scholarly article | Q13442814 |
P50 | author | Ivan B Lomakin | Q64539061 |
P2093 | author name string | Thomas A Steitz | |
Ivan B Lomakin | |||
P2860 | cites work | An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs | Q22066003 |
Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes | Q24310392 | ||
Structure and interactions of the translation initiation factor eIF1 | Q24534133 | ||
PHENIX: a comprehensive Python-based system for macromolecular structure solution | Q24654617 | ||
The eIF1A solution structure reveals a large RNA-binding surface important for scanning function | Q27621444 | ||
The location of protein S8 and surrounding elements of 16S rRNA in the 70S ribosome from combined use of directed hydroxyl radical probing and X-ray crystallography | Q27622695 | ||
Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution | Q27627220 | ||
Crystal structure of an initiation factor bound to the 30S ribosomal subunit | Q27630228 | ||
Crystal structure of the ribosome at 5.5 A resolution | Q27630949 | ||
X-ray crystal structures of the WT and a hyper-accurate ribosome from Escherichia coli | Q27641657 | ||
Crystal structure of the eukaryotic 40S ribosomal subunit in complex with initiation factor 1 | Q27666453 | ||
The structure of the eukaryotic ribosome at 3.0 Å resolution | Q27675638 | ||
Structures of the human and Drosophila 80S ribosome | Q27684535 | ||
XDS | Q27860472 | ||
Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes | Q27860600 | ||
Structure of the 70S ribosome complexed with mRNA and tRNA | Q27860602 | ||
Overview of the CCP4 suite and current developments | Q27860782 | ||
A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon | Q27932344 | ||
The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome | Q27934357 | ||
A mechanistic overview of translation initiation in eukaryotes | Q28268066 | ||
Structural basis for the control of translation initiation during stress | Q28289449 | ||
Preparation and activity of synthetic unmodified mammalian tRNAi(Met) in initiation of translation in vitro | Q28362681 | ||
The mechanism of eukaryotic translation initiation and principles of its regulation | Q29547270 | ||
Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry | Q29614570 | ||
Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites | Q33333147 | ||
Regulatory elements in eIF1A control the fidelity of start codon selection by modulating tRNA(i)(Met) binding to the ribosome | Q33573600 | ||
Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing | Q33589752 | ||
The Cryo-EM structure of a complete 30S translation initiation complex from Escherichia coli | Q33959135 | ||
The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection | Q33962536 | ||
Molecular view of 43 S complex formation and start site selection in eukaryotic translation initiation | Q33967297 | ||
Specific functional interactions of nucleotides at key -3 and +4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complex | Q33993880 | ||
The eIF1A C-terminal domain promotes initiation complex assembly, scanning and AUG selection in vivo | Q34116876 | ||
Structural insights into eukaryotic ribosomes and the initiation of translation | Q34293825 | ||
The 30S ribosomal P site: a function of 16S rRNA. | Q34554616 | ||
Structure of the 30S translation initiation complex. | Q34596426 | ||
Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons | Q34752126 | ||
Molecular mechanism of scanning and start codon selection in eukaryotes | Q35192105 | ||
N- and C-terminal residues of eIF1A have opposing effects on the fidelity of start codon selection | Q35691356 | ||
Genetic identification of yeast 18S rRNA residues required for efficient recruitment of initiator tRNA(Met) and AUG selection | Q36843520 | ||
Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing. | Q37318477 | ||
Structure-function insights into prokaryotic and eukaryotic translation initiation. | Q37506795 | ||
How do eucaryotic ribosomes select initiation regions in messenger RNA? | Q37870587 | ||
Position of the CrPV IRES on the 40S subunit and factor dependence of IRES/80S ribosome assembly | Q40105027 | ||
Eukaryotic start and stop translation sites. | Q40504517 | ||
Kinetic and thermodynamic analysis of the role of start codon/anticodon base pairing during eukaryotic translation initiation | Q42003947 | ||
The fidelity of translation initiation: reciprocal activities of eIF1, IF3 and YciH. | Q42043465 | ||
Pi release from eIF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiation | Q46772123 | ||
Reconstitution of yeast translation initiation. | Q46968946 | ||
Communication between eukaryotic translation initiation factors 1 and 1A on the yeast small ribosomal subunit | Q47761220 | ||
Bulk-solvent correction in large macromolecular structures | Q57980824 | ||
P433 | issue | 7462 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 307-11 | |
P577 | publication date | 2013-08-15 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | The initiation of mammalian protein synthesis and mRNA scanning mechanism | |
P478 | volume | 500 |
Q42109595 | A bacterial homolog YciH of eukaryotic translation initiation factor eIF1 regulates stress-related gene expression and is unlikely to be involved in translation initiation fidelity. |
Q46103865 | A helicase-independent activity of eIF4A in promoting mRNA recruitment to the human ribosome |
Q24701801 | An RNA trapping mechanism in Alphavirus mRNA promotes ribosome stalling and translation initiation |
Q83226429 | An mRNA-binding channel in the ES6S region of the translation 48S-PIC promotes RNA unwinding and scanning |
Q93026270 | Androgen upregulates the palmitoylation of eIF3L in human prostate LNCaP cells |
Q48129458 | Catch me if you can: trapping scanning ribosomes in their footsteps |
Q36461919 | Chemical footprinting reveals conformational changes of 18S and 28S rRNAs at different steps of translation termination on the human ribosome |
Q58765724 | Comparative sequence and structure analysis of eIF1A and eIF1AD |
Q35948019 | Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex |
Q35131072 | Conformational changes in the P site and mRNA entry channel evoked by AUG recognition in yeast translation preinitiation complexes |
Q37631233 | Conserved residues in yeast initiator tRNA calibrate initiation accuracy by regulating preinitiation complex stability at the start codon |
Q92730638 | Control of Translation at the Initiation Phase During Glucose Starvation in Yeast |
Q109116643 | Coronavirus Nsp1: Immune Response Suppression and Protein Expression Inhibition |
Q89583429 | Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation |
Q30828138 | Cryo-EM study of start codon selection during archaeal translation initiation |
Q50875299 | Crystal Structure of the C-terminal Domain of Human eIF2D and Its Implications on Eukaryotic Translation Initiation. |
Q41341367 | Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1. |
Q91641936 | Crystal structure of the C-terminal domain of DENR |
Q90744821 | Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation |
Q55434885 | DENR-MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation. |
Q36914646 | DHX29 reduces leaky scanning through an upstream AUG codon regardless of its nucleotide context |
Q36426432 | Doubly Spin-Labeled RNA as an EPR Reporter for Studying Multicomponent Supramolecular Assemblies |
Q104439844 | Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation |
Q107111791 | Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation |
Q34534686 | Dynamics of ribosome scanning and recycling revealed by translation complex profiling. |
Q37491704 | Enhanced eIF1 binding to the 40S ribosome impedes conformational rearrangements of the preinitiation complex and elevates initiation accuracy. |
Q26771380 | Eukaryote-specific extensions in ribosomal proteins of the small subunit: Structure and function |
Q38764186 | Eukaryotic aspects of translation initiation brought into focus |
Q34115417 | Eukaryotic translation initiation factor eIF5 promotes the accuracy of start codon recognition by regulating Pi release and conformational transitions of the preinitiation complex |
Q36972906 | Heterogeneity of the translational machinery: Variations on a common theme. |
Q34509637 | Human eukaryotic initiation factor 2 (eIF2)-GTP-Met-tRNAi ternary complex and eIF3 stabilize the 43 S preinitiation complex |
Q59351754 | Interaction of rRNA with mRNA and tRNA in Translating Mammalian Ribosome: Functional Implications in Health and Disease |
Q38399151 | Interaction of tRNA with eukaryotic ribosome |
Q37662017 | Interface between 40S exit channel protein uS7/Rps5 and eIF2α modulates start codon recognition in vivo |
Q47857695 | Maternal Dead-end 1 promotes translation of nanos1 by binding the eIF3 complex. |
Q35636275 | Mechanism of cytoplasmic mRNA translation |
Q35961180 | Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors |
Q37739606 | Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5. |
Q39028088 | More than just scanning: the importance of cap-independent mRNA translation initiation for cellular stress response and cancer. |
Q102059631 | Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA |
Q34634172 | Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor β1-3 (TGF-β1-3). |
Q36046835 | Principles of start codon recognition in eukaryotic translation initiation |
Q35234645 | Quantitative analysis of mammalian translation initiation sites by FACS-seq |
Q28258346 | Quantitative studies of mRNA recruitment to the eukaryotic ribosome |
Q30856398 | Re-analysis of cryoEM data on HCV IRES bound to 40S subunit of human ribosome integrated with recent structural information suggests new contact regions between ribosomal proteins and HCV RNA |
Q42291024 | Recognition but no repair of abasic site in single-stranded DNA by human ribosomal uS3 protein residing within intact 40S subunit |
Q59125509 | Role of aIF1 in Pyrococcus abyssi translation initiation |
Q93340499 | Role of the uS9/yS16 C-terminal tail in translation initiation and elongation in Saccharomyces cerevisiae |
Q41750015 | Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons |
Q33983619 | Rps5-Rps16 communication is essential for efficient translation initiation in yeast S. cerevisiae |
Q100387950 | SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism |
Q64119701 | Start Codon Recognition in Eukaryotic and Archaeal Translation Initiation: A Common Structural Core |
Q38988322 | Stress-induced start codon fidelity regulates arsenite-inducible regulatory particle-associated protein (AIRAP) translation |
Q38459563 | Structural Insights into tRNA Dynamics on the Ribosome |
Q34440678 | Structural changes enable start codon recognition by the eukaryotic translation initiation complex |
Q27681329 | Structural integrity of the PCI domain of eIF3a/TIF32 is required for mRNA recruitment to the 43S pre-initiation complexes |
Q47384205 | Structural rearrangements in mRNA upon its binding to human 80S ribosomes revealed by EPR spectroscopy. |
Q49832547 | Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit. |
Q98944748 | Structure of a human 48S translational initiation complex |
Q27697933 | Structure of a yeast 40S-eIF1-eIF1A-eIF3-eIF3j initiation complex |
Q27694629 | Structure of the mammalian 80S initiation complex with initiation factor 5B on HCV-IRES RNA |
Q33778295 | Systematic genomic and translational efficiency studies of uveal melanoma |
Q51410878 | The Jigsaw Puzzle of mRNA Translation Initiation in Eukaryotes: A Decade of Structures Unraveling the Mechanics of the Process. |
Q38954583 | The integrated stress response. |
Q37565821 | The interaction between eukaryotic initiation factor 1A and eIF5 retains eIF1 within scanning preinitiation complexes |
Q38961838 | The molecular choreography of protein synthesis: translational control, regulation, and pathways |
Q36844633 | The ribosomal protein Asc1/RACK1 is required for efficient translation of short mRNAs |
Q35884199 | The β-hairpin of 40S exit channel protein Rps5/uS7 promotes efficient and accurate translation initiation in vivo. |
Q61804594 | Thomas A. Steitz (1940-2018) |
Q64942886 | Toward a Kinetic Understanding of Eukaryotic Translation. |
Q59327146 | Translating the Game: Ribosomes as Active Players |
Q52593667 | Translation and Translational Control in Dinoflagellates. |
Q36295149 | Translation complex profile sequencing to study the in vivo dynamics of mRNA-ribosome interactions during translation initiation, elongation and termination |
Q50055353 | Translation initiation of alphavirus mRNA reveals new insights into the topology of the 48S initiation complex. |
Q60048439 | Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition |
Q50420902 | Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression |
Q49294166 | Variants of the 5'-terminal region of p53 mRNA influence the ribosomal scanning and translation efficiency. |
Q42142778 | When Proteins Start to Make Sense: Fine-tuning Aminoglycosides for PTC Suppression Therapy |
Q26827587 | Why is start codon selection so precise in eukaryotes? |
Q61458334 | Z-DNA and Z-RNA in human disease |
Q46608158 | Zooming in on eukaryotic translation initiation |
Q52318693 | eIF1 Loop 2 interactions with Met-tRNAi control the accuracy of start codon selection by the scanning preinitiation complex. |
Q47252148 | eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast. |
Q37228876 | eIF1A/eIF5B interaction network and its functions in translation initiation complex assembly and remodeling |
Q34510080 | eIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning |
Q40385115 | microRNAs stimulate translation initiation mediated by HCV-like IRESes |
Search more.