| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1014851134 |
| P356 | DOI | 10.1038/SJ.ONC.1205296 |
| P698 | PubMed publication ID | 11948419 |
| P5875 | ResearchGate publication ID | 11419047 |
| P50 | author | Gordon B. Mills | Q28086262 |
| P2093 | author name string | Yiling Lu | |
| Yuexi Shi | |||
| W K Alfred Yung | |||
| Michael A Davies | |||
| Dimpy Koul | |||
| Samar A Jasser | |||
| Ruijun Shen | |||
| P2860 | cites work | The lipid phosphatase activity of PTEN is critical for its tumor supressor function | Q22007981 |
| The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region | Q22010498 | ||
| Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase | Q22253438 | ||
| Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2 | Q22253866 | ||
| Phosphorylation of the PTEN tail regulates protein stability and function | Q22254305 | ||
| The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation | Q24290417 | ||
| The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
| Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN | Q24322051 | ||
| P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
| Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association | Q27620298 | ||
| PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
| PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway | Q28139300 | ||
| Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate | Q28301966 | ||
| Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
| Pten is essential for embryonic development and tumour suppression | Q28509238 | ||
| Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN | Q28513537 | ||
| Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems | Q28586004 | ||
| Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome | Q29615538 | ||
| The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase | Q29618387 | ||
| Reciprocal regulation of Hck activity by phosphorylation of Tyr(527) and Tyr(416). Effect of introducing a high affinity intramolecular SH2 ligand | Q30175264 | ||
| PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis | Q33723736 | ||
| Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase | Q34429291 | ||
| Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain | Q36818855 | ||
| Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase | Q40972780 | ||
| The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells | Q42481082 | ||
| Germline mutations in PTEN are present in Bannayan-Zonana syndrome | Q48046915 | ||
| A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region | Q48205638 | ||
| Src homology domain 2-containing tyrosine phosphatase 2 associates with intercellular adhesion molecule 1 to regulate cell survival | Q73919610 | ||
| P433 | issue | 15 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2357-2364 | |
| P577 | publication date | 2002-04-01 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity | |
| P478 | volume | 21 |
| Q38974986 | A biosensor to monitor dynamic regulation and function of tumour suppressor PTEN in living cells |
| Q37626395 | A high Notch pathway activation predicts response to γ secretase inhibitors in proneural subtype of glioma tumor-initiating cells |
| Q44188511 | A new insight into structural and functional impact of single-nucleotide polymorphisms in PTEN gene |
| Q41552553 | APOBEC3G acts as a therapeutic target in mesenchymal gliomas by sensitizing cells to radiation-induced cell death |
| Q37203000 | Antitumor activity of NVP-BKM120--a selective pan class I PI3 kinase inhibitor showed differential forms of cell death based on p53 status of glioma cells |
| Q39739265 | Cellular and in vivo activity of a novel PI3K inhibitor, PX-866, against human glioblastoma |
| Q54618528 | Chronic central leptin infusion modifies the response to acute central insulin injection by reducing the interaction of the insulin receptor with IRS2 and increasing its association with SOCS3. |
| Q28566685 | Critical role of PTEN in the coupling between PI3K/Akt and JNK1/2 signaling in ischemic brain injury |
| Q38911461 | Effect of Notch expression in glioma stem cells on therapeutic response to chemo-radiotherapy in recurrent glioblastoma |
| Q35085321 | Establishment and characterization of clinically relevant models of ependymoma: a true challenge for targeted therapy |
| Q38980829 | Identification of nucleolus-localized PTEN and its function in regulating ribosome biogenesis |
| Q38275382 | Kinases, tails and more: regulation of PTEN function by phosphorylation |
| Q26738538 | Molecular mechanisms of peritoneal dissemination in gastric cancer |
| Q54273990 | Mutational and expressional analyses of PTEN gene in colorectal cancer from Northern India. |
| Q42218359 | Nongenomic Mechanisms of PTEN Regulation |
| Q24337323 | Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner |
| Q42076186 | Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation |
| Q28218655 | PTEN and myotubularin phosphatases: from 3-phosphoinositide dephosphorylation to disease |
| Q37259680 | PTEN and the PI3-kinase pathway in cancer |
| Q24555751 | PTEN as an effector in the signaling of antimigratory G protein-coupled receptor |
| Q50288818 | PTEN cancer mutants do not dephosphorylate PIP3 |
| Q40181453 | PTEN down regulates AP-1 and targets c-fos in human glioma cells via PI3-kinase/Akt pathway |
| Q37243759 | PTEN enhances TNF-induced apoptosis through modulation of nuclear factor-kappaB signaling pathway in human glioma cells |
| Q24528114 | PTEN function: how normal cells control it and tumour cells lose it |
| Q38198345 | PTEN function: the long and the short of it. |
| Q28265138 | Peroxiredoxin 1 and its role in cell signaling |
| Q24316318 | Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity |
| Q47691876 | Regulation of the tumor suppressor PTEN by natural anticancer compounds |
| Q48413426 | Relationship between PTEN gene expression and differentiation of human glioma |
| Q36212896 | Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240. |
| Q47369447 | Suppression of glioblastoma growth and angiogenesis through molecular targeting of methionine aminopeptidase-2. |
| Q35971862 | The APC/C Ubiquitin Ligase: From Cell Biology to Tumorigenesis |
| Q61812765 | The Oncogene Addiction Switch from NOTCH to PI3K Requires Simultaneous Targeting of NOTCH and PI3K Pathway Inhibition in Glioblastoma |
| Q39365663 | The functions of tumor suppressor PTEN in innate and adaptive immunity |
| Q42598141 | The p110delta isoform of PI 3-kinase negatively controls RhoA and PTEN. |
| Q35758225 | Treatment with sodium orthovanadate reduces blood-brain barrier disruption via phosphatase and tensin homolog deleted on chromosome 10 (PTEN) phosphorylation in experimental subarachnoid hemorrhage |
| Q37270444 | Understanding PTEN regulation: PIP2, polarity and protein stability |
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