The initiation of mammalian protein synthesis and mRNA scanning mechanism

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The initiation of mammalian protein synthesis and mRNA scanning mechanism is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1024717013
P356DOI10.1038/NATURE12355
P3181OpenCitations bibliographic resource ID2063448
P932PMC publication ID3748252
P698PubMed publication ID23873042
P5875ResearchGate publication ID250924165

P50authorIvan B LomakinQ64539061
P2093author name stringThomas A Steitz
Ivan B Lomakin
P2860cites workAn analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAsQ22066003
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Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomesQ27860600
Structure of the 70S ribosome complexed with mRNA and tRNAQ27860602
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A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codonQ27932344
The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosomeQ27934357
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Structural basis for the control of translation initiation during stressQ28289449
Preparation and activity of synthetic unmodified mammalian tRNAi(Met) in initiation of translation in vitroQ28362681
The mechanism of eukaryotic translation initiation and principles of its regulationQ29547270
Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entryQ29614570
Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sitesQ33333147
Regulatory elements in eIF1A control the fidelity of start codon selection by modulating tRNA(i)(Met) binding to the ribosomeQ33573600
Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probingQ33589752
The Cryo-EM structure of a complete 30S translation initiation complex from Escherichia coliQ33959135
The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selectionQ33962536
Molecular view of 43 S complex formation and start site selection in eukaryotic translation initiationQ33967297
Specific functional interactions of nucleotides at key -3 and +4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complexQ33993880
The eIF1A C-terminal domain promotes initiation complex assembly, scanning and AUG selection in vivoQ34116876
Structural insights into eukaryotic ribosomes and the initiation of translationQ34293825
The 30S ribosomal P site: a function of 16S rRNA.Q34554616
Structure of the 30S translation initiation complex.Q34596426
Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codonsQ34752126
Molecular mechanism of scanning and start codon selection in eukaryotesQ35192105
N- and C-terminal residues of eIF1A have opposing effects on the fidelity of start codon selectionQ35691356
Genetic identification of yeast 18S rRNA residues required for efficient recruitment of initiator tRNA(Met) and AUG selectionQ36843520
Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing.Q37318477
Structure-function insights into prokaryotic and eukaryotic translation initiation.Q37506795
How do eucaryotic ribosomes select initiation regions in messenger RNA?Q37870587
Position of the CrPV IRES on the 40S subunit and factor dependence of IRES/80S ribosome assemblyQ40105027
Eukaryotic start and stop translation sites.Q40504517
Kinetic and thermodynamic analysis of the role of start codon/anticodon base pairing during eukaryotic translation initiationQ42003947
The fidelity of translation initiation: reciprocal activities of eIF1, IF3 and YciH.Q42043465
Pi release from eIF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiationQ46772123
Reconstitution of yeast translation initiation.Q46968946
Communication between eukaryotic translation initiation factors 1 and 1A on the yeast small ribosomal subunitQ47761220
Bulk-solvent correction in large macromolecular structuresQ57980824
P433issue7462
P407language of work or nameEnglishQ1860
P304page(s)307-11
P577publication date2013-08-15
P1433published inNatureQ180445
P1476titleThe initiation of mammalian protein synthesis and mRNA scanning mechanism
P478volume500

Reverse relations

cites work (P2860)
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