Martin Weik

researcher

Born 1968-01-01

Martin Weik is …
instance of (P31):
humanQ5

External links are
P2381Academic Tree ID693317
P6178Dimensions author ID01012747443.00
P269IdRef ID11026486X
P213ISNI0000000357676290
P496ORCID iD0000-0001-9297-642X
P3829Publons author ID2073945
P1053ResearcherIDM-2770-2017
P10861Springer Nature person ID01012747443.00
P214VIAF ID197963882

P166award receivedEBSA Young Investigators’ Medal and PrizeQ106646588
P185doctoral studentJacques-Philippe ColletierQ28321251
Gianluca SantoniQ58233083
P735given nameMartinQ18002399
MartinQ18002399
P106occupationresearcherQ1650915
P21sex or gendermaleQ6581097

Reverse relations

doctoral advisor (P184)
Q58233083Gianluca Santoni
Q28321251Jacques-Philippe Colletier

author (P50)
Q27683567300-Fold Increase in Production of the Zn2+-Dependent Dechlorinase TrzN in Soluble Form via Apoenzyme Stabilization
Q58044116A Polymer Surfactant Corona Dynamically Replaces Water in Solvent-Free Protein Liquids and Ensures Macromolecular Flexibility and Activity
Q27648776Activity, stability and structural studies of lactate dehydrogenases adapted to extreme thermal environments
Q27667894Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulations
Q33412072Can soaked-in scavengers protect metalloprotein active sites from reduction during data collection?
Q47277372Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography
Q60228225Coincidence of Dynamical Transitions in a Soluble Protein and Its Hydration Water: Direct Measurements by Neutron Scattering and MD Simulations
Q41621467Colouring cryo-cooled crystals: online microspectrophotometry.
Q53276945Conformational flexibility in the peripheral site of Torpedo californica acetylcholinesterase revealed by the complex structure with a bifunctional inhibitor.
Q33358518Correlation of the dynamics of native human acetylcholinesterase and its inhibited huperzine A counterpart from sub-picoseconds to nanoseconds
Q27638545Cryophotolysis of caged compounds: a technique for trapping intermediate states in protein crystals
Q27656774Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime
Q125341245De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals
Q87620231Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase
Q41831580Dielectric and calorimetric studies of hydrated purple membrane
Q42596435Direct correlation between molecular dynamics and enzymatic stability: a comparative neutron scattering study of native human butyrylcholinesterase and its "aged" soman conjugate.
Q36071932Dynamical coupling of intrinsically disordered proteins and their hydration water: comparison with folded soluble and membrane proteins
Q46530959Dynamical heterogeneity of specific amino acids in bacteriorhodopsin
Q42575201Dynamics of hydration water in deuterated purple membranes explored by neutron scattering
Q42101924Effects of soman inhibition and of structural differences on cholinesterase molecular dynamics: a neutron scattering study.
Q85550984Energy landscapes of human acetylcholinesterase and its Huperzine A-inhibited counterpart
Q57998475Evidence for the formation of disulfide radicals in protein crystals upon X-ray irradiation
Q27704310Evolution of Protein Quaternary Structure in Response to Selective Pressure for Increased Thermostability
Q36838929Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics
Q43026294From shell to cell: neutron scattering studies of biological water dynamics and coupling to activity.
Q27675368Huprine derivatives as sub-nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X-ray crystallography
Q30940142Hydration water mobility is enhanced around tau amyloid fibers
Q43081937Induced-fit or preexisting equilibrium dynamics? Lessons from protein crystallography and MD simulations on acetylcholinesterase and implications for structure-based drug design
Q30400443Infrared protein crystallography.
Q27683805Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry
Q83088044Kinetic insight into the mechanism of cholinesterasterase inhibition by aflatoxin B1 to develop biosensors
Q90427937Ligand pathways in neuroglobin revealed by low-temperature photodissociation and docking experiments
Q61806896Light-induced structural changes in a full-length cyanobacterial phytochrome probed by time-resolved X-ray scattering
Q47858594Localization of glycolipids in membranes by in vivo labeling and neutron diffraction.
Q34398608Long route or shortcut? A molecular dynamics study of traffic of thiocholine within the active-site gorge of acetylcholinesterase
Q30367499Low-dose X-ray radiation induces structural alterations in proteins.
Q35685221Low-temperature behavior of water confined by biological macromolecules and its relation to protein dynamics.
Q34878135Macromolecular crystallography radiation damage research: what's new?
Q27704914Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography
Q27644034Mechanisms of cholinesterase inhibition by inorganic mercury
Q40560240Molecular Dynamics Simulations of a Powder Model of the Intrinsically Disordered Protein Tau.
Q39488264Neutrons describe ectoine effects on water H-bonding and hydration around a soluble protein and a cell membrane
Q52354346Photochemical Mechanism of an Atypical Algal Phytochrome.
Q89582515Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy
Q53841532Porin self-association enables cell-to-cell contact in Providencia stuartii floating communities.
Q52315544Potent 3-hydroxy-2-pyridine aldoxime reactivators of organophosphate-inhibited cholinesterases with predicted blood-brain barrier penetration.
Q60228218Protein Surface and Core Dynamics Show Concerted Hydration-Dependent Activation
Q35079664Protein dynamics studied by neutron scattering.
Q36390375Radiation Damage in Macromolecular Crystallography.
Q89663730Radiation damage and dose limits in serial synchrotron crystallography at cryo- and room temperatures
Q44282687Radiation damage to biological macromolecules: some answers and more questions.
Q35569008Radiation damage to macromolecules: kill or cure?
Q27665826Raman-assisted crystallography suggests a mechanism of X-ray-induced disulfide radical formation and reparation
Q27667321Reaction of Cresyl Saligenin Phosphate, the Organophosphorus Agent Implicated in Aerotoxic Syndrome, with Human Cholinesterases: Mechanistic Studies Employing Kinetics, Mass Spectrometry, and X-ray Structure Analysis
Q46551068Reaction site-driven regioselective synthesis of AChE inhibitors
Q42716156Relation between dynamics, activity and thermal stability within the cholinesterase family.
Q27704003Serial Femtosecond Crystallography and Ultrafast Absorption Spectroscopy of the Photoswitchable Fluorescent Protein IrisFP
Q89983245Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade
Q27651567Shoot-and-Trap: Use of specific x-ray damage to study structural protein dynamics by temperature-controlled cryo-crystallography
Q45349749Similarities and differences in radiation damage at 100 K versus 160 K in a crystal of thermolysin.
Q37279432Simultaneous measurements of solvent dynamics and functional kinetics in a light-activated enzyme.
Q27670515Snapshots of Enzymatic Baeyer-Villiger Catalysis: OXYGEN ACTIVATION AND INTERMEDIATE STABILIZATION
Q52066685Solvent behaviour in flash-cooled protein crystals at cryogenic temperatures.
Q27621012Specific chemical and structural damage to proteins produced by synchrotron radiation
Q28359775Specific protein dynamics near the solvent glass transition assayed by radiation-induced structural changes
Q27643494Specific radiation damage to acidic residues and its relation to their chemical and structural environment
Q41444745Structural insights into substrate traffic and inhibition in acetylcholinesterase
Q27678479Structure and function of an insect  -carboxylesterase ( Esterase7) associated with insecticide resistance
Q74186457Structure and hydration of the M-state of the bacteriorhodopsin mutant D96N studied by neutron diffraction
Q81667283Supercooled liquid-like solvent in trypsin crystals: implications for crystal annealing and temperature-controlled X-ray radiation damage studies
Q34185708Temperature derivative fluorescence spectroscopy as a tool to study dynamical changes in protein crystals.
Q39968728Temperature-dependent macromolecular X-ray crystallography.
Q40281590The influence of solvent composition on global dynamics of human butyrylcholinesterase powders: a neutron-scattering study.
Q45797540The low-temperature inflection observed in neutron scattering measurements of proteins is due to methyl rotation: direct evidence using isotope labeling and molecular dynamics simulations.
Q27728043The role of protein dynamics in the evolution of new enzyme function
Q41917487Translational diffusion of hydration water correlates with functional motions in folded and intrinsically disordered proteins
Q27649071Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography
Q39068927X-ray radiation damage to biological macromolecules: further insights