| scholarly article | Q13442814 |
| P50 | author | Sandra Pellegrini | Q56543875 |
| P2093 | author name string | S Davis | |
| G Barbieri | |||
| N Stahl | |||
| O Silvennoinen | |||
| F W Quelle | |||
| N Y Ip | |||
| T G Boulton | |||
| B A Witthuhn | |||
| T Farruggella | |||
| P433 | issue | 5143 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 92-5 | |
| P577 | publication date | 1994-01-07 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components | |
| P478 | volume | 263 |
| Q41098043 | A Kaposi's sarcoma-associated herpesvirus-encoded cytokine homolog (vIL-6) activates signaling through the shared gp130 receptor subunit |
| Q57095483 | A Schwann cell mitogen accompanying regeneration of motor neurons |
| Q33651034 | A Short Receptor Downregulates JAK/STAT Signalling to Control the Drosophila Cellular Immune Response |
| Q38355379 | A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells |
| Q38346752 | A common pro-opiomelanocortin-binding element mediates leukemia inhibitory factor and corticotropin-releasing hormone transcriptional synergy |
| Q24608830 | A critical cytoplasmic domain of the interleukin-5 (IL-5) receptor alpha chain and its function in IL-5-mediated growth signal transduction |
| Q34421126 | A defined, controlled culture system for primary bovine chromaffin progenitors reveals novel biomarkers and modulators |
| Q38360608 | A di-leucine motif and an upstream serine in the interleukin-6 (IL-6) signal transducer gp130 mediate ligand-induced endocytosis and down-regulation of the IL-6 receptor |
| Q52604210 | A fusion protein of the gp130 and interleukin-6Ralpha ligand-binding domains acts as a potent interleukin-6 inhibitor. |
| Q40806236 | A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6. |
| Q24315666 | A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes |
| Q73119707 | A purine-sensitive pathway regulates multiple genes involved in axon regeneration in goldfish retinal ganglion cells |
| Q28609042 | A single STAT recruitment module in a chimeric cytokine receptor complex is sufficient for STAT activation |
| Q34433877 | A single nucleotide polymorphism in Tyk2 controls susceptibility to experimental allergic encephalomyelitis |
| Q52191781 | A sweat gland-derived differentiation activity acts through known cytokine signaling pathways. |
| Q36294699 | A unique loop structure in oncostatin M determines binding affinity toward oncostatin M receptor and leukemia inhibitory factor receptor |
| Q36476001 | ALR and liver regeneration |
| Q33955157 | AM424: history of a novel drug candidate |
| Q36444343 | Actions of neurotrophic factors and their signaling pathways in neuronal survival and axonal regeneration |
| Q41181055 | Activating mechanism of CNTF and related cytokines |
| Q40746454 | Activation and inactivation of signal transducers and activators of transcription by ciliary neurotrophic factor in neuroblastoma cells. |
| Q38301684 | Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes. |
| Q53464396 | Activation of JAK3, but not JAK1, is critical to interleukin-4 (IL4) stimulated proliferation and requires a membrane-proximal region of IL4 receptor alpha. |
| Q38298544 | Activation of acute phase response factor (APRF)/Stat3 transcription factor by growth hormone. |
| Q73274449 | Activation of cellular responses to interleukin 6 is blocked by staurosporine |
| Q35994891 | Activation of the Jak3 pathway and myeloid differentiation |
| Q28212733 | Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways |
| Q28638072 | Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression |
| Q28578042 | Activation of the rat serine proteinase inhibitor 3 gene by interferon gamma via the interleukin 6-responsive element |
| Q41048286 | Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions |
| Q41322816 | Acute phase proteins and transformed cells. |
| Q41673917 | Advances in the understanding of cytokine signal transduction: the role of Jaks and STATs in immunoregulation and the pathogenesis of immunodeficiency |
| Q41157837 | Alanine substitution for Thr268 and Asp269 of soluble ciliary neurotrophic factor (CNTF) receptor alpha component defines a specific antagonist for the CNTF response |
| Q24301863 | An Aminopeptidase, ARTS-1, Is Required for Interleukin-6 Receptor Shedding |
| Q37695667 | An amino acid substitution in the Drosophila hopTum-l Jak kinase causes leukemia-like hematopoietic defects. |
| Q41085793 | An antagonist for the leukemia inhibitory factor receptor inhibits leukemia inhibitory factor, cardiotrophin-1, ciliary neurotrophic factor, and oncostatin M. |
| Q28217100 | An unexpected biochemical and functional interaction between gp130 and the EGF receptor family in breast cancer cells |
| Q27646869 | An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor |
| Q40634557 | Analysis of Stat3 (signal transducer and activator of transcription 3) dimerization by fluorescence resonance energy transfer in living cells |
| Q46803714 | Analysis of leukemia inhibitory factor and leukemia inhibitory factor receptor in embryonic and adult zebrafish (Danio rerio). |
| Q41109670 | Antibodies to rat soluble IL-6 receptor stimulate B9 hybridoma cell proliferation. |
| Q28244618 | Apolipoprotein E binds to and potentiates the biological activity of ciliary neurotrophic factor |
| Q28294908 | Association of the interferon-dependent tyrosine kinase Tyk-2 with the hematopoietic cell phosphatase |
| Q52684420 | BMP-Responsive Protease HtrA1 Is Differentially Expressed in Astrocytes and Regulates Astrocytic Development and Injury Response. |
| Q26866418 | Bacterial and fungal pattern recognition receptors in homologous innate signaling pathways of insects and mammals |
| Q41381573 | Binding characteristics of ciliary neurotrophic factor to sympathetic neurons and neuronal cell lines |
| Q34299734 | Biology of aromatase in the mammary gland |
| Q22306225 | Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis 1 |
| Q34218604 | Blockade of IL-6 Trans signaling attenuates pulmonary fibrosis |
| Q28241734 | Box 3-independent signaling mechanisms are involved in leukemia inhibitory factor receptor alpha- and gp130-mediated stimulation of mitogen-activated protein kinase. Evidence for participation of multiple signaling pathways which converge at Ras |
| Q38296732 | C/EBP-related sites in addition to a STAT site are necessary for ciliary neurotrophic factor-leukemia inhibitory factor-dependent transcriptional activation by the vasoactive intestinal peptide cytokine response element |
| Q24337795 | CNTF mediates neurotrophic factor secretion and fluid absorption in human retinal pigment epithelium |
| Q30360734 | CNTF receptor subunit α as a marker for glioma tumor-initiating cells and tumor grade: laboratory investigation. |
| Q52668580 | CRLF1 promotes malignant phenotypes of papillary thyroid carcinoma by activating the MAPK/ERK and PI3K/AKT pathways. |
| Q24316473 | Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex |
| Q40696536 | Cdk9, a member of the cdc2-like family of kinases, binds to gp130, the receptor of the IL-6 family of cytokines |
| Q62070083 | Cell swelling activates STAT1 and STAT3 proteins in cultured rat hepatocytes |
| Q33638611 | Cellular aspects of trophic actions in the nervous system. |
| Q40932847 | Cellular physiology of STAT3: Where's the cytoplasmic monomer? |
| Q77765383 | Characterization and binding specificity of the monomeric STAT3-SH2 domain |
| Q41293088 | Characterization of active and inactive forms of the JAK2 protein-tyrosine kinase produced via the baculovirus expression vector system |
| Q48259922 | Characterization of receptors for ciliary neurotrophic factor on rat hippocampal astrocytes |
| Q71142692 | Characterization of the receptor binding sites of human leukemia inhibitory factor and creation of antagonists |
| Q28235378 | Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors |
| Q46408371 | Chronic interleukin-6 alters NMDA receptor-mediated membrane responses and enhances neurotoxicity in developing CNS neurons. |
| Q28144767 | Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia |
| Q71410617 | Ciliary neurotrophic factor stimulates the expression of glial fibrillary acidic protein by brain astrocytes in vivo |
| Q42019529 | Ciliary neurotrophic factor, cardiotrophin-like cytokine, and neuropoietin share a conserved binding site on the ciliary neurotrophic factor receptor alpha chain |
| Q41341794 | Ciliary neurotrophic factor-induced gene expression in human neuroblastoma cell lines |
| Q46453197 | Ciliary neurotrophic factor-mediated signaling regulates neuronal versus glial differentiation of retinal stem cells/progenitors by concentration-dependent recruitment of mitogen-activated protein kinase and Janus kinase-signal transducer and activa |
| Q71618719 | Comparative study on the phosphotyrosine motifs of different cytokine receptors involved in STAT5 activation |
| Q35553334 | Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activity |
| Q35763367 | Constitutive activation of different Jak tyrosine kinases in human T cell leukemia virus type 1 (HTLV-1) tax protein or virus-transformed cells |
| Q40981904 | Constitutive internalization and association with adaptor protein-2 of the interleukin-6 signal transducer gp130. |
| Q34270015 | Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice |
| Q34153995 | Contribution of the Box 1 and Box 2 motifs of cytokine receptors to Jak1 association and activation |
| Q40821136 | Coupling of inflammatory cytokine signaling pathways probed by measurements of extracellular acidification rate |
| Q42811240 | Cross-talk among gp130 cytokines in adipocytes |
| Q27681282 | Crystal Structure of Interleukin-6 in Complex with a Modified Nucleic Acid Ligand |
| Q24533188 | Crystal structure of a cytokine-binding region of gp130. |
| Q40416594 | Cytokine receptor signalling |
| Q40667563 | Cytokine suppression of dopamine-beta-hydroxylase by extracellular signal-regulated kinase-dependent and -independent pathways. |
| Q41827765 | Cytokine-induced nuclear factor kappa B activation promotes the survival of developing neurons. |
| Q37895769 | Cytokine-like factor 1 (CLF1): life after development? |
| Q33784715 | Cytokines and STAT signaling |
| Q41188018 | Cytokines in neuronal development |
| Q41597814 | Cytokines which signal through the LIF receptor and their actions in the nervous system |
| Q41881472 | Cytoplasmic STAT proteins associate prior to activation. |
| Q58536169 | Definition of a Composite Binding Site for gp130 in Human Interleukin-6 |
| Q34464999 | Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta |
| Q44425106 | Desensitization of Signaling by Oncostatin M in Human Vascular Cells Involves Cytoplasmic Tyr Residue 759 in gp130 but Is Not Mediated by Either Src Homology 2 Domain-containing Tyrosine Phosphatase 2 or Suppressor of Cytokine Signaling 3 |
| Q38786733 | Developmental Stage-Dependent Effects of Leukemia Inhibitory Factor on Adipocyte Differentiation of Murine Bone Marrow Stromal Cells |
| Q56690299 | Differential Activation of Acute Phase Response Factor/STAT3 and STAT1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130 |
| Q24319880 | Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation |
| Q28637692 | Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation |
| Q28508045 | Differential biological activity of disease-associated JAK2 mutants |
| Q28143778 | Differential regulation of leukemia inhibitory factor-stimulated neuronal gene expression by protein phosphatases SHP-1 and SHP-2 through mitogen-activated protein kinase-dependent and -independent pathways |
| Q38294251 | Differential regulation of the expression of interleukin-2 receptor gamma-chain during the in vitro differentiation of human myeloid cells |
| Q41064397 | Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation |
| Q35824530 | Disruption by interferon-alpha of an autocrine interleukin-6 growth loop in IL-6-dependent U266 myeloma cells by homologous and heterologous down-regulation of the IL-6 receptor alpha- and beta-chains |
| Q34468309 | Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses |
| Q52537943 | Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2-mediated signals in immune responses. |
| Q28245196 | Distinct roles for leukemia inhibitory factor receptor alpha-chain and gp130 in cell type-specific signal transduction |
| Q71400868 | Distinct tumorigenic potential of abl and raf in B cell neoplasia: abl activates the IL-6 signaling pathway |
| Q33526479 | Divergent adaptive and innate immunological responses are observed in humans following blunt trauma. |
| Q28278147 | Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction |
| Q24313382 | Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation |
| Q39446572 | Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells. |
| Q89719229 | Dynamic Changes in pStat3 are Involved in Meiotic Spindle Assembly in Mouse Oocytes |
| Q47780922 | EGFR and KRAS mutations do not enrich for the activation of IL-6, JAK1 or phosphorylated STAT3 in resected lung adenocarcinoma. |
| Q28079973 | Effect of Lead (Pb) on Inflammatory Processes in the Brain |
| Q40435241 | Effects of growth hormone and prolactin immune development and function |
| Q43900122 | Effects of leukemia inhibitory factor on rat skeletal muscles are modulated by clenbuterol |
| Q42464334 | Effects of leukemia inhibitory receptor gene mutations on human hypothalamo-pituitary-adrenal function |
| Q28548490 | Embryonic Stem Cell Growth Factors Regulate eIF2α Phosphorylation |
| Q24656029 | Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor |
| Q33771858 | Erythropoietin and Friend virus gp55 activate different JAK/STAT pathways through the erythropoietin receptor in erythroid cells |
| Q41437901 | Erythropoietin and interleukin-2 activate distinct JAK kinase family members |
| Q33967216 | Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver |
| Q40999358 | Estrogen biosynthesis in adipose. Significance in breast cancer development |
| Q62819858 | Expression of BCR – ABL in M1 myeloid leukemia cells induces differentiation without arresting proliferation |
| Q35641376 | Expression of an activated erythropoietin or a colony-stimulating factor 1 receptor by pluripotent progenitors enhances colony formation but does not induce differentiation |
| Q74576642 | Expression of leukemia inhibitory factor and its receptor in breast cancer: a potential autocrine and paracrine growth regulatory mechanism |
| Q37224637 | Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours |
| Q28298093 | Functional expression of soluble human interleukin-11 (IL-11) receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130 |
| Q38290198 | Functionally active fusion protein of the novel composite cytokine CLC/soluble CNTF receptor |
| Q89550778 | GP130 Cytokines in Breast Cancer and Bone |
| Q39575287 | Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase |
| Q41334493 | Gamma chain-associated cytokine receptors signal through distinct transducing factors |
| Q41711827 | Gene expression, biological effects and clinical aspects of lymphokines |
| Q77903168 | General mechanisms of cytokine receptor signaling |
| Q46444584 | Genetic origins of hyper-IgE syndrome |
| Q34300226 | Genomic structure and promoter characterization of the human Sprouty4 gene, a novel regulator of lung morphogenesis |
| Q38091321 | Glaucoma and optic nerve repair. |
| Q84904908 | Glucocorticoids increase interleukin-6-dependent gene induction by interfering with the expression of the suppressor of cytokine signaling 3 feedback inhibitor |
| Q35632149 | Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways |
| Q41150318 | Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways |
| Q56016875 | Growth Hormone-promoted Tyrosyl Phosphorylation of SHC Proteins and SHC Association with Grb2 |
| Q45888112 | Growth control mechanisms in multiple myeloma |
| Q28590660 | Growth hormone promotes the association of transcription factor STAT5 with the growth hormone receptor |
| Q36566246 | Growth hormone rapidly activates rat serine protease inhibitor 2.1 gene transcription and induces a DNA-binding activity distinct from those of Stat1, -3, and -4. |
| Q42831119 | Growth hormone regulation of SIRP and SHP-2 tyrosyl phosphorylation and association |
| Q72259812 | Growth hormone signaling leading to CYP2C12 gene expression in rat hepatocytes involves phospholipase A2 |
| Q24322608 | Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1 |
| Q57204134 | H2A.Z.1 crosstalk with H3K56-acetylation controls gliogenesis through the transcription of folate receptor |
| Q33737278 | HER2 in Breast Cancer Stemness: A Negative Feedback Loop towards Trastuzumab Resistance |
| Q83832673 | Heparin synergistically enhances interleukin-11 signaling through up-regulation of the MAPK pathway |
| Q35837720 | Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes |
| Q47962791 | Highly conserved amino-acid sequence between murine STAT3 and a revised human STAT3 sequence |
| Q28266613 | Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome |
| Q39019470 | Hyper-IL-6: a potent and efficacious stimulator of RGC regeneration |
| Q38255855 | IL-17RA in intestinal inflammation: structure, signaling, function, and clinical application |
| Q38661146 | IL-6 blockers in systemic onset juvenile idiopathic arthritis |
| Q41134560 | IL-6 cytokine family and signal transduction: a model of the cytokine system |
| Q40700148 | IL-6 mediated activation of STAT3 bypasses Janus kinases in terminally differentiated B lineage cells |
| Q34288655 | IL-6-like cytokines and cancer cachexia: consequences of chronic inflammation |
| Q37768101 | IL-6: regulator of Treg/Th17 balance |
| Q37658504 | IL-9: basic biology, signaling pathways in CD4+ T cells and implications for autoimmunity |
| Q28609579 | Identification and localization of a skeletal muscle secrotonin 5-HT2A receptor coupled to the Jak/STAT pathway |
| Q30840348 | Identification of a gp130 cytokine receptor critical site involved in oncostatin M response. |
| Q38330432 | Identification of a signal transducer and activator of transcription (STAT) binding site in the mouse metallothionein-I promoter involved in interleukin-6-induced gene expression |
| Q34365452 | Identification of amino acid residues of gp130 signal transducer and gp80 alpha receptor subunit that are involved in ligand binding and signaling by human herpesvirus 8-encoded interleukin-6. |
| Q28646364 | Identification of an interferon-gamma receptor alpha chain sequence required for JAK-1 binding |
| Q34784977 | Identification of the interleukin-6/oncostatin M response element in the rat tissue inhibitor of metalloproteinases-1 (TIMP-1) promoter |
| Q36047532 | Impairment of antigen-specific antibody production in transgenic mice expressing a dominant-negative form of gp130. |
| Q35759651 | Inborn errors of anti-viral interferon immunity in humans |
| Q24685955 | Increased expression of the interleukin-11 receptor and evidence of STAT3 activation in prostate carcinoma |
| Q34145804 | Increased levels of soluble interleukin-6 receptor and CCL3 in COPD sputum. |
| Q36371096 | Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation |
| Q40631389 | Induction of an interferon‐γ Stat3 response in nerve cells by pre‐treatment with gp130 cytokines |
| Q41609661 | Induction of low density lipoprotein receptor (LDLR) transcription by oncostatin M is mediated by the extracellular signal-regulated kinase signaling pathway and the repeat 3 element of the LDLR promoter |
| Q46485002 | Induction of neurite outgrowth by interleukin-6 is accompanied by activation of Stat3 signaling pathway in a variant PC12 cell (E2) line |
| Q28569189 | Inflammation induces serine protease inhibitor 3 expression in the rat pineal gland |
| Q54582911 | Influence of interleukin-6 (IL-6) dimerization on formation of the high affinity hexameric IL-6.receptor complex. |
| Q37676036 | Inhibition of IL-6 family cytokines by SOCS3. |
| Q40169151 | Inhibition of IL-6-dependent growth of myeloma cells by an acidic peptide repressing the gp130-mediated activation of Src family kinases |
| Q40685493 | Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells |
| Q55477955 | Inhibition of growth and induction of differentiation of glioma cell lines by oncostatin M (OSM). |
| Q39003208 | Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation. |
| Q36553730 | Inhibition of the Jak-STAT pathway prevents CNTF-mediated survival of axotomized oxytocinergic magnocellular neurons in organotypic cultures of the rat supraoptic nucleus |
| Q41116339 | Integration of Jak-Stat and AP-1 signaling pathways at the vasoactive intestinal peptide cytokine response element regulates ciliary neurotrophic factor-dependent transcription |
| Q39682814 | Interaction between STAT-3 and HNF-3 leads to the activation of liver-specific hepatitis B virus enhancer 1 function |
| Q38153210 | Interaction of Notch and gp130 signaling in the maintenance of neural stem and progenitor cells |
| Q41098851 | Interferon response pathways--a paradigm for cytokine signalling? |
| Q36365369 | Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors |
| Q24306559 | Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12 |
| Q36437560 | Interleukin 12: a potential link between nerve cells and the immune response in inflammatory disorders |
| Q41442971 | Interleukin 2-induced activation of JAK3: possible involvement in signal transduction for c-myc induction and cell proliferation |
| Q41722189 | Interleukin 6 and its receptor: ten years later |
| Q33969763 | Interleukin 6 and liver regeneration |
| Q37553940 | Interleukin 6 and rheumatoid arthritis |
| Q41154380 | Interleukin-13 is a potent activator of JAK3 and STAT6 in cells expressing interleukin-2 receptor-gamma and interleukin-4 receptor-alpha |
| Q42683940 | Interleukin-13 signal transduction in lymphohemopoietic cells. Similarities and differences in signal transduction with interleukin-4 and insulin |
| Q36678242 | Interleukin-3 signals through multiple isoforms of Stat5. |
| Q40806078 | Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs. |
| Q36938072 | Interleukin-6 and its receptor in cancer: implications for translational therapeutics |
| Q34440657 | Interleukin-6 and new strategies for the treatment of cancer, hyperproliferative diseases and paraneoplastic syndromes |
| Q41190907 | Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein |
| Q41210322 | Interleukin-6 in the injured patient. Marker of injury or mediator of inflammation? |
| Q41234442 | Interleukin-6 induces tyrosine phosphorylation of the Ras activating protein Shc, and its complex formation with Grb2 in the human multiple myeloma cell line LP-1. |
| Q34036694 | Interleukin-6 signal transduction and lymphocyte function |
| Q54192931 | Interleukin-6 signaling via four transcription factors binding palindromic enhancers of different genes |
| Q41853993 | Interleukin-6-dependent and -independent regulation of the human C-reactive protein gene |
| Q40764841 | Interleukin-6-induced proliferation of pre-B cells mediated by receptor complexes lacking the SHP2/SOCS3 recruitment sites revisited. |
| Q38298501 | Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction |
| Q38305606 | Interleukin-6-induced tethering of STAT3 to the LAP/C/EBPbeta promoter suggests a new mechanism of transcriptional regulation by STAT3. |
| Q24531184 | Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway |
| Q38288110 | Interleukin-6: a new therapeutic target in systemic sclerosis? |
| Q88562718 | Interleukin-6: designing specific therapeutics for a complex cytokine |
| Q36280356 | Interleukin-6: structure-function relationships. |
| Q42674535 | Interleukin‐7 induces the association of phosphatidylinositol 3‐kinase with the α chain of the interleukin‐7 receptor |
| Q41905277 | Internalization of the interleukin 6 signal transducer gp130 does not require activation of the Jak/STAT pathway |
| Q93020284 | Intragenic regulation of SOCS3 isoforms |
| Q41121963 | Involvement of Stat3 in interleukin-6-induced IgM production in a human B-cell line |
| Q78111677 | Involvement of gp130-mediated signaling in pressure overload-induced activation of the JAK/STAT pathway in rodent heart |
| Q44801081 | Involvement of reactive oxygen species in cardiotrophin-1-induced proliferation of cardiomyocytes differentiated from murine embryonic stem cells |
| Q28244421 | Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells |
| Q73674442 | Involving of the cytoplasmic region of leukemia inhibitory factor receptor alpha subunit, IL-6 related signal transducer-gp130 or fas death domain for MAPK p42/44 activation in HL-60 cell with LIF or anti-Fas IgG |
| Q41111395 | Isolation and characterization of a leukemia inhibitory factor-independent embryonic stem cell line. |
| Q50292718 | JAK activation |
| Q90591179 | JAK-STAT pathway targeting for the treatment of inflammatory bowel disease |
| Q28507456 | JAK/STAT signaling pathway mediates cytokine-induced iNOS expression in primary astroglial cell cultures |
| Q41138516 | JAK1/2 inhibition impairs T cell function in vitro and in patients with myeloproliferative neoplasms |
| Q24612039 | JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region |
| Q50292700 | JAKs bind LIFR |
| Q50292706 | JAKs bind OSMR |
| Q24316448 | Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis |
| Q28270987 | Jak2 is essential for signaling through a variety of cytokine receptors |
| Q40506662 | Jaks and Stats in signaling by the cytokine receptor superfamily |
| Q39896286 | Janus kinase inhibitor INCB20 has antiproliferative and apoptotic effects on human myeloma cells in vitro and in vivo |
| Q28609580 | Janus kinase-dependent activation of insulin receptor substrate 1 in response to interleukin-4, oncostatin M, and the interferons |
| Q24806655 | Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation |
| Q34103659 | Janus kinases: components of multiple signaling pathways |
| Q92224146 | Joint Location-Specific JAK-STAT Signaling in Rheumatoid Arthritis Fibroblast-like Synoviocytes |
| Q38318315 | KSHV-encoded viral IL-6 activates multiple human IL-6 signaling pathways |
| Q34644229 | Kaposi Sarcoma Pathogenesis: A Triad of Viral Infection, Oncogenesis and Chronic Inflammation. |
| Q77676407 | LIF (AM424), a promising growth factor for the treatment of ALS |
| Q35161466 | LIF upregulates expression of NK-1R in NHBE cells |
| Q41506945 | LIFR functions as a metastasis suppressor in hepatocellular carcinoma by negatively regulating phosphoinositide 3-kinase/AKT pathway |
| Q35274375 | Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model |
| Q48191476 | Leukaemia inhibitory factor prevents loss of p75-nerve growth factor receptor immunoreactivity in medial septal neurons following fimbria-fornix lesions |
| Q37262606 | Leukemia Inhibitory Factor Protects Neurons from Ischemic Damage via Upregulation of Superoxide Dismutase 3. |
| Q34308344 | Leukemia inhibitor factor promotes functional recovery and oligodendrocyte survival in rat models of focal ischemia |
| Q28082576 | Leukemia inhibitory factor (LIF) |
| Q37354208 | Leukemia inhibitory factor (LIF) stimulates proopiomelanocortin (POMC) expression in a corticotroph cell line. Role of STAT pathway |
| Q62819502 | Leukemia inhibitory factor and its receptor |
| Q35070591 | Leukemia inhibitory factor downregulates human papillomavirus-16 oncogene expression and inhibits the proliferation of cervical carcinoma cells. |
| Q36010728 | Leukemia inhibitory factor inhibits HIV-1 replication and is upregulated in placentae from nontransmitting women |
| Q33642687 | Leukemia inhibitory factor regulates trophoblast giant cell differentiation via Janus kinase 1-signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway. |
| Q33603565 | Leukemia inhibitory factor secretion is a predictor and indicator of early progenitor status in adult bone marrow stromal cells |
| Q90714236 | Leukemia inhibitory factor signaling in Xenopus embryo: Insights from gain of function analysis and dominant negative mutant of the receptor |
| Q24564233 | Leukemia inhibitory factor, a cytokine at the interface between neurobiology and immunology |
| Q36254804 | Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells |
| Q37981265 | Leukemia inhibitory factor: a paracrine mediator of bone metabolism. |
| Q41306651 | Ligand-dependent and -independent activation of the transcription factor gamma RF-1 in a cell-free system |
| Q40019119 | Ligand-induced assembly and activation of the gamma interferon receptor in intact cells |
| Q28588237 | Localization of gp130 in the developing and adult mouse cerebellum |
| Q44524128 | Long term association of the cytokine receptor gp130 and the Janus kinase Jak1 revealed by FRAP analysis |
| Q40401298 | Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contributions of Src- and receptor-tyrosine kinases |
| Q41208928 | Mechanisms of inhibition of IL-6-mediated immunoglobulin secretion by dexamethasone and suramin in human lymphoid and myeloma cell lines |
| Q41349290 | Mediation of growth hormone-dependent transcriptional activation by mammary gland factor/Stat 5. |
| Q30997978 | Members of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway are present and active in human sperm |
| Q64067711 | Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade |
| Q24313379 | Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth |
| Q42800581 | Microinjected cDNA encoding JAK2 protein-tyrosine kinase induces DNA synthesis in NIH 3T3 cells |
| Q46893501 | Minimal role for STAT1 in interleukin-6 signaling and actions in the murine brain |
| Q26750616 | Mitochondrial Stat3, the Need for Design Thinking |
| Q39328853 | Model-driven experimental analysis of the function of SHP-2 in IL-6-induced Jak/STAT signaling. |
| Q71980365 | Modulation of human hepatocyte acute phase protein production in vitro by n-3 and n-6 polyunsaturated fatty acids |
| Q44804711 | Molecular analysis of signaling events mediated by the cytoplasmic domain of leukemia inhibitory factor receptor alpha subunit |
| Q44485443 | Molecular and cellular alterations induced by sustained expression of ciliary neurotrophic factor in a mouse model of retinitis pigmentosa |
| Q34098586 | Molecular aspects of multiple myeloma. |
| Q28609565 | Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transduction |
| Q24305237 | Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway |
| Q36745947 | Molecular cloning of rat JAK3, a novel member of the JAK family of protein tyrosine kinases |
| Q46217235 | Molecular cloning of tyrosine kinases in the early Xenopus embryo: identification of Eck-related genes expressed in cranial neural crest cells of the second (hyoid) arch |
| Q73692223 | Molecular modeling-guided mutagenesis of the extracellular part of gp130 leads to the identification of contact sites in the interleukin-6 (IL-6).IL-6 receptor.gp130 complex |
| Q41670812 | Multiple myeloma: increasing evidence for a multistep transformation process |
| Q48455897 | Multiple routes to astrocytic differentiation in the CNS. |
| Q30404730 | Neuronal Survival, Morphology and Outgrowth of Spiral Ganglion Neurons Using a Defined Growth Factor Combination |
| Q46444365 | Neuroprotective effects of cardiotrophin-like cytokine on retinal ganglion cells |
| Q36983344 | Neurotrophic factor control of satiety and body weight |
| Q33582060 | Neurotrophic factors and neurologic disease |
| Q40418112 | Neurotrophic factors and their receptors |
| Q22010578 | Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family |
| Q24313489 | Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins |
| Q61812442 | Obesity-Induced TNFα and IL-6 Signaling: The Missing Link between Obesity and Inflammation-Driven Liver and Colorectal Cancers |
| Q42914271 | Oncostatin M decreases interleukin-1 β secretion by human synovial fibroblasts and attenuates an acute inflammatory reaction in vivo. |
| Q24678591 | Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells |
| Q40794984 | Oncostatin M-induced growth inhibition and morphological changes of MDA-MB231 breast cancer cells are abolished by blocking the MEK/ERK signaling pathway. |
| Q50642120 | Oocytes. |
| Q38355174 | Other kinases can substitute for Jak2 in signal transduction by interferon-gamma |
| Q61763092 | PDGF stimulates tyrosine phosphorylation of JAK 1 protein tyrosine kinase in human mesangial cells |
| Q33924660 | Partial impairment of cytokine responses in Tyk2-deficient mice |
| Q41217245 | Participation of JAK and STAT proteins in growth hormone-induced signaling |
| Q36243982 | Pathological role of IL-6 in the experimental allergic bronchial asthma in mice |
| Q34329668 | Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2. |
| Q28637388 | Phosphorylation and internalization of gp130 occur after IL-6 activation of Jak2 kinase in hepatocytes |
| Q42801932 | Phosphorylation of human gp130 at Ser-782 adjacent to the Di-leucine internalization motif. Effects on expression and signaling |
| Q24563149 | Phosphorylation of the human leukemia inhibitory factor (LIF) receptor by mitogen-activated protein kinase and the regulation of LIF receptor function by heterologous receptor activation |
| Q39742952 | Phosphorylation states of STAT3 and ERKs in mouse embryonic stem cells |
| Q35625634 | Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor beta and gamma chains. |
| Q40642451 | Physiological and pathological roles of interleukin-6 in the central nervous system |
| Q28645718 | Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins |
| Q54590336 | Potentiation of transmitter release by ciliary neurotrophic factor requires somatic signaling. |
| Q42816294 | Preassociation of STAT1 with STAT2 and STAT3 in separate signalling complexes prior to cytokine stimulation |
| Q31104620 | Precise mapping of the CD95 pre-ligand assembly domain |
| Q37195035 | Preconditioning-induced protection from oxidative injury is mediated by leukemia inhibitory factor receptor (LIFR) and its ligands in the retina |
| Q24530173 | Principles of interleukin (IL)-6-type cytokine signalling and its regulation |
| Q74086543 | Production of growth related oncogene protein-alpha in human umbilical vein endothelial cells stimulated with soluble interleukin-6 receptor-alpha: role of signal transducers, janus kinase 2 and mitogen-activated kinase kinase |
| Q49215677 | Profile of tocilizumab and its potential in the treatment of giant cell arteritis. |
| Q33858319 | Proinflammatory stem cell signaling in cardiac ischemia |
| Q35620265 | Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation |
| Q36712274 | Prolactin induces growth inhibition and promotes differentiation of CHO cells stably transfected with prolactin receptor complementary DNA. |
| Q40793223 | Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription |
| Q34024246 | Proliferation of immature myeloma cells by interleukin-6 is associated with CD45 expression in human multiple myeloma |
| Q26862803 | Promoting myelin repair and return of function in multiple sclerosis |
| Q28303512 | Protein kinase A (PKA)- and protein kinase C-phosphorylated glia maturation factor promotes the catalytic activity of PKA |
| Q44166573 | Protein kinase C delta associates with the interleukin-6 receptor subunit glycoprotein (gp) 130 via Stat3 and enhances Stat3-gp130 interaction |
| Q28571171 | Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells |
| Q41639708 | Protein tyrosine phosphorylation: implications for synaptic function |
| Q44013866 | RETRACTED: Interleukin-6 receptor expression in contracting human skeletal muscle: regulating role of IL-6. |
| Q40794182 | Rational design of a receptor super-antagonist of human interleukin-6. |
| Q28288032 | Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor |
| Q48227541 | Regulation of nociceptin/orphanin FQ gene expression by neuropoietic cytokines and neurotrophic factors in neurons and astrocytes |
| Q72036821 | Requirement of tyrosine residues 333 and 338 of the growth hormone (GH) receptor for selected GH-stimulated function |
| Q64052490 | Response to IL-6 trans- and IL-6 classic signalling is determined by the ratio of the IL-6 receptor α to gp130 expression: fusing experimental insights and dynamic modelling |
| Q57374260 | Retrograde activation of STAT3 by leukemia inhibitory factor in sympathetic neurons |
| Q34023371 | Role of Tyk-2 in Th9 and Th17 cells in allergic asthma |
| Q35800446 | Role of interferon alpha/beta receptor chain 1 in the structure and transmembrane signaling of the interferon alpha/beta receptor complex. |
| Q35066719 | Role of the JAK/STAT signal transduction pathway in the regulation of gene expression in CNS. |
| Q41143249 | Role of tyrosine kinases in lymphocyte activation: targets for drug intervention |
| Q92528596 | Roles of JAK2 in Aging, Inflammation, Hematopoiesis and Malignant Transformation |
| Q38287574 | Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor |
| Q33941380 | Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors |
| Q41252634 | Roles of gp130 signaling pathways in cardiac myocytes: recent advances and implications for cardiovascular disease |
| Q28211408 | SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130 |
| Q46931098 | SHP2-mediated signaling cascade through gp130 is essential for LIF-dependent I CaL, [Ca2+]i transient, and APD increase in cardiomyocytes |
| Q34768271 | STAT protein complexes activated by interferon-gamma and gp130 signaling molecules differ in their sequence preferences and transcriptional induction properties |
| Q52196597 | STAT signaling is active during early mammalian development. |
| Q34087183 | STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase |
| Q28589273 | STAT3 down-regulates the expression of cyclin D during liver development |
| Q40908937 | STAT3 mediates IL-6-induced growth inhibition in the human prostate cancer cell line LNCaP. |
| Q40905638 | STAT3 mediates IL-6-induced neuroendocrine differentiation in prostate cancer cells . |
| Q40993836 | STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition |
| Q24644334 | STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation |
| Q36481079 | STAT3: a potential therapeutic target in dendritic cells for the induction of transplant tolerance |
| Q41488328 | Secretion of interleukin-6 by bone marrow mesenchymal stem cells promotes metastasis in hepatocellular carcinoma |
| Q24600230 | Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3 |
| Q38301190 | Sequential activation of Rac-1, SEK-1/MKK-4, and protein kinase Cdelta is required for interleukin-6-induced STAT3 Ser-727 phosphorylation and transactivation |
| Q40375770 | Signal transduction and activation of gene transcription by interferons. |
| Q36795284 | Signal transduction pathways that contribute to myeloid differentiation |
| Q47992455 | Signaling mechanisms through gp130: a model of the cytokine system |
| Q41127014 | Signaling of the cardiotrophin-1 receptor. Evidence for a third receptor component. |
| Q28241135 | Signaling of type II oncostatin M receptor |
| Q34084585 | Signaling pathway of ciliary neurotrophic factor in neuroblastoma cell lines |
| Q28211346 | Signaling pathways recruited by the cardiotrophin-like cytokine/cytokine-like factor-1 composite cytokine: specific requirement of the membrane-bound form of ciliary neurotrophic factor receptor alpha component |
| Q34012843 | Signaling through a novel domain of gp130 mediates cell proliferation and activation of Hck and Erk kinases |
| Q34067425 | Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1. |
| Q45057942 | Stat3 signaling is present and active during development of the central nervous system and eye of vertebrates |
| Q42002783 | Stat3 signaling regulates embryonic stem cell fate in a dose-dependent manner |
| Q28243701 | Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation |
| Q41369679 | Structural domains of interleukin-2 receptor beta critical for signal transduction: kinase association and nuclear complex-formation |
| Q24533565 | Structural requirements of the interleukin-6 signal transducer gp130 for its interaction with Janus kinase 1: the receptor is crucial for kinase activation |
| Q28584775 | Structure and function of a new STAT-induced STAT inhibitor |
| Q38315557 | Studies on the interleukin-6-type cytokine signal transducer gp130 reveal a novel mechanism of receptor activation by monoclonal antibodies |
| Q53061725 | Study on the activity of the signaling pathways regulating hepatocytes from G0 phase into G1 phase during rat liver regeneration. |
| Q46545637 | Synergistic induction of neurite outgrowth by nerve growth factor or epidermal growth factor and interleukin-6 in PC12 cells |
| Q42823398 | Syp associates with gp130 and Janus kinase 2 in response to interleukin-11 in 3T3-L1 mouse preadipocytes |
| Q47692804 | T-cell interleukin-6 receptor binding in patients with myasthenia gravis |
| Q46186932 | TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity |
| Q28272795 | Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders |
| Q39065047 | Targeting antioxidant enzyme expression as a therapeutic strategy for ischemic stroke. |
| Q34782075 | Targeting oligodendrocyte protection and remyelination in multiple sclerosis |
| Q48559607 | Teaching resources. Cytokine receptors and Jak-STAT signaling |
| Q40893109 | Termination of IL-6-induced STAT activation is independent of receptor internalization but requires de novo protein synthesis. |
| Q51766789 | The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects. |
| Q28282449 | The Hyper-IgE Syndromes: Lessons in Nature, From Bench to Bedside |
| Q39274304 | The Janus Kinase (JAK) FERM and SH2 Domains: Bringing Specificity to JAK-Receptor Interactions |
| Q28505904 | The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities |
| Q40778041 | The Stat1 binding motif of the interferon-gamma receptor is sufficient to mediate Stat5 activation and its repression by SOCS3. |
| Q38299420 | The YXXQ motif in gp 130 is crucial for STAT3 phosphorylation at Ser727 through an H7-sensitive kinase pathway |
| Q41350973 | The action of interleukin-2 receptor subunits defines a new type of signaling mechanism for hematopoietin receptors in hepatic cells and fibroblasts |
| Q36242620 | The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals |
| Q40988652 | The box-1 region of the leukemia inhibitory factor receptor alpha-chain cytoplasmic domain is sufficient for hemopoietic cell proliferation and differentiation. |
| Q34427696 | The cellular and molecular basis of peripheral nerve regeneration |
| Q24291080 | The ciliary neurotrophic factor receptor alpha component induces the secretion of and is required for functional responses to cardiotrophin-like cytokine |
| Q24290231 | The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6 |
| Q28565647 | The complex of ciliary neurotrophic factor-ciliary neurotrophic factor receptor alpha up-regulates connexin43 and intercellular coupling in astrocytes via the Janus tyrosine kinase/signal transducer and activator of transcription pathway |
| Q28236785 | The conserved box 1 motif of cytokine receptors is required for association with JAK kinases |
| Q40810927 | The designer cytokine hyper-IL-6 mediates growth inhibition and GM-CSF-dependent rejection of B16 melanoma cells |
| Q22010585 | The growth hormone receptor associates with Jak1, Jak2 and Tyk2 in human liver |
| Q38308529 | The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family |
| Q52361158 | The length of the interleukin-11 receptor stalk determines its capacity for classic signaling. |
| Q81066800 | The logic of signaling from the cell surface to the nucleus |
| Q41313217 | The membrane proximal region of the cytoplasmic domain of the growth hormone receptor is involved in the activation of Stat 3. |
| Q91864877 | The molecular details of cytokine signaling via the JAK/STAT pathway |
| Q33720578 | The oncostatin M signalling pathway: reversing the neoplastic phenotype? |
| Q99593488 | The palmitoyl acyltransferases ZDHHC5 and ZDHHC8 are uniquely present in DRG axons and control retrograde signaling via the Gp130/JAK/STAT3 pathway |
| Q28637904 | The protein tyrosine phosphatase SHP-2 negatively regulates ciliary neurotrophic factor induction of gene expression |
| Q37099883 | The role of IL-27 in the induction of anti-tumor cytotoxic T lymphocyte response |
| Q28577475 | The role of Stat and C/EBP transcription factors in the synergistic activation of rat serine protease inhibitor-3 gene by interleukin-6 and dexamethasone |
| Q42607396 | The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis: critical determinants of disease susceptibility and progression? |
| Q36979956 | The role of interleukin-6 in insulin resistance, body fat distribution and energy balance |
| Q34204071 | The role of interleukin-6 in the human adrenal gland. |
| Q35180002 | The role of the JAK-STAT pathway in neural stem cells, neural progenitor cells and reactive astrocytes after spinal cord injury |
| Q40617733 | The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling |
| Q35127430 | The role of the interleukin‐6 family of cytokines in inflammatory arthritis and bone turnover |
| Q48145743 | The role of the leukemia inhibitory factor receptor in neuroprotective signaling |
| Q41387021 | The signal transducer gp130 is shared by interleukin-6 family of haematopoietic and neurotrophic cytokines |
| Q41929935 | The thrombopoietin receptor can mediate proliferation without activation of the Jak-STAT pathway |
| Q34996767 | The two faces of IL-6 on Th1/Th2 differentiation |
| Q40970057 | Thrombopoietin-induced conformational change in p53 lies downstream of the p44/p42 mitogen activated protein kinase cascade in the human growth factor-dependent cell line M07e |
| Q38110210 | Tocilizumab in pediatric rheumatology: the clinical experience |
| Q38303140 | Transforming growth factor-beta and ciliary neurotrophic factor synergistically induce vasoactive intestinal peptide gene expression through the cooperation of Smad, STAT, and AP-1 sites |
| Q37235217 | Trisomy 21 consistently activates the interferon response. |
| Q47674900 | TrkB signalling inhibits p75-mediated apoptosis induced by nerve growth factor in embryonic proprioceptive neurons |
| Q40806570 | Two distinct and independent sites on IL-6 trigger gp 130 dimer formation and signalling |
| Q41379462 | Two distinct signalling pathways are involved in the control of the biphasic junB transcription induced by interleukin-6 in the B cell hybridoma 7TD1. |
| Q41153893 | Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis. |
| Q33924665 | Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function |
| Q33750852 | Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27 |
| Q40966699 | Tyrosines 905 and 915 of gp130 are required for maximum induction of m2 muscarinic acetylcholine receptor and VIP gene transcription by cytokines in neuronal cells |
| Q36895354 | Ubiquitin-mediated regulation of JAK-STAT signaling in embryonic stem cells |
| Q35550033 | Viral interleukin-6: role in Kaposi's sarcoma-associated herpesvirus: associated malignancies |
| Q34378756 | gp130 at the nexus of inflammation, autoimmunity, and cancer |
| Q41198145 | gp130 transducing receptor cross-linking is sufficient to induce interleukin-6 type responses |
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