| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Brigitte Schlegelberger | Q916643 |
| Thomas Illig | Q28039315 | ||
| Maximilian Schieck | Q37837856 | ||
| P2093 | author name string | Doris Steinemann | |
| Tim Ripperger | |||
| Judith Penkert | |||
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| MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer | Q36938409 | ||
| BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival | Q37055527 | ||
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| Bulk pancreatic cancer cells can convert into cancer stem cells(CSCs) in vitro and 2 compounds can target these CSCs | Q37091938 | ||
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| p53 regulates mitochondrial respiration | Q28242400 | ||
| Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis | Q28242612 | ||
| Environmental epigenetics and its implication on disease risk and health outcomes | Q28385993 | ||
| Oxidative stress and autophagy: the clash between damage and metabolic needs | Q28387805 | ||
| BRCA1 and Oxidative Stress | Q28388921 | ||
| AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 | Q28506431 | ||
| Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention | Q28708831 | ||
| IDH mutation impairs histone demethylation and results in a block to cell differentiation | Q29305058 | ||
| Triple-Negative Breast Cancer | Q29391607 | ||
| Drug repositioning: identifying and developing new uses for existing drugs | Q29614779 | ||
| Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain | Q29615210 | ||
| Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation | Q29615366 | ||
| Mitochondria and cancer | Q29616610 | ||
| Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction | Q29616653 | ||
| Oxidative stress, inflammation, and cancer: how are they linked? | Q29616835 | ||
| c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism | Q29617213 | ||
| Akt stimulates aerobic glycolysis in cancer cells | Q29619301 | ||
| Glutathione participates in the modulation of starvation-induced autophagy in carcinoma cells | Q30531825 | ||
| MRS-based Metabolomics in Cancer Research | Q30842175 | ||
| Surfaced-enhanced laser desorption/ionization time-of-flight (SELDI-TOF) differentiation of serum protein profiles of BRCA-1 and sporadic breast cancer. | Q31114474 | ||
| Changes in the mouse estrus cycle in response to BRCA1 inactivation suggest a potential link between risk factors for familial and sporadic ovarian cancer | Q33584787 | ||
| Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis | Q33597162 | ||
| Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer | Q33604129 | ||
| Tumor heterogeneity: causes and consequences | Q33624298 | ||
| The IGF Hormonal Network in Endometrial Cancer: Functions, Regulation, and Targeting Approaches | Q33658023 | ||
| COX-2 activation is associated with Akt phosphorylation and poor survival in ER-negative, HER2-positive breast cancer | Q33747000 | ||
| An atlas of genetic influences on human blood metabolites | Q33780813 | ||
| BRCA1 induces major energetic metabolism reprogramming in breast cancer cells. | Q33882790 | ||
| Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors | Q33967878 | ||
| An HR-MAS MR metabolomics study on breast tissues obtained with core needle biopsy | Q34058288 | ||
| Human metabolic correlates of body mass index | Q34218551 | ||
| Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group. | Q51586347 | ||
| Glutamate enrichment as new diagnostic opportunity in breast cancer. | Q52874359 | ||
| Metformin synergizes 5-fluorouracil, epirubicin, and cyclophosphamide (FEC) combination therapy through impairing intracellular ATP production and DNA repair in breast cancer stem cells. | Q53378831 | ||
| Addition of 2-deoxyglucose enhances growth inhibition but reverses acidification in colon cancer cells treated with phenformin. | Q54607164 | ||
| A serum nuclear magnetic resonance-based metabolomic signature of advanced metastatic human breast cancer | Q61780836 | ||
| A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I | Q73274526 | ||
| Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer | Q77601963 | ||
| Intratumoral IGF-I protein expression is selectively upregulated in breast cancer patients with BRCA1/2 mutations | Q80112552 | ||
| An efficient and robust fatty acid profiling method for plasma metabolomic studies by gas chromatography-mass spectrometry | Q86379849 | ||
| Prevalence of mutations in a panel of breast cancer susceptibility genes in BRCA1/2-negative patients with early-onset breast cancer. | Q35736188 | ||
| Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: treating cancer like an infectious disease | Q35741510 | ||
| Metformin- A Promising Agent for Chemoprevention in BRCA1 Carriers | Q35761000 | ||
| Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling | Q35793332 | ||
| Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers | Q35911155 | ||
| DNA repair genes implicated in triple negative familial non-BRCA1/2 breast cancer predisposition | Q35993095 | ||
| Oxidative stress promotes myofibroblast differentiation and tumour spreading | Q36039273 | ||
| BRCA1 negatively regulates IGF-1 expression through an estrogen-responsive element-like site | Q36072014 | ||
| Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition | Q36169778 | ||
| Hyperactivation of 4E-binding protein 1 as a mediator of biguanide-induced cytotoxicity during glucose deprivation | Q39383162 | ||
| Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors. | Q39425252 | ||
| The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells | Q39705415 | ||
| Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells | Q39730167 | ||
| Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells | Q39743196 | ||
| Elevated insulin-like growth factor-I receptor (IGF-IR) levels in primary breast tumors associated with BRCA1 mutations | Q40086113 | ||
| Insulin-like growth factor-I controls BRCA1 gene expression through activation of transcription factor Sp1. | Q40156648 | ||
| Regulation of the estrogen-inducible gene expression profile by the breast cancer susceptibility gene BRCA1. | Q40473863 | ||
| BRCA1 suppresses insulin-like growth factor-I receptor promoter activity: potential interaction between BRCA1 and Sp1. | Q40893407 | ||
| BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential | Q40907759 | ||
| Serum metabolomic profiles evaluated after surgery may identify patients with oestrogen receptor negative early breast cancer at increased risk of disease recurrence. Results from a retrospective study | Q41135871 | ||
| Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer | Q42450903 | ||
| Prostaglandin E2 inhibits p53 in human breast adipose stromal cells: a novel mechanism for the regulation of aromatase in obesity and breast cancer | Q42472158 | ||
| Epigenetic Inactivation of BRCA1 Through Promoter Hypermethylation and Its Clinical Importance in Triple-Negative Breast Cancer | Q42480009 | ||
| The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells | Q42756576 | ||
| The cyclooxygenase-2 inhibitor, celecoxib, prevents the development of mammary tumors in Her-2/neu mice. | Q44705034 | ||
| Nrf2 prevents initiation but accelerates progression through the Kras signaling pathway during lung carcinogenesis | Q44825975 | ||
| Integration of metabolomics and expression of glycerol-3-phosphate acyltransferase (GPAM) in breast cancer-link to patient survival, hormone receptor status, and metabolic profiling | Q45345524 | ||
| The sex hormone system in carriers of BRCA1/2 mutations: a case-control study. | Q45802281 | ||
| Comparative metabolomics of estrogen receptor positive and estrogen receptor negative breast cancer: alterations in glutamine and beta-alanine metabolism | Q46743426 | ||
| In vivo intracerebral administration of L-2-hydroxyglutaric acid provokes oxidative stress and histopathological alterations in striatum and cerebellum of adolescent rats. | Q46769721 | ||
| Disruption of redox homeostasis and histopathological alterations caused by in vivo intrastriatal administration of D-2-hydroxyglutaric acid to young rats. | Q46864163 | ||
| Effects of metformin treatment on erythrocyte insulin binding in normal weight subjects, in obese non diabetic subjects, in type 1 and type 2 diabetic patients. | Q47206598 | ||
| Environment-mediated drug resistance: a major contributor to minimal residual disease | Q37582773 | ||
| Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target | Q37596851 | ||
| Metformin inhibits androgen-induced IGF-IR up-regulation in prostate cancer cells by disrupting membrane-initiated androgen signaling | Q37648017 | ||
| Estrogen controls the survival of BRCA1-deficient cells via a PI3K-NRF2-regulated pathway | Q37674501 | ||
| Rethinking the Warburg effect with Myc micromanaging glutamine metabolism | Q37677940 | ||
| MYC and mitochondrial biogenesis | Q37717928 | ||
| Glutamine: pleiotropic roles in tumor growth and stress resistance | Q37837590 | ||
| Parkinson's disease and cancer: two wars, one front | Q37948585 | ||
| NRF2 and p53: Januses in cancer? | Q38061832 | ||
| IGF-1 and BRCA1 signalling pathways in familial cancer | Q38062611 | ||
| Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis | Q38324237 | ||
| Caveolae and signalling in cancer | Q38388286 | ||
| Neoadjuvant Window Studies of Metformin and Biomarker Development for Drugs Targeting Cancer Metabolism | Q38524569 | ||
| Metabolic dysregulation in monogenic disorders and cancer - finding method in madness | Q38530400 | ||
| Metabolomics Biomarkers for Breast Cancer | Q38578709 | ||
| Enhancing doxorubicin efficacy through inhibition of aspartate transaminase in triple-negative breast cancer cells | Q38777529 | ||
| Combined Use of Metformin and Everolimus Is Synergistic in the Treatment of Breast Cancer Cells | Q38836764 | ||
| Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells. | Q38847446 | ||
| Metabolic profiling of breast cancer: Differences in central metabolism between subtypes of breast cancer cell lines | Q38848583 | ||
| BM-MSCs promote prostate cancer progression via the conversion of normal fibroblasts to cancer-associated fibroblasts | Q38861688 | ||
| Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells | Q38862527 | ||
| Dual effect of metformin on growth inhibition and oestradiol production in breast cancer cells. | Q38906009 | ||
| Cigarette smoking behaviour and blood metabolomics | Q38925681 | ||
| Prospective multicenter cohort study of estrogen and insulin-like growth factor system in BRCA mutation carriers | Q39003013 | ||
| Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer | Q39024340 | ||
| In vivo HIF-mediated reductive carboxylation is regulated by citrate levels and sensitizes VHL-deficient cells to glutamine deprivation | Q39030433 | ||
| BRCA1 deficiency induces protective autophagy to mitigate stress and provides a mechanism for BRCA1 haploinsufficiency in tumorigenesis. | Q39038292 | ||
| Inversed relationship between CD44 variant and c-Myc due to oxidative stress-induced canonical Wnt activation. | Q39044097 | ||
| Nrf2 is associated with the regulation of basal transcription activity of the BRCA1 gene. | Q39204033 | ||
| Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell. | Q39335846 | ||
| Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC. | Q39340562 | ||
| Metformin and the mTOR inhibitor everolimus (RAD001) sensitize breast cancer cells to the cytotoxic effect of chemotherapeutic drugs in vitro. | Q39346958 | ||
| Mechanisms by which low glucose enhances the cytotoxicity of metformin to cancer cells both in vitro and in vivo | Q34257480 | ||
| A joint analysis of metabolomics and genetics of breast cancer | Q34296486 | ||
| Remodeling of central metabolism in invasive breast cancer compared to normal breast tissue - a GC-TOFMS based metabolomics study | Q34348061 | ||
| MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer | Q34357796 | ||
| Early Detection of Recurrent Breast Cancer Using Metabolite Profiling | Q34369288 | ||
| Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair. | Q34477787 | ||
| The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism. | Q34490597 | ||
| Linking diet, physical activity, cardiorespiratory fitness and obesity to serum metabolite networks: findings from a population-based study | Q34499595 | ||
| MYC in breast tumor progression | Q34524915 | ||
| Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study | Q34622940 | ||
| Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells. | Q34645070 | ||
| Mutational profiles in triple-negative breast cancer defined by ultradeep multigene sequencing show high rates of PI3K pathway alterations and clinically relevant entity subgroup specific differences | Q34654793 | ||
| Interaction between IGF-IR and ER induced by E2 and IGF-I | Q34737272 | ||
| Metformin and erlotinib synergize to inhibit basal breast cancer | Q34786488 | ||
| Targeting mitochondrial glutaminase activity inhibits oncogenic transformation | Q34807996 | ||
| The molecular significance of methylated BRCA1 promoter in white blood cells of cancer-free females | Q34894017 | ||
| Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types | Q34899382 | ||
| Urine biomarkers of risk in the molecular etiology of breast cancer. | Q34908964 | ||
| Metabolic characterization of triple negative breast cancer | Q34967995 | ||
| Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer. | Q34999491 | ||
| The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma | Q35013613 | ||
| Antiproliferative and metabolic effects of metformin in a preoperative window clinical trial for endometrial cancer. | Q35084900 | ||
| Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells | Q35103648 | ||
| Metformin enhances tamoxifen-mediated tumor growth inhibition in ER-positive breast carcinoma | Q35115554 | ||
| Estrogen induces c-myc gene expression via an upstream enhancer activated by the estrogen receptor and the AP-1 transcription factor | Q35193155 | ||
| Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-dependent and PI3K pathway-independent mechanisms | Q35204583 | ||
| PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis | Q35217174 | ||
| Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function | Q35223050 | ||
| Cross-talk between ER and HER2 regulates c-MYC-mediated glutamine metabolism in aromatase inhibitor resistant breast cancer cells. | Q35235623 | ||
| Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models | Q35613319 | ||
| Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability | Q35621293 | ||
| Plasma Proteomic Profiling in Hereditary Breast Cancer Reveals a BRCA1-Specific Signature: Diagnostic and Functional Implications | Q35659498 | ||
| Serum metabolomics analysis reveals changes in signaling lipids in breast cancer patients | Q35693105 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 41 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | breast neoplasm | Q23929670 |
| P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
| P304 | page(s) | 67626-67649 | |
| P577 | publication date | 2016-08-31 | |
| 2016-10-11 | |||
| P1433 | published in | Oncotarget | Q1573155 |
| P1476 | title | On metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancer | |
| P478 | volume | 7 |
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| Q41339597 | The reverse Warburg effect is likely to be an Achilles' heel of cancer that can be exploited for cancer therapy. |
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