Na+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells

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Na+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1014912489
P356DOI10.1186/BCR1846
P8608Fatcat IDrelease_wwlcqewv4zdnlav4dqhyy3bezu
P3181OpenCitations bibliographic resource ID2977913
P932PMC publication ID2374956
P698PubMed publication ID18190691
P5875ResearchGate publication ID5660260

P2093author name stringYong Pan
Jia Le Dai
Edward J. Weinman
P2860cites workInteraction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinaseQ22253438
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PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signalingQ24303571
The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchangeQ24310009
Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2Q24313491
Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activityQ24515074
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cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory proteinQ24569613
Yes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50Q24683312
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Regulation of phospholipase C-beta 3 activity by Na+/H+ exchanger regulatory factor 2Q28140591
G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interactionQ28142079
A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptorQ28145098
Peptide binding consensus of the NHE‐RF‐PDZ1 domain matches the C‐terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)Q28272686
An Apical PDZ Protein Anchors the Cystic Fibrosis Transmembrane Conductance Regulator to the CytoskeletonQ28277503
Pten is essential for embryonic development and tumour suppressionQ28509238
Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumorsQ28510087
Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wastingQ28510488
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemiaQ29547900
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumorsQ29618610
Apoptosis in cancerQ33846227
CAMP-mediated inhibition of the renal brush border membrane Na+-H+ exchanger requires a dissociable phosphoprotein cofactorQ33904680
An atlas of mouse mammary gland developmentQ34125577
Inhibition of protein kinase B/Akt. implications for cancer therapyQ34145575
Chk1 is haploinsufficient for multiple functions critical to tumor suppressionQ34334239
Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative.Q34370094
Expanding the role of NHERF, a PDZ-domain containing protein adapter, to growth regulationQ34405532
Regulation of cystic fibrosis transmembrane conductance regulator single-channel gating by bivalent PDZ-domain-mediated interactionQ34662162
Suppression of breast cancer cell growth by Na+/H+ exchanger regulatory factor 1 (NHERF1)Q35633702
Allelotype of 28 human breast cancer cell lines and xenograftsQ36673552
PDGF receptors as targets in tumor treatmentQ36786075
Allelotyping of ductal carcinoma in situ of the breast: deletion of loci on 8p, 13q, 16q, 17p and 17q.Q38480342
Inhibition of platelet-derived growth factor receptor signaling restricts the growth of human breast cancer in the bone of nude mice.Q39706169
Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell linesQ40168416
Implication of the MAGI-1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness.Q40475289
A NHERF binding site links the betaPDGFR to the cytoskeleton and regulates cell spreading and migrationQ40552003
Estrogen receptor inducibility of the human Na+/H+ exchanger regulatory factor/ezrin-radixin-moesin binding protein 50 (NHE-RF/EBP50) gene involving multiple half-estrogen response elementsQ40714901
A phase II trial of imatinib mesylate monotherapy in patients with metastatic breast cancer.Q43487632
Phosphorylation and cell cycle-dependent regulation of Na+/H+ exchanger regulatory factor-1 by Cdc2 kinaseQ43726481
Alternative splicing disrupts a nuclear localization signal in spleen tyrosine kinase that is required for invasion suppression in breast cancerQ44542378
Haplo-insufficiency of BRCA1 in sporadic breast cancerQ44564103
NHERF (Na+/H+ exchanger regulatory factor) gene mutations in human breast cancerQ45092731
A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressorQ48129277
Apoptosis in the terminal endbud of the murine mammary gland: a mechanism of ductal morphogenesisQ52523693
17q21-q25 aberrations in breast cancer: combined allelotyping and CGH analysis reveals 5 regions of allelic imbalance among which two correspond to DNA amplificationQ57287554
Detailed deletion analysis of sporadic breast tumors defines an interstitial region of allelic loss on 17q25Q71722047
A region of interstitial 17q25 allelic loss in ovarian tumors coincides with a defined region of loss in breast tumorsQ73337947
Four regions of allelic imbalance on 17q12-qter associated with high-grade breast tumorsQ73964420
Expression of growth factors, growth inhibiting factors, and their receptors in invasive breast cancer. I: An inventory in search of autocrine and paracrine loopsQ74532039
Roles of the matrix metalloproteinases in mammary gland development and cancerQ77579546
Estrogen receptor regulation of the Na+/H+ exchange regulatory factorQ77932795
P433issue1
P921main subjectbreast cancerQ128581
Phosphatase and tensin homologQ14878408
Solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1Q21496248
P304page(s)R5
P577publication date2008-01-01
P1433published inBreast Cancer ResearchQ2208481
P1476titleNa+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells
P478volume10

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cites work (P2860)
Q24323184Breast cancer-derived K172N, D301V mutations abolish Na+/H+ exchanger regulatory factor 1 inhibition of platelet-derived growth factor receptor signaling
Q24298046Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling
Q35140477E6 and E7 from human papillomavirus type 16 cooperate to target the PDZ protein Na/H exchange regulatory factor 1.
Q22001537EBP50 exerts tumor suppressor activity by promoting cell apoptosis and retarding extracellular signal-regulated kinase activity
Q36319689EBP50 inhibits EGF-induced breast cancer cell proliferation by blocking EGFR phosphorylation
Q37150777Ezrin-radixin-moesin-binding phosphoprotein (EBP50), an estrogen-inducible scaffold protein, contributes to biliary epithelial cell proliferation
Q51065760Group II metabotropic glutamate receptor interactions with NHERF scaffold proteins: Implications for receptor localization in brain
Q36163714High-Resolution 4C Reveals Rapid p53-Dependent Chromatin Reorganization of the CDKN1A Locus in Response to Stress
Q93335769Inhibition of ezrin causes PKCα-mediated internalization of erbb2/HER2 tyrosine kinase in breast cancer cells
Q47756210Involvement of platelet-derived growth factor ligands and receptors in tumorigenesis
Q54566655Microarray analysis reveals genes and functional networks relevant to the predisposition to inverted teats in pigs.
Q92005259NHERF1 Is Required for Localization of PMCA2 and Suppression of Early Involution in the Female Lactating Mammary Gland
Q37688175NHERF1, a novel GPER associated protein, increases stability and activation of GPER in ER-positive breast cancer
Q36288731NHERF1/EBP50 controls lactation by establishing basal membrane polarity complexes with prolactin receptor
Q34096013NHERF1/EBP50 in Breast Cancer: Clinical Perspectives
Q43238651NHERF1: molecular brake on the PI3K pathway in breast cancer
Q39459665Na(+)/H(+) Exchanger Regulatory Factor 1 (NHERF1) Is Required for the Estradiol-Dependent Increase of Phosphatase and Tensin Homolog (PTEN) Protein Expression
Q34202681PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control
Q36211287PTEN inhibits macrophage polarization from M1 to M2 through CCL2 and VEGF-A reduction and NHERF-1 synergism
Q28115966PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma
Q36066974Prognostic significance of peroxiredoxin 1 and ezrin-radixin-moesin-binding phosphoprotein 50 in cholangiocarcinoma
Q26863645Regulation of G Protein-Coupled Receptor Function by Na+/H+Exchange Regulatory Factors
Q39076960Role of the PDZ-scaffold protein NHERF1/EBP50 in cancer biology: from signaling regulation to clinical relevance.
Q91666333Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle
Q47728022Systematic Proteogenomic Approach To Exploring a Novel Function for NHERF1 in Human Reproductive Disorder: Lessons for Exploring Missing Proteins.
Q37301851The cellular distribution of Na+/H+ exchanger regulatory factor 1 is determined by the PDZ-I domain and regulates the malignant progression of breast cancer.
Q35621438The scaffolding protein EBP50 promotes vascular smooth muscle cell proliferation and neointima formation by regulating Skp2 and p21(cip1).
Q38714954The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2.
Q39181929Tumor suppressor function of ezrin-radixin-moesin-binding phosphoprotein-50 through β-catenin/E-cadher in pathway in human hepatocellular cancer

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