Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes

scientific article

Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1107/S0907444913011220
P698PubMed publication ID23897481

P50authorBonsu KuQ57034723
Jae U. JungQ13452350
P2093author name stringByung-Ha Oh
Young Kwan Kim
Jooyoung Lee
Keehyoung Joo
Mi-Jeong Kwak
Hye-Young Suh
P2860cites workCrystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligaseQ34650624
Structural assembly of cullin-RING ubiquitin ligase complexesQ34762436
The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat familiesQ35211894
Flexible Cullins in Cullin-RING E3 Ligases Allosterically Regulate UbiquitinationQ35562631
The Role of Elongin BC-Containing Ubiquitin LigasesQ35971082
The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppressionQ37289267
Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligasesQ40026609
Dissection of the HIV Vif interaction with human E3 ubiquitin ligaseQ41963681
Cullin-RING ubiquitin ligases: global regulation and activation cyclesQ21203558
Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor functionQ22009393
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activityQ22009487
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complexQ24294734
Twenty proteins containing a C-terminal SOCS box form five structural classesQ24317684
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligasesQ24322407
CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complexQ24336508
Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligaseQ24336527
Inhibition of Transcription Elongation by the VHL Tumor Suppressor ProteinQ24336629
Crystallography & NMR System: A New Software Suite for Macromolecular Structure DeterminationQ26778405
Structure of the SOCS4-ElonginB/C Complex Reveals a Distinct SOCS Box Interface and the Molecular Basis for SOCS-Dependent EGFR DegradationQ27649020
The SOCS Box Domain of SOCS3: Structure and Interaction with the ElonginBC-Cullin5 Ubiquitin LigaseQ27651007
All-atom empirical potential for molecular modeling and dynamics studies of proteinsQ27860468
Molecular replacement with MOLREPQ27860539
Mechanisms underlying ubiquitinationQ27860656
Overview of the CCP4 suite and current developmentsQ27860782
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-boxQ27936367
Function and regulation of cullin-RING ubiquitin ligasesQ28131707
Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alphaQ28143121
The SOCS box: a tale of destruction and degradationQ28205975
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligaseQ28506124
An efficient newton-like method for molecular mechanics energy minimization of large moleculesQ29543705
The ubiquitin system for protein degradationQ29614385
Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligasesQ34252986
P433issuePt 8
P304page(s)1587-1597
P577publication date2013-07-20
P1433published inActa Crystallographica Section D: Biological CrystallographyQ1933255
P1476titleStructural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes
P478volume69

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cites work (P2860)
Q35080292Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).
Q39181425CBFß and HIV Infection.
Q38380126Cell regulation by phosphotyrosine-targeted ubiquitin ligases
Q38673650Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex
Q40303257Cullin-RING E3 Ubiquitin Ligases: Bridges to Destruction.
Q47269109Identification of a conserved interface of HIV-1 and FIV Vifs with Cullin 5.
Q35152151Insights into Cullin-RING E3 ubiquitin ligase recruitment: structure of the VHL-EloBC-Cul2 complex
Q35677393Serendipitous SAD Solution for DMSO-Soaked SOCS2-ElonginC-ElonginB Crystals Using Covalently Incorporated Dimethylarsenic: Insights into Substrate Receptor Conformational Flexibility in Cullin RING Ligases.
Q42152378Structural basis for hijacking CBF-β and CUL5 E3 ligase complex by HIV-1 Vif.
Q38522152Structural basis of Keap1 interactions with Nrf2.
Q64935699Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase.
Q90093309Structural perspectives on HIV-1 Vif and APOBEC3 restriction factor interactions
Q96230331Structure and dynamics of the ASB9 CUL-RING E3 Ligase
Q34043797Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation
Q54115189The molecular basis of JAK/STAT inhibition by SOCS1.

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