L-proline accumulation and freeze tolerance of Saccharomyces cerevisiae are caused by a mutation in the PRO1 gene encoding gamma-glutamyl kinase

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L-proline accumulation and freeze tolerance of Saccharomyces cerevisiae are caused by a mutation in the PRO1 gene encoding gamma-glutamyl kinase is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AEM.69.1.212-219.2003
P932PMC publication ID152471
P698PubMed publication ID12513997

P2093author name stringHiroshi Takagi
Yuko Morita
Shigeru Nakamori
P2860cites workPhysiological and genetic responses of bacteria to osmotic stressQ24594026
Gene-enzyme relationships in the proline biosynthetic pathway of Saccharomyces cerevisiaeQ27931568
Genetics and physiology of proline utilization in Saccharomyces cerevisiae: enzyme induction by prolineQ27932500
Proline biosynthesis in Saccharomyces cerevisiae: molecular analysis of the PRO1 gene, which encodes gamma-glutamyl kinaseQ27940209
Molecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibitionQ28114960
Cloning human pyrroline-5-carboxylate reductase cDNA by complementation in Saccharomyces cerevisiaeQ28117960
Two differentially regulated mRNAs with different 5' ends encode secreted with intracellular forms of yeast invertaseQ28131607
Cloning genes by complementation in yeastQ29620931
Saccharomyces cerevisiae sigma 1278b has novel genes of the N-acetyltransferase gene superfamily required for L-proline analogue resistanceQ31786182
A soybean gene encoding delta 1-pyrroline-5-carboxylate reductase was isolated by functional complementation in Escherichia coli and is found to be osmoregulatedQ34048055
Removal of feedback inhibition of delta(1)-pyrroline-5-carboxylate synthetase results in increased proline accumulation and protection of plants from osmotic stress.Q34508098
Proline biosynthesis in Saccharomyces cerevisiae: analysis of the PRO3 gene, which encodes delta 1-pyrroline-5-carboxylate reductaseQ36112214
Proline inhibits aggregation during protein refoldingQ36281879
Purification and characteristics of a gamma-glutamyl kinase involved in Escherichia coli proline biosynthesisQ36297472
Proline transport in Saccharomyces cerevisiae.Q36308370
Proline utilization in Saccharomyces cerevisiae: analysis of the cloned PUT1 geneQ36463512
Correlation between the induction of a gene for delta 1-pyrroline-5-carboxylate synthetase and the accumulation of proline in Arabidopsis thaliana under osmotic stress.Q36706696
A bifunctional enzyme (delta 1-pyrroline-5-carboxylate synthetase) catalyzes the first two steps in proline biosynthesis in plantsQ37234456
Overexpression of [delta]-Pyrroline-5-Carboxylate Synthetase Increases Proline Production and Confers Osmotolerance in Transgenic PlantsQ39139212
Overproduction of L-cysteine and L-cystine by Escherichia coli strains with a genetically altered serine acetyltransferaseQ39560513
Construction of a proline-producing mutant of the extremely thermophilic eubacterium Thermus thermophilus HB27.Q39562928
A single base pair change in proline biosynthesis genes causes osmotic stress toleranceQ39955313
Proline-hyperproducing strains of Serratia marcescens: enhancement of proline analog-mediated growth inhibition by increasing osmotic stressQ40050151
Selection of yeasts for breadmaking by the frozen-dough methodQ40054683
A novel acetyltransferase found in Saccharomyces cerevisiae Sigma1278b that detoxifies a proline analogue, azetidine-2-carboxylic acidQ43736462
Subcellular location of delta-pyrroline-5-carboxylate reductase in root/nodule and leaf of soybeanQ47916118
Analysis of the mutant proBA operon from a proline-producing strain of Serratia marcescensQ48180128
Analysis of the Serratia marcescens proBA operon and feedback control of proline biosynthesisQ48234003
Membrane stabilization during freezing: the role of two natural cryoprotectants, trehalose and prolineQ49305798
Proline over-production results in enhanced osmotolerance in Salmonella typhimuriumQ50217692
Proline accumulation by mutation or disruption of the proline oxidase gene improves resistance to freezing and desiccation stresses in Saccharomyces cerevisiae.Q52538157
Removal of Feedback Inhibition of Δ1-Pyrroline-5-carboxylate Synthetase, a Bifunctional Enzyme Catalyzing the First Two Steps of Proline Biosynthesis in PlantsQ54605192
The Escherichia coli proB gene corrects the proline auxotrophy of Saccharomyces cerevisiae pro1 mutantsQ57577958
Nucleotide sequence of a mutation in the proB gene of Escherichia coli that confers proline overproduction and enhanced tolerance to osmotic stressQ69834143
The Gene-Enzyme Relationships of Proline Biosynthesis in Escherichia coliQ72872646
Isolation of freeze-tolerant laboratory strains of Saccharomyces cerevisiae from proline-analogue-resistant mutantsQ73367963
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmicrobiologyQ7193
biotechnologyQ7108
Saccharomyces cerevisiaeQ719725
food scienceQ1637030
L-prolineQ20035886
Glutamate-5-semialdehyde dehydrogenase YOR323CQ27547134
Glutamate 5-kinase YDR300CQ27549941
freeze toleranceQ125958673
P304page(s)212-9
P577publication date2003-01-01
P1433published inApplied and Environmental MicrobiologyQ4781593
P1476titleL-proline accumulation and freeze tolerance of Saccharomyces cerevisiae are caused by a mutation in the PRO1 gene encoding gamma-glutamyl kinase
P478volume69

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cites work (P2860)
Q33193077A nonconserved Ala401 in the yeast Rsp5 ubiquitin ligase is involved in degradation of Gap1 permease and stress-induced abnormal proteins
Q36981750A simplified model of local structure in aqueous proline amino acid revealed by first-principles molecular dynamics simulations
Q37404904Cryotolerance strategies of Pseudomonads isolated from the rhizosphere of Himalayan plants
Q42121844Desensitization of feedback inhibition of the Saccharomyces cerevisiae gamma-glutamyl kinase enhances proline accumulation and freezing tolerance
Q34232570Effect of L-proline on sake brewing and ethanol stress in Saccharomyces cerevisiae
Q38264852Evolution of proline biosynthesis: enzymology, bioinformatics, genetics, and transcriptional regulation.
Q42316612Exogenous addition of histidine reduces copper availability in the yeast Saccharomyces cerevisiae
Q40172064Gene Dosage Effect of l -Proline Biosynthetic Enzymes on l -Proline Accumulation and Freeze Tolerance in Saccharomyces cerevisiae
Q37410132Insufficiency of copper ion homeostasis causes freeze-thaw injury of yeast cells as revealed by indirect gene expression analysis
Q28296443Molecular Mechanisms Modulating Glutamate Kinase Activity. Identification of the Proline Feedback Inhibitor Binding Site
Q36159049Nitric oxide signaling in yeast
Q34353959Oxygen reactivity of PutA from Helicobacter species and proline-linked oxidative stress
Q28757069Progress in metabolic engineering of Saccharomyces cerevisiae
Q46601957Proline accumulation protects Saccharomyces cerevisiae cells in stationary phase from ethanol stress by reducing reactive oxygen species levels
Q37033593Proline dehydrogenase regulates redox state and respiratory metabolism in Trypanosoma cruzi
Q34853615Proline metabolism increases katG expression and oxidative stress resistance in Escherichia coli
Q36497122Proline modulates the intracellular redox environment and protects mammalian cells against oxidative stress
Q38115478Properties, metabolisms, and applications of (L)-proline analogues
Q34094046Pyrroline-5-carboxylate synthase and proline biosynthesis: from osmotolerance to rare metabolic disease
Q37494103Role of the yeast acetyltransferase Mpr1 in oxidative stress: regulation of oxygen reactive species caused by a toxic proline catabolism intermediate
Q38313119Rsp5 regulates expression of stress proteins via post-translational modification of Hsf1 and Msn4 in Saccharomyces cerevisiae
Q36899099Self-cloning baker's yeasts that accumulate proline enhance freeze tolerance in doughs
Q37498896Stress-tolerance of baker's-yeast (Saccharomyces cerevisiae) cells: stress-protective molecules and genes involved in stress tolerance
Q34720799Tomato QM-like protein protects Saccharomyces cerevisiae cells against oxidative stress by regulating intracellular proline levels
Q27929899Uptake of inorganic phosphate is a limiting factor for Saccharomyces cerevisiae during growth at low temperatures

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