity in the C-terminal AMSH | Q24310796 | ||
| A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation | Q24337802 | ||
| Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex | Q24654714 | ||
| AMSH is an endosome-associated ubiquitin isopeptidase | Q24676880 | ||
| A short history of SHELX | Q25938995 | ||
| Processing of X-ray diffraction data collected in oscillation mode | Q26778468 | ||
| Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde | Q27640257 | ||
| Structure of the Jab1/MPN Domain and Its Implications for Proteasome Function | Q27642237 | ||
| Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa | Q27643886 | ||
| Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants | Q27644658 | ||
| Structural Basis for Ubiquitin Recognition by the Otu1 Ovarian Tumor Domain Protein | Q27649839 | ||
| Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues | Q27728601 | ||
| Coot: model-building tools for molecular graphics | Q27860505 | ||
| Methods used in the structure determination of bovine mitochondrial F1 ATPase | Q27860644 | ||
| Refinement of macromolecular structures by the maximum-likelihood method | Q27861011 | ||
| ARP/wARP and automatic interpretation of protein electron density maps | Q27861049 | ||
| Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome | Q27937927 | ||
| A cryptic protease couples deubiquitination and degradation by the proteasome | Q27938068 | ||
| The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin | Q27939113 | ||
| Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain | Q28119149 | ||
| A genomic and functional inventory of deubiquitinating enzymes | Q28284911 | ||
| Mechanism and function of deubiquitinating enzymes | Q28295758 | ||
| Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes | Q28511379 | ||
| Ubiquitin-binding domains | Q29616461 | ||
| Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation | Q29619698 | ||
| Protein regulation by monoubiquitin | Q29620221 | ||
| MOLREP: an Automated Program for Molecular Replacement | Q29642797 | ||
| Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate | Q34365924 | ||
| Regulation of receptors and transporters by ubiquitination: new insights into surprisingly similar mechanisms | Q34645723 | ||
| Endocytosis: the DUB version | Q36601432 | ||
| Quantitative structure-activity relationship studies on zinc-containing metalloproteinase inhibitors | Q36875933 | ||
| ESCRTing proteins in the endocytic pathway | Q36995735 | ||
| Controlling receptor downregulation by ubiquitination and deubiquitination | Q37184823 | ||
| Mechanism of Lys48-linked polyubiquitin chain recognition by the Mud1 UBA domain | Q42139176 | ||
| Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling | Q42614287 | ||
| In vitro assembly and recognition of Lys-63 polyubiquitin chains | Q43615489 | ||
| Structural basis for distinct roles of Lys63- and Lys48-linked polyubiquitin chains. | Q45088254 | ||
| Structural determinants for selective recognition of a Lys48-linked polyubiquitin chain by a UBA domain | Q46539684 | ||
| Controlled synthesis of polyubiquitin chains | Q46843256 | ||
| Improvement of macromolecular electron-density maps by the simultaneous application of real and reciprocal space constraints. | Q52403123 | ||
| [27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods. | Q55059918 | ||
| Recent Advances in Zinc Enzymology | Q77646423 | ||
| P433 | issue | 7211 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 358-62 | |
| P577 | publication date | 2008-09-18 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains | |
| P478 | volume | 455 |
| Q58695813 | A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes |
| Q39016031 | A native chemical ligation handle that enables the synthesis of advanced activity-based probes: diubiquitin as a case study |
| Q41945493 | A set of surgical chain saws |
| Q41936075 | Activity-based diubiquitin probes for elucidating the linkage specificity of deubiquitinating enzymes |
| Q34132731 | An RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-κB activation |
| Q27676107 | An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains |
| Q41971949 | Archaeal JAB1/MPN/MOV34 metalloenzyme (HvJAMM1) cleaves ubiquitin-like small archaeal modifier proteins (SAMPs) from protein-conjugates |
| Q38193464 | Architecture and function of metallopeptidase catalytic domains |
| Q36568548 | Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition. |
| Q38028343 | Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages. |
| Q63384377 | Breaking the chains: deubiquitylating enzyme specificity begets function |
| Q28131738 | Breaking the chains: structure and function of the deubiquitinases |
| Q42791381 | Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. |
| Q44552006 | Characterizing polyubiquitinated forms of the neurodegenerative ubiquitin mutant UBB+1. |
| Q38799376 | Chemical and semisynthetic approaches to study and target deubiquitinases. |
| Q38840548 | Chemical ubiquitination for decrypting a cellular code |
| Q38018581 | Chemistry and biology of the ubiquitin signal |
| Q34221890 | Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth |
| Q57100445 | Collaborating genomic, transcriptomic and microbiomic alterations lead to canine extreme intestinal polyposis |
| Q35823044 | Comparison of native and non-native ubiquitin oligomers reveals analogous structures and reactivities |
| Q28292908 | Conformational switching of the 26S proteasome enables substrate degradation |
| Q37813020 | Connecting the Dots: Interplay between Ubiquitylation and SUMOylation at DNA Double-Strand Breaks |
| Q90579800 | Connexin-43 K63-polyubiquitylation on lysines 264 and 303 regulates gap junction internalization |
| Q33903347 | Control of B cell development by the histone H2A deubiquitinase MYSM1. |
| Q27657476 | Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin |
| Q27694578 | Crystal structure of the human COP9 signalosome |
| Q27681666 | Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11 |
| Q27657332 | Crystal structures of Lys-63-linked tri- and di-ubiquitin reveal a highly extended chain architecture |
| Q37538046 | DUBs at a glance |
| Q38336126 | DUBs, the regulation of cell identity and disease |
| Q24567788 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome |
| Q36536393 | Design principles of a universal protein degradation machine |
| Q41015604 | Deubiquitinase-based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest). |
| Q38326071 | Deubiquitinases and the new therapeutic opportunities offered to cancer |
| Q37945451 | Deubiquitinases in cancer: new functions and therapeutic options. |
| Q26801232 | Deubiquitinating enzymes in cellular signaling and disease regulation |
| Q38125278 | Deubiquitylases from genes to organism |
| Q38193809 | Deubiquitylating enzymes and their emerging role in plant biology |
| Q34155439 | Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex |
| Q27935947 | Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6. |
| Q36278259 | Discovery of an Inhibitor of the Proteasome Subunit Rpn11. |
| Q51585257 | Divergence in Ubiquitin Interaction and Catalysis among the Ubiquitin-Specific Protease Family Deubiquitinating Enzymes. |
| Q37804581 | Divergent pathways lead to ESCRT-III-catalyzed membrane fission |
| Q37130380 | Dynamics of an Active-Site Flap Contributes to Catalysis in a JAMM Family Metallo Deubiquitinase |
| Q47967150 | ESCRT-dependent cargo sorting at multivesicular endosomes. |
| Q48185904 | Endosomal Rab cycles regulate Parkin-mediated mitophagy. |
| Q27664221 | Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase |
| Q24310203 | Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1 |
| Q34010890 | Evolution of the deaminase fold and multiple origins of eukaryotic editing and mutagenic nucleic acid deaminases from bacterial toxin systems |
| Q33675074 | Expression of MYSM1 is associated with tumor progression in colorectal cancer. |
| Q35739138 | Extended ubiquitin species are protein-based DUB inhibitors |
| Q42696204 | Forging isopeptide bonds using thiol-ene chemistry: site-specific coupling of ubiquitin molecules for studying the activity of isopeptidases |
| Q37702075 | Gene expression profiling of hematologic malignant cell lines resistant to oncolytic virus treatment |
| Q27704901 | Genetically Directed Production of Recombinant, Isosteric and Nonhydrolysable Ubiquitin Conjugates |
| Q24304441 | Global profiling of co- and post-translationally N-myristoylated proteomes in human cells |
| Q46823938 | Harnessing the oxidation susceptibility of deubiquitinases for inhibition with small molecules |
| Q36084899 | Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. |
| Q37896711 | How ubiquitin functions with ESCRTs |
| Q37405033 | Identification of two pentatricopeptide repeat genes required for RNA editing and zinc binding by C-terminal cytidine deaminase-like domains. |
| Q83231035 | In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation |
| Q27675408 | Insights into noncanonical E1 enzyme activation from the structure of autophagic E1 Atg7 with Atg8 |
| Q27683606 | Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product |
| Q27675751 | Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1 |
| Q91862920 | K63-Linked Ubiquitin Is Required for Restriction of HIV-1 Reverse Transcription and Capsid Destabilization by Rhesus TRIM5α |
| Q35971438 | K63-linked ubiquitination in kinase activation and cancer |
| Q24310641 | K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1 |
| Q26824916 | Key role for ubiquitin protein modification in TGFβ signal transduction |
| Q42080792 | Linkage-specific avidity defines the lysine 63-linked polyubiquitin-binding preference of rap80. |
| Q35867082 | Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition |
| Q37203860 | Lysine 63-linked polyubiquitination is required for EGF receptor degradation |
| Q37679390 | Mechanism of recruitment and activation of the endosome-associated deubiquitinase AMSH. |
| Q47292178 | Meddling with Fate: The Proteasomal Deubiquitinating Enzymes |
| Q41896296 | Modifying the vicinity of the isopeptide bond to reveal differential behavior of ubiquitin chains with interacting proteins: organic chemistry applied to synthetic proteins |
| Q39355026 | Molecular Basis for K63-Linked Ubiquitination Processes in Double-Strand DNA Break Repair: A Focus on Kinetics and Dynamics. |
| Q24316967 | Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains |
| Q35738601 | Molecular mechanisms of ubiquitin-dependent membrane traffic |
| Q36723224 | Myosin VI Contains a Compact Structural Motif that Binds to Ubiquitin Chains |
| Q44104911 | NMR analysis of Lys63-linked polyubiquitin recognition by the tandem ubiquitin-interacting motifs of Rap80. |
| Q30524942 | Near-atomic resolution structural model of the yeast 26S proteasome. |
| Q35545518 | Nipped in the bud: how the AMSH MIT domain helps deubiquitinate lysosome-bound cargo |
| Q33852992 | Nonenzymatic polymerization of ubiquitin: single-step synthesis and isolation of discrete ubiquitin oligomers |
| Q57471970 | POH1 deubiquitinates pro-interleukin-1β and restricts inflammasome activity |
| Q36839501 | POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation |
| Q49539596 | Plant Deubiquitinases and Their Role in the Control of Gene Expression Through Modification of Histones |
| Q37401250 | Polyubiquitin binding and disassembly by deubiquitinating enzymes |
| Q26998484 | Prokaryotic ubiquitin-like protein modification |
| Q89925905 | Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond |
| Q35687416 | Rapid optimization of labeled ubiquitinated peptides for monitoring deubiquitinases activities |
| Q33760446 | Recent advances in polyubiquitin chain recognition |
| Q26738716 | Recent advances in the structural biology of the 26S proteasome |
| Q36923194 | Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease |
| Q24645701 | Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes |
| Q38120938 | Regulation of proteolysis by human deubiquitinating enzymes |
| Q27683623 | Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase |
| Q92724115 | Role of the COP9 Signalosome (CSN) in Cardiovascular Diseases |
| Q57934700 | Rpn11-mediated ubiquitin processing in an ancestral archaeal ubiquitination system |
| Q50296574 | STAMBPL1 is a deubiquitinase |
| Q35934305 | Selective and cell-active inhibitors of the USP1/ UAF1 deubiquitinase complex reverse cisplatin resistance in non-small cell lung cancer cells |
| Q38008504 | Selectivity of the ubiquitin-binding modules |
| Q33796008 | Specificity of the BRISC deubiquitinating enzyme is not due to selective binding to Lys63-linked polyubiquitin |
| Q27677566 | Stabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C-Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo Specificity |
| Q27671639 | Structural Basis for ESCRT-III CHMP3 Recruitment of AMSH |
| Q27653619 | Structural Basis for Recognition of Diubiquitins by NEMO |
| Q27683898 | Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease |
| Q93114616 | Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation |
| Q51016592 | Structural Insight into Ubiquitin-Like Protein Recognition and Oligomeric States of JAMM/MPN+ Proteases. |
| Q27672914 | Structural and Thermodynamic Comparison of the Catalytic Domain of AMSH and AMSH-LP: Nearly Identical Fold but Different Stability |
| Q28542494 | Structural and biochemical characterization of the Cop9 signalosome CSN5/CSN6 heterodimer |
| Q36932100 | Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle |
| Q24309375 | Structural basis and specificity of human otubain 1-mediated deubiquitination |
| Q36988986 | Structural basis for a reciprocal regulation between SCF and CSN. |
| Q47748414 | Structural basis for specific cleavage of Lys6-linked polyubiquitin chains by USP30. |
| Q27658279 | Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3 |
| Q27656035 | Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80 |
| Q35583928 | Structural basis for ubiquitin recognition by ubiquitin-binding zinc finger of FAAP20. |
| Q38081952 | Structural biology of the proteasome |
| Q46613519 | Structural biology: Corralling a protein-degradation regulator |
| Q37995728 | Structural insights into specificity and diversity in mechanisms of ubiquitin recognition by ubiquitin-binding domains |
| Q48251425 | Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168. |
| Q91972872 | Structural insights into ubiquitin recognition and Ufd1 interaction of Npl4 |
| Q35151712 | Structural regulation of cullin-RING ubiquitin ligase complexes |
| Q52322457 | Structure and Function of the 26S Proteasome. |
| Q27691353 | Structure characterization of the 26S proteasome |
| Q57262729 | Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4 |
| Q27681171 | Structure of the Human FANCL RING-Ube2T Complex Reveals Determinants of Cognate E3-E2 Selection |
| Q27688973 | Structure of the Rpn11-Rpn8 dimer reveals mechanisms of substrate deubiquitination during proteasomal degradation |
| Q47073950 | Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity. |
| Q26751372 | Substrate specificity of the ubiquitin and Ubl proteases |
| Q42264412 | Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity. |
| Q97418655 | Systematic analysis reveals a functional role for STAMBPL1 in the epithelial-mesenchymal transition process across multiple carcinomas |
| Q57801762 | TGF-β signaling pathway mediated by deubiquitinating enzymes |
| Q42314834 | Tandem UIMs confer Lys48 ubiquitin chain substrate preference to deubiquitinase USP25 |
| Q59830619 | Targeting Metalloenzymes for Therapeutic Intervention |
| Q33705575 | Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity |
| Q36660304 | The Colossus of ubiquitylation: decrypting a cellular code |
| Q30009488 | The ESCRT-III-interacting deubiquitinating enzyme AMSH3 is essential for degradation of ubiquitinated membrane proteins in Arabidopsis thaliana |
| Q87608311 | The JAMM in the proteasome |
| Q34155445 | The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments |
| Q24337075 | The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome |
| Q30009066 | The Vps27/Hrs/STAM (VHS) Domain of the Signal-transducing Adaptor Molecule (STAM) Directs Associated Molecule with the SH3 Domain of STAM (AMSH) Specificity to Longer Ubiquitin Chains and Dictates the Position of Cleavage |
| Q47111337 | The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1. |
| Q27679008 | The crystal structure of the MPN domain from the COP9 signalosome subunit CSN6 |
| Q40788674 | The deubiquitinating enzyme AMSH1 is required for rhizobial infection and nodule organogenesis in Lotus japonicus |
| Q43027496 | The deubiquitinating enzyme AMSH3 is required for intracellular trafficking and vacuole biogenesis in Arabidopsis thaliana |
| Q37517626 | The emerging role of deubiquitinating enzymes in genomic integrity, diseases, and therapeutics |
| Q38227721 | The emerging roles of deubiquitylating enzymes (DUBs) in the TGFβ and BMP pathways |
| Q40291384 | The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K. |
| Q33857612 | The regulation of TGF-β/SMAD signaling by protein deubiquitination |
| Q39008850 | The role of deubiquitinases in breast cancer. |
| Q27667316 | The structure of human ubiquitin in 2-methyl-2,4-pentanediol: A new conformational switch |
| Q24310748 | The translation initiation factor 3f (eIF3f) exhibits a deubiquitinase activity regulating Notch activation |
| Q34170749 | The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylation |
| Q36268060 | The ubiquitin-proteasome system of Saccharomyces cerevisiae |
| Q46325214 | Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases |
| Q54347722 | USP8 controls the trafficking and sorting of lysosomal enzymes. |
| Q48096070 | Ub-ProT reveals global length and composition of protein ubiquitylation in cells |
| Q40092833 | Ubiquitin Chains Modified by the Bacterial Ligase SdeA Are Protected from Deubiquitinase Hydrolysis |
| Q24310659 | Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis |
| Q30010083 | Ubiquitin and its binding domains. |
| Q28280440 | Ubiquitin chain conformation regulates recognition and activity of interacting proteins |
| Q38472387 | Ubiquitin fragments: their known biological activities and putative roles |
| Q37325110 | Ubiquitin in trafficking: the network at work |
| Q34539820 | Ubiquitin makes its mark on immune regulation |
| Q35641617 | Ubiquitin-Like Protein SAMP1 and JAMM/MPN+ Metalloprotease HvJAMM1 Constitute a System for Reversible Regulation of Metabolic Enzyme Activity in Archaea |
| Q29614829 | Ubiquitin-binding domains - from structures to functions |
| Q38175272 | Ubiquitin-dependent sorting in endocytosis |
| Q41889305 | Ubiquitin-interacting motifs confer full catalytic activity, but not ubiquitin chain substrate specificity, to deubiquitinating enzyme USP37. |
| Q38019556 | Ubiquitin-like modifiers |
| Q35579401 | Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization |
| Q36722909 | Unraveling the complexity of ubiquitin signaling |
| Q34774715 | Versatile roles of k63-linked ubiquitin chains in trafficking |
| Q109649533 | Zn‐Induced Interactions Between SARS‐CoV‐2 orf7a and BST2/Tetherin |
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