The Mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair

scientific article

The Mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.22.9.3078-3088.2002
P3181OpenCitations bibliographic resource ID1313711
P932PMC publication ID133769
P698PubMed publication ID11940665
P5875ResearchGate publication ID11425095

P2093author name stringG Shirleen Roeder
Hideo Tsubouchi
P2860cites workSister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiaeQ24532829
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiaeQ24548535
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiaeQ27861085
Meiotic chromosomes: it takes two to tangoQ27930023
Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexesQ27931495
A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis.Q27931673
The budding yeast Msh4 protein functions in chromosome synapsis and the regulation of crossover distributionQ27931846
RecA homologs Dmc1 and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis.Q27932144
Meiotic chromosome morphology and behavior in zip1 mutants of Saccharomyces cerevisiae.Q27932528
The pachytene checkpoint prevents accumulation and phosphorylation of the meiosis-specific transcription factor Ndt80Q27933010
Molecular cloning and characterization of a novel TBP-1 interacting protein (TBPIP):enhancement of TBP-1 action on Tat by TBPIP.Q34443995
Enzymes and molecular mechanisms of genetic recombinationQ35671065
A novel meiosis-specific protein of fission yeast, Meu13p, promotes homologous pairing independently of homologous recombinationQ39645555
Meiotic sister chromatid recombinationQ40373261
Telomere-mediated chromosome pairing during meiosis in budding yeastQ40445528
Meiosis in asynaptic yeastQ41973823
Identification of double Holliday junctions as intermediates in meiotic recombination.Q54599520
Roles for two RecA homologs in promoting meiotic chromosome synapsisQ54601107
Extensive 3'-overhanging, single-stranded DNA associated with the meiosis-specific double-strand breaks at the ARG4 recombination initiation siteQ64389995
Chromosome pairing via multiple interstitial interactions before and during meiosis in yeastQ72034931
DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progressionQ27933115
Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like proteinQ27933995
Zip2, a meiosis-specific protein required for the initiation of chromosome synapsisQ27934770
NDT80, a meiosis-specific gene required for exit from pachytene in Saccharomyces cerevisiaeQ27935026
Yeast mer1 mutants display reduced levels of meiotic recombinationQ27935285
A role for Ddc1 in signaling meiotic double-strand breaks at the pachytene checkpointQ27936045
Homologous pairing is reduced but not abolished in asynaptic mutants of yeastQ27936156
Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathwayQ27936249
Organization of the yeast Zip1 protein within the central region of the synaptonemal complexQ27937024
The meiosis-specific Hop2 protein of S. cerevisiae ensures synapsis between homologous chromosomesQ27937163
Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPaseQ27937378
A screen for genes required for meiosis and spore formation based on whole-genome expression.Q27937629
Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 proteinQ27937922
The transcriptional program of sporulation in budding yeastQ27938344
The pachytene checkpoint in S. cerevisiae depends on Swe1-mediated phosphorylation of the cyclin-dependent kinase Cdc28.Q27939521
Zip3 provides a link between recombination enzymes and synaptonemal complex proteinsQ27939710
New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sitesQ28131597
New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiaeQ28131599
Two differentially regulated mRNAs with different 5' ends encode secreted with intracellular forms of yeast invertaseQ28131607
Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiaeQ28140402
Differential timing and control of noncrossover and crossover recombination during meiosisQ28207440
Coiled coils: a highly versatile protein folding motifQ29616419
ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsisQ29618281
The single-end invasion: an asymmetric intermediate at the double-strand break to double-holliday junction transition of meiotic recombinationQ29618523
In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeastQ29618550
Mechanism and control of meiotic recombination initiationQ29618789
Use of polymerase chain reaction epitope tagging for protein tagging in Saccharomyces cerevisiaeQ29620841
High copy number suppression of the meiotic arrest caused by a dmc1 mutation: REC114 imposes an early recombination block and RAD54 promotes a DMC1-independent DSB repair pathway.Q30794876
Molecular cloning and characterization of a human homologue of TBPIP, a BRCA1 locus-related geneQ33901548
Use of a ring chromosome and pulsed-field gels to study interhomolog recombination, double-strand DNA breaks and sister-chromatid exchange in yeastQ33956016
A chromosome containing HOT1 preferentially receives information during mitotic interchromosomal gene conversionQ33956266
Heteroduplex DNA formation and homolog pairing in yeast meiotic mutantsQ33965764
The efficiency of meiotic recombination between dispersed sequences in Saccharomyces cerevisiae depends upon their chromosomal location.Q33968416
The pachytene checkpointQ34023299
How do meiotic chromosomes meet their homologous partners?: lessons from fission yeastQ34269339
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
Mnd1p YGL183CQ27551737
P304page(s)3078-3088
P577publication date2002-05-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleThe Mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair
P478volume22

Reverse relations

cites work (P2860)
Q53332345Ahp2 (Hop2) function in Arabidopsis thaliana (Ler) is required for stabilization of close alignment and synaptonemal complex formation except for the two short arms that contain nucleolus organizer regions.
Q21092188An expanded inventory of conserved meiotic genes provides evidence for sex in Trichomonas vaginalis
Q34897771Analysis of close stable homolog juxtaposition during meiosis in mutants of Saccharomyces cerevisiae
Q33252028AtMND1 is required for homologous pairing during meiosis in Arabidopsis
Q33604620Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates
Q35893640Bipartite stimulatory action of the Hop2-Mnd1 complex on the Rad51 recombinase.
Q27937353Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired
Q22122460Clarifying the mechanics of DNA strand exchange in meiotic recombination
Q33340319Comparative genome analysis of filamentous fungi reveals gene family expansions associated with fungal pathogenesis
Q40357615Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1.
Q28261702Connecting by breaking and repairing: mechanisms of DNA strand exchange in meiotic recombination
Q34025845Crossover invariance determined by partner choice for meiotic DNA break repair
Q35476267Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination
Q27931695Csm4-dependent telomere movement on nuclear envelope promotes meiotic recombination
Q36392901D-loop formation by Brh2 protein of Ustilago maydis
Q37643441DNA repair pathways in trypanosomatids: from DNA repair to drug resistance.
Q34931255DNA strand exchange and RecA homologs in meiosis
Q92351337Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination
Q34567177Does crossover interference count in Saccharomyces cerevisiae?
Q93015440Dynamic interactions of the homologous pairing 2 (Hop2)-meiotic nuclear divisions 1 (Mnd1) protein complex with meiotic presynaptic filaments in budding yeast
Q24804600Evidence from comparative genomics for a complete sexual cycle in the 'asexual' pathogenic yeast Candida glabrata
Q36877568Expression analysis of MND1/GAJ, SPATA22, GAPDHS and ACR genes in testicular biopsies from non-obstructive azoospermia (NOA) patients
Q39455987Factors affecting splicing strength of yeast genes
Q37656485From meiosis to postmeiotic events: uncovering the molecular roles of the meiosis-specific recombinase Dmc1.
Q48149888Fundamental cell cycle kinases collaborate to ensure timely destruction of the synaptonemal complex during meiosis
Q34690840Gene expression analysis of parthenogenetic embryonic development of the pea aphid, Acyrthosiphon pisum, suggests that aphid parthenogenesis evolved from meiotic oogenesis
Q34786693HOP2-MND1 modulates RAD51 binding to nucleotides and DNA.
Q27929751Heterodimeric complexes of Hop2 and Mnd1 function with Dmc1 to promote meiotic homolog juxtaposition and strand assimilation
Q33987524Homologous chromosome interactions in meiosis: diversity amidst conservation.
Q34375685Homologous recombination occurs in Entamoeba and is enhanced during growth stress and stage conversion
Q37121869Hop2 and Sae3 Are Required for Dmc1-Mediated Double-Strand Break Repair via Homolog Bias during Meiosis
Q34388692Hop2-Mnd1 condenses DNA to stimulate the synapsis phase of DNA strand exchange
Q24671981Hop2/Mnd1 acts on two critical steps in Dmc1-promoted homologous pairing
Q91755842Identification of potential diagnostic and therapeutic target genes for lung squamous cell carcinoma
Q30498306Identification of the meiotic life cycle stage of Trypanosoma brucei in the tsetse fly
Q38172111Investigations of homologous recombination pathways and their regulation
Q33695241Irregular telomeres impair meiotic synapsis and recombination in mice
Q41023071Mcp7, a meiosis-specific coiled-coil protein of fission yeast, associates with Meu13 and is required for meiotic recombination
Q37518627Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing
Q33289792Meiosis and small ubiquitin-related modifier (SUMO)-conjugating enzyme, Ubc9.
Q27940335Meiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulation
Q92128948Meiotic gene activation in somatic and germ cell tumours
Q36900926Meiotic recombination in Caenorhabditis elegans
Q27930146Mnd1/Hop2 facilitates Dmc1-dependent interhomolog crossover formation in meiosis of budding yeast
Q53624436Molecular activities of meiosis-specific proteins Hop2, Mnd1, and the Hop2-Mnd1 complex.
Q36226840Molecular aspects of meiotic chromosome synapsis and recombination
Q35668870Novel attributes of Hed1 affect dynamics and activity of the Rad51 presynaptic filament during meiotic recombination
Q47358994Positive role of the mammalian TBPIP/HOP2 protein in DMC1-mediated homologous pairing.
Q35619405Prelude to a division
Q93270905RPA resolves conflicting activities of accessory proteins during reconstitution of Dmc1-mediated meiotic recombination
Q53644657Recruitment of RecA homologs Dmc1p and Rad51p to the double-strand break repair site initiated by meiosis-specific endonuclease VDE (PI-SceI).
Q27934381Remodeling of the Rad51 DNA strand-exchange protein by the Srs2 helicase
Q27933817SSP2 and OSW1, two sporulation-specific genes involved in spore morphogenesis in Saccharomyces cerevisiae.
Q50928315Saccharomyces cerevisiae Red1 protein exhibits nonhomologous DNA end-joining activity and potentiates Hop1-promoted pairing of double-stranded DNA.
Q35882461Small Rad51 and Dmc1 Complexes Often Co-occupy Both Ends of a Meiotic DNA Double Strand Break
Q53641161Stimulation of DNA strand exchange by the human TBPIP/Hop2-Mnd1 complex.
Q35829344Stimulation of fission yeast and mouse Hop2-Mnd1 of the Dmc1 and Rad51 recombinases
Q52646335Sufficient amounts of functional HOP2/MND1 complex promote interhomolog DNA repair but are dispensable for intersister DNA repair during meiosis in Arabidopsis.
Q35804006Synapsis-dependent and -independent mechanisms stabilize homolog pairing during meiotic prophase in C. elegans
Q26824803Ten years of gene discovery for meiotic event control in rice
Q52563802The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination.
Q34282575The Hop2 protein has a direct role in promoting interhomolog interactions during mouse meiosis
Q27940329The budding yeast mei5 and sae3 proteins act together with dmc1 during meiotic recombination
Q37173686The cytogenetics of homologous chromosome pairing in meiosis in plants
Q37606970The dual role of HOP2 in mammalian meiotic homologous recombination
Q90728910The ectopic expression of meiCT genes promotes meiomitosis and may facilitate carcinogenesis
Q21183986The genome and transcriptome of the enteric parasite Entamoeba invadens, a model for encystation
Q52096457The importance of genetic recombination for fidelity of chromosome pairing in meiosis.
Q33302679The interplay of RecA-related proteins and the MND1-HOP2 complex during meiosis in Arabidopsis thaliana
Q34073844The third exon of the budding yeast meiotic recombination gene HOP2 is required for calcium-dependent and recombinase Dmc1-specific stimulation of homologous strand assimilation.
Q24339012XX ovarian dysgenesis is caused by a PSMC3IP/HOP2 mutation that abolishes coactivation of estrogen-driven transcription

Search more.