Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling

scientific article

Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1006383674
P356DOI10.1186/1742-2094-11-47
P932PMC publication ID3995780
P698PubMed publication ID24618100
P5875ResearchGate publication ID260716634

P2093author name stringJian-Hong Zhu
Juan-Juan Zhu
Ming Zou
Xiong Zhang
Li-Li Zhou
Jian-Yong Wang
Rong-Pei Liu
Jun-Mei Lai
Song-Fang Chen
P2860cites workCyclic stretch stimulates vascular smooth muscle cell alignment by redox-dependent activation of Notch3Q23914856
The NF-kappa B and I kappa B proteins: new discoveries and insightsQ24313579
From inflammation to sickness and depression: when the immune system subjugates the brainQ24633527
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced deathQ24644712
Nitric oxide and peroxynitrite in health and diseaseQ24645400
Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clonesQ28285883
Involvement of the intracellular ion channel CLIC1 in microglia-mediated beta-amyloid-induced neurotoxicityQ28575185
Microglia-mediated neurotoxicity: uncovering the molecular mechanismsQ29547835
Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brainsQ29616293
Mechanisms underlying inflammation in neurodegenerationQ29617977
Nitric oxide synthases: Roles, tolls, and controlsQ29618629
Activation of murine microglial cell lines by lipopolysaccharide and interferon-gamma causes NO-mediated decreases in mitochondrial and cellular function.Q31900371
Selective serotonin reuptake inhibitors versus tricyclic and heterocyclic antidepressants: comparison of drug adherenceQ34062430
Fcgamma receptor I- and III-mediated macrophage inflammatory protein 1alpha induction in primary human and murine microgliaQ34130404
A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microgliaQ34247698
The Role of Inflammatory Cytokines in Cognition and Other Non-Motor Symptoms of Parkinson's DiseaseQ34330121
The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depressionQ34904703
Specific PKC isoforms regulate LPS-stimulated iNOS induction in murine microglial cellsQ35031301
The AGNP-TDM Expert Group Consensus Guidelines: focus on therapeutic monitoring of antidepressants.Q35236618
Inflammation and neurodegeneration in Parkinson's diseaseQ35756452
Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression.Q36692860
Intrastriatal lipopolysaccharide injection induces parkinsonism in C57/B6 miceQ37217248
Evidence for a cytokine model of cognitive functionQ37321439
Microglia: gatekeepers of central nervous system immunology.Q37333298
The multiple roles of the innate immune system in the regulation of apoptosis and inflammation in the brainQ37395741
Inflammation in neurodegenerative diseasesQ37766302
Depression in Parkinson disease--epidemiology, mechanisms and management.Q37971293
Anti-inflammatory effects of fluoxetine in lipopolysaccharide(LPS)-stimulated microglial cellsQ39541722
LPS-induced iNOS expression in Bv-2 cells is suppressed by an oxidative mechanism acting on the JNK pathway--a potential role for neuroprotectionQ39742584
Celastrol inhibits production of nitric oxide and proinflammatory cytokines through MAPK signal transduction and NF-kappaB in LPS-stimulated BV-2 microglial cellsQ40030520
Distinct signaling pathways for induction of type II NOS by IFNgamma and LPS in BV-2 microglial cells.Q40410055
Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1 beta productionQ40580069
Effect of sesame antioxidants on LPS-induced NO production by BV2 microglial cellsQ40627929
Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nitric oxide, IL-1beta, TNF-alpha and IL-6 in an in-vitro model of brain inflammationQ40891679
Induction of adenylate cyclase sensitive dopamine D2-receptors in retinoic acid induced differentiated human neuroblastoma SHSY-5Y cellsQ41052317
Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB, JAK-STAT and JNK stress kinase pathways.Q42701827
Paroxetine prevents loss of nigrostriatal dopaminergic neurons by inhibiting brain inflammation and oxidative stress in an experimental model of Parkinson's diseaseQ43010410
Behavior, neurochemistry and histology after intranigral lipopolysaccharide injection.Q43945450
Silymarin protects dopaminergic neurons against lipopolysaccharide-induced neurotoxicity by inhibiting microglia activation.Q44242988
Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra.Q46729659
TLR signaling tailors innate immune responses in human microglia and astrocytesQ57041985
Tolerability of paroxetine in Parkinson's disease: A prospective studyQ57203470
Paroxetine in Parkinson's disease: effects on motor and depressive symptomsQ64765320
Elevated plasma nitrate levels in depressive statesQ73605617
Double null of selenium-glutathione peroxidase-1 and copper, zinc-superoxide dismutase enhances resistance of mouse primary hepatocytes to acetaminophen toxicityQ83195630
Inflammation in Parkinson's disease: cause or consequence?Q84582822
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectlipopolysaccharideQ421804
microgliaQ1622829
P304page(s)47
P577publication date2014-03-12
P1433published inJournal of NeuroinflammationQ15716679
P1476titleParoxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling
P478volume11

Reverse relations

cites work (P2860)
Q37310521A Potential Contribution of Chemokine Network Dysfunction to the Depressive Disorders
Q90464502Advanced oxidation protein products induce microglia-mediated neuroinflammation via MAPKs-NF-κB signaling pathway and pyroptosis after secondary spinal cord injury
Q46627623Anti-inflammatory properties of tianeptine on lipopolysaccharide-induced changes in microglial cells involve toll-like receptor-related pathways
Q35179051Antidepressant compounds can be both pro- and anti-inflammatory in human hippocampal cells
Q36437932Antidepressants Impact Connexin 43 Channel Functions in Astrocytes
Q47642074Antidepressants, sertraline and paroxetine, increase calcium influx and induce mitochondrial damage-mediated apoptosis of astrocytes
Q58750811Differential Regulation of Adhesion and Phagocytosis of Resting and Activated Microglia by Dopamine
Q35190346EP2-PKA signaling is suppressed by triptolide in lipopolysaccharide-induced microglia activation
Q39600299Effects of a Standardized Phenolic-Enriched Maple Syrup Extract on β-Amyloid Aggregation, Neuroinflammation in Microglial and Neuronal Cells, and β-Amyloid Induced Neurotoxicity in Caenorhabditis elegans
Q36667043GLP-2 Attenuates LPS-Induced Inflammation in BV-2 Cells by Inhibiting ERK1/2, JNK1/2 and NF-κB Signaling Pathways.
Q37310533Inflammation and Immune Regulation as Potential Drug Targets in Antidepressant Treatment.
Q57285359Neuroimmunomodulation in Major Depressive Disorder: Focus on Caspase 1, Inducible Nitric Oxide Synthase, and Interferon-Gamma
Q61453845Norfluoxetine Prevents Degeneration of Dopamine Neurons by Inhibiting Microglia-Derived Oxidative Stress in an MPTP Mouse Model of Parkinson's Disease
Q89554264Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes
Q47940043Propofol attenuates BV2 microglia inflammation via NMDA receptor inhibition
Q64859345Raf kinase inhibitor protein protects microglial cells against 1-methyl-4-phenylpyridinium-induced neuroinflammation in vitro
Q26748711Repurposing psychiatric medicines to target activated microglia in anxious mild cognitive impairment and early Parkinson's disease
Q60445723Targeting the NLRP3 Inflammasome-Related Pathways via Tianeptine Treatment-Suppressed Microglia Polarization to the M1 Phenotype in Lipopolysaccharide-Stimulated Cultures
Q48430028Th17 Cells Induce Dopaminergic Neuronal Death via LFA-1/ICAM-1 Interaction in a Mouse Model of Parkinson's Disease
Q38670012The implication of neuronimmunoendocrine (NIE) modulatory network in the pathophysiologic process of Parkinson's disease
Q35602606The role of the kynurenine pathway in suicidality in adolescent major depressive disorder
Q41850897Trazodone regulates neurotrophic/growth factors, mitogen-activated protein kinases and lactate release in human primary astrocytes
Q37690930Vanillin Protects Dopaminergic Neurons against Inflammation-Mediated Cell Death by Inhibiting ERK1/2, P38 and the NF-κB Signaling Pathway

Search more.