EBP50 exerts tumor suppressor activity by promoting cell apoptosis and retarding extracellular signal-regulated kinase activity

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EBP50 exerts tumor suppressor activity by promoting cell apoptosis and retarding extracellular signal-regulated kinase activity is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1017966626
P356DOI10.1007/S00726-009-0437-2
P3181OpenCitations bibliographic resource ID2977912
P698PubMed publication ID20012548
P5875ResearchGate publication ID40689980

P2093author name stringYang Li
Hua Liu
Yan Huang
Junqi He
Li-Cui Sun
Jun-Fang Zheng
P2860cites workPTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signalingQ24303571
Proline-rich tyrosine kinase 2 (Pyk2) promotes proliferation and invasiveness of hepatocellular carcinoma cells through c-Src/ERK activationQ24309608
NHE-RF, a Regulatory Cofactor for Na+-H+Exchange, Is a Common Interactor for Merlin and ERM (MERM) ProteinsQ24320465
Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activityQ24515074
Autocrine PDGFR signaling promotes mammary cancer metastasisQ24545375
EBP50, a beta-catenin-associating protein, enhances Wnt signaling and is over-expressed in hepatocellular carcinomaQ28182609
Human Delta1-pyrroline-5-carboxylate synthase: function and regulationQ28275915
The MAPK signaling cascadeQ28292599
Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesisQ28585214
ERK and the F-box protein betaTRCP target STAT1 for degradationQ28590914
Na+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cellsQ28592252
The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.Q30479321
Suppression of breast cancer cell growth by Na+/H+ exchanger regulatory factor 1 (NHERF1)Q35633702
Contact-dependent inhibition of EGFR signaling by Nf2/MerlinQ36118464
Na/H exchange regulatory factor 1, a novel AKT-associating protein, regulates extracellular signal-regulated kinase signaling through a B-Raf-mediated pathway.Q36536571
PDGF receptors as targets in tumor treatmentQ36786075
PTEN: its deregulation and tumorigenesis.Q36935178
Roles of NHERF1/EBP50 in cancerQ37264782
The Na+/H+ exchanger regulatory factor stabilizes epidermal growth factor receptors at the cell surfaceQ37657288
Cortical stabilization of beta-catenin contributes to NHERF1/EBP50 tumor suppressor functionQ38304289
Mutant rat strain lacking D-amino-acid oxidaseQ39948749
RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivoQ39975996
GLI1 repression of ERK activity correlates with colony formation and impaired migration in human epidermal keratinocytesQ40012240
Induction of apoptosis in MCF-7 and MDA-MB-231 breast cancer cells by Oligonol is mediated by Bcl-2 family regulation and MEK/ERK signalingQ40122864
7,8-Dihydroxy-4-methylcoumarin induces apoptosis of human lung adenocarcinoma cells by ROS-independent mitochondrial pathway through partial inhibition of ERK/MAPK signalingQ40136164
Extracellular signal-regulated kinase activation by parathyroid hormone in distal tubule cellsQ40208196
A NHERF binding site links the betaPDGFR to the cytoskeleton and regulates cell spreading and migrationQ40552003
Expression profiling of mammary carcinoma cell lines: correlation of in vitro invasiveness with expression of CD24.Q40635382
NHERF (Na+/H+ exchanger regulatory factor) gene mutations in human breast cancerQ45092731
The beta1-adrenergic receptor mediates extracellular signal-regulated kinase activation via GalphasQ46225959
Role of transglutaminase 2 in quercetin-induced differentiation of B16-F10 murine melanoma cellsQ46439526
The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylationQ46694931
A complexity-based method for predicting protein subcellular locationQ51870852
A germ line mutation in the death domain of DAPK-1 inactivates ERK-induced apoptosisQ52576454
Inhibition of intracellular peroxides and apoptosis of lymphocytes in lupus-prone B/W mice by dietary n-6 and n-3 lipids with calorie restrictionQ74539144
Oridonin-induced A431 cell apoptosis partially through blockage of the Ras/Raf/ERK signal pathwayQ79656081
Expression and clinicopathological significance of oestrogen-responsive ezrin-radixin-moesin-binding phosphoprotein 50 in breast cancerQ80530484
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
positive regulation of intrinsic apoptotic signaling pathwayQ14818096
SLC9A3 regulator 1Q21112493
P304page(s)1261-8
P577publication date2010-04-01
P1433published inAmino AcidsQ15757015
P1476titleEBP50 exerts tumor suppressor activity by promoting cell apoptosis and retarding extracellular signal-regulated kinase activity
P478volume38

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cites work (P2860)
Q24323184Breast cancer-derived K172N, D301V mutations abolish Na+/H+ exchanger regulatory factor 1 inhibition of platelet-derived growth factor receptor signaling
Q43106592Clinical significance of EBP50 overexpression assessed by quantum dot analysis in gastric cancer
Q36319689EBP50 inhibits EGF-induced breast cancer cell proliferation by blocking EGFR phosphorylation
Q38966467EBP50 inhibits the migration and invasion of human breast cancer cells via LIMK/cofilin and the PI3K/Akt/mTOR/MMP signaling pathway
Q47250144EBP50 suppresses the proliferation of MCF-7 human breast cancer cells via promoting Beclin-1/p62-mediated lysosomal degradation of c-Myc.
Q36163714High-Resolution 4C Reveals Rapid p53-Dependent Chromatin Reorganization of the CDKN1A Locus in Response to Stress
Q33932203Immunohistochemical analysis of ezrin-radixin-moesin-binding phosphoprotein 50 in prostatic adenocarcinoma
Q26800001Insulin-like growth factor and epidermal growth factor signaling in breast cancer cell growth: focus on endocrine resistant disease
Q37584289Low level of PDZ domain containing 1 (PDZK1) predicts poor clinical outcome in patients with clear cell renal cell carcinoma
Q92839076Mcl-1 signals pathway inhibitors in mouse peritoneal macrophage apoptosis infected with the Xinjiang strain of M. tuberculosis
Q37631384NHERF1 Enhances Cisplatin Sensitivity in Human Cervical Cancer Cells
Q35998570NHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains
Q33597837Reduced EBP50 expression levels are correlated with unfavorable clinicopathological features of extrahepatic bile duct carcinoma and promote the proliferation and migration of QBC939 cells
Q26863645Regulation of G Protein-Coupled Receptor Function by Na+/H+Exchange Regulatory Factors
Q55061344Regulation of β2-adrenergic receptor cell surface expression by interaction with cystic fibrosis transmembrane conductance regulator-associated ligand (CAL).
Q36808215SLC9A3R1 stimulates autophagy via BECN1 stabilization in breast cancer cells
Q36538416Temporal and spatial regulation of ezrin-radixin-moesin-binding phosphoprotein-50-kDa (EBP50) during embryo implantation in mouse uterus
Q39343398The detection of EBP50 expression using quantum dot immunohistochemistry in pancreatic cancer tissue and down-regulated EBP50 effect on PC-2 cells
Q39181929Tumor suppressor function of ezrin-radixin-moesin-binding phosphoprotein-50 through β-catenin/E-cadher in pathway in human hepatocellular cancer

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