Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase

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Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M909741199
P698PubMed publication ID10748157

P2093author name stringQ Gu
Y Wu
J Lee
D Dowbenko
L A Lasky
S Spencer
R Laura
P2860cites workThe lipid phosphatase activity of PTEN is critical for its tumor supressor functionQ22007981
The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal regionQ22010498
Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteinsQ24310521
Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1Q24310654
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphateQ24317714
A novel multiple PDZ domain-containing molecule interacting with N-methyl-D-aspartate receptors and neuronal cell adhesion proteinsQ24321831
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTENQ24322051
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctionsQ24672971
PSTPIP: a tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphataseQ24679587
Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane associationQ27620298
Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZQ27732927
Crystal structure of a PDZ domainQ27733300
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancerQ27860985
SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic densityQ28235849
PDZ domains: targeting signalling molecules to sub-membranous sitesQ28242408
MAGI-1, a membrane-associated guanylate kinase with a unique arrangement of protein-protein interaction domainsQ28256306
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancersQ28306997
Pten is essential for embryonic development and tumour suppressionQ28509238
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTENQ28513537
Recognition of unique carboxyl-terminal motifs by distinct PDZ domainsQ29547580
Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs largeQ30176301
PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cellsQ33586807
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathwayQ33599964
Inhibition of patterned cell shape change and cell invasion by Discs large during Drosophila oogenesisQ35192400
The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cellsQ35574865
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expressionQ36067596
Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathwaysQ36256326
In vitro loss of heterozygosity targets the PTEN/MMAC1 gene in melanomaQ36260162
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domainQ36818855
Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interactionQ40957062
Protein-protein interactions: PDZ domain networksQ41238394
PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyondQ41596068
Ion channel targeting in neuronsQ41639258
Mechanisms and consequences of activation of protein kinase B/AktQ41751003
Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.Q42824933
PTEN: sometimes taking it off can be better than putting it on.Q43104730
PDZ proteins organize synaptic signaling pathwaysQ46332824
A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascadeQ47070943
PTEN and inherited hamartoma-cancer syndromesQ47852476
Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brainQ48317594
Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex.Q52176221
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in miceQ58378937
P433issue28
P407language of work or nameEnglishQ1860
P921main subjectintracellular signal transductionQ14851952
Membrane associated guanylate kinase, WW and PDZ domain containing 3Q21112534
P304page(s)21477-85
P577publication date2000-07-14
P1433published inJournal of Biological ChemistryQ867727
P1476titleInteraction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase
P478volume275

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