RETRACTED: Small molecule-based reversible reprogramming of cellular lifespan

retracted scientific article (publication date: July 2006)

RETRACTED: Small molecule-based reversible reprogramming of cellular lifespan is …
instance of (P31):
scholarly articleQ13442814
retracted paperQ45182324

External links are
P356DOI10.1038/NCHEMBIO800
P698PubMed publication ID16767085
P5875ResearchGate publication ID7016550

P2093author name stringSung Soo Kim
Jaejoon Won
Mina Kim
Tae Kook Kim
Yong-Weon Yi
Jin Hee Ahn
Nuri Kim
Ki-Young Chang
Woo Gil Lee
P2860cites workSenescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.Q53404327
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)Q24293520
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complexQ24295120
Extension of life-span by introduction of telomerase into normal human cellsQ24336088
A biomarker that identifies senescent human cells in culture and in aging skin in vivoQ24562644
Essential and dispensable roles of ATR in cell cycle arrest and genome maintenanceQ24672646
TRF2 Protects Human Telomeres from End-to-End FusionsQ28111898
Polycomb CBX7 has a unifying role in cellular lifespanQ28188425
A magnetic nanoprobe technology for detecting molecular interactions in live cellsQ28259715
Target identification in chemical genetics: the (often) missing linkQ28262958
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cellsQ28288970
Small molecules: the missing link in the central dogmaQ28291345
Cell-cycle checkpoints and cancerQ28293996
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2Q28609749
ATM and related protein kinases: safeguarding genome integrityQ29547735
The phosphatidylinositol 3-Kinase AKT pathway in human cancerQ29547860
Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighborsQ29614306
DNA damage foci at dysfunctional telomeresQ29614811
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATMQ29614843
Protein kinases--the major drug targets of the twenty-first century?Q29615339
A DNA damage checkpoint response in telomere-initiated senescenceQ29615919
ATR and ATM regulate the timing of DNA replication origin firingQ33204272
Chemical genetics: exploring and controlling cellular processes with chemical probesQ33702202
ATM function and telomere stabilityQ34535665
Historical claims and current interpretations of replicative agingQ34713128
Nuclear bodies and compartments: functional roles and cellular signalling in health and diseaseQ35829147
Post-translational modification of p53 in tumorigenesisQ35930703
Exploring biology with small organic moleculesQ35986043
The signals and pathways activating cellular senescenceQ36060167
P5824is retracted byRetraction: small molecule-based reversible reprogramming of cellular lifespanQ28284244
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectlifetimeQ22675021
P304page(s)369-74
P577publication date2006-07-01
P1433published inNature Chemical BiologyQ904026
P1476titleRETRACTED: Small molecule-based reversible reprogramming of cellular lifespan
P478volume2

Reverse relations

cites work (P2860)
Q33685619A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis
Q34531308A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells.
Q92496166APOBEC3B reporter myeloma cell lines identify DNA damage response pathways leading to APOBEC3B expression
Q39706799ATM is the predominant kinase involved in the phosphorylation of histone H2AX after heating
Q96619041Advances in small molecules in cellular reprogramming: effects, structures, and mechanisms
Q40010617Apoptotic death induced by the cyclophosphamide analogue mafosfamide in human lymphoblastoid cells: contribution of DNA replication, transcription inhibition and Chk/p53 signaling
Q28272930Ataxia telangiectasia mutated and p21CIP1 modulate cell survival of drug-induced senescent tumor cells: implications for chemotherapy
Q26852242Ataxia-telangiectasia mutated and the Mre11-Rad50-NBS1 complex: promising targets for radiosensitization
Q39636146Bocavirus Infection Induces a DNA Damage Response That Facilitates Viral DNA Replication and Mediates Cell Death
Q38657645CGK733 does not inhibit ATM or ATR kinase activity in H460 human lung cancer cells.
Q39352434CGK733 enhances multinucleated cell formation and cytotoxicity induced by taxol in Chk1-deficient HBV-positive hepatocellular carcinoma cells
Q38281936Cell context-dependent involvement of ATR in early stages of retroviral replication
Q29615561Cellular senescence: when bad things happen to good cells
Q34042530Characterization of the cellular and antitumor effects of MPI-0479605, a small-molecule inhibitor of the mitotic kinase Mps1.
Q28239738Chemical strategies for development of ATR inhibitors
Q34581035Chronic treatment with resveratrol induces redox stress- and ataxia telangiectasia-mutated (ATM)-dependent senescence in p53-positive cancer cells.
Q39707460Coronavirus infection induces DNA replication stress partly through interaction of its nonstructural protein 13 with the p125 subunit of DNA polymerase δ.
Q81471333Correcting the scientific record
Q37517554DNA structure and integrity checkpoints during the cell cycle and their role in drug targeting and sensitivity of tumor cells to anticancer treatment
Q42007528DNA-PKcs and ATM co-regulate DNA double-strand break repair
Q37270746Design of phenotypic screens for bioactive chemicals and identification of their targets by genetic and proteomic approaches
Q42433750Dissecting the role of p53 phosphorylation in homologous recombination provides new clues for gain-of-function mutants
Q38523589Drugging ATR: progress in the development of specific inhibitors for the treatment of cancer.
Q56681054Editorial Expression of Concern
Q28269485Enhanced DNA-PK-mediated RPA2 hyperphosphorylation in DNA polymerase eta-deficient human cells treated with cisplatin and oxaliplatin
Q53335869Epigenetic control of cellular senescence in disease: opportunities for therapeutic intervention.
Q37824005Frontiers in targeting glioma stem cells
Q38799103H2AX phosphorylation and DNA damage kinase activity are dispensable for herpes simplex virus replication
Q35854679High mobility group box protein-1 promotes cerebral edema after traumatic brain injury via activation of toll-like receptor 4
Q50442670High-content analysis of single cells directly assembled on CMOS sensor based on color imaging.
Q52614753Identification of a checkpoint modulator with synthetic lethality to p53 mutants.
Q35670160Ionizing radiation-induced foci persistence screen to discover enhancers of accelerated senescence
Q35564221Kinase inhibitors with redox and anti-inflammatory activities
Q36978313MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair
Q39275968Manipulation of DNA damage checkpoint signaling in cancer cells by antioxidant biofactor (AOB).
Q39955124Modulation of the DNA-damage response to HZE particles by shielding.
Q37009650Molecular imaging of the ATM kinase activity
Q46744075Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53.
Q35648484Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.
Q46916591Prelamin A accelerates vascular calcification via activation of the DNA damage response and senescence-associated secretory phenotype in vascular smooth muscle cells.
Q28284244Retraction: small molecule-based reversible reprogramming of cellular lifespan
Q37080498Senescence: the good the bad and the dysfunctional
Q33285997Tagged library approach facilitates forward chemical genetics
Q28260348Targeted cancer therapies based on the inhibition of DNA strand break repair
Q35405679Targeting the Ataxia Telangiectasia Mutated Protein in Cancer Therapy
Q37526958Targeting the DNA damage response in cancer
Q36781235Tetraploidization or autophagy: The ultimate fate of senescent human endometrial stem cells under ATM or p53 inhibition
Q39776763The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation
Q41557136The DNA damage response pathway regulates the alternative splicing of the apoptotic mediator Bcl-x
Q35046038The heterogenic final cell cycle of chicken retinal Lim1 horizontal cells is not regulated by the DNA damage response pathway
Q37094171The perinucleolar compartment is directly associated with DNA.
Q30490662Udu deficiency activates DNA damage checkpoint

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