| scholarly article | Q13442814 |
| review article | Q7318358 |
| P6179 | Dimensions Publication ID | 1012015628 |
| P356 | DOI | 10.1038/35080577 |
| P3181 | OpenCitations bibliographic resource ID | 2269659 |
| P698 | PubMed publication ID | 11433361 |
| P2093 | author name string | L D Hurst | |
| A Eyre-Walker | |||
| P2860 | cites work | Initial sequencing and analysis of the human genome | Q21045365 |
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| Mutation rates differ among regions of the mammalian genome | Q24498019 | ||
| Isochores result from mutation not selection | Q24498046 | ||
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| Compositional constraints and genome evolution | Q28290436 | ||
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| The molecular basis of mutations induced by deoxyribonucleoside triphosphate pool imbalances in mammalian cells | Q34498295 | ||
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| Precise switching of DNA replication timing in the GC content transition area in the human major histocompatibility complex. | Q36569378 | ||
| A novel pathway for transversion mutation induced by dCTP misincorporation in a mutator strain of CHO cells | Q36764846 | ||
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| An isochore transition in the NF1 gene region coincides with a switch in the extent of linkage disequilibrium | Q39807260 | ||
| Evidence that both G + C rich and G + C poor isochores are replicated early and late in the cell cycle | Q40421468 | ||
| Correlation between molecular clock ticking, codon usage fidelity of DNA repair, chromosome banding and chromatin compactness in germline cells | Q41458110 | ||
| The elevated GC content at exonic third sites is not evidence against neutralist models of isochore evolution | Q43586352 | ||
| Cytosine deamination plays a primary role in the evolution of mammalian isochores | Q44875348 | ||
| An analysis of the bovine genome by Cs2SO4-Ag density gradient centrifugation | Q45276990 | ||
| The genetic consequences of DNA precursor pool imbalance: sequence analysis of mutations induced by excess thymidine at the hamster aprt locus | Q46283824 | ||
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| Mammalian DNA replication: mutation biases and the mutation rate. | Q52451474 | ||
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| Chromosome localization-dependent compositional bias of point mutations in Alu repetitive sequences. | Q52848459 | ||
| Different base/base mispairs are corrected with different efficiencies and specificities in monkey kidney cells. | Q52868583 | ||
| Covariation of GC content and the silent site substitution rate in rodents: implications for methodology and for the evolution of isochores. | Q52927789 | ||
| Synonymous codon bias is not caused by mutation bias in G+C-rich genes in humans. | Q52931680 | ||
| Densities, length proportions, and other distributional features of repetitive sequences in the human genome estimated from 430 megabases of genomic sequence | Q57234066 | ||
| The gene-richest bands of human chromosomes replicate at the onset of the S-phase | Q57951190 | ||
| Local Rates of Recombination Are Positively Correlated with GC Content in the Human Genome | Q60510887 | ||
| The compositional distribution of coding sequences and DNA molecules in humans and murids | Q67235419 | ||
| The role of DNA replication and isochores in generating mutation and silent substitution rate variance in mammals | Q67594027 | ||
| Correlations between the compositional properties of human genes, codon usage, and amino acid composition of proteins | Q67994906 | ||
| Recombination and mammalian genome evolution | Q70469993 | ||
| Human coding and noncoding DNA: compositional correlations | Q71168152 | ||
| Changes in ribo- and deoxyribonucleoside triphosphate pools within the cell cycle of a synchronized mouse fibroblast cell line | Q71660514 | ||
| Pattern of selective constraint in C. elegans and C. briggsae genomes | Q73039061 | ||
| The correlation of protein hydropathy with the base composition of coding sequences | Q73203504 | ||
| Comparative evolutionary rates of introns and exons in murine rodents | Q73542592 | ||
| Characteristic sequence pattern in the 5- to 20-bp upstream region of primate Alu elements | Q73643695 | ||
| Mutation pattern variation among regions of the primate genome | Q73709520 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 549-55 | |
| P577 | publication date | 2001-07-01 | |
| P1433 | published in | Nature Reviews Genetics | Q1071824 |
| P1476 | title | The evolution of isochores | |
| P478 | volume | 2 |
| Q36208865 | A Novel Type Pathway-Specific Regulator and Dynamic Genome Environments of a Solanapyrone Biosynthesis Gene Cluster in the Fungus Ascochyta rabiei |
| Q36882213 | A Phylogenomic Assessment of Ancient Polyploidy and Genome Evolution across the Poales |
| Q92690745 | A century of bias in genetics and evolution |
| Q34041667 | A comprehensive reference transcriptome resource for the common house spider Parasteatoda tepidariorum |
| Q41977055 | A genomic basis for the evolution of vertebrate transcription factors containing amino Acid runs |
| Q51915507 | A markovian approach for the prediction of mouse isochores. |
| Q34382796 | A new framework for studying the isochore evolution: estimation of the equilibrium GC content based on the temporal mutation rate model |
| Q33530134 | A universal trend of reduced mRNA stability near the translation-initiation site in prokaryotes and eukaryotes |
| Q30393184 | Amino acid composition in endothermic vertebrates is biased in the same direction as in thermophilic prokaryotes |
| Q44764026 | Amino acids runs and genomic compositional biases in vertebrates |
| Q36242543 | An Isochore Framework Underlies Chromatin Architecture. |
| Q35854846 | An analysis of the gene complement of a marsupial, Monodelphis domestica: evolution of lineage-specific genes and giant chromosomes |
| Q24546063 | An isochore map of human chromosomes |
| Q79266821 | An isochore map of the human genome based on the Z curve method |
| Q81007603 | An isochore transition zone in the NF1 gene region is a conserved landmark of chromosome structure and function |
| Q37642080 | Analytical Biases Associated with GC-Content in Molecular Evolution |
| Q30000333 | Ancestral alleles in the human genome based on population sequencing data |
| Q30482794 | Assignment of isochores for all completely sequenced vertebrate genomes using a consensus |
| Q28202367 | Base compositions of genes encoding alpha-actin and lactate dehydrogenase-A from differently adapted vertebrates show no temperature-adaptive variation in G + C content |
| Q33279052 | Base-compositional heterogeneity in the RAG1 locus among didelphid marsupials: implications for phylogenetic inference and the evolution of GC content |
| Q37557286 | Bayesian Markov chain Monte Carlo sequence analysis reveals varying neutral substitution patterns in mammalian evolution |
| Q36004666 | Biased clustered substitutions in the human genome: the footprints of male-driven biased gene conversion |
| Q35047548 | Biased gene conversion and GC-content evolution in the coding sequences of reptiles and vertebrates |
| Q24655865 | Both selective and neutral processes drive GC content evolution in the human genome |
| Q57251625 | Can mutation or fixation biases explain the allele frequency distribution of human single nucleotide polymorphisms (SNPs)? |
| Q41934881 | Changing effective population size and the McDonald-Kreitman test |
| Q34382808 | Chromosomal G + C content evolution in yeasts: systematic interspecies differences, and GC-poor troughs at centromeres |
| Q35855816 | Chromosome Architecture and Genome Organization |
| Q46258124 | Codon usage and codon pair patterns in non-grass monocot genomes |
| Q30684148 | Codon usage patterns in Chinese bayberry (Myrica rubra) based on RNA-Seq data |
| Q30478840 | Codon usage patterns in Nematoda: analysis based on over 25 million codons in thirty-two species |
| Q34389299 | Comparative analysis of codon usage bias and codon context patterns between dipteran and hymenopteran sequenced genomes |
| Q37318383 | Comparative genomic study reveals a transition from TA richness in invertebrates to GC richness in vertebrates at CpG flanking sites: an indication for context-dependent mutagenicity of methylated CpG sites |
| Q37322300 | Comparative recombination rates in the rat, mouse, and human genomes |
| Q28763574 | Comparative sequence analyses reveal rapid and divergent evolutionary changes of the WFDC locus in the primate lineage |
| Q24558319 | Comparison of the chicken and turkey genomes reveals a higher rate of nucleotide divergence on microchromosomes than macrochromosomes |
| Q34618898 | Compositional biases and polyalanine runs in humans |
| Q34411619 | Compositional gradients in Gramineae genes |
| Q35031378 | Compositional patterns in the genomes of unicellular eukaryotes |
| Q34309873 | Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence |
| Q24603486 | Contrasting GC-content dynamics across 33 mammalian genomes: relationship with life-history traits and chromosome sizes |
| Q35024015 | Covariation in frequencies of substitution, deletion, transposition, and recombination during eutherian evolution |
| Q39744481 | DNA helix: the importance of being GC-rich |
| Q33719158 | Deciphering heterogeneity in pig genome assembly Sscrofa9 by isochore and isochore-like region analyses |
| Q22065757 | Deterministic mutation rate variation in the human genome |
| Q35794410 | Developmental stage related patterns of codon usage and genomic GC content: searching for evolutionary fingerprints with models of stem cell differentiation |
| Q37695589 | Differentiation-induced replication-timing changes are restricted to AT-rich/long interspersed nuclear element (LINE)-rich isochores |
| Q37538168 | Distinct patterns of simple sequence repeats and GC distribution in intragenic and intergenic regions of primate genomes |
| Q43267755 | Distribution of DNA methylation, CpGs, and CpG islands in human isochores |
| Q35212663 | Distribution of meiotic recombination sites |
| Q34618832 | Duplication-dependent CG suppression of the seed storage protein genes of maize |
| Q28742103 | Dynamic evolution of base composition: causes and consequences in avian phylogenomics |
| Q28654800 | Ecological and evolutionary significance of genomic GC content diversity in monocots |
| Q22122100 | Effector diversification within compartments of the Leptosphaeria maculans genome affected by Repeat-Induced Point mutations |
| Q33654627 | Estimates of the effect of natural selection on protein-coding content |
| Q41903111 | Evidence for deep phylogenetic conservation of exonic splice-related constraints: splice-related skews at exonic ends in the brown alga Ectocarpus are common and resemble those seen in humans. |
| Q24814018 | Evidence for selection on synonymous mutations affecting stability of mRNA secondary structure in mammals |
| Q34713978 | Evidence for stabilizing selection on codon usage in chromosomal rearrangements of Drosophila pseudoobscura. |
| Q36089885 | Evidence of selection for an accessible nucleosomal array in human |
| Q53017853 | Evidence of selectively driven codon usage in rice: implications for GC content evolution of Gramineae genes. |
| Q33654639 | Evidence that localized variation in primate sequence divergence arises from an influence of nucleosome placement on DNA repair. |
| Q64120104 | Evolution of Genomic Base Composition: From Single Cell Microbes to Multicellular Animals |
| Q36052327 | Evolution of gene sequence in response to chromosomal location. |
| Q33265509 | Evolution of proteomes: fundamental signatures and global trends in amino acid compositions |
| Q35145835 | Evolutionary consequences of DNA methylation on the GC content in vertebrate genomes |
| Q33769248 | Evolutionary forces affecting synonymous variations in plant genomes. |
| Q53051252 | Evolutionary genomics: A positive becomes a negative. |
| Q35476330 | Evolutionary patterns of DNA base composition and correlation to polymorphisms in DNA repair systems |
| Q34399488 | Evolutionary rates and gene dispensability associate with replication timing in the archaeon Sulfolobus islandicus |
| Q33883121 | Fast evolution of core promoters in primate genomes |
| Q21145252 | Forces shaping the fastest evolving regions in the human genome |
| Q22122007 | Fundamental concepts in genetics: Genetics and the understanding of selection |
| Q54920383 | GC bias lead to increased small amino acids and random coils of proteins in cold-water fishes. |
| Q37351818 | GC content and recombination: reassessing the causal effects for the Saccharomyces cerevisiae genome |
| Q83921204 | GC content evolution of the human and mouse genomes: insights from the study of processed pseudogenes in regions of different recombination rates |
| Q33384130 | GC content increased at CpG flanking positions of fish genes compared with sea squirt orthologs as a mechanism for reducing impact of DNA methylation |
| Q36119885 | GC-Content of Synonymous Codons Profoundly Influences Amino Acid Usage |
| Q34974317 | GC-Profile: a web-based tool for visualizing and analyzing the variation of GC content in genomic sequences |
| Q42598099 | GC-biased gene conversion and selection affect GC content in the Oryza genus (rice). |
| Q34587185 | GC-biased segregation of noncoding polymorphisms in Drosophila |
| Q85347814 | GC-made protein disorder sheds new light on vertebrate evolution |
| Q37273284 | Gene Evolutionary Trajectories and GC Patterns Driven by Recombination in Zea mays. |
| Q37585028 | Gene conversion in angiosperm genomes with an emphasis on genes duplicated by polyploidization |
| Q34335541 | Gene conversion occurs within the mating-type locus of Cryptococcus neoformans during sexual reproduction |
| Q40877299 | Genes on human chromosome 19 show extreme divergence from the mouse orthologs and a high GC content |
| Q38708379 | Genome Organization and Chromosome Architecture |
| Q34273327 | Genome evolution in filamentous plant pathogens: why bigger can be better |
| Q37241262 | Genome size and GC content evolution of Festuca: ancestral expansion and subsequent reduction |
| Q37421075 | Genome-wide colonization of gene regulatory elements by G4 DNA motifs |
| Q50961941 | Genome-wide copy number profiling using high-density SNP array in chickens. |
| Q37625484 | Genomes as documents of evolutionary history |
| Q28611281 | Genomic Analysis of an Ascomycete Fungus from the Rice Planthopper Reveals How It Adapts to an Endosymbiotic Lifestyle |
| Q33668518 | GroEL dependency affects codon usage--support for a critical role of misfolding in gene evolution |
| Q35458052 | Guanine quadruplexes are formed by specific regions of human transposable elements |
| Q34485607 | Hearing silence: non-neutral evolution at synonymous sites in mammals |
| Q33243412 | High guanine and cytosine content increases mRNA levels in mammalian cells |
| Q47398534 | High mutation rates in human and ape pseudoautosomal genes |
| Q37158110 | High-Throughput Sequencing Reveals Single Nucleotide Variants in Longer-Kernel Bread Wheat |
| Q21145834 | Hotspots of biased nucleotide substitutions in human genes |
| Q42119657 | Hotspots of mutation and breakage in dog and human chromosomes |
| Q35018004 | Human genome replication proceeds through four chromatin states. |
| Q30476270 | Human microRNAs target a functionally distinct population of genes with AT-rich 3' UTRs |
| Q42073649 | Human-specific CpG "beacons" identify loci associated with human-specific traits and disease |
| Q79202075 | Identification of isochore boundaries in the human genome using the technique of wavelet multiresolution analysis |
| Q41043683 | Immunocytological analysis of meiotic recombination in two anole lizards (Squamata, Dactyloidae). |
| Q36808815 | Impact of GC content on gene expression pattern in chicken |
| Q55153017 | Impact of mating systems on patterns of sequence polymorphism in flowering plants. |
| Q33762440 | Impact of replication timing on non-CpG and CpG substitution rates in mammalian genomes |
| Q34994441 | Informatics for unveiling hidden genome signatures |
| Q34135136 | Integrating genomics, bioinformatics, and classical genetics to study the effects of recombination on genome evolution |
| Q44861956 | Interspecific and intragenic differences in codon usage bias among vertebrate myosin heavy-chain genes. |
| Q52710198 | Intronic AT skew is a defendable proxy for germline transcription but does not predict crossing-over or protein evolution rates in Drosophila melanogaster. |
| Q82741662 | Introns form compositional clusters in parallel with the compositional clusters of the coding sequences to which they pertain |
| Q41010776 | IsoFinder: computational prediction of isochores in genome sequences |
| Q39504815 | IsoPlotter(+): A Tool for Studying the Compositional Architecture of Genomes |
| Q52026892 | Isochore chromosome maps of the human genome. |
| Q28307507 | Isochore patterns and gene distributions in fish genomes |
| Q44598570 | Isochore structures in the genome of the plant Arabidopsis thaliana |
| Q28245084 | Isochore structures in the mouse genome |
| Q36247591 | Isochores and tissue-specificity |
| Q28767148 | Isochores exhibit evidence of genes interacting with the large-scale genomic environment |
| Q44240026 | Isochores, GC3 and mutation biases in the human genome |
| Q74083861 | Isochores: dream or reality? |
| Q36001682 | Large homogeneous genome regions (isochores) in soybean [glycine max (L.) merr]. |
| Q52806484 | Large scale variation in the rate of germ-line de novo mutation, base composition, divergence and diversity in humans. |
| Q34354530 | Less is more in mammalian phylogenomics: AT-rich genes minimize tree conflicts and unravel the root of placental mammals |
| Q42136150 | Linking great apes genome evolution across time scales using polymorphism-aware phylogenetic models. |
| Q39690641 | Measurements of genomic GC content in plant genomes with flow cytometry: a test for reliability |
| Q33467737 | Measuring the rates of spontaneous mutation from deep and large-scale polymorphism data |
| Q45786550 | Meiotic recombination strongly influences GC-content evolution in short regions in the mouse genome |
| Q28190897 | Misunderstandings about isochores. Part 1 |
| Q42857437 | Models for the evolution of GC content in asexual fungi Candida albicans and C. dubliniensis |
| Q46269573 | Mutational Biases and GC-Biased Gene Conversion Affect GC Content in the Plastomes of Dendrobium Genus |
| Q33332467 | Mutations of different molecular origins exhibit contrasting patterns of regional substitution rate variation |
| Q24801512 | Noncoding DNA, isochores and gene expression: nucleosome formation potential |
| Q57161881 | Numerous potentially functional but non-genic conserved sequences on human chromosome 21 |
| Q35169862 | Ongoing GC-biased evolution is widespread in the human genome and enriched near recombination hot spots |
| Q33407926 | Partial correlation analysis indicates causal relationships between GC-content, exon density and recombination rate in the human genome |
| Q43415916 | Patterns and evolution of nucleotide landscapes in seed plants |
| Q57228180 | Patterns of Vertebrate Isochore Evolution Revealed by Comparison of Expressed Mammalian, Avian, and Crocodilian Genes |
| Q75316265 | Phylogenetic analysis of vertebrate fibrillar collagen locates the position of zebrafish alpha3(I) and suggests an evolutionary link between collagen alpha chains and hox clusters |
| Q43623113 | Phylogenetic patterns of GC-biased gene conversion in placental mammals and the evolutionary dynamics of recombination landscapes |
| Q36082288 | Phylogenomic analysis of the emergence of GC-rich transcription elements |
| Q50225360 | Plasmodium vivax Biology: Insights Provided by Genomics, Transcriptomics and Proteomics. |
| Q57675399 | Quantifying the Slightly Deleterious Mutation Model of Molecular Evolution |
| Q37208453 | Radial chromatin positioning is shaped by local gene density, not by gene expression |
| Q24805150 | Recombination and base composition: the case of the highly self-fertilizing plant Arabidopsis thaliana |
| Q35076941 | Recombination explains isochores in mammalian genomes |
| Q36397980 | Recombination is associated with the evolution of genome structure and worker behavior in honey bees |
| Q35199917 | Reduced representation genome sequencing suggests low diversity on the sex chromosomes of tonkean macaque monkeys |
| Q25257867 | Regions of extreme synonymous codon selection in mammalian genes |
| Q81384054 | Repeats and correlations in human DNA sequences |
| Q42152783 | Reverse polarization in amino acid and nucleotide substitution patterns between human-mouse orthologs of two compositional extrema |
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| Q22122484 | Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution |
| Q35204488 | Sex chromosomes: how X-Y recombination stops |
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| Q40949205 | Species-specific class I gene expansions formed the telomeric 1 mb of the mouse major histocompatibility complex |
| Q38442406 | Structural organization of human replication timing domains. |
| Q52937994 | Substantial regional variation in substitution rates in the human genome: importance of GC content, gene density, and telomere-specific effects. |
| Q35111424 | Substitution patterns are GC-biased in divergent sequences across the metazoans |
| Q28741528 | Substitution patterns are under different influences in primates and rodents |
| Q48302388 | Substitution rates in the X- and Y-linked genes of the plants, Silene latifolia and S. dioica |
| Q31058303 | Symbiodinium transcriptomes: genome insights into the dinoflagellate symbionts of reef-building corals |
| Q36882197 | The Anolis Lizard Genome: An Amniote Genome without Isochores? |
| Q33973441 | The Anolis lizard genome: an amniote genome without isochores |
| Q33395879 | The GC-heterogeneity of teleost fishes |
| Q64921319 | The Interaction of Natural Selection and GC Skew May Drive the Fast Evolution of a Sand Rat Homeobox Gene. |
| Q39153845 | The Isochores as a Fundamental Level of Genome Structure and Organization: A General Overview |
| Q35134468 | The Plasmodium vivax genome sequencing project |
| Q78617751 | The base composition of the genes is correlated with the secondary structures of the encoded proteins |
| Q35047552 | The bimodal distribution of genic GC content is ancestral to monocot species |
| Q36935355 | The branch-site test of positive selection is surprisingly robust but lacks power under synonymous substitution saturation and variation in GC |
| Q79266826 | The correlation between GC3 and hydropathy in human genes |
| Q28285823 | The decline of isochores in mammals: an assessment of the GC content variation along the mammalian phylogeny |
| Q41940536 | The evolution of isochore patterns in vertebrate genomes |
| Q42534424 | The evolution of isochores: evidence from SNP frequency distributions |
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| Q33332585 | The impact of recombination on nucleotide substitutions in the human genome |
| Q37357996 | The influence of genomic context on mutation patterns in the human genome inferred from rare variants. |
| Q30891556 | The isochore patterns of invertebrate genomes |
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| Q35785915 | The neoselectionist theory of genome evolution |
| Q43003763 | The rate, not the spectrum, of base pair substitutions changes at a GC-content transition in the human NF1 gene region: implications for the evolution of the mammalian genome structure |
| Q60302712 | The short-sequence design of DNA and its involvement in the 3-D structure of the genome |
| Q34049625 | Transcriptome map of mouse isochores. |
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| Q34598376 | Weak selection and recent mutational changes influence polymorphic synonymous mutations in humans |
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| Q47345644 | cDNA-based gene mapping and GC3 profiling in the soft-shelled turtle suggest a chromosomal size-dependent GC bias shared by sauropsids. |
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