Human Delta1-pyrroline-5-carboxylate synthase: function and regulation

scientific article

Human Delta1-pyrroline-5-carboxylate synthase: function and regulation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00726-008-0075-0
P932PMC publication ID2707934
P698PubMed publication ID18401542
P5875ResearchGate publication ID5450279

P2093author name stringZ Liu
D Valle
S Khalil
G Wan
M Tyler
S Zhaorigetu
C-A A Hu
P2860cites workHyperammonemia with reduced ornithine, citrulline, arginine and proline: a new inborn error caused by a mutation in the gene encoding delta(1)-pyrroline-5-carboxylate synthaseQ24290552
A model for p53-induced apoptosisQ24313374
Cloning, characterization, and expression of cDNAs encoding human delta 1-pyrroline-5-carboxylate dehydrogenaseQ24336950
Arginine metabolism: nitric oxide and beyondQ24531285
Surfing the p53 networkQ28032484
Molecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibitionQ28114960
Eukaryotic aldehyde dehydrogenase (ALDH) genes: human polymorphisms, and recommended nomenclature based on divergent evolution and chromosomal mappingQ28142839
Regulation of enzymes of the urea cycle and arginine metabolismQ28203558
Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signalingQ28235103
Database cloning human delta 1-pyrroline-5-carboxylate synthetase (P5CS) cDNA: a bifunctional enzyme catalyzing the first 2 steps in proline biosynthesisQ28287273
Delta1-pyrroline-5-carboxylate synthase deficiency: neurodegeneration, cataracts and connective tissue manifestations combined with hyperammonaemia and reduced ornithine, citrulline, arginine and prolineQ28290796
Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cellsQ28304332
Coordinate induction of the urea cycle enzymes by glucagon and dexamethasone is accomplished by three different mechanismsQ28580828
Live or let die: the cell's response to p53Q29547663
Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stressesQ34301424
Reactive oxygen species are downstream mediators of p53-dependent apoptosisQ34403292
Molecular targets for green tea in prostate cancer preventionQ35168692
P53 and prognosis: new insights and further complexityQ36010518
A bifunctional enzyme (delta 1-pyrroline-5-carboxylate synthetase) catalyzes the first two steps in proline biosynthesis in plantsQ37234456
A mouse model of gyrate atrophy of the choroid and retina. Early retinal pigment epithelium damage and progressive retinal degenerationQ37356365
The regulatory functions of proline and pyrroline-5-carboxylic acidQ38150343
Metabolism of Proline and the HydroxyprolinesQ40121480
A novel loss-of-function mutation in TP53 in an endometrial cancer cell line and uterine papillary serous carcinoma modelQ40205750
Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis.Q40250385
Global investigation of p53-induced apoptosis through quantitative proteomic profiling using comparative amino acid-coded taggingQ40530125
Arginine synthesis in enterocytes of neonatal pigsQ52206390
A cortisol surge mediates the enhanced expression of pig intestinal pyrroline-5-carboxylate synthase during weaning.Q64915647
Regulation of mRNA levels for five urea cycle enzymes in rat liver by diet, cyclic AMP, and glucocorticoidsQ70185681
Transfer of reducing equivalents into mitochondria by the interconversions of proline and delta 1-pyrroline-5-carboxylateQ71246216
Regulation of human insulin receptor RNA splicing in HepG2 cells: effects of glucocorticoid and low glucose concentrationQ72280800
A new inherited metabolic disease: delta1-pyrroline 5-carboxylate synthetase deficiencyQ74635453
PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cellsQ81489434
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectorganic chemistryQ11351
clinical chemistryQ849994
P304page(s)665-72
P577publication date2008-11-01
P1433published inAmino AcidsQ15757015
P1476titleHuman Delta1-pyrroline-5-carboxylate synthase: function and regulation
P478volume35

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cites work (P2860)
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