Transcriptional gene silencing through epigenetic changes mediated by non-coding RNAs

scientific article

Transcriptional gene silencing through epigenetic changes mediated by non-coding RNAs is …
instance of (P31):
scholarly articleQ13442814

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P3181OpenCitations bibliographic resource ID4909741
P932PMC publication ID2861437
P698PubMed publication ID20373265

P50authorBarbora MalecovaQ42769176
P2093author name stringKevin V Morris
P2860cites workTranscriptional silencing of nonsense codon-containing immunoglobulin minigenesQ46468061
Inhibiting transcription of chromosomal DNA with antigene peptide nucleic acids.Q46891008
Non-coding RNAs in polycomb/trithorax regulationQ51778022
Crucial role of antisense transcription across the Xist promoter in Tsix-mediated Xist chromatin modificationQ51970592
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectQ21061203
The genetic signatures of noncoding RNAsQ21092463
The Polycomb group protein EZH2 directly controls DNA methylationQ24299020
RNA exosome depletion reveals transcription upstream of active human promotersQ24321777
An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cellsQ24530726
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcriptionQ24534441
Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genesQ24546155
Novel RNAs identified from an in-depth analysis of the transcriptome of human chromosomes 21 and 22Q24594479
RNA and transcriptional modulation of gene expressionQ24605231
A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndromeQ24644175
EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotencyQ24645960
MicroRNA-373 induces expression of genes with complementary promoter sequencesQ24652547
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNAQ24655224
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAsQ24673619
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesisQ24673923
Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replicationQ24675218
Small dsRNAs induce transcriptional activation in human cellsQ24676787
The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferaseQ24678267
Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste proteinQ24682617
The transcriptional landscape of the mammalian genomeQ27861110
Long non-coding RNAs: insights into functionsQ28131764
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammalsQ28131802
Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylationQ28139187
DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promotersQ28140428
DNA methyltransferase Dnmt1 associates with histone deacetylase activityQ28141500
Transcriptional maps of 10 human chromosomes at 5-nucleotide resolutionQ28241731
The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1Q28252004
Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cellsQ28260424
Involvement of AGO1 and AGO2 in mammalian transcriptional silencingQ28260436
Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAsQ28291487
Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promotersQ28302903
Small RNAs in transcriptional gene silencing and genome defenceQ28307317
The non-coding Air RNA is required for silencing autosomal imprinted genesQ28504980
The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatinQ28506981
G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcriptionQ28513698
Genome-wide and locus-specific DNA hypomethylation in G9a deficient mouse embryonic stem cellsQ28585438
Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1Q28589840
Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9Q28594945
Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3Q28609869
Epigenetic changes in cancerQ37016201
Polycomb complexes and epigenetic statesQ37148660
Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cellsQ37234973
Prolonged transcriptional silencing and CpG methylation induced by siRNAs targeted to the HIV-1 promoter regionQ37331647
Common themes in siRNA-mediated epigenetic silencing pathways.Q37468771
Mechanisms of transcriptional repression by histone lysine methylationQ37468805
The plasticity of the mammalian transcriptomeQ37589131
Emerging similarities in epigenetic gene silencing by long noncoding RNAsQ37591357
SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cellsQ37719468
Mobilization-competent Lentiviral Vector-mediated Sustained Transcriptional Modulation of HIV-1 ExpressionQ39503586
SATB1 reprogrammes gene expression to promote breast tumour growth and metastasisQ40002893
Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitroQ40019565
A transient heterochromatic state in Xist preempts X inactivation choice without RNA stabilizationQ40310454
Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylationQ40396552
The imprinted Air ncRNA is an atypical RNAPII transcript that evades splicing and escapes nuclear exportQ41829208
The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cellsQ43207523
Biochemical fractionation reveals association of DNA methyltransferase (Dnmt) 3b with Dnmt1 and that of Dnmt 3a with a histone H3 methyltransferase and Hdac1.Q44343231
Short hairpin RNA-directed cytosine (CpG) methylation of the RASSF1A gene promoter in HeLa cellsQ45345566
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosomeQ29547359
Antisense transcription in the mammalian transcriptomeQ29547536
Evolution and functions of long noncoding RNAsQ29614331
Divergent transcription from active promotersQ29614332
Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulationQ29614333
RNA maps reveal new RNA classes and a possible function for pervasive transcriptionQ29614334
Global identification of human transcribed sequences with genome tiling arraysQ29614335
The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleusQ29614336
Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteinsQ29614507
Partitioning and plasticity of repressive histone methylation states in mammalian chromatinQ29614513
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sitesQ29615395
New nomenclature for chromatin-modifying enzymesQ29616425
The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleusQ29617834
Widespread occurrence of antisense transcription in the human genomeQ29618539
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locusQ29619815
Role of histone methyltransferase G9a in CpG methylation of the Prader-Willi syndrome imprinting centerQ30310519
Bidirectional transcription directs both transcriptional gene activation and suppression in human cellsQ33384427
Tsix, a gene antisense to Xist at the X-inactivation centreQ33857857
Xist gene regulation at the onset of X inactivationQ34016932
Regulation of endothelial nitric oxide synthase by small RNA.Q34144532
Small interfering RNA-induced transcriptional gene silencing in human cellsQ34161327
Stem cells and cancer; the polycomb connectionQ34341685
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis.Q34485045
Activating gene expression in mammalian cells with promoter-targeted duplex RNAsQ34607180
Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF.Q34619960
Promoter-associated RNA is required for RNA-directed transcriptional gene silencing in human cellsQ34653770
X chromosome dosage compensation: how mammals keep the balanceQ34657007
The antisense transcriptomes of human cellsQ34895481
Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cellsQ34966942
Long antisense non-coding RNAs function to direct epigenetic complexes that regulate transcription in human cellsQ34994197
Hematopoietic precursor cells transiently reestablish permissiveness for X inactivationQ35071298
Two distinct mechanisms of silencing by the KvDMR1 imprinting control regionQ36392021
Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.Q36572080
Studies on the mechanism of RNAi-dependent heterochromatin assemblyQ36768183
Ezh1 and Ezh2 maintain repressive chromatin through different mechanismsQ36810306
Closed chromatin architecture is induced by an RNA duplex targeting the HIV-1 promoter regionQ36838738
MicroRNA-directed transcriptional gene silencing in mammalian cellsQ36945167
Antisense transcripts are targets for activating small RNAsQ36952980
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectgene silencingQ1431332
P304page(s)214-222
P577publication date2010-04-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inCurrent Opinion in Molecular TherapeuticsQ15750358
P1476titleTranscriptional gene silencing through epigenetic changes mediated by non-coding RNAs
P478volume12

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cites work (P2860)
Q347236517SK small nuclear RNA directly affects HMGA1 function in transcription regulation
Q36948870A Potential Suppressive Effect of Natural Antisense IL-1β RNA on Lipopolysaccharide-Induced IL-1β Expression
Q34329463A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells
Q36212913AS1DHRS4, a head-to-head natural antisense transcript, silences the DHRS4 gene cluster in cis and trans
Q90199025An MXD1-derived repressor peptide identifies noncoding mediators of MYC-driven cell proliferation
Q89623329Argonaute Proteins: From Structure to Function in Development and Pathological Cell Fate Determination
Q37802011At the stem of youth and health
Q38614582CRISPR/Cas9: molecular tool for gene therapy to target genome and epigenome in the treatment of lung cancer
Q28660423Characterization of human pseudogene-derived non-coding RNAs for functional potential
Q42171978Chemically Modified Oligonucleotides Modulate an Epigenetically Varied and Transient Form of Transcription Silencing of HIV-1 in Human Cells
Q27691396Chromatin structure of pluripotent stem cells and induced pluripotent stem cells.
Q26781275Controlling HIV-1: Non-Coding RNA Gene Therapy Approaches to a Functional Cure
Q34475613Deciphering Squamous Cell Carcinoma Using Multidimensional Genomic Approaches
Q37844791Developmental control of imprinted expression by macro non-coding RNAs
Q35154309Diabetic embryopathy: a role for the epigenome?
Q35914852Effects of sequence variation on differential allelic transcription factor occupancy and gene expression
Q34438221Elements between the IgH variable (V) and diversity (D) clusters influence antisense transcription and lineage-specific V(D)J recombination
Q42907465Enhanced cisplatin cytotoxicity by RNA interfering the excision repair cross-complementing gene 1 in lung cancer cell A549/DDP
Q33629880Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148
Q58800504Generation of HIV-Resistant Macrophages from IPSCs by Using Transcriptional Gene Silencing and Promoter-Targeted RNA
Q37689132Genetic and Epigenomic Footprints of Folate
Q38974979High expression of CAI2, a 9p21-embedded long noncoding RNA, contributes to advanced-stage neuroblastoma
Q37988197MicroRNAs and Hematopoietic Cell Development
Q37591541Noisy silence: non-coding RNA and heterochromatin formation at repetitive elements
Q90382816Non-coding RNA in C9orf72-related amyotrophic lateral sclerosis and frontotemporal dementia: A perfect storm of dysfunction
Q34185471Perspectives on the Discovery of Small-Molecule Modulators for Epigenetic Processes
Q36553617Pivots of pluripotency: the roles of non-coding RNA in regulating embryonic and induced pluripotent stem cells
Q35133922Promoter Targeting RNAs: Unexpected Contributors to the Control of HIV-1 Transcription
Q37489352Promoter Targeting shRNA Suppresses HIV-1 Infection In vivo Through Transcriptional Gene Silencing
Q34028020RITS—connecting transcription, RNA interference, and heterochromatin assembly in fission yeast
Q37965791RNA and epigenetic silencing: Insight from fission yeast
Q47287262RNA templating of molecular assembly and covalent modification patterning in early molecular evolution and modern biosystems
Q35036850Sequence and expression characteristics of long noncoding RNAs in honey bee caste development--potential novel regulators for transgressive ovary size
Q34315920Snapshots: chromatin control of viral infection
Q35089611The emerging role of RNA in the regulation of gene transcription in human cells
Q34374266The expression of tubulin cofactor A (TBCA) is regulated by a noncoding antisense Tbca RNA during testis maturation.
Q26852914The functions of natural antisense transcripts
Q35969352The genetic and epigenetic journey of embryonic stem cells into mature neural cells.
Q35055739The redox basis of epigenetic modifications: from mechanisms to functional consequences.
Q38365167The relationship between transcription initiation RNAs and CCCTC-binding factor (CTCF) localization
Q36612608The role of microRNAs in hematopoietic stem cell and leukemic stem cell function
Q34457836The theory of RNA-mediated gene evolution
Q34521385Transcriptional gene silencing in humans
Q35667591Transcriptional gene silencing of HIV-1 through promoter targeted RNA is highly specific
Q45316876Transcriptional regulation by small RNAs
Q90627177Transcriptomic profiles of muscle, heart, and spleen in reaction to circadian heat stress in Ethiopian highland and lowland male chicken

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