| scholarly article | Q13442814 |
| P50 | author | Gregory Hannon | Q55101059 |
| Niraj H Tolia | Q55175593 | ||
| Leemor Joshua-Tor | Q25358110 | ||
| P2093 | author name string | Fabiola V Rivas | |
| Jidong Liu | |||
| Ji-Joon Song | |||
| Juan P Aragon | |||
| P2860 | cites work | Recombining the structures of HIV integrase, RuvC and RNase H. | Q40516667 |
| Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity | Q40620002 | ||
| RISC is a 5' phosphomonoester-producing RNA endonuclease | Q40840939 | ||
| Molecular basis of double-stranded RNA-protein interactions: structure of a dsRNA-binding domain complexed with dsRNA. | Q41877792 | ||
| In vitro analysis of RNA interference in Drosophila melanogaster. | Q52608589 | ||
| Catalysis by Escherichia coli ribonuclease HI is facilitated by a phosphate group of the substrate. | Q54197508 | ||
| Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. | Q55039785 | ||
| Thermal stability of Escherichia coli ribonuclease HI and its active site mutants in the presence and absence of the Mg2+ ion. Proposal of a novel catalytic role for Glu48 | Q71859993 | ||
| RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs | Q77543012 | ||
| Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs | Q24299641 | ||
| A general two-metal-ion mechanism for catalytic RNA | Q24562157 | ||
| A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal | Q24595550 | ||
| Two-metal ion mechanism of RNA cleavage by HIV RNase H and mechanism-based design of selective HIV RNase H inhibitors | Q24611147 | ||
| The structure of the cell cycle protein Cdc14 reveals a proline-directed protein phosphatase | Q24681613 | ||
| Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination | Q26778405 | ||
| Processing of X-ray diffraction data collected in oscillation mode | Q26778468 | ||
| Crystal structure of a phospholipase D family member | Q27617507 | ||
| Three-dimensional structure of the Tn5 synaptic complex transposition intermediate | Q27625249 | ||
| Co-crystal of Escherichia coli RNase HI with Mn2+ ions reveals two divalent metals bound in the active site | Q27628463 | ||
| Structural biochemistry of a type 2 RNase H: RNA primer recognition and removal during DNA replication | Q27630668 | ||
| Two-metal active site binding of a Tn5 transposase synaptic complex | Q27638356 | ||
| Evidence for "unseen" transposase--DNA contacts | Q27639739 | ||
| The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes | Q27642580 | ||
| Crystal structure of Escherichia coli RNase HI in complex with Mg2+ at 2.8 A resolution: proof for a single Mg(2+)-binding site | Q27730949 | ||
| Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity | Q27740341 | ||
| Raster3D Version 2.0. A program for photorealistic molecular graphics | Q27860485 | ||
| Argonaute2 is the catalytic engine of mammalian RNAi | Q27860545 | ||
| An extensively modified version of MolScript that includes greatly enhanced coloring capabilities | Q27860594 | ||
| RNA interference is mediated by 21- and 22-nucleotide RNAs | Q27860764 | ||
| RNA interference | Q28131798 | ||
| Single-stranded antisense siRNAs guide target RNA cleavage in RNAi | Q28201784 | ||
| Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain | Q28262499 | ||
| Mechanisms of gene silencing by double-stranded RNA | Q28282560 | ||
| Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate | Q28365532 | ||
| An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells | Q29547714 | ||
| Crystal structure of Argonaute and its implications for RISC slicer activity | Q29614980 | ||
| Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism | Q29616775 | ||
| ATP requirements and small interfering RNA structure in the RNA interference pathway | Q29618384 | ||
| Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways | Q29618467 | ||
| Electron-density map interpretation | Q29620698 | ||
| Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis | Q29642793 | ||
| 13 Laser cross-linking of protein-nucleic acid complexes | Q33297276 | ||
| RISC assembly defects in the Drosophila RNAi mutant armitage. | Q33976808 | ||
| The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans | Q34137901 | ||
| Tn5 transposase active site mutations suggest position of donor backbone DNA in synaptic complex | Q34158349 | ||
| The RNA-induced silencing complex is a Mg2+-dependent endonuclease. | Q34317673 | ||
| A protein sensor for siRNA asymmetry | Q34369235 | ||
| Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase | Q34577497 | ||
| Structure/function insights into Tn5 transposition. | Q35753206 | ||
| A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins | Q35804357 | ||
| Kinetic analysis of the RNAi enzyme complex | Q38340658 | ||
| Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain | Q38340880 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 340-9 | |
| P577 | publication date | 2005-04-01 | |
| P1433 | published in | Nature Structural & Molecular Biology | Q1071739 |
| P1476 | title | Purified Argonaute2 and an siRNA form recombinant human RISC | |
| P478 | volume | 12 |
| Q100633215 | 21-nt phasiRNAs direct target mRNA cleavage in rice male germ cells |
| Q34628588 | 5'-Serial Analysis of Gene Expression studies reveal a transcriptomic switch during fruiting body development in Coprinopsis cinerea |
| Q92886158 | A Novel Method to Silence Genes in Cryptosporidium |
| Q52859629 | A Rapid and Versatile Assay for Ago2-Mediated Cleavage by Using Branched Rolling Circle Amplification. |
| Q35914960 | A Systematic Genetic Screen to Dissect the MicroRNA Pathway in Drosophila |
| Q42059907 | A Tetrahymena Hsp90 co-chaperone promotes siRNA loading by ATP-dependent and ATP-independent mechanisms |
| Q36821403 | A bacterial Argonaute with noncanonical guide RNA specificity |
| Q64907610 | A circular transcript of ncx1 gene mediates ischemic myocardial injury by targeting miR-133a-3p. |
| Q35783043 | A complex system of small RNAs in the unicellular green alga Chlamydomonas reinhardtii |
| Q28250307 | A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain |
| Q28508177 | A dicer-independent miRNA biogenesis pathway that requires Ago catalysis |
| Q52707405 | A direct role for Hsp90 in pre-RISC formation in Drosophila. |
| Q47224822 | A fungal Argonaute interferes with RNA interference |
| Q37118788 | A genetic screen for components of the mammalian RNA interference pathway in Bloom-deficient mouse embryonic stem cells |
| Q34884054 | A genomewide screen for components of the RNAi pathway in Drosophila cultured cells |
| Q24298937 | A human, ATP-independent, RISC assembly machine fueled by pre-miRNA |
| Q36407767 | A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA. |
| Q26995773 | A prokaryotic twist on argonaute function |
| Q34609180 | A role for human Dicer in pre-RISC loading of siRNAs |
| Q34926596 | A three-dimensional view of the molecular machinery of RNA interference |
| Q90492949 | AGO unchained: Canonical and non-canonical roles of Argonaute proteins in mammals |
| Q33937733 | AGO3 Slicer activity regulates mitochondria-nuage localization of Armitage and piRNA amplification |
| Q46907093 | ARGONAUTE4 is required for resistance to Pseudomonas syringae in Arabidopsis. |
| Q42547632 | ATP modulates siRNA interactions with an endogenous human Dicer complex |
| Q24336545 | ATP-dependent human RISC assembly pathways |
| Q27339381 | Abasic pivot substitution harnesses target specificity of RNA interference |
| Q40329116 | Adenovirus virus-associated RNA is processed to functional interfering RNAs involved in virus production |
| Q36342249 | Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins |
| Q35172243 | An unusual Dicer-like1 protein fuels the RNA interference pathway in Trypanosoma brucei |
| Q40082566 | Analysis of AgoshRNA maturation and loading into Ago2. |
| Q39773875 | Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5'-terminal phosphorylation both in vitro and in vivo. |
| Q36949259 | Analysis of microRNA effector functions in vitro |
| Q59166227 | Analysis of pre-miR-29b binding conditions to amino acids by using a surface plasmon resonance biosensor |
| Q26749350 | Anatomy of RISC: how do small RNAs and chaperones activate Argonaute proteins? |
| Q37784602 | Ancestral roles of small RNAs: an Ago-centric perspective |
| Q41334770 | Antisense tools for functional studies of human Argonaute proteins |
| Q37914065 | Antiviral RNAi: translating science towards therapeutic success |
| Q64065405 | Application of Locked Nucleic Acid Oligonucleotides for siRNA Preclinical Bioanalytics |
| Q36801057 | Applications of RNA interference: current state and prospects for siRNA-based strategies in vivo |
| Q33911803 | Arabidopsis ARGONAUTE1 is an RNA Slicer that selectively recruits microRNAs and short interfering RNAs |
| Q38881648 | Argonaute 2 Binds Directly to tRNA Genes and Promotes Gene Repression in cis. |
| Q89623329 | Argonaute Proteins: From Structure to Function in Development and Pathological Cell Fate Determination |
| Q26767285 | Argonaute and Argonaute-Bound Small RNAs in Stem Cells |
| Q90317374 | Argonaute bypasses cellular obstacles without hindrance during target search |
| Q36678555 | Argonaute divides its RNA guide into domains with distinct functions and RNA-binding properties |
| Q35262586 | Argonaute protein identity and pairing geometry determine cooperativity in mammalian RNA silencing. |
| Q90862548 | Argonaute proteins from human gastrointestinal bacteria catalyze DNA-guided cleavage of single- and double-stranded DNA at 37 °C |
| Q29614714 | Argonaute proteins: key players in RNA silencing |
| Q27008193 | Argonaute-dependent small RNAs derived from single-stranded, non-structured precursors |
| Q36915071 | Argonaute2 expression is post-transcriptionally coupled to microRNA abundance |
| Q39222663 | Argonaute2 promotes tumor metastasis by way of up-regulating focal adhesion kinase expression in hepatocellular carcinoma. |
| Q34007461 | Argonautes confront new small RNAs |
| Q35587931 | Autoantigen La promotes efficient RNAi, antiviral response, and transposon silencing by facilitating multiple-turnover RISC catalysis |
| Q39981448 | Bacterial expression of mouse argonaute 2 for functional and mutational studies. |
| Q42577985 | Binding and cleavage specificities of human Argonaute2. |
| Q33274614 | Biochemical mechanisms of the RNA-induced silencing complex |
| Q92690126 | Biphasic regulation of RNA interference during rotavirus infection by modulation of Argonaute2 |
| Q39753665 | Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease. |
| Q42007110 | Characterization of Argonaute family members in the silkworm, Bombyx mori |
| Q28117846 | Characterization of Novel Ribosome-Associated Endoribonuclease SLFN14 from Rabbit Reticulocytes |
| Q43202812 | Characterization of RNase HII substrate recognition using RNase HII-argonaute chimaeric enzymes from Pyrococcus furiosus |
| Q43103477 | Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway |
| Q34572157 | Cloning and characterization of two Argonaute genes in wheat (Triticum aestivum L.). |
| Q36808619 | Cloning, expression, purification and preliminary crystallographic analysis of the RNase HI domain of the Mycobacterium tuberculosis protein Rv2228c as a maltose-binding protein fusion |
| Q39709748 | Combination of RNA interference and U1 inhibition leads to increased inhibition of gene expression |
| Q35990922 | Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC |
| Q39590574 | Competition between small RNAs: a quantitative view |
| Q39113952 | Competition for RISC binding predicts in vitro potency of siRNA. |
| Q38542396 | Conformational Dynamics of Ago-Mediated Silencing Processes |
| Q38747671 | Conservation of miRNA-mediated silencing mechanisms across 600 million years of animal evolution |
| Q38934556 | Control of the localization and function of a miRNA silencing component TNRC6A by Argonaute protein |
| Q35230532 | Conversion of pre-RISC to holo-RISC by Ago2 during assembly of RNAi complexes |
| Q36656139 | Core RNAi Machinery and Sid1, a Component for Systemic RNAi, in the Hemipteran Insect, Aphis glycines |
| Q91725423 | Cryptosporidium parvum Subtilisin-Like Serine Protease (SUB1) Is Crucial for Parasite Egress from Host Cells |
| Q36399157 | Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage |
| Q59794139 | DNA interference and beyond: structure and functions of prokaryotic Argonaute proteins |
| Q52631018 | DNA-silencing by prokaryotic Argonaute proteins adds a new layer of defence against invading nucleic acids. |
| Q35804603 | Decoding the cardiac message: the 2011 Thomas W. Smith Memorial Lecture |
| Q34402283 | Deep Sequencing Insights in Therapeutic shRNA Processing and siRNA Target Cleavage Precision |
| Q34155348 | Dephosphorylation of tyrosine 393 in argonaute 2 by protein tyrosine phosphatase 1B regulates gene silencing in oncogenic RAS-induced senescence |
| Q37111734 | Design of siRNA Therapeutics from the Molecular Scale |
| Q40356535 | Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency. |
| Q89910193 | Design, mechanism, delivery and therapeutics of canonical and Dicer-substrate siRNA |
| Q33505682 | Designer siRNAs to overcome the challenges from the RNAi pathway. |
| Q34644554 | Designing highly active siRNAs for therapeutic applications. |
| Q36148370 | Dicer-1, but not Loquacious, is critical for assembly of miRNA-induced silencing complexes |
| Q37277394 | Disease-causing allele-specific silencing by RNA interference |
| Q41562514 | Distinct Functions of Argonaute Slicer in siRNA Maturation and Heterochromatin Formation. |
| Q48084508 | Distinct catalytic and non-catalytic roles of ARGONAUTE4 in RNA-directed DNA methylation |
| Q47265155 | Distinct fitness costs associated with the knockdown of RNAi pathway genes in western corn rootworm adults |
| Q84962168 | Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins |
| Q34713186 | Distinguishable in vitro binding mode of monomeric TRBP and dimeric PACT with siRNA |
| Q36665949 | Diversification of the core RNA interference machinery in Chlamydomonas reinhardtii and the role of DCL1 in transposon silencing |
| Q26851994 | Diversity in requirement of genetic and epigenetic factors for centromere function in fungi |
| Q37956594 | Diversity of animal small RNA pathways and their biological utility |
| Q33308302 | Domain motions of Argonaute, the catalytic engine of RNA interference |
| Q37201783 | Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1. |
| Q37094403 | ENDOCYTOSIS PATHWAYS FOR NUCLEIC ACID THERAPEUTICS. |
| Q37667968 | Effect of siRNA terminal mismatches on TRBP and Dicer binding and silencing efficacy. |
| Q39122556 | Effective tumor treatment by VEGF siRNA complexed with hydrophobic poly(amino acid)-modified polyethylenimine |
| Q33627096 | Emergence of chemical biology approaches to the RNAi/miRNA pathway |
| Q37272418 | Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell. |
| Q51111375 | Endocytic Transport of Polyplex and Lipoplex siRNA Vectors in HeLa Cells. |
| Q50290931 | Endonucleolytic RISC hydrolyzes target RNAs |
| Q36783160 | Epigenetics and microRNAs |
| Q34025954 | Existence of a microRNA pathway in anucleate platelets |
| Q37477536 | Expanded RNA-binding activities of mammalian Argonaute 2. |
| Q59798751 | Expansion and Divergence of Argonaute Genes in the Oomycete Genus Phytophthora |
| Q37665372 | Exploring chemical modifications for siRNA therapeutics: a structural and functional outlook |
| Q36768062 | Expression of human ARGONAUTE 2 inhibits endogenous microRNA activity in Arabidopsis |
| Q50743949 | Expression of microRNA machinery proteins in different types of chronic rhinosinusitis. |
| Q37522469 | Expression site silencing and life-cycle progression appear normal in Argonaute1-deficient Trypanosoma brucei. |
| Q58758032 | Farnesylated heat shock protein 40 is a component of membrane-bound RISC in |
| Q34292691 | Flexibility in MuA transposase family protein structures: functional mapping with scanning mutagenesis and sequence alignment of protein homologues |
| Q39931273 | Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells |
| Q39521378 | Fluorescence cross-correlation spectroscopy reveals mechanistic insights into the effect of 2'-O-methyl modified siRNAs in living cells |
| Q37823803 | Form, function, and regulation of ARGONAUTE proteins. |
| Q35670556 | From guide to target: molecular insights into eukaryotic RNA-interference machinery. |
| Q36768065 | Function and localization of microRNAs in mammalian cells |
| Q37275167 | Functional dissection of the human TNRC6 (GW182-related) family of proteins |
| Q30485517 | Functional insight into Maelstrom in the germline piRNA pathway: a unique domain homologous to the DnaQ-H 3'-5' exonuclease, its lineage-specific expansion/loss and evolutionarily active site switch |
| Q33553009 | Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines |
| Q24544354 | Functional replacement of Trypanosoma brucei Argonaute by the human slicer Argonaute2 |
| Q36804113 | Functional small RNAs are generated from select miRNA hairpin loops in flies and mammals |
| Q36740097 | Fundamental differences in the equilibrium considerations for siRNA and antisense oligodeoxynucleotide design |
| Q50050467 | Gene Manipulation with Micro RNAs at Single-Human Cancer Cell |
| Q50610635 | Gene silencing by artificial microRNAs in Chlamydomonas. |
| Q90066109 | Genome-wide analysis of AGO, DCL and RDR gene families reveals RNA-directed DNA methylation is involved in fruit abscission in Citrus sinensis |
| Q33372983 | Genome-wide identification, organization and phylogenetic analysis of Dicer-like, Argonaute and RNA-dependent RNA Polymerase gene families and their expression analysis during reproductive development and stress in rice |
| Q47798058 | Genome-wide screening for components of small interfering RNA (siRNA) and micro-RNA (miRNA) pathways in the brown planthopper, Nilaparvata lugens (Hemiptera: Delphacidae). |
| Q91936714 | Genomic non-redundancy of the mir-183/96/182 cluster and its requirement for hair cell maintenance |
| Q42396273 | Give It AGO: The Search for miRNA-Argonaute Sorting Signals in Arabidopsis thaliana Indicates a Relevance of Sequence Positions Other than the 5'-Position Alone |
| Q37103772 | Highly complementary target RNAs promote release of guide RNAs from human Argonaute2 |
| Q39537230 | How to slice: snapshots of Argonaute in action |
| Q34982175 | Hsp90 regulates the function of argonaute 2 and its recruitment to stress granules and P-bodies |
| Q50670238 | Identification and characterization of Argonaute gene family and meiosis-enriched Argonaute during sporogenesis in maize. |
| Q39771855 | Identification and characterization of Dicer-like, Argonaute and RNA-dependent RNA polymerase gene families in maize |
| Q33223084 | Identification and characterization of small RNAs involved in RNA silencing |
| Q47675158 | Identification of DISE-inducing shRNAs by monitoring cellular responses. |
| Q38935925 | Identification of cell-free microRNAs in the urine of patients with prostate cancer |
| Q37298895 | Identification of microRNAs dysregulated in cellular senescence driven by endogenous genotoxic stress |
| Q35128292 | Identification of microRNAs in the coral Stylophora pistillata |
| Q82939452 | Identification of microRNAs involved in pathogen-associated molecular pattern-triggered plant innate immunity |
| Q24295156 | Identification of novel argonaute-associated proteins |
| Q43735664 | Identification, chromosomal mapping and conserved synteny of porcine Argonaute family of genes. |
| Q29622905 | Illuminating the silence: understanding the structure and function of small RNAs |
| Q37584772 | Improved asymmetry prediction for short interfering RNAs |
| Q33898406 | In Medicago truncatula, water deficit modulates the transcript accumulation of components of small RNA pathways |
| Q36392787 | In vitro binding of single-stranded RNA by human Dicer |
| Q47710169 | In vitro reconstitution of chaperone-mediated human RISC assembly |
| Q24305536 | In vitro reconstitution of the human RISC-loading complex |
| Q35031404 | In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA. |
| Q39442363 | Increased in vivo inhibition of gene expression by combining RNA interference and U1 inhibition. |
| Q37597107 | Inefficient SRP interaction with a nascent chain triggers a mRNA quality control pathway |
| Q24300900 | Interaction of human T‐cell lymphotropic virus type I Rex protein with Dicer suppresses RNAi silencing |
| Q39093941 | Interactions between the non-seed region of siRNA and RNA-binding RLC/RISC proteins, Ago and TRBP, in mammalian cells |
| Q91678692 | LGP2 virus sensor enhances apoptosis by upregulating apoptosis regulatory genes through TRBP-bound miRNAs during viral infection |
| Q59358209 | LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs |
| Q44491304 | Lessons on RNA silencing mechanisms in plants from eukaryotic argonaute structures |
| Q36878503 | Loop-miRs: active microRNAs generated from single-stranded loop regions |
| Q58583775 | Lost in Translation: Ribosome-Associated mRNA and Protein Quality Controls |
| Q42544679 | Manipulating and enhancing the RNAi response |
| Q35693509 | Markov State Models Reveal a Two-Step Mechanism of miRNA Loading into the Human Argonaute Protein: Selective Binding followed by Structural Re-arrangement |
| Q28474948 | Mechanism of microRNA-target interaction: molecular dynamics simulations and thermodynamics analysis |
| Q42544649 | Mechanisms of RNAi: mRNA cleavage fragments may indicate stalled RISC. |
| Q28552698 | Mechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage Properties |
| Q34361781 | Mg2+ effect on argonaute and RNA duplex by molecular dynamics and bioinformatics implications. |
| Q36569914 | MicroRNA biogenesis: regulating the regulators |
| Q36325449 | MicroRNA function: multiple mechanisms for a tiny RNA? |
| Q34389690 | MicroRNA-directed cleavage of targets: mechanism and experimental approaches |
| Q37726449 | MicroRNA-mediated gene silencing |
| Q35016914 | MicroRNAs in gene regulation: when the smallest governs it all |
| Q37069470 | MicroRNAs: biogenesis and molecular functions. |
| Q37276695 | Minimal mechanistic model of siRNA-dependent target RNA slicing by recombinant human Argonaute 2 protein |
| Q39280722 | Mitochondrial miRNAs in diabetes: just the tip of the iceberg |
| Q28854369 | Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing |
| Q64058853 | Modeling the Kinetics of Lipid-Nanoparticle- Mediated Delivery of Multiple siRNAs to Evaluate the Effect on Competition for Ago2 |
| Q34980471 | Molecular cloning and characterisation of SlAGO family in tomato |
| Q36768074 | Molecular mechanism of target RNA transcript recognition by Argonaute-guide complexes |
| Q36915076 | Multiple sensors ensure guide strand selection in human RNAi pathways |
| Q34202641 | Multisubunit RNA polymerases IV and V: purveyors of non-coding RNA for plant gene silencing |
| Q89805527 | Mutual Regulation of RNA Silencing and the IFN Response as an Antiviral Defense System in Mammalian Cells |
| Q27657724 | Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes |
| Q39797171 | Off-target and a portion of target-specific siRNA mediated mRNA degradation is Ago2 'Slicer' independent and can be mediated by Ago1. |
| Q36173624 | On future's doorstep: RNA interference and the pharmacopeia of tomorrow |
| Q24657546 | On the origin and functions of RNA-mediated silencing: from protists to man |
| Q27860822 | Origins and Mechanisms of miRNAs and siRNAs |
| Q37695540 | Overcoming EGFR T790M-based Tyrosine Kinase Inhibitor Resistance with an Allele-specific DNAzyme |
| Q39339350 | Overcoming nonviral gene delivery barriers: perspective and future |
| Q92514685 | Overexpression of OsAGO1b Induces Adaxially Rolled Leaves by Affecting Leaf Abaxial Sclerenchymatous Cell Development in Rice |
| Q27315245 | Overlapping functions of argonaute proteins in patterning and morphogenesis of Drosophila embryos |
| Q28242438 | P68 RNA helicase unwinds the human let-7 microRNA precursor duplex and is required for let-7-directed silencing of gene expression |
| Q93122257 | P7 and P8 proteins of High Plains wheat mosaic virus, a negative-strand RNA virus, employ distinct mechanisms of RNA silencing suppression |
| Q37349054 | PIWI, piRNAs, and germline stem cells: what's the link? |
| Q36928863 | PRMT1 methylates the single Argonaute of Toxoplasma gondii and is important for the recruitment of Tudor nuclease for target RNA cleavage by antisense guide RNA. |
| Q36257307 | Pathways through the small RNA world of plants |
| Q35630176 | PhyloFacts: an online structural phylogenomic encyclopedia for protein functional and structural classification |
| Q28752288 | Plant responses against invasive nucleic acids: RNA silencing and its suppression by plant viral pathogens |
| Q42226340 | Polysome arrest restricts miRNA turnover by preventing exosomal export of miRNA in growth-retarded mammalian cells |
| Q36705865 | Preassembled Single-Stranded RNA-Argonaute Complexes: A Novel Method to Silence Genes in Cryptosporidium |
| Q38778452 | Precise and efficient siRNA design: a key point in competent gene silencing |
| Q28507271 | Precursor microRNA-programmed silencing complex assembly pathways in mammals |
| Q36617803 | Principles and effects of microRNA-mediated post-transcriptional gene regulation. |
| Q45388167 | Production of cucumber mosaic virus RNA5 and its role in recombination |
| Q64945550 | Programmable DNA cleavage by Ago nucleases from mesophilic bacteria Clostridium butyricum and Limnothrix rosea. |
| Q28297652 | Progress towards in vivo use of siRNAs |
| Q28290225 | Prolyl 4-hydroxylation regulates Argonaute 2 stability |
| Q36992495 | Protein interactions and complexes in human microRNA biogenesis and function |
| Q38335603 | Purification and assembly of human Argonaute, Dicer, and TRBP complexes |
| Q42119372 | QIP, a putative exonuclease, interacts with the Neurospora Argonaute protein and facilitates conversion of duplex siRNA into single strands |
| Q30479192 | Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules |
| Q34924393 | RDE-1 slicer activity is required only for passenger-strand cleavage during RNAi in Caenorhabditis elegans |
| Q34589324 | RETRACTED: Secondary siRNAs result from unprimed RNA synthesis and form a distinct class |
| Q37106523 | RISC-target interaction: cleavage and translational suppression |
| Q26771810 | RNA Binding Proteins in the miRNA Pathway |
| Q41876865 | RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3' Nuclease-resistant Mini-hairpin Structure. |
| Q37996957 | RNA biology in a test tube--an overview of in vitro systems/assays |
| Q33695469 | RNA interference in schistosomes: machinery and methodology |
| Q42942942 | RNA silencing and HIV: a hypothesis for the etiology of the severe combined immunodeficiency induced by the virus |
| Q36452676 | RNA silencing gene truncation in the filamentous fungus Aspergillus nidulans |
| Q33227811 | RNA silencing in Chlamydomonas: mechanisms and tools |
| Q36273960 | RNA silencing in Drosophila |
| Q37683091 | RNA silencing: an antiviral mechanism |
| Q28111715 | RNAi factors are present and active in human cell nuclei |
| Q38730724 | RNAi in Plants: An Argonaute-Centered View |
| Q40310761 | RNAi revised--target mRNA-dependent enhancement of gene silencing |
| Q36526551 | Rapid and specific purification of Argonaute-small RNA complexes from crude cell lysates |
| Q37330092 | Rapid, controlled and intensive lentiviral vector-based RNAi |
| Q33776479 | Recognition of siRNA asymmetry by TAR RNA binding protein. |
| Q38799079 | Recombinant pre-miR-29b for Alzheimer´s disease therapeutics |
| Q40074214 | Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells |
| Q35575239 | Regulation of MicroRNA Biogenesis: A miRiad of mechanisms |
| Q38238669 | Regulation of miRNA strand selection: follow the leader? |
| Q36685663 | Regulatory RNAs: future perspectives in diagnosis, prognosis, and individualized therapy |
| Q34928560 | Retroviral integrase superfamily: the structural perspective |
| Q38292975 | Revealing a new activity of the human Dicer DUF283 domain in vitro |
| Q35012254 | Rice MicroRNA effector complexes and targets |
| Q36305658 | Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing |
| Q25257701 | Role of the silkworm argonaute2 homolog gene in double-strand break repair of extrachromosomal DNA |
| Q36199753 | Silence of the transcripts: RNA interference in medicine |
| Q51025093 | Single-Molecule Fluorescence Energy Transfer Assays for the Characterization of Reaction Pathways of miRNA-Argonaute Complex. |
| Q27322573 | Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid Guides |
| Q37593660 | Single-molecule FRET supports the two-state model of Argonaute action. |
| Q47144806 | Site-Specific Modification Using the 2'-Methoxyethyl Group Improves the Specificity and Activity of siRNAs |
| Q27490914 | Six RNA Viruses and Forty-One Hosts: Viral Small RNAs and Modulation of Small RNA Repertoires in Vertebrate and Invertebrate Systems |
| Q36685866 | Slicer and the argonautes |
| Q40648674 | Slicer function of Drosophila Argonautes and its involvement in RISC formation |
| Q28608271 | Slicer-independent mechanism drives small-RNA strand separation during human RISC assembly |
| Q36768201 | Slicing and spreading of heterochromatic silencing by RNA interference |
| Q36274428 | Small RNA asymmetry in RNAi: function in RISC assembly and gene regulation. |
| Q27313784 | Small RNA-Based Antiviral Defense in the Phytopathogenic Fungus Colletotrichum higginsianum |
| Q50482685 | Small interfering RNA-mediated translation repression alters ribosome sensitivity to inhibition by cycloheximide in Chlamydomonas reinhardtii. |
| Q24537508 | Small interfering RNAs containing full 2'-O-methylribonucleotide-modified sense strands display Argonaute2/eIF2C2-dependent activity |
| Q59137913 | Small non-coding RNA expression in mouse nephrogenic mesenchymal progenitors |
| Q34308999 | Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5' terminal nucleotide |
| Q36974244 | Specialization and evolution of endogenous small RNA pathways |
| Q33998243 | Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome |
| Q35192721 | Specific but interdependent functions for Arabidopsis AGO4 and AGO6 in RNA-directed DNA methylation |
| Q42610466 | Specific residues at every third position of siRNA shape its efficient RNAi activity |
| Q33506607 | Statistical use of argonaute expression and RISC assembly in microRNA target identification |
| Q34590412 | Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release |
| Q36400708 | Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity |
| Q48513428 | Strategies for Improving siRNA-Induced Gene Silencing Efficiency. |
| Q46862317 | Strategies for protein coexpression in Escherichia coli |
| Q41449580 | Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide |
| Q48011755 | Structural Foundations of RNA Silencing by Argonaute |
| Q36574683 | Structural and biochemical advances in mammalian RNAi |
| Q37499514 | Structural and functional modules in RNA interference |
| Q35036960 | Structural basis for microRNA targeting |
| Q36399186 | Structural biology of RNA silencing and its functional implications |
| Q43291103 | Structural determinants of miRNAs for RISC loading and slicer-independent unwinding |
| Q36233604 | Structural domains in RNAi |
| Q27676050 | Structural insights into RISC assembly facilitated by dsRNA-binding domains of human RNA helicase A (DHX9) |
| Q24324404 | Structural insights into RNA processing by the human RISC-loading complex |
| Q50063665 | Structurally modulated codelivery of siRNA and Argonaute 2 for enhanced RNA interference |
| Q27667761 | Structure of C3PO and mechanism of human RISC activation |
| Q27643639 | Structure of the C-terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute-like catalytic triad |
| Q27651827 | Structure of the guide-strand-containing argonaute silencing complex |
| Q27681293 | Structure of yeast Argonaute with guide RNA |
| Q27681119 | Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage |
| Q94024048 | Systematic gene silencing identified Cryptosporidium nucleoside diphosphate kinase and other molecules as targets for suppression of parasite proliferation in human intestinal cells |
| Q36030697 | TAF11 Assembles the RISC Loading Complex to Enhance RNAi Efficiency |
| Q36415326 | Target selectivity in mRNA silencing |
| Q38289525 | TbMP42 is a structure-sensitive ribonuclease that likely follows a metal ion catalysis mechanism |
| Q41655216 | Terminal Duplex Stability and Nucleotide Identity Differentially Control siRNA Loading and Activity in RNA Interference |
| Q34004156 | The 5' terminal uracil of let-7a is critical for the recruitment of mRNA to Argonaute2. |
| Q37096233 | The Argonaute protein family |
| Q36768083 | The Argonautes |
| Q36967620 | The C-terminal motif of SiAGO1b is required for the regulation of growth, development and stress responses in foxtail millet (Setaria italica (L.) P. Beauv) |
| Q36936161 | The Drosophila Dicer-1 Partner Loquacious Enhances miRNA Processing from Hairpins with Unstable Structures at the Dicing Site |
| Q60301190 | The Expanded Universe of Prokaryotic Argonaute Proteins |
| Q27678526 | The Making of a Slicer: Activation of Human Argonaute-1 |
| Q24650156 | The RNA-induced silencing complex: a versatile gene-silencing machine |
| Q29037102 | The RNase H-like superfamily: new members, comparative structural analysis and evolutionary classification |
| Q48182391 | The Slicer Activity of ARGONAUTE1 Is Required Specifically for the Phasing, Not Production, of Trans-Acting Short Interfering RNAs in Arabidopsis. |
| Q27681032 | The Structure of Human Argonaute-2 in Complex with miR-20a |
| Q33753063 | The Tetrahymena argonaute-binding protein Giw1p directs a mature argonaute-siRNA complex to the nucleus. |
| Q37365349 | The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly |
| Q37342304 | The evolution of microRNA pathway protein components in Cnidaria |
| Q35109462 | The initial uridine of primary piRNAs does not create the tenth adenine that Is the hallmark of secondary piRNAs. |
| Q27314922 | The kinase regulator mob1 acts as a patterning protein for stentor morphogenesis |
| Q39591865 | The mechanism of translation initiation on Aichivirus RNA mediated by a novel type of picornavirus IRES. |
| Q37900519 | The miRNA pathway in neurological and skeletal muscle disease: implications for pathogenesis and therapy. |
| Q54228570 | The microRNA Machinery. |
| Q37379332 | The molecular machines that mediate microRNA maturation |
| Q27001268 | The panorama of miRNA-mediated mechanisms in mammalian cells |
| Q34097914 | The role of Dicer protein partners in the processing of microRNA precursors |
| Q24301564 | The role of PACT in the RNA silencing pathway |
| Q30538972 | The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing |
| Q36368745 | The slicing activity of miRNA-specific Argonautes is essential for the miRNA pathway in C. elegans |
| Q39253721 | The stem cell E3-ligase Lin-41 promotes liver cancer progression through inhibition of microRNA-mediated gene silencing |
| Q84530536 | The true core of RNA silencing revealed |
| Q34323847 | Traffic into silence: endomembranes and post-transcriptional RNA silencing |
| Q94450912 | Treatment of breast cancer with autophagy inhibitory microRNAs carried by AGO2-conjugated nanoparticles |
| Q57973165 | Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast |
| Q36575673 | Two molecular features contribute to the Argonaute specificity for the microRNA and RNAi pathways in C. elegans |
| Q36254427 | Uncovering RNAi mechanisms in plants: biochemistry enters the foray |
| Q28083010 | Utility of microRNAs and siRNAs in cervical carcinogenesis |
| Q35110219 | Variables and strategies in development of therapeutic post-transcriptional gene silencing agents |
| Q35172719 | Viral-inducible Argonaute18 confers broad-spectrum virus resistance in rice by sequestering a host microRNA |
| Q57810083 | Virus Sensor RIG-I Represses RNA Interference by Interacting with TRBP through LGP2 in Mammalian Cells |
| Q45417370 | Virus-induced gene silencing of argonaute genes in Nicotiana benthamiana demonstrates that extensive systemic silencing requires Argonaute1-like and Argonaute4-like genes |
| Q55442974 | Why Is a High Temperature Needed by Thermus thermophilus Argonaute During mRNA Silencing: A Theoretical Study. |
| Q34912848 | funRNA: a fungi-centered genomics platform for genes encoding key components of RNAi |
| Q38784668 | miR-34 activity is modulated through 5'-end phosphorylation in response to DNA damage |
| Q36381912 | miR-346 Up-regulates Argonaute 2 (AGO2) Protein Expression to Augment the Activity of Other MicroRNAs (miRNAs) and Contributes to Cervical Cancer Cell Malignancy |
| Q50624742 | miR168 influences phase transition, leaf epinasty, and fruit development via SlAGO1s in tomato. |
| Q28600854 | miRNA Repertoires of Demosponges Stylissa carteri and Xestospongia testudinaria |
| Q31146235 | miRTar2GO: a novel rule-based model learning method for cell line specific microRNA target prediction that integrates Ago2 CLIP-Seq and validated microRNA-target interaction data |
| Q38248221 | microRNA biogenesis, degradation and activity in plants. |
| Q36334930 | microRNA-guided posttranscriptional gene regulation |
| Q46301988 | piRNA Biogenesis in Drosophila melanogaster |
| Q33558210 | siRNA carrying an (E)-vinylphosphonate moiety at the 5΄ end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2. |
| Q36631549 | siRNA efficiency: structure or sequence-that is the question |
| Q35128519 | siRNA repositioning for guide strand selection by human Dicer complexes |
| Q36342076 | siRNA, miRNA and HIV: promises and challenges |
| Q41881864 | siRNA-optimized Modifications for Enhanced In Vivo Activity |
| Q42244084 | siRNAs targeted to certain polyadenylation sites promote specific, RISC-independent degradation of messenger RNAs |
Search more.