| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/PRO.340 |
| P8608 | Fatcat ID | release_74e327rzireodla2umrlxswboq |
| P932 | PMC publication ID | 2866264 |
| P698 | PubMed publication ID | 20091669 |
| P5875 | ResearchGate publication ID | 41103984 |
| P50 | author | Jesus Rodriguez-Diaz | Q61858383 |
| P2093 | author name string | Javier Cervera | |
| Ana I Martínez | |||
| Isabel Pérez-Arellano | |||
| Francisco Carmona-Alvarez | |||
| P2860 | cites work | Hyperammonemia with reduced ornithine, citrulline, arginine and proline: a new inborn error caused by a mutation in the gene encoding delta(1)-pyrroline-5-carboxylate synthase | Q24290552 |
| Mutations in PYCR1 cause cutis laxa with progeroid features | Q24319369 | ||
| Overexpression of [delta]-Pyrroline-5-Carboxylate Synthetase Increases Proline Production and Confers Osmotolerance in Transgenic Plants | Q39139212 | ||
| Duplicated P5CS genes of Arabidopsis play distinct roles in stress regulation and developmental control of proline biosynthesis. | Q39503146 | ||
| The evolution of pyrroline-5-carboxylate synthase in plants: a key enzyme in proline synthesis | Q39538161 | ||
| Construction of a Proline-Producing Mutant of the Extremely Thermophilic Eubacterium Thermus thermophilus HB27 | Q39562928 | ||
| Proline and glycinebetaine confer cadmium tolerance on tobacco bright yellow-2 cells by increasing ascorbate-glutathione cycle enzyme activities | Q39790610 | ||
| Activation of glutamate by gamma-glutamate kinase: formation of gamma-cis-cycloglutamyl phosphate, an analog of gamma-glutamyl phosphate | Q41276502 | ||
| Salinity-dependent switching of osmolyte strategies in a moderately halophilic bacterium: glutamate induces proline biosynthesis in Halobacillus halophilus | Q42072811 | ||
| Basis of arginine sensitivity of microbial N-acetyl-L-glutamate kinases: mutagenesis and protein engineering study with the Pseudomonas aeruginosa and Escherichia coli enzymes | Q42126914 | ||
| Salt stress increases the expression of p5cs gene and induces proline accumulation in cactus pear | Q42638581 | ||
| Identification of a mutation that relieves gamma-glutamyl kinase from allosteric feedback inhibition by proline | Q44101009 | ||
| Molecular mechanisms of proline-mediated tolerance to toxic heavy metals in transgenic microalgae | Q44205943 | ||
| Identification of regions of the tomato gamma-glutamyl kinase that are involved in allosteric regulation by proline | Q44302117 | ||
| Transgenic tobacco plants accumulating osmolytes show reduced oxidative damage under freezing stress | Q44827744 | ||
| The role of [Delta]1-pyrroline-5-carboxylate dehydrogenase in proline degradation | Q45153601 | ||
| Proline accumulation and transcriptional regulation of proline biosynthesis and degradation in Brassica napus | Q46134018 | ||
| A missense mutation in ALDH18A1, encoding Delta1-pyrroline-5-carboxylate synthase (P5CS), causes an autosomal recessive neurocutaneous syndrome. | Q46597596 | ||
| Dissection of Escherichia coli glutamate 5-kinase: functional impact of the deletion of the PUA domain | Q46842175 | ||
| Metabolic changes associated with adaptation of plant cells to water stress | Q47928894 | ||
| Effect of water stress on proline synthesis from radioactive precursors | Q47941654 | ||
| Proline accumulation in developing grapevine fruit occurs independently of changes in the levels of delta1-pyrroline-5-carboxylate synthetase mRNA or protein | Q47949254 | ||
| Analysis of the mutant proBA operon from a proline-producing strain of Serratia marcescens | Q48180128 | ||
| Proline over-production results in enhanced osmotolerance in Salmonella typhimurium | Q50217692 | ||
| Comparative Analysis of the Regulation of Expression and Structures of Two Evolutionarily Divergent Genes for Δ1-Pyrroline-5-Carboxylate Synthetase from Tomato | Q52183520 | ||
| Proline biosynthesis in Escherichia coli kinetic and mechanistic properties of glutamate semialdehyde dehydrogenase | Q52709087 | ||
| Mapping active site residues in glutamate-5-kinase. The substrate glutamate and the feed-back inhibitor proline bind at overlapping sites | Q54452911 | ||
| Removal of Feedback Inhibition of Δ1-Pyrroline-5-carboxylate Synthetase, a Bifunctional Enzyme Catalyzing the First Two Steps of Proline Biosynthesis in Plants | Q54605192 | ||
| Nucleotide sequence of a mutation in the proB gene of Escherichia coli that confers proline overproduction and enhanced tolerance to osmotic stress | Q69834143 | ||
| Proline accumulates in plants exposed to UV radiation and protects them against UV induced peroxidation | Q72182058 | ||
| Pyrroline-5-carboxylate synthesis from glutamate by rat intestinal mucosa | Q72548385 | ||
| The Gene-Enzyme Relationships of Proline Biosynthesis in Escherichia coli | Q72872646 | ||
| The interconversion of glutamic acid and proline. I. The formation of delta1-pyrroline-5-carboxylic acid from glutamic acid in Escherichia coli | Q74456036 | ||
| Glutamate kinase as a potential biomarker of heavy metal stress in plants | Q80984046 | ||
| Solute Accumulation in Tobacco Cells Adapted to NaCl | Q83265676 | ||
| Solubilization of a Proline Dehydrogenase from Maize (Zea mays L.) Mitochondria | Q83271175 | ||
| The Distribution of Free Amino Acids, Especially of Proline, in the Organs of Field Bean Plants, Vicia faba L., during Development in the Field | Q85570857 | ||
| Human brain-specific L-proline transporter: molecular cloning, functional expression, and chromosomal localization of the gene in human and mouse genomes | Q24329056 | ||
| Structure of acetylglutamate kinase, a key enzyme for arginine biosynthesis and a prototype for the amino acid kinase enzyme family, during catalysis | Q27638963 | ||
| Crystal structure of gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 A resolution | Q27642894 | ||
| A novel two-domain architecture within the amino acid kinase enzyme family revealed by the crystal structure of Escherichia coli glutamate 5-kinase | Q27643896 | ||
| The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold | Q27735518 | ||
| The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling | Q27860637 | ||
| L-proline accumulation and freeze tolerance of Saccharomyces cerevisiae are caused by a mutation in the PRO1 gene encoding gamma-glutamyl kinase | Q27935456 | ||
| Novel predicted RNA-binding domains associated with the translation machinery | Q27939664 | ||
| Molecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition | Q28114960 | ||
| Proline synthesis in Escherichia coli a proline-inhibitable glutamic acid kinase | Q28247495 | ||
| Human Delta1-pyrroline-5-carboxylate synthase: function and regulation | Q28275915 | ||
| The metabolism of proline, a stress substrate, modulates carcinogenic pathways | Q28275923 | ||
| Delta1-pyrroline-5-carboxylate synthase deficiency: neurodegeneration, cataracts and connective tissue manifestations combined with hyperammonaemia and reduced ornithine, citrulline, arginine and proline | Q28290796 | ||
| Assignment of the human gene encoding the delta 1-pyrroline-5-carboxylate synthetase (P5CS) to 10q24.3 by in situ hybridization | Q28296857 | ||
| Glutamate-related gene expression changes with age in the mouse auditory midbrain | Q30494225 | ||
| A genetic investigation of the essential role of glutathione: mutations in the proline biosynthesis pathway are the only suppressors of glutathione auxotrophy in yeast | Q30964979 | ||
| Isolation and characterization of two different cDNAs of delta1-pyrroline-5-carboxylate synthase in alfalfa, transcriptionally induced upon salt stress. | Q31949161 | ||
| Directed evolution of an artificial bifunctional enzyme, gamma-glutamyl kinase/gamma-glutamyl phosphate reductase, for improved osmotic tolerance of Escherichia coli transformants | Q33256731 | ||
| The proline biosynthetic genes P5CS1 and P5CS2 play overlapping roles in Arabidopsis flower transition but not in embryo development | Q33347456 | ||
| Mutations in the listerial proB gene leading to proline overproduction: effects on salt tolerance and murine infection | Q33990438 | ||
| Proline accumulation in plants: a review. | Q34766352 | ||
| Arginine nutrition in neonatal pigs | Q35909710 | ||
| Pyrroline-5-carboxylate synthase activity in mammalian cells | Q36405530 | ||
| Proline modulates the intracellular redox environment and protects mammalian cells against oxidative stress | Q36497122 | ||
| Correlation between the induction of a gene for delta 1-pyrroline-5-carboxylate synthetase and the accumulation of proline in Arabidopsis thaliana under osmotic stress. | Q36706696 | ||
| Self-cloning baker's yeasts that accumulate proline enhance freeze tolerance in doughs | Q36899099 | ||
| The PUA domain - a structural and functional overview | Q36931009 | ||
| A bifunctional enzyme (delta 1-pyrroline-5-carboxylate synthetase) catalyzes the first two steps in proline biosynthesis in plants | Q37234456 | ||
| Mutation in pyrroline-5-carboxylate reductase 1 gene in families with cutis laxa type 2 | Q37253438 | ||
| Functional genomics and SNP analysis of human genes encoding proline metabolic enzymes | Q37255176 | ||
| Proline antagonizes GABA-induced quenching of quorum-sensing in Agrobacterium tumefaciens | Q37321144 | ||
| Isolation, characterization, and chromosomal location of a gene encoding the delta 1-pyrroline-5-carboxylate synthetase in Arabidopsis thaliana | Q38291416 | ||
| Expression of Bacillus subtilis proBA genes and reduction of feedback inhibition of proline synthesis increases proline production and confers osmotolerance in transgenic Arabidopsis | Q38942016 | ||
| P433 | issue | 3 | |
| P921 | main subject | metabolic disease | Q2351083 |
| P304 | page(s) | 372-382 | |
| P577 | publication date | 2010-03-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Protein Science | Q7251445 |
| P1476 | title | Pyrroline-5-carboxylate synthase and proline biosynthesis: from osmotolerance to rare metabolic disease | |
| P478 | volume | 19 |
| Q50905329 | Characterization of γ-glutamyl kinase mutants from Saccharomyces cerevisiae |
| Q47110970 | Creating Oxidase-Peroxidase Fusion Enzymes as a Toolbox for Cascade Reactions. |
| Q57897891 | Extreme climatic events: impacts of drought and high temperature on physiological processes in agronomically important plants |
| Q58795415 | Family-Four Aldehyde Dehydrogenases Play an Indispensable Role in the Pathogenesis of |
| Q42751993 | Gene expression profiling of microbial activities and interactions in sediments under haloclines of E. Mediterranean deep hypersaline anoxic basins. |
| Q48159829 | Genome Mining and Assembly-Line Biosynthesis of the UCS1025A Pyrrolizidinone Family of Fungal Alkaloids. |
| Q52718926 | Halotolerant Exiguobacterium profundum PHM11 Tolerate Salinity by Accumulating L-Proline and Fine-Tuning Gene Expression Profiles of Related Metabolic Pathways. |
| Q47119365 | Identification of MsHsp20 Gene Family in Malus sieversii and Functional Characterization of MsHsp16.9 in Heat Tolerance |
| Q54600574 | Isolation and partial characterization of the Chlamydomonas reinhardtii γ-glutamyl kinase |
| Q57476126 | Metabolic origin of the fused aminoacyl tRNA synthetase, glutamyl-prolyl tRNA synthetase |
| Q28296443 | Molecular Mechanisms Modulating Glutamate Kinase Activity. Identification of the Proline Feedback Inhibitor Binding Site |
| Q35274389 | Osmotically Controlled Synthesis of the Compatible Solute Proline Is Critical for Cellular Defense of Bacillus subtilis against High Osmolarity |
| Q37079753 | PYCR2 Mutations cause a lethal syndrome of microcephaly and failure to thrive |
| Q36743471 | Physiological Investigation and Transcriptome Analysis of Polyethylene Glycol (PEG)-Induced Dehydration Stress in Cassava |
| Q37147678 | Proline Mechanisms of Stress Survival |
| Q37171748 | Proline and hydroxyproline metabolism: implications for animal and human nutrition |
| Q36203215 | Proline dehydrogenase is essential for proline protection against hydrogen peroxide-induced cell death |
| Q98281019 | Pyrroline-5-carboxylate synthase senses cellular stress and modulates metabolism by regulating mitochondrial respiration |
| Q92210562 | Quercetin Mediated Salt Tolerance in Tomato through the Enhancement of Plant Antioxidant Defense and Glyoxalase Systems |
| Q38925886 | Reciprocal Control of Thyroid Binding and the Pipecolate Pathway in the Brain |
| Q28115510 | Recurrent De Novo Mutations Affecting Residue Arg138 of Pyrroline-5-Carboxylate Synthase Cause a Progeroid Form of Autosomal-Dominant Cutis Laxa |
| Q47679077 | Structural Biology of Proline Catabolic Enzymes. |
| Q35929427 | Substrate channeling in proline metabolism |
| Q27675774 | The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1 |
| Q64963377 | The multifaceted contributions of mitochondria to cellular metabolism. |
| Q47408311 | Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals |
| Q28255463 | Understanding pyrroline-5-carboxylate synthetase deficiency: clinical, molecular, functional, and expression studies, structure-based analysis, and novel therapy with arginine |
| Q64905771 | Zebrafish Carrying pycr1 Gene Deficiency Display Aging and Multiple Behavioral Abnormalities. |
| Q54985743 | ZmNF-YB16 Overexpression Improves Drought Resistance and Yield by Enhancing Photosynthesis and the Antioxidant Capacity of Maize Plants. |
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