Human connexin31.9, unlike its orthologous protein connexin30.2 in the mouse, is not detectable in the human cardiac conduction system

scientific journal article

Human connexin31.9, unlike its orthologous protein connexin30.2 in the mouse, is not detectable in the human cardiac conduction system is …
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scholarly articleQ13442814

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P356DOI10.1016/J.YJMCC.2008.12.007
P698PubMed publication ID19168070

P50authorEmmanuel DupontQ42387895
Halina DobrzynskiQ44620952
Radoslaw DobrowolskiQ57317159
P2093author name stringKlaus Willecke
Maria M Kreuzberg
Nicholas J Severs
Riyaz Kaba
Marcus Liebermann
Giselle Rowlinson
Sara Segschneider
P2860cites workSomatic mutations in the connexin 40 gene (GJA5) in atrial fibrillationQ24294428
Molecular characterization and functional expression of the human cardiac gap junction channelQ24302133
Molecular cloning, functional expression, and tissue distribution of a novel human gap junction-forming protein, connexin-31.9. Interaction with zona occludens protein-1Q24303543
Molecular cloning of two human cardiac gap junction proteins, connexin40 and connexin45Q24337362
Properties of mouse connexin 30.2 and human connexin 31.9 hemichannels: implications for atrioventricular conduction in the heartQ24548349
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Deletion of connexin45 in mouse retinal neurons disrupts the rod/cone signaling pathway between AII amacrine and ON cone bipolar cells and leads to impaired visual transmissionQ28586045
Functional properties of mouse connexin30.2 expressed in the conduction system of the heartQ28586647
Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient miceQ28593966
Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologuesQ28609865
Computer three-dimensional reconstruction of the atrioventricular nodeQ30486280
Downregulation of immunodetectable connexin43 and decreased gap junction size in the pathogenesis of chronic hibernation in the human left ventricleQ32100784
Chamber-related differences in connexin expression in the human heart.Q33862875
Comparison of connexin 43, 40 and 45 expression patterns in the developing human and mouse hearts.Q34133287
Structural and functional diversity of connexin genes in the mouse and human genomeQ34137753
Immunocytochemical analysis of connexin expression in the healthy and diseased cardiovascular systemQ34141781
Virtual cloning, functional expression, and gating analysis of human connexin31.9.Q34144393
Connexin30.2 containing gap junction channels decelerate impulse propagation through the atrioventricular nodeQ34596202
Gap junction remodeling and cardiac arrhythmogenesis: cause or coincidence?Q34687709
Diversity of connexin expression patterns in the atrioventricular node: vestigial consequence or functional specialization?Q34728775
Gap junction alterations in human cardiac disease.Q35750004
Antisera directed against connexin43 peptides react with a 43-kD protein localized to gap junctions in myocardium and other tissuesQ36220146
Is there a role for remodeled connexins in AF? No simple answersQ36459867
Role of connexins in atrial fibrillationQ36463248
Remodelling of gap junctions and connexin expression in diseased myocardium.Q36870641
The gap junction communication channelQ40974984
Connexins in mammalian heart functionQ41131017
Cardiac malformation in neonatal mice lacking connexin43.Q41358695
Connexin 43 expression delineates two discrete pathways in the human atrioventricular junctionQ41898681
Site of origin and molecular substrate of atrioventricular junctional rhythm in the rabbit heartQ44620905
Connexin45 expression is preferentially associated with the ventricular conduction system in mouse and rat heartQ46229481
Computer three-dimensional reconstruction of the sinoatrial node.Q51978382
Scaling of atrioventricular transmission in mammalian species: an evolutionary riddle!Q52033309
From mouse to whale: a universal scaling relation for the PR Interval of the electrocardiogram of mammals.Q52409596
Atrioventricular conduction in mammalian species: Hemodynamic and electrical scalingQ60183720
Gap junction remodeling and altered connexin43 expression in the failing human heartQ73085637
Altered connexin expression in human congestive heart failureQ73404402
The gap-junctional protein connexin40 is elevated in patients susceptible to postoperative atrial fibrillationQ73426332
Impaired conduction in the bundle branches of mouse hearts lacking the gap junction protein connexin40Q73635736
Electrophysiological features of the mouse sinoatrial node in relation to connexin distributionQ74513784
Connexin45 (alpha 6) expression delineates an extended conduction system in the embryonic and mature rodent heartQ74609476
Up-regulation of connexin45 in heart failureQ79369581
P433issue4
P921main subjectgap junction channel activity involved in cardiac conduction electrical couplingQ21107046
Gap junction protein delta 3Q21113170
P304page(s)553-559
P577publication date2008-12-29
P1433published inJournal of Molecular and Cellular CardiologyQ2061932
P1476titleHuman connexin31.9, unlike its orthologous protein connexin30.2 in the mouse, is not detectable in the human cardiac conduction system
P478volume46

Reverse relations

cites work (P2860)
Q47657524At the Atrioventricular Crossroads: Dual Pathway Electrophysiology in the Atrioventricular Node and its Underlying Heterogeneities.
Q38198336Atrial fibrillation-linked GJA5/connexin40 mutants impaired gap junctions via different mechanisms
Q55228999Authors' Reply: Unravelling the Mysteries of the Human AV Node.
Q36260704Cardiac Cx43, Cx40 and Cx45 co-assembling: involvement of connexins epitopes in formation of hemichannels and Gap junction channels
Q37591571Cardiac connexins and impulse propagation
Q33493274Connexin 30 is expressed in the mouse sino-atrial node and modulates heart rate
Q36958996Connexin diversity in the heart: insights from transgenic mouse models
Q38263987Connexins in the heart.
Q37257847Cx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delay
Q38502124Electrical consequences of cardiac myocyte: fibroblast coupling
Q26850591Gap junctions
Q37639916Improving cardiac gap junction communication as a new antiarrhythmic mechanism: the action of antiarrhythmic peptides
Q34751220Influence of v5/6-His tag on the properties of gap junction channels composed of connexin43, connexin40 or connexin45.
Q53692125Junctional delay, frequency, and direction-dependent uncoupling of human heterotypic Cx45/Cx43 gap junction channels.
Q26771350Mechanisms underlying the cardiac pacemaker: the role of SK4 calcium-activated potassium channels
Q39038606Murine Electrophysiological Models of Cardiac Arrhythmogenesis
Q34994659MyoR modulates cardiac conduction by repressing Gata4.
Q35693797Residual Cx45 and its relationship to Cx43 in murine ventricular myocardium
Q38532371Role of connexins and pannexins in cardiovascular physiology

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