| scholarly article | Q13442814 |
| P2093 | author name string | Johji Inazawa | |
| Issei Imoto | |||
| Chen Zhao | |||
| Hisaki Nagai | |||
| Kohichiroh Yasui | |||
| Masakazu Ueda | |||
| Mitsuru Emi | |||
| Shigeki Arii | |||
| P4510 | describes a project that uses | Hep-G2 | Q5731621 |
| Huh-7 | Q27555640 | ||
| C-HC-4 | Q54799760 | ||
| Hep 3B2.1-7 | Q54882746 | ||
| Hep-KANO clone 2 | Q54882795 | ||
| Hep-Tabata | Q54882796 | ||
| HLE | Q54889847 | ||
| HLF | Q54889850 | ||
| Li-7 | Q54902491 | ||
| PLC/PRF/5 | Q54947574 | ||
| SK-HEP-1 | Q54953666 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell line | Q21014462 |
| P304 | page(s) | 1476-84 | |
| P577 | publication date | 2002-06-01 | |
| P1433 | published in | Hepatology | Q15724398 |
| P1476 | title | TFDP1, CUL4A, and CDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas | |
| P478 | volume | 35 |
| Q42459563 | "Cullin 4 makes its mark on chromatin". |
| Q41712580 | A new layer of degradation mechanism for PR-Set7/Set8 during cell cycle |
| Q34043935 | Accelerated hepatocellular carcinoma development in CUL4B transgenic mice |
| Q49607728 | Activation of TNF-α/NF-κB axis enhances CRL4BDCAF11 E3 ligase activity and regulates cell cycle progression in human osteosarcoma cells |
| Q40511836 | Adaptively inferring human transcriptional subnetworks |
| Q38780983 | Amplification and overexpression of SKP2 are associated with metastasis of non-small-cell lung cancers to lymph nodes |
| Q24677312 | Analysis of gene expression changes in relation to toxicity and tumorigenesis in the livers of Big Blue transgenic rats fed comfrey (Symphytum officinale) |
| Q36938591 | Analysis of the mechanisms mediating tumor-specific changes in gene expression in human liver tumors |
| Q40616277 | Association of over-expressed TFDP1 with progression of hepatocellular carcinomas |
| Q39799105 | CD1d gene is a target for a novel amplicon at 1q22-23.1 in human hepatocellular carcinoma |
| Q33682986 | CRL4BDCAF11 E3 ligase targets p21 for degradation to control cell cycle progression in human osteosarcoma cells |
| Q34275804 | CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein |
| Q28508809 | CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis |
| Q33688623 | CUL4A contributes to the biology of basal-like breast tumors through modulation of cell growth and antitumor immune response. |
| Q92151235 | CUL4A expression is associated with tumor stage and prognosis in nasopharyngeal carcinoma |
| Q36305413 | CUL4A facilitates hepatocarcinogenesis by promoting cell cycle progression and epithelial-mesenchymal transition |
| Q37602539 | CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression. |
| Q39034678 | CUL4A is overexpressed in human pituitary adenomas and regulates pituitary tumor cell proliferation |
| Q33759631 | CUL4A overexpression as an independent adverse prognosticator in intrahepatic cholangiocarcinoma |
| Q34581688 | CUL4A overexpression enhances lung tumor growth and sensitizes lung cancer cells to erlotinib via transcriptional regulation of EGFR. |
| Q42176242 | CUL4A promotes cell invasion in gastric cancer by activating the NF-κB signaling pathway |
| Q37609233 | CUL4A ubiquitin ligase: a promising drug target for cancer and other human diseases |
| Q37446146 | Characterization of nuclear localization signal in the N terminus of CUL4B and its essential role in cyclin E degradation and cell cycle progression. |
| Q30488297 | Clinical implication of recurrent copy number alterations in hepatocellular carcinoma and putative oncogenes in recurrent gains on 1q. |
| Q33627191 | Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely candidate target genes. |
| Q53537545 | Control of cell proliferation via elevated NEDD8 conjugation in oral squamous cell carcinoma |
| Q54322037 | Copy number aberrations in combined hepatocellular carcinoma and cholangiocarcinoma |
| Q61799893 | Cul4 E3 ubiquitin ligase regulates ovarian cancer drug resistance by targeting the antiapoptotic protein BIRC3 |
| Q34520002 | Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosome |
| Q35971585 | Cul4A is an oncogene in malignant pleural mesothelioma |
| Q34162380 | Cul4A is essential for spermatogenesis and male fertility |
| Q28593134 | Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis |
| Q36125375 | Cul4A overexpression associated with Gli1 expression in malignant pleural mesothelioma |
| Q28593723 | Cul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesis |
| Q86410521 | Cullin 4A and 4B ubiquitin ligases interact with γ-tubulin and induce its polyubiquitination |
| Q37742985 | Cullin 4A is associated with epithelial to mesenchymal transition and poor prognosis in perihilar cholangiocarcinoma |
| Q43527311 | Cullin 4B is a novel prognostic marker that correlates with colon cancer progression and pathogenesis |
| Q26822657 | Cullin family proteins and tumorigenesis: genetic association and molecular mechanisms |
| Q34606093 | Cullin-4A·DNA damage-binding protein 1 E3 ligase complex targets tumor suppressor RASSF1A for degradation during mitosis |
| Q28237912 | Cullin4A and cullin4B are interchangeable for HIV Vpr and Vpx action through the CRL4 ubiquitin ligase complex |
| Q34365216 | Cullins and Cancer |
| Q53690290 | DNA Damage Inducible Transcript 4 Gene: The Switch of the Metabolism as Potential Target in Cancer |
| Q34299011 | De Novo DNA Methyltransferase DNMT3b Interacts with NEDD8-modified Proteins |
| Q28213364 | Differentially regulated genes as putative targets of amplifications at 20q in ovarian cancers |
| Q28086765 | Distinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4B |
| Q38726208 | Dysregulation of CUL4A and CUL4B Ubiquitin Ligases in Lung Cancer |
| Q28086796 | Dysregulation of ubiquitin ligases in cancer |
| Q34815903 | Dystonia, facial dysmorphism, intellectual disability and breast cancer associated with a chromosome 13q34 duplication and overexpression of TFDP1: case report |
| Q39031671 | E3 ubiquitin ligase Cullin4B mediated polyubiquitination of p53 for its degradation |
| Q35082710 | E3 ubiquitin ligases as cancer targets and biomarkers |
| Q39923417 | ERK5 is a target for gene amplification at 17p11 and promotes cell growth in hepatocellular carcinoma by regulating mitotic entry |
| Q34209982 | Elevated expression levels of NCOA3, TOP1, and TFAP2C in breast tumors as predictors of poor prognosis. |
| Q38182833 | Exploration of liver cancer genomes |
| Q35589239 | Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses |
| Q99590098 | Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo |
| Q34580906 | Hepatitis B virus HBx protein interactions with the ubiquitin proteasome system |
| Q59355524 | Hepatocellular Carcinoma: Causes, Mechanism of Progression and Biomarkers |
| Q31142505 | Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data |
| Q24803258 | Identification of frequent cytogenetic aberrations in hepatocellular carcinoma using gene-expression microarray data |
| Q34199555 | Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8A1 and human ch13q34. |
| Q35207086 | Inactivating UBE2M impacts the DNA damage response and genome integrity involving multiple cullin ligases |
| Q33673563 | Integrative analysis of multi-omics data reveals distinct impacts of DDB1-CUL4 associated factors in human lung adenocarcinomas |
| Q51802432 | Integrative approach for prioritizing cancer genes in sporadic colon cancer. |
| Q90277936 | Investigation of the role of cullin 4A overexpression in human liver cancer |
| Q54656884 | Involvement of cyclin D3 in liver metastasis of colorectal cancer, revealed by genome-wide copy-number analysis. |
| Q40507438 | Involvement of overexpressed wild-type BRAF in the growth of malignant melanoma cell lines. |
| Q37056992 | Knockdown of cullin 4A inhibits growth and increases chemosensitivity in lung cancer cells |
| Q33988959 | Long intergenic non-coding RNAs (LincRNAs) identified by RNA-seq in breast cancer |
| Q33855635 | Lung tumourigenesis in a conditional Cul4A transgenic mouse model. |
| Q49396643 | MicroRNA-300 Regulates the Ubiquitination of PTEN through the CRL4BDCAF13 E3 Ligase in Osteosarcoma Cells |
| Q40195859 | Molecular characterization of human multiple myeloma cell lines by integrative genomics: insights into the biology of the disease. |
| Q35112054 | Nanostring-based multigene assay to predict recurrence for gastric cancer patients after surgery |
| Q36014392 | Oncocytic change in pleomorphic adenoma: molecular evidence in support of an origin in neoplastic cells |
| Q36833979 | Oncogenic CUL4A determines the response to thalidomide treatment in prostate cancer |
| Q35691547 | Oncogenic aberrations of cullin-dependent ubiquitin ligases |
| Q28212534 | PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas |
| Q35971298 | Pathogenic Role of the CRL4 Ubiquitin Ligase in Human Disease |
| Q38309560 | Positional expression profiling indicates candidate genes in deletion hotspots of hepatocellular carcinoma |
| Q37249694 | Proliferation defects and genome instability in cells lacking Cul4A. |
| Q28390295 | REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase |
| Q38052131 | Radiosensitization of Cancer Cells by Inactivation of Cullin-RING E3 Ubiquitin Ligases |
| Q35873406 | Recurrent Amplification at 13q34 Targets at CUL4A, IRS2, and TFDP1 As an Independent Adverse Prognosticator in Intrahepatic Cholangiocarcinoma |
| Q80531098 | Reduced expression of cell cycle regulator p18(INK4C) in human hepatocellular carcinoma |
| Q64109261 | Regulation of liver receptor homologue-1 by DDB2 E3 ligase activity is critical for hepatic glucose metabolism |
| Q35880315 | SCF E3 Ubiquitin Ligases as Anticancer Targets |
| Q42801709 | Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization |
| Q39084628 | Simultaneous recovery of dual pathways for ammonia metabolism do not improve further detoxification of ammonia in HepG2 cells |
| Q35651812 | Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy |
| Q41351477 | Suppression of CUL4A attenuates TGF-β1-induced epithelial-to-mesenchymal transition in breast cancer cells |
| Q34353149 | Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage |
| Q37354000 | The CUL4A ubiquitin ligase is a potential therapeutic target in skin cancer and other malignancies |
| Q90943372 | The anaphase-promoting complex: A key mitotic regulator associated with somatic mutations occurring in cancer |
| Q34147948 | The emerging role of the COP9 signalosome in cancer |
| Q27003050 | The genetic and epigenetic alterations in human hepatocellular carcinoma: a recent update |
| Q26783814 | The role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implications |
| Q38178169 | The role and therapeutic implications of RING-finger E3 ubiquitin ligases in hepatocellular carcinoma |
| Q28578733 | X-Linked Mental Retardation Gene CUL4B Targets Ubiquitylation of H3K4 Methyltransferase Component WDR5 and Regulates Neuronal Gene Expression |
| Q36994782 | ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21WAF1 |
| Q47073820 | Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a expression. |
| Q38668774 | miR-181a-2 downregulates the E3 ubiquitin ligase CUL4A transcript and promotes cell proliferation |
| Q30436015 | p21 in cancer: intricate networks and multiple activities |
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