| scholarly article | Q13442814 |
| P50 | author | Jean-Antoine Girault | Q33122764 |
| Stefan T. Arold | Q37376656 | ||
| Alvaro Ortega | Q43189317 | ||
| Nicolas Gervasi | Q56501492 | ||
| Karen Brami-Cherrier | Q56502479 | ||
| Bastien Seantier | Q79945184 | ||
| Katarzyna Walkiewicz | Q87264874 | ||
| P2093 | author name string | Marie-Claude Boutterin | |
| Diana Arsenieva | |||
| Paul G Leonard | |||
| Tahar Bouceba | |||
| Gress Kadaré | |||
| Laila Gasmi | |||
| P2860 | cites work | Integrin-regulated FAK-Src signaling in normal and cancer cells | Q24300271 |
| Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53 | Q24300771 | ||
| FAK promotes recruitment of talin to nascent adhesions to control cell motility | Q24303404 | ||
| Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation | Q24307387 | ||
| Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases | Q24336665 | ||
| pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions | Q24561464 | ||
| Cell signaling by receptor tyrosine kinases | Q24598357 | ||
| Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src | Q24614033 | ||
| Remediation of the protein data bank archive | Q24650571 | ||
| Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions | Q24651203 | ||
| Structural basis for the autoinhibition of focal adhesion kinase | Q24678318 | ||
| Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding | Q24681861 | ||
| Nudel and FAK as antagonizing strength modulators of nascent adhesions through paxillin | Q27330292 | ||
| The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases | Q27630908 | ||
| The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin | Q27637397 | ||
| Structural insight into the mechanisms of targeting and signaling of focal adhesion kinase | Q27638457 | ||
| The structural basis of localization and signaling by the focal adhesion targeting domain | Q27638962 | ||
| Molecular recognition of paxillin LD motifs by the focal adhesion targeting domain | Q27642274 | ||
| NMR solution structure of the focal adhesion targeting domain of focal adhesion kinase in complex with a paxillin LD peptide: evidence for a two-site binding model | Q27642755 | ||
| Structural basis for the interaction between focal adhesion kinase and CD4 | Q27649313 | ||
| Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2 | Q27654624 | ||
| Alternative splicing controls the mechanisms of FAK autophosphorylation | Q28118951 | ||
| Control of axonal branching and synapse formation by focal adhesion kinase | Q28587436 | ||
| Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis | Q28591107 | ||
| Focal adhesion kinase: the first ten years | Q28609173 | ||
| Environmental sensing through focal adhesions | Q29615211 | ||
| FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly | Q29616029 | ||
| Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice | Q29617498 | ||
| Crystal structure of the FERM domain of focal adhesion kinase. | Q30160113 | ||
| SH2- and SH3-mediated Interactions between Focal Adhesion Kinase and Src | Q30176302 | ||
| Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain | Q30194432 | ||
| Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin | Q30195270 | ||
| Direct interaction of focal adhesion kinase (FAK) with Met is required for FAK to promote hepatocyte growth factor-induced cell invasion | Q30445760 | ||
| FERM domain interaction promotes FAK signaling | Q30449206 | ||
| Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation. | Q30480350 | ||
| FAK phosphorylation at Tyr-925 regulates cross-talk between focal adhesion turnover and cell protrusion | Q30499286 | ||
| Organization and post-transcriptional processing of focal adhesion kinase gene | Q33252921 | ||
| The N-termini of FAK and JAKs contain divergent band 4.1 domains | Q33546886 | ||
| Role of kinase-independent and -dependent functions of FAK in endothelial cell survival and barrier function during embryonic development | Q33916059 | ||
| How focal adhesion kinase achieves regulation by linking ligand binding, localization and action | Q35597027 | ||
| VEGF-induced vascular permeability is mediated by FAK. | Q35697402 | ||
| The role of focal-adhesion kinase in cancer - a new therapeutic opportunity | Q36216076 | ||
| Focal adhesion kinase versus p53: apoptosis or survival? | Q37168898 | ||
| Signal transduction by focal adhesion kinase in cancer | Q37377635 | ||
| Autophosphorylation-independent and -dependent functions of focal adhesion kinase during development | Q37454238 | ||
| Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions | Q37717830 | ||
| Stretchy proteins on stretchy substrates: the important elements of integrin-mediated rigidity sensing | Q37779877 | ||
| The FERM domain: organizing the structure and function of FAK. | Q37802193 | ||
| Focal adhesion kinase: exploring Fak structure to gain insight into function | Q37863914 | ||
| Protein-tyrosine kinase CAKbeta/PYK2 is activated by binding Ca2+/calmodulin to FERM F2 alpha2 helix and thus forming its dimer | Q38296084 | ||
| Prediction of Hydrodynamic and Other Solution Properties of Rigid Proteins from Atomic- and Residue-Level Models | Q38492496 | ||
| Spatial and temporal regulation of focal adhesion kinase activity in living cells. | Q40060648 | ||
| Regulation of focal adhesion dynamics and disassembly by phosphorylation of FAK at tyrosine 397. | Q40373951 | ||
| A truncated FAK lacking the FERM domain displays high catalytic activity but retains responsiveness to adhesion-mediated signals | Q40394183 | ||
| Autophosphorylation of Tyr397 and its phosphorylation by Src-family kinases are altered in focal-adhesion-kinase neuronal isoforms | Q42134573 | ||
| Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2. | Q42242964 | ||
| A transmembrane-anchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to pp125FAK. | Q42496206 | ||
| Direct transmembrane clustering and cytoplasmic dimerization of focal adhesion kinase initiates its tyrosine phosphorylation | Q42809412 | ||
| Dynamic conformational changes in the FERM domain of FAK are involved in focal-adhesion behavior during cell spreading and motility. | Q46125886 | ||
| Focal Adhesion Kinase in Rat Central Nervous System | Q58191988 | ||
| Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors | Q72347547 | ||
| Nuclear localization and apoptotic regulation of an amino-terminal domain focal adhesion kinase fragment in endothelial cells | Q73067283 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 356-370 | |
| P577 | publication date | 2014-02-18 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | FAK dimerization controls its kinase-dependent functions at focal adhesions | |
| P478 | volume | 33 |
| Q39147472 | Addressing the Functional Determinants of FAK during Ciliogenesis in Multiciliated Cells. |
| Q26765154 | Adhesion protein networks reveal functions proximal and distal to cell-matrix contacts |
| Q30368603 | Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells. |
| Q36361852 | DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons |
| Q54976490 | Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development. |
| Q90122397 | Extracellular signal regulated kinase 5 promotes cell migration, invasion and lung metastasis in a FAK-dependent manner |
| Q93000114 | FAK Structure and Regulation by Membrane Interactions and Force in Focal Adhesions |
| Q27026533 | FAK in cancer: mechanistic findings and clinical applications |
| Q36244298 | Focal Adhesion Kinase: Insight into Molecular Roles and Functions in Hepatocellular Carcinoma |
| Q39141363 | Focal adhesion kinase signaling in unexpected places |
| Q64271364 | High resolution crystal structure of the FAK FERM domain reveals new insights on the Druggability of tyrosine 397 and the Src SH3 binding site |
| Q38215562 | How to find a leucine in a haystack? Structure, ligand recognition and regulation of leucine-aspartic acid (LD) motifs |
| Q33794378 | Integrin α2β1 in nonactivated conformation can induce focal adhesion kinase signaling |
| Q38358692 | Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin |
| Q40045183 | Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading. |
| Q45318121 | MET activates PTK2 signaling |
| Q28550745 | Mechanism of Focal Adhesion Kinase Mechanosensing |
| Q36539304 | Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition. |
| Q33724031 | Molecular and cellular impact of Psoriasin (S100A7) on the healing of human wounds. |
| Q38604713 | New Treatment Opportunities in Phosphatase and Tensin Homolog (PTEN)-Deficient Tumors: Focus on PTEN/Focal Adhesion Kinase Pathway |
| Q35255826 | New insights into FAK phosphorylation based on a FAT domain-defective mutation |
| Q92310282 | PROTACs: great opportunities for academia and industry |
| Q50298114 | PTK2 autophosphorylates |
| Q27684765 | Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes |
| Q36286471 | Phospholipid binding to the FAK catalytic domain impacts function. |
| Q90317373 | Proteome-wide Tyrosine Phosphorylation Analysis Reveals Dysregulated Signaling Pathways in Ovarian Tumors |
| Q56531947 | Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation |
| Q47984078 | Regulation of Focal Adhesion Kinase through a Direct Interaction with an Endogenous Inhibitor. |
| Q90663402 | Small molecule FAK activator promotes human intestinal epithelial monolayer wound closure and mouse ulcer healing |
| Q58726403 | Targeting Focal Adhesion Kinase Using Inhibitors of Protein-Protein Interactions |
| Q58712101 | The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer |
| Q39274304 | The Janus Kinase (JAK) FERM and SH2 Domains: Bringing Specificity to JAK-Receptor Interactions |
| Q38255120 | The diverse roles and multiple forms of focal adhesion kinase in brain. |
| Q30357240 | The mTOR-FAK mechanotransduction signaling axis for focal adhesion maturation and cell proliferation. |
| Q64988659 | The roles of nuclear focal adhesion kinase (FAK) on Cancer: a focused review. |
| Q35009792 | Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights |
| Q39241548 | β-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4. |
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