Meiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulation

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Meiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulation is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1003978
P3181OpenCitations bibliographic resource ID826702
P932PMC publication ID3868528
P698PubMed publication ID24367271
P5875ResearchGate publication ID259456968

P2093author name stringNeil Hunter
Douglas K Bishop
Chu-Chun Huang
Jennifer Grubb
Jessica P Lao
Drew Thacker
Chih-Ying Lee
Michael E Dresser
Veronica Cloud
P2860cites workThe control of chiasma distribution.Q52522587
Molecular activities of meiosis-specific proteins Hop2, Mnd1, and the Hop2-Mnd1 complex.Q53624436
Repositioning of aurora B promoted by chiasmata ensures sister chromatid mono-orientation in meiosis I.Q54560273
Identification of double Holliday junctions as intermediates in meiotic recombination.Q54599520
Identification of joint molecules that form frequently between homologs but rarely between sister chromatids during yeast meiosisQ64389750
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Chromosome pairing via multiple interstitial interactions before and during meiosis in yeastQ72034931
Synaptonemal complex karyotyping in spermatocytes of the Chinese hamster (Cricetulus griseus). IV. Light and electron microscopy of synapsis and nucleolar development by silver stainingQ72605169
Meiotic cells monitor the status of the interhomolog recombination complexQ72988432
Phosphorylation and the creation of interhomolog bias during meiosis in yeastQ82591649
Frequent and efficient use of the sister chromatid for DNA double-strand break repair during budding yeast meiosisQ21092719
Synthesis-dependent strand annealing in meiosisQ21145860
Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiaeQ24532829
Tid1/Rdh54 promotes colocalization of rad51 and dmc1 during meiotic recombinationQ24648825
A link between meiotic prophase progression and crossover controlQ25257844
A new protein complex promoting the assembly of Rad51 filamentsQ27677299
Heterodimeric complexes of Hop2 and Mnd1 function with Dmc1 to promote meiotic homolog juxtaposition and strand assimilationQ27929751
Mnd1/Hop2 facilitates Dmc1-dependent interhomolog crossover formation in meiosis of budding yeastQ27930146
Yeast Pch2 promotes domainal axis organization, timely recombination progression, and arrest of defective recombinosomes during meiosisQ27931107
The yeast Red1 protein localizes to the cores of meiotic chromosomesQ27931793
RecA homologs Dmc1 and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis.Q27932144
Rad52 promotes postinvasion steps of meiotic double-strand-break repairQ27932985
DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progressionQ27933115
Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like proteinQ27933995
Hed1 regulates Rad51-mediated recombination via a novel mechanismQ27934270
Rad51 is an accessory factor for Dmc1-mediated joint molecule formation during meiosisQ27934904
Saccharomyces cerevisiae Dmc1 protein promotes renaturation of single-strand DNA (ssDNA) and assimilation of ssDNA into homologous super-coiled duplex DNA.Q27935123
Saccharomyces cerevisiae checkpoint genes MEC1, RAD17 and RAD24 are required for normal meiotic recombination partner choiceQ27935546
The roles of MAD1, MAD2 and MAD3 in meiotic progression and the segregation of nonexchange chromosomesQ27935576
A meiosis-specific protein kinase homolog required for chromosome synapsis and recombinationQ27936141
Mek1 kinase activity functions downstream of RED1 in the regulation of meiotic double strand break repair in budding yeastQ27936239
Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathwayQ27936249
Saccharomyces cerevisiae recA homologues RAD51 and DMC1 have both distinct and overlapping roles in meiotic recombinationQ27936736
Polo-like kinase Cdc5 drives exit from pachytene during budding yeast meiosisQ27936840
Crossover/noncrossover differentiation, synaptonemal complex formation, and regulatory surveillance at the leptotene/zygotene transition of meiosisQ27936900
The Mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repairQ27937197
Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impairedQ27937353
Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination.Q27938325
Differential timing and control of noncrossover and crossover recombination during meiosisQ28207440
Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvaseQ28264475
Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand break resection and resolution of double Holliday junctionsQ28301386
Robust crossover assurance and regulated interhomolog access maintain meiotic crossover numberQ28729155
ATM controls meiotic double-strand-break formationQ28742900
Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombinationQ29615272
ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsisQ29618281
The single-end invasion: an asymmetric intermediate at the double-strand break to double-holliday junction transition of meiotic recombinationQ29618523
Meiotic chromosomes: integrating structure and functionQ29618524
High copy number suppression of the meiotic arrest caused by a dmc1 mutation: REC114 imposes an early recombination block and RAD54 promotes a DMC1-independent DSB repair pathway.Q30794876
The Analysis of Tetrad DataQ31095632
STED microscopy with a supercontinuum laser sourceQ33346148
Pch2 links chromosome axis remodeling at future crossover sites and crossover distribution during yeast meiosisQ33486503
The synaptonemal complex protein, Zip1, promotes the segregation of nonexchange chromosomes at meiosis I.Q33640114
The logic and mechanism of homologous recombination partner choiceQ33724834
Trying to Avoid Your SisterQ33728150
Chiasmata promote monopolar attachment of sister chromatids and their co-segregation toward the proper pole during meiosis I.Q33851572
HOP1: a yeast meiotic pairing geneQ33955117
Direct and indirect control of the initiation of meiotic recombination by DNA damage checkpoint mechanisms in budding yeastQ41971919
Crossover homeostasis in yeast meiosisQ41991996
A hierarchical combination of factors shapes the genome-wide topography of yeast meiotic recombination initiationQ42079090
Regulation of meiotic recombination via Mek1-mediated Rad54 phosphorylationQ42088017
Rad51, the lead in mitotic recombinational DNA repair, plays a supporting role in budding yeast meiosisQ42414232
Sister cohesion and structural axis components mediate homolog bias of meiotic recombinationQ42589701
Global analysis of the meiotic crossover landscape.Q43196392
Native/Denaturing two-dimensional DNA electrophoresis and its application to the analysis of recombination intermediatesQ45148757
Probing meiotic recombination decisions.Q51948975
Phosphorylation of the axial element protein Hop1 by Mec1/Tel1 ensures meiotic interhomolog recombination.Q51962360
A synaptonemal complex protein promotes homology-independent centromere coupling.Q52050486
The importance of genetic recombination for fidelity of chromosome pairing in meiosis.Q52096457
DMC1 functions in a Saccharomyces cerevisiae meiotic pathway that is largely independent of the RAD51 pathwayQ33970877
Biochemical Mutants in the Smut Fungus Ustilago Maydis.Q33975198
Genome-wide analysis of heteroduplex DNA in mismatch repair-deficient yeast cells reveals novel properties of meiotic recombination pathwaysQ34042733
Whence meiosis?Q34092590
RTEL-1 enforces meiotic crossover interference and homeostasisQ34102182
The synaptonemal complex shapes the crossover landscape through cooperative assembly, crossover promotion and crossover inhibition during Caenorhabditis elegans meiosisQ34131609
Checkpoint mechanisms: the puppet masters of meiotic prophaseQ34181357
Gene conversion and crossing over along the 405-kb left arm of Saccharomyces cerevisiae chromosome VII.Q34567183
Budding yeast ATM/ATR control meiotic double-strand break (DSB) levels by down-regulating Rec114, an essential component of the DSB-machinery.Q34795521
Analysis of close stable homolog juxtaposition during meiosis in mutants of Saccharomyces cerevisiaeQ34897771
Spo11 and the Formation of DNA Double-Strand Breaks in MeiosisQ35212439
Pch2 modulates chromatid partner choice during meiotic double-strand break repair in Saccharomyces cerevisiae.Q35222734
Drosophila ATM and ATR have distinct activities in the regulation of meiotic DNA damage and repairQ35503860
Meiotic double-strand breaks occur once per pair of (sister) chromatids and, via Mec1/ATR and Tel1/ATM, once per quartet of chromatidsQ35647513
Novel attributes of Hed1 affect dynamics and activity of the Rad51 presynaptic filament during meiotic recombinationQ35668870
Early decision; meiotic crossover interference prior to stable strand exchange and synapsisQ35739105
Homeostatic control of recombination is implemented progressively in mouse meiosis.Q35870791
Bipartite stimulatory action of the Hop2-Mnd1 complex on the Rad51 recombinase.Q35893640
Roles of RecA homologues Rad51 and Dmc1 during meiotic recombinationQ35910251
COSA-1 reveals robust homeostasis and separable licensing and reinforcement steps governing meiotic crossoversQ35919527
Mek1 kinase is regulated to suppress double-strand break repair between sister chromatids during budding yeast meiosisQ35950096
Crossover interferenceQ35994291
BLM ortholog, Sgs1, prevents aberrant crossing-over by suppressing formation of multichromatid joint moleculesQ36082370
Meiotic chromosome behavior in spread preparations of yeastQ36218718
Zip1-induced changes in synaptonemal complex structure and polycomplex assemblyQ36382459
Numerical constraints and feedback control of double-strand breaks in mouse meiosisQ36832176
Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR).Q37058652
The phage mating theory, with lessons for yeast geneticistsQ37270134
A role for centromere pairing in meiotic chromosome segregationQ37480413
Methods for analysis of crossover interference in Saccharomyces cerevisiae.Q37607239
Endonucleolytic processing of covalent protein-linked DNA double-strand breaksQ38322004
Mnd1 is required for meiotic interhomolog repair.Q38341859
Double Holliday junctions are intermediates of DNA break repair.Q39957722
The MRE4 gene encodes a novel protein kinase homologue required for meiotic recombination in Saccharomyces cerevisiaeQ40411739
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectbiasQ742736
homeostatic regulationQ105946076
Hed1p YDR014W-AQ27547371
Recombinase DMC1 YER179WQ27553055
P304page(s)e1003978
P577publication date2013-01-01
P1433published inPLOS GeneticsQ1893441
P1476titleMeiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulation
P478volume9

Reverse relations

cites work (P2860)
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