review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Guido Kroemer | Q19508945 |
Pierre Fenaux | Q30170095 | ||
P2093 | author name string | T Braun | |
G Carvalho | |||
C Fabre | |||
J Grosjean | |||
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Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO | Q24303248 | ||
Structure and functions of the 20S and 26S proteasomes | Q24328777 | ||
The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma | Q27824784 | ||
The c-Rel transcription factor and B-cell proliferation: a deal with the devil | Q28241767 | ||
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera | Q28241887 | ||
Signaling to NF-kappaB | Q29547844 | ||
Missing pieces in the NF-kappaB puzzle | Q29547864 | ||
NF-kappaB in cancer: from innocent bystander to major culprit | Q29614603 | ||
A phase 2 study of bortezomib in relapsed, refractory myeloma | Q33348702 | ||
Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma | Q33364240 | ||
Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies | Q33364359 | ||
Reactive oxygen signaling and MAPK activation distinguish Epstein-Barr Virus (EBV)-positive versus EBV-negative Burkitt's lymphoma | Q33714992 | ||
Cellular origin of human B-cell lymphomas. | Q33772424 | ||
Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases | Q33777633 | ||
Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel | Q33797168 | ||
Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases | Q33797174 | ||
Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades | Q34086191 | ||
Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes | Q44394144 | ||
Effect of NF-kappaB/Rel inhibition on spontaneous vs chemotherapy-induced apoptosis in AML and normal cord blood CD34+ cells | Q44452187 | ||
Mechanisms of Bcr-Abl-mediated NF-kappaB/Rel activation | Q44492984 | ||
Bortezomib | Q44542821 | ||
Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis | Q44834826 | ||
Targeting NF-kappaB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells. | Q45083325 | ||
AT514, a cyclic depsipeptide from Serratia marcescens, induces apoptosis of B-chronic lymphocytic leukemia cells: interference with the Akt/NF-kappaB survival pathway. | Q45296438 | ||
Enhancement of cytosine arabinoside-induced apoptosis in human myeloblastic leukemia cells by NF-kappa B/Rel- specific decoy oligodeoxynucleotides | Q45869627 | ||
Rapamycin stimulates apoptosis of childhood acute lymphoblastic leukemia cells | Q46477311 | ||
Bortezomib or high-dose dexamethasone for relapsed multiple myeloma | Q46549268 | ||
The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status | Q46706369 | ||
Expression of FLIPLong and FLIPShort in bone marrow mononuclear and CD34+ cells in patients with myelodysplastic syndrome: correlation with apoptosis | Q47439811 | ||
Apoptotic resistance to ionizing radiation in pediatric B-precursor acute lymphoblastic leukemia frequently involves increased NF-kappaB survival pathway signaling. | Q47606126 | ||
The 4th nation-wide study of adult T-cell leukemia/lymphoma (ATL) in Japan: estimates of risk of ATL and its geographical and clinical features. The T- and B-cell Malignancy Study Group | Q50553300 | ||
Mutational analysis of the N-ras gene in acute lymphoblastic leukemia: a study of 125 Japanese pediatric cases | Q50871661 | ||
Expression of IAP family proteins in myelodysplastic syndromes transforming to overt leukemia. | Q52087420 | ||
The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma. | Q53931762 | ||
Variable frequencies of t(11;18)(q21;q21) in MALT lymphomas of different sites: significant association with CagA strains of H pylori in gastric MALT lymphoma. | Q54780176 | ||
MALT lymphoma: from morphology to molecules | Q57369685 | ||
Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response | Q57374967 | ||
Expression of the NF-κB targets BCL2 and BIRC5/Survivin characterizes small B-cell and aggressive B-cell lymphomas, respectively | Q58010962 | ||
Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia | Q58042064 | ||
Constitutive NF-κB/Rel Activation in Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia (ALL) | Q58414426 | ||
Quinine improves results of intensive chemotherapy (IC) in myelodysplastic syndromes (MDS) expressing P-glycoprotein (PGP). Updated results of a randomized study. Groupe Français des Myélodysplasies (GFM) and Groupe GOELAMS | Q73028075 | ||
Detection by the fluorescence in situ hybridization technique of MYC translocations in paraffin-embedded lymphoma biopsy samples | Q73204017 | ||
Modulation of NF-kappa B activity and apoptosis in chronic lymphocytic leukemia B cells | Q73407146 | ||
Expression and prognostic significance of Bcl-2 family proteins in myelodysplastic syndromes | Q74447420 | ||
Increased IkappaB kinase activity is associated with activated NF-kappaB in acute myeloid blasts | Q78306906 | ||
Autocrine VEGF mediates the antiapoptotic effect of CD154 on CLL cells | Q81326791 | ||
Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule. | Q34250209 | ||
Signaling pathways activated by daunorubicin | Q34330164 | ||
Preferential induction of apoptosis for primary human leukemic stem cells | Q34415832 | ||
Identification of a tumor-associated mutant form of the NF-kappaB RelA gene with reduced DNA-binding and transactivating activities | Q34417654 | ||
Classical Hodgkin lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2. | Q34520814 | ||
NF-kappaB and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDSs) | Q34560200 | ||
Novel therapeutic approaches for multiple myeloma | Q35170935 | ||
A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation | Q35195588 | ||
NF-kappaB/Rel-mediated regulation of apoptosis in hematologic malignancies and normal hematopoietic progenitors. | Q35566335 | ||
Part I: Hodgkin's lymphoma--molecular biology of Hodgkin and Reed-Sternberg cells | Q35618780 | ||
The IKK NF-kappa B system: a treasure trove for drug development | Q35621375 | ||
Nuclear factor-kappaB: the enemy within | Q35893620 | ||
Proteasome inhibition as a novel therapeutic target in human cancer. | Q36014046 | ||
Myeloproliferative disorders: the centrosome connection | Q36233843 | ||
Properties of thalidomide and its analogues: implications for anticancer therapy | Q36250757 | ||
Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells | Q36369816 | ||
Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma | Q36375732 | ||
c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis | Q36399443 | ||
The human T-lymphotropic virus type I tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells | Q36714886 | ||
Potentiation of tumour apoptosis by human growth hormone via glutathione production and decreased NF-kappaB activity | Q38306010 | ||
Identification of NF-kappa B-regulated genes induced by TNFalpha utilizing expression profiling and RNA interference | Q38355972 | ||
NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells | Q38358712 | ||
Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells | Q39795545 | ||
NF-kappaB constitutes a potential therapeutic target in high-risk myelodysplastic syndrome | Q40362293 | ||
Curcumin suppresses constitutive activation of AP-1 by downregulation of JunD protein in HTLV-1-infected T-cell lines | Q40374653 | ||
Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large-cell, and other peripheral T-cell lymphomas | Q40381315 | ||
Constitutive NF-kappaB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity | Q40422412 | ||
NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes | Q40427138 | ||
Role for the nuclear factor kappaB pathway in transforming growth factor-beta1 production in idiopathic myelofibrosis: possible relationship with FK506 binding protein 51 overexpression | Q40434394 | ||
Transcriptional activation of survivin through the NF-kappaB pathway by human T-cell leukemia virus type I tax. | Q40454759 | ||
Chemosensitization by erythropoietin through inhibition of the NF-kappaB rescue pathway | Q40484626 | ||
Transcriptional activation of hTERT through the NF-kappaB pathway in HTLV-I-transformed cells | Q40540408 | ||
A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells. | Q40549559 | ||
Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells | Q40594673 | ||
Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma Cells | Q40633129 | ||
Malignant transformation of primary chicken spleen cells by human transcription factor c-Rel | Q40769231 | ||
Analysis of expression of nuclear factor kappa B (NF-kappa B) in multiple myeloma: downregulation of NF-kappa B induces apoptosis | Q40769452 | ||
NF-kappa B as a central mediator in the induction of TGF-beta in monocytes from patients with idiopathic myelofibrosis: an inflammatory response beyond the realm of homeostasis | Q40864312 | ||
B-cell lymphoma of MALT type: a review with special emphasis on diagnostic and management problems of low-grade gastric tumours | Q41694133 | ||
Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL | Q42139163 | ||
Expression of constitutively active nuclear-kappa B RelA transcription factor in blasts of acute myeloid leukemia | Q42457853 | ||
Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation | Q42795799 | ||
Inhibition of NF-kappa B activity by thalidomide through suppression of IkappaB kinase activity | Q43571541 | ||
Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells | Q43757315 | ||
Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications | Q44010411 | ||
The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis | Q44134125 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | NF-κB | Q411114 |
P304 | page(s) | 748-58 | |
P577 | publication date | 2006-05-01 | |
P1433 | published in | Cell Death & Differentiation | Q2943974 |
P1476 | title | Targeting NF-kappaB in hematologic malignancies | |
P478 | volume | 13 |
Q53562423 | 1,25-dihydroxyvitamin D3 induces biphasic NF-kappaB responses during HL-60 leukemia cells differentiation through protein induction and PI3K/Akt-dependent phosphorylation/degradation of IkappaB. |
Q40083731 | AKT/NF-kappaB inhibitor xanthohumol targets cell growth and angiogenesis in hematologic malignancies |
Q39905532 | ATM mediates constitutive NF-kappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia |
Q41514200 | Aberrant control of NF-κB in cancer permits transcriptional and phenotypic plasticity, to curtail dependence on host tissue: molecular mode |
Q59790131 | Ablation of miR-146b in mice causes hematopoietic malignancy |
Q41817444 | Allium compounds, dipropyl and dimethyl thiosulfinates as antiproliferative and differentiating agents of human acute myeloid leukemia cell lines. |
Q33692555 | Anticancer Role of PPARgamma Agonists in Hematological Malignancies Found in the Vasculature, Marrow, and Eyes. |
Q92906084 | Antitumor Mechanism of the Essential Oils from Two Succulent Plants in Multidrug Resistance Leukemia Cell |
Q46271548 | Apoptosis Induced by the Curcumin Analogue EF-24 Is Neither Mediated by Oxidative Stress-Related Mechanisms nor Affected by Expression of Main Drug Transporters ABCB1 and ABCG2 in Human Leukemia Cells. |
Q33706374 | BIIB021, an Hsp90 inhibitor, effectively kills a myelodysplastic syndrome cell line via the activation of caspases and inhibition of PI3K/Akt and NF-κB pathway proteins |
Q39503233 | Bioimaging analysis of nuclear factor-κB activity in Philadelphia chromosome-positive acute lymphoblastic leukemia cells reveals its synergistic upregulation by tumor necrosis factor-α-stimulated changes to the microenvironment |
Q37729639 | CCL5 as a potential immunotherapeutic target in triple-negative breast cancer |
Q35220648 | CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia |
Q42645448 | Canonical NFκB signaling in myeloid cells is required for the glioblastoma growth |
Q42144840 | Clinical and prognostic significance of miR-155 and miR-146a expression levels in formalin-fixed/paraffin-embedded tissue of patients with diffuse large B-cell lymphoma |
Q53268774 | Cudrania tricupidata bureau (CTB) glycoprotein inhibits proliferation by Di(2-ethylhexyl) phthalate in primary splenocytes: responses in cell proliferation signaling. |
Q36739771 | Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes |
Q41983972 | Cytotoxic effects of caffeic acid undecyl ester are involved in the inhibition of telomerase activity in NALM-6 human B-cell leukemia cells |
Q36722779 | Deregulated Levels of the NF-κB1, NF-κB2, and Rel Genes in Ukrainian Patients with Leukemia and Lymphoma in the Post-Chernobyl Period |
Q27692033 | Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms |
Q24682686 | Elevated NF-kappaB responses and FLIP levels in leukemic but not normal lymphocytes: reduction by salicylate allows TNF-induced apoptosis |
Q39681344 | Elevation of cyclic AMP causes an imbalance between NF-kappaB and p53 in NALM-6 cells treated by doxorubicin. |
Q90781411 | Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome |
Q33518536 | Ethacrynic acid exhibits selective toxicity to chronic lymphocytic leukemia cells by inhibition of the Wnt/beta-catenin pathway |
Q39650247 | Frequency of inherited variants in the MEFV gene in myelodysplastic syndrome and acute myeloid leukemia |
Q40139344 | Glutathione supplementation potentiates hypoxic apoptosis by S-glutathionylation of p65-NFkappaB. |
Q35163232 | High Frequency of Inherited Variants in the MEFV Gene in Acute Lymphocytic Leukemia |
Q34693392 | High concentrations of L-ascorbic acid specifically inhibit the growth of human leukemic cells via downregulation of HIF-1α transcription. |
Q40359750 | High frequency of MEFV gene mutations in patients with myeloid neoplasm |
Q37997663 | High frequency of inherited variants in the MEFV gene in patients with hematologic neoplasms: a genetic susceptibility? |
Q38335675 | Human lysosomal α-D-mannosidase regulation in promyelocytic leukaemia cells. |
Q31037798 | Hyperforin inhibits Akt1 kinase activity and promotes caspase-mediated apoptosis involving Bad and Noxa activation in human myeloid tumor cells |
Q54557849 | Imatinib treatment inhibit IL-6, IL-8, NF-KB and AP-1 production and modulate intracellular calcium in CML patients. |
Q38712967 | Induction of Apoptosis by Berberine in Hepatocellular Carcinoma HepG2 Cells via Downregulation of NF-κB. |
Q40219923 | Inhibition of NEMO, the regulatory subunit of the IKK complex, induces apoptosis in high-risk myelodysplastic syndrome and acute myeloid leukemia |
Q45290867 | Inhibition of nuclear factor kappa B activation in early-stage chronic lymphocytic leukemia by omega-3 fatty acids |
Q24315943 | Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation |
Q47107765 | Lp16-PSP, a Member of YjgF/YER057c/UK114 Protein Family Induces Apoptosis and p21WAF1/CIP1 Mediated G1 Cell Cycle Arrest in Human Acute Promyelocytic Leukemia (APL) HL-60 Cells. |
Q40141260 | Maspin augments proteasome inhibitor-induced apoptosis in prostate cancer cells |
Q37062143 | Mechanisms of SHP-1 P2 promoter regulation in hematopoietic cells and its silencing in HTLV-1-transformed T cells |
Q35220370 | MicroRNA function in myeloid biology |
Q37928982 | MicroRNA-146a and hemopoietic disorders |
Q35051303 | Microparticles induce multifactorial resistance through oncogenic pathways independently of cancer cell type. |
Q35022054 | NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies |
Q40184826 | NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia |
Q36351111 | NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity |
Q37790694 | NF-κB as a potential therapeutic target in myelodysplastic syndromes and acute myeloid leukemia |
Q38281185 | NF-κB suppresses ROS levels in BCR-ABL(+) cells to prevent activation of JNK and cell death |
Q91970526 | NT157 has antineoplastic effects and inhibits IRS1/2 and STAT3/5 in JAK2V617F-positive myeloproliferative neoplasm cells |
Q92519602 | Novel Targeted Nano-Parthenolide Molecule against NF-kB in Acute Myeloid Leukemia |
Q37514072 | Nucleophosmin Mutations Induce Chemosensitivity in THP-1 Leukemia Cells by Suppressing NF-κB Activity and Regulating Bax/Bcl-2 Expression |
Q42911212 | Pathological adaptive responses of Schwann cells to endoplasmic reticulum stress in bortezomib‐induced peripheral neuropathy |
Q33461888 | Polymorphisms in NF-kappaB inhibitors and risk of epithelial ovarian cancer |
Q27009841 | Protein glutathionylation in cardiovascular diseases |
Q41726404 | Regulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence. |
Q28481652 | Selective cytotoxicity of amidinopiperidine based compounds towards Burkitt's lymphoma cells involves proteasome inhibition |
Q38944398 | Targeting Thioredoxin-1 by dimethyl fumarate induces ripoptosome-mediated cell death |
Q41842515 | The Interface between BCR-ABL-Dependent and -Independent Resistance Signaling Pathways in Chronic Myeloid Leukemia. |
Q95650650 | The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges |
Q40162776 | The proteasome inhibitors bortezomib and PR-171 have antiproliferative and proapoptotic effects on primary human acute myeloid leukaemia cells |
Q38211084 | The role of inflammation in leukaemia |
Q38161353 | The role of nrf2 and cytoprotection in regulating chemotherapy resistance of human leukemia cells |
Q37103852 | The therapeutic potential of the proteasome in leukaemia |
Q93341036 | Vitamin E δ-tocotrienol inhibits TNF-α-stimulated NF-κB activation by up-regulation of anti-inflammatory A20 via modulation of sphingolipid including elevation of intracellular dihydroceramides |
Q26827754 | When ubiquitin meets NF-κB: a trove for anti-cancer drug development |
Q34245279 | microRNA regulation of inflammatory responses |
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