Brown adipose tissue activity as a target for the treatment of obesity/insulin resistance

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Brown adipose tissue activity as a target for the treatment of obesity/insulin resistance is …
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review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3389/FPHYS.2015.00004
P3181OpenCitations bibliographic resource ID90849
P932PMC publication ID4311629
P698PubMed publication ID25688211
P5875ResearchGate publication ID272512092

P50authorAnne-Laure PoherQ37373111
P2093author name stringChristelle Veyrat-Durebex
Françoise Rohner-Jeanrenaud
Jordi Altirriba
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Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered metabolic states.Q42813296
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Thyroid hormone effects on whole-body energy homeostasis and tissue-specific fatty acid uptake in vivo.Q43255420
Exercise as a new physiological stimulus for brown adipose tissue activityQ43488931
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Interleukin-6-deficient mice develop mature-onset obesityQ43851625
BMP4 and BMP7 induce the white-to-brown transition of primary human adipose stem cellsQ43911045
Induction of uncoupling protein 1 by central interleukin-6 gene delivery is dependent on sympathetic innervation of brown adipose tissue and underlies one mechanism of body weight reduction in ratsQ44219031
Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humansQ44730563
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Nebivolol induces, via β3 adrenergic receptor, lipolysis, uncoupling protein 1, and reduction of lipid droplet size in human adipocytesQ47198817
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ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes.Q35166610
Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages.Q35663501
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesisQ35755169
Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in miceQ35844663
Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activationQ36196794
Mild cold exposure modulates fibroblast growth factor 21 (FGF21) diurnal rhythm in humans: relationship between FGF21 levels, lipolysis, and cold-induced thermogenesis.Q36508902
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]Q36604703
Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat.Q36758223
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FGF21 regulates metabolism and circadian behavior by acting on the nervous systemQ37161082
Receptor-mediated regional sympathetic nerve activation by leptin.Q37369894
Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposityQ37383979
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Adipose tissue and fetal programming.Q37992001
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The hypothalamus-adipose axis is a key target of developmental programming by maternal nutritional manipulationQ38056405
Bone morphogenic proteins signaling in adipogenesis and energy homeostasisQ38077033
Brown adipose tissue thermogenesis: β3-adrenoreceptors as a potential target for the treatment of obesity in humansQ38109463
Understanding the brown adipocyte as a contributor to energy homeostasisQ38109726
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Browning of white fat: does irisin play a role in humans?Q38208190
The different shades of fat.Q38217767
Does exposure to hyperglycaemia in utero increase the risk of obesity and diabetes in the offspring? A critical reappraisal.Q38266316
Central leptin regulates the UCP1 and ob genes in brown and white adipose tissue via different beta-adrenoceptor subtypesQ38309535
Leptin alters metabolic rates before acquisition of its anorectic effect in developing neonatal miceQ38320718
Effect of age on brown adipose tissue activity in the obese (ob/ob) mouseQ38339279
A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humansQ39421041
Luxuskonsumption, Diet-Induced Thermogenesis and Brown Fat: The Case in FavourQ40144246
Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytesQ40861453
Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones.Q40895648
Hepatic PTEN deficiency improves muscle insulin sensitivity and decreases adiposity in miceQ41733861
Recruited brown adipose tissue as an antiobesity agent in humansQ41890383
Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytesQ41910885
A preadipocyte clonal line from mouse brown adipose tissue. Short- and long-term responses to insulin and beta-adrenergics.Q42201790
Grizzly bears exhibit augmented insulin sensitivity while obese prior to a reversible insulin resistance during hibernationQ42202924
P407language of work or nameEnglishQ1860
P921main subjectinsulin resistanceQ1053470
preproinsulinQ7240673
obesityQ12174
P304page(s)4
P577publication date2015-01-30
P1433published inFrontiers in PhysiologyQ2434141
P1476titleBrown adipose tissue activity as a target for the treatment of obesity/insulin resistance
P478volume6

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