DNA damage response clamp 9-1-1 promotes assembly of ZMM proteins for formation of crossovers and synaptonemal complex

scientific article published on 3 March 2015

DNA damage response clamp 9-1-1 promotes assembly of ZMM proteins for formation of crossovers and synaptonemal complex is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1242/JCS.161554
P932PMC publication ID4518444
P698PubMed publication ID25736290
P5875ResearchGate publication ID273151996

P2093author name stringAkira Shinohara
Miki Shinohara
Douglas K Bishop
Kayoko Hayashihara
Jennifer T Grubb
P2860cites workFrequent and efficient use of the sister chromatid for DNA double-strand break repair during budding yeast meiosisQ21092719
Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosisQ24336800
Tid1/Rdh54 promotes colocalization of rad51 and dmc1 during meiotic recombinationQ24648825
SUMO modifications control assembly of synaptonemal complex and polycomplex in meiosis of Saccharomyces cerevisiaeQ24681493
Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenanceQ27324367
A new protein complex promoting the assembly of Rad51 filamentsQ27677299
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexesQ27860662
The meiosis-specific zip4 protein regulates crossover distribution by promoting synaptonemal complex formation together with zip2.Q27929737
Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein familyQ27930009
Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexesQ27931495
RecA homologs Dmc1 and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis.Q27932144
Rad52 promotes postinvasion steps of meiotic double-strand-break repairQ27932985
DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progressionQ27933115
Crossover assurance and crossover interference are distinctly regulated by the ZMM proteins during yeast meiosisQ27934346
Differential association of the conserved SUMO ligase Zip3 with meiotic double-strand break sites reveals regional variations in the outcome of meiotic recombinationQ27934547
Gametogenesis in yeast is regulated by a transcriptional cascade dependent on Ndt80.Q27934574
Zip2, a meiosis-specific protein required for the initiation of chromosome synapsisQ27934770
Saccharomyces cerevisiae checkpoint genes MEC1, RAD17 and RAD24 are required for normal meiotic recombination partner choiceQ27935546
Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpointQ27935742
A role for Ddc1 in signaling meiotic double-strand breaks at the pachytene checkpointQ27936045
Pch2 acts through Xrs2 and Tel1/ATM to modulate interhomolog bias and checkpoint function during meiosisQ27936069
Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathwayQ27936249
Saccharomyces cerevisiae recA homologues RAD51 and DMC1 have both distinct and overlapping roles in meiotic recombinationQ27936736
Crossover/noncrossover differentiation, synaptonemal complex formation, and regulatory surveillance at the leptotene/zygotene transition of meiosisQ27936900
Cyclin‐dependent kinase promotes formation of the synaptonemal complex in yeast meiosisQ27937782
Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination.Q27938325
In vivo assembly and disassembly of Rad51 and Rad52 complexes during double-strand break repairQ27939283
Zip3 provides a link between recombination enzymes and synaptonemal complex proteinsQ27939710
Meiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulationQ27940335
Differential timing and control of noncrossover and crossover recombination during meiosisQ28207440
Stimulation by Rad52 of yeast Rad51-mediated recombinationQ28260489
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpointsQ28266170
hMSH4-hMSH5 recognizes Holliday Junctions and forms a meiosis-specific sliding clamp that embraces homologous chromosomesQ28276445
Homologue engagement controls meiotic DNA break number and distributionQ28658207
Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombinationQ29615272
ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsisQ29618281
The single-end invasion: an asymmetric intermediate at the double-strand break to double-holliday junction transition of meiotic recombinationQ29618523
Meiotic chromosomes: integrating structure and functionQ29618524
Mechanism and control of meiotic recombination initiationQ29618789
The logic and mechanism of homologous recombination partner choiceQ33724834
Synaptonemal complex formation and meiotic checkpoint signaling are linked to the lateral element protein Red1.Q33953047
Regulation of homologous recombination in eukaryotesQ33966065
Checkpoint mechanisms: the puppet masters of meiotic prophaseQ34181357
The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiaeQ36237437
Checking your breaks: surveillance mechanisms of meiotic recombinationQ36424799
Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR).Q37058652
The meiotic recombination checkpoint is regulated by checkpoint rad+ genes in fission yeastQ39647364
The mitotic DNA damage checkpoint proteins Rad17 and Rad24 are required for repair of double-strand breaks during meiosis in yeastQ41822890
A multipurpose fusion tag derived from an unstructured and hyperacidic region of the amyloid precursor proteinQ42094166
Crossover Interference in Saccharomyces cerevisiae Requires a TID1/RDH54- and DMC1-Dependent PathwayQ42123510
Sister cohesion and structural axis components mediate homolog bias of meiotic recombinationQ42589701
A novel multi-purpose cassette for repeated integrative epitope tagging of genes in Saccharomyces cerevisiaeQ47868610
Harnessing homologous recombination in vitro to generate recombinant DNA via SLIC.Q51066780
Phosphorylation of the axial element protein Hop1 by Mec1/Tel1 ensures meiotic interhomolog recombination.Q51962360
A synaptonemal complex protein promotes homology-independent centromere coupling.Q52050486
Identification of double Holliday junctions as intermediates in meiotic recombination.Q54599520
A meiotic recombination checkpoint controlled by mitotic checkpoint genesQ59098626
Identification of joint molecules that form frequently between homologs but rarely between sister chromatids during yeast meiosisQ64389750
MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repairQ71919357
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectDNA damageQ5205747
P304page(s)1494-1506
P577publication date2015-03-03
P1433published inJournal of Cell ScienceQ1524177
P1476titleDNA damage response clamp 9-1-1 promotes assembly of ZMM proteins for formation of crossovers and synaptonemal complex
P478volume128

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cites work (P2860)
Q52361832A compartmentalized signaling network mediates crossover control in meiosis.
Q27932605Budding Yeast SLX4 Contributes to the Appropriate Distribution of Crossovers and Meiotic Double-Strand Break Formation on Bivalents During Meiosis
Q92901769Crossover recombination and synapsis are linked by adjacent regions within the N terminus of the Zip1 synaptonemal complex protein
Q90616013Distinct Functions in Regulation of Meiotic Crossovers for DNA Damage Response Clamp Loader Rad24(Rad17) and Mec1(ATR) Kinase
Q36026803Identification of Putative Mek1 Substrates during Meiosis in Saccharomyces cerevisiae Using Quantitative Phosphoproteomics
Q37401054Meiotic prophase roles of Rec8 in crossover recombination and chromosome structure
Q58694062OsRAD17 Is Required for Meiotic Double-Strand Break Repair and Plays a Redundant Role With OsZIP4 in Synaptonemal Complex Assembly
Q35872885Phosphorylation of the Synaptonemal Complex Protein Zip1 Regulates the Crossover/Noncrossover Decision during Yeast Meiosis
Q38824610Regulating the construction and demolition of the synaptonemal complex.
Q48117756The Exonuclease Homolog OsRAD1 Promotes Accurate Meiotic Double-Strand Break Repair by Suppressing Nonhomologous End Joining.
Q28818150The synaptonemal complex has liquid crystalline properties and spatially regulates meiotic recombination factors

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