Cul8/Rtt101 forms a variety of protein complexes that regulate DNA damage response and transcriptional silencing

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Cul8/Rtt101 forms a variety of protein complexes that regulate DNA damage response and transcriptional silencing is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109.082107
P3181OpenCitations bibliographic resource ID4638632
P932PMC publication ID2843234
P698PubMed publication ID20139071

P2093author name stringTsuyoshi Yamaguchi
Chikashi Obuse
Takumi Kamura
Emiko Noro
Satoru Ishii
Satoru Mimura
Tomoya Katsura
P2860cites workA conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1Q24308736
Sir2 deacetylates histone H3 lysine 56 to regulate telomeric heterochromatin structure in yeast.Q36102455
Regulation of rtt107 recruitment to stalled DNA replication forks by the cullin rtt101 and the rtt109 acetyltransferaseQ36325888
Histone H3 lysine 56 acetylation: a new twist in the chromosome cycleQ36685745
HST3/HST4-dependent deacetylation of lysine 56 of histone H3 in silent chromatinQ36954157
The Saccharomyces cerevisiae Esc2 and Smc5-6 proteins promote sister chromatid junction-mediated intra-S repairQ37127298
Origin recognition complex (ORC) in transcriptional silencing and DNA replication in S. cerevisiaeQ46889661
Ubiquitin ligase component Cul4 associates with Clr4 histone methyltransferase to assemble heterochromatin.Q53659537
The Cullin Rtt101p Promotes Replication Fork Progression through Damaged DNA and Natural Pause SitesQ63965584
Chl1 and Ctf4 are required for damage-induced recombinationsQ79556509
The amino-terminal TPR domain of Dia2 tethers SCF(Dia2) to the replisome progression complexQ84901617
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligasesQ24322407
A refined two-hybrid system reveals that SCF(Cdc4)-dependent degradation of Swi5 contributes to the regulatory mechanism of S-phase entryQ24652757
Mms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase IIQ24791392
Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) familyQ24806914
Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockageQ27930463
Esc4/Rtt107 and the control of recombination during replicationQ27931246
A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progressionQ27931729
Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8.Q27932665
Saccharomyces cerevisiae CTF18 and CTF4 are required for sister chromatid cohesionQ27933988
ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cellsQ27934208
GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forksQ27934889
Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenanceQ27935789
The SCFCdc4 ubiquitin ligase regulates calcineurin signaling through degradation of phosphorylated Rcn1, an inhibitor of calcineurinQ27935806
SCF(Dia2) regulates DNA replication forks during S-phase in budding yeastQ27936357
Evidence that POB1, a Saccharomyces cerevisiae protein that binds to DNA polymerase alpha, acts in DNA metabolism in vivoQ27936854
Esc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae.Q27937523
MGA2 and SPT23 are modifiers of transcriptional silencing in yeastQ27937810
A SUMO-like domain protein, Esc2, is required for genome integrity and sister chromatid cohesion in Saccharomyces cerevisiae.Q27938418
Establishment of sister chromatid cohesion at the S. cerevisiae replication forkQ27939134
Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNAQ27939872
DNA replication in eukaryotic cellsQ28131747
The SCF ubiquitin ligase: insights into a molecular machineQ28279993
Interactions between BRCT repeats and phosphoproteins: tangled up in twoQ28289371
A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kinQ29618006
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction mapQ29618911
A DNA integrity network in the yeast Saccharomyces cerevisiaeQ29618912
One-hybrid screens at the Saccharomyces cerevisiae HMR locus identify novel transcriptional silencing factorsQ33199507
The origin recognition complex links replication, sister chromatid cohesion and transcriptional silencing in Saccharomyces cerevisiaeQ34645049
Mms22 preserves genomic integrity during DNA replication in Schizosaccharomyces pombeQ36052321
P433issue13
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
DNA damageQ5205747
Cul8-RING ubiquitin ligase complexQ22326809
Esc2p YDR363WQ27549285
Rtt107p YHR154WQ27549560
Mms1p YPR164WQ27549945
Chromatin-binding protein CTF4 YPR135WQ27550454
Origin recognition complex subunit 5 YNL261WQ27550489
Cullin RTT101 YJL047CQ27551689
Mms22p YLR320WQ27552097
DNA-binding SCF ubiquitin ligase subunit DIA2 YOR080WQ27553151
P304page(s)9858-67
P577publication date2010-03-26
P1433published inJournal of Biological ChemistryQ867727
P1476titleCul8/Rtt101 forms a variety of protein complexes that regulate DNA damage response and transcriptional silencing
P478volume285

Reverse relations

cites work (P2860)
Q36662986Chromatin structure in telomere dynamics
Q36775512Chromosome-wide histone deacetylation by sirtuins prevents hyperactivation of DNA damage-induced signaling upon replicative stress
Q38736165Constructing module maps for integrated analysis of heterogeneous biological networks
Q39616391Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase
Q42127466Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome
Q35679278Heterochromatin formation via recruitment of DNA repair proteins.
Q26778138Linking replication stress with heterochromatin formation
Q42133200Mms1 and Mms22 stabilize the replisome during replication stress
Q38942428Multi-BRCT scaffolds use distinct strategies to support genome maintenance.
Q102053779Mus81-Mms4 endonuclease is an Esc2-STUbL-Cullin8 mitotic substrate impacting on genome integrity
Q38577430Navigating yeast genome maintenance with functional genomics
Q24309443RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells
Q35342649Replisome function during replicative stress is modulated by histone h3 lysine 56 acetylation through Ctf4.
Q36172725Rtt107 Is a Multi-functional Scaffold Supporting Replication Progression with Partner SUMO and Ubiquitin Ligases
Q36588976Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork
Q36073403Shaping the landscape: mechanistic consequences of ubiquitin modification of chromatin.
Q34530058Supervised maximum-likelihood weighting of composite protein networks for complex prediction.
Q24306030The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination
Q35916165The Replisome-Coupled E3 Ubiquitin Ligase Rtt101Mms22 Counteracts Mrc1 Function to Tolerate Genotoxic Stress
Q37289716The Rtt107 BRCT scaffold and its partner modification enzymes collaborate to promote replication.
Q27931052The SCFDia2 ubiquitin E3 ligase ubiquitylates Sir4 and functions in transcriptional silencing