review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Frank Martin Schmidt | Q48202494 |
Nicole Lichtblau | Q84560342 | ||
P2093 | author name string | Kenneth C Kirkby | |
P2860 | cites work | So depression is an inflammatory disease, but where does the inflammation come from? | Q21245291 |
Meta-Analysis of the Effects of Eicosapentaenoic Acid (EPA) in Clinical Trials in Depression | Q22305455 | ||
Pharmacologic treatment of depression in multiple sclerosis | Q24236534 | ||
Benefits from antidepressants: synthesis of 6-week patient-level outcomes from double-blind placebo-controlled randomized trials of fluoxetine and venlafaxine | Q24607720 | ||
Antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans | Q24627318 | ||
Omega-3 fatty acids for the treatment of depression: systematic review and meta-analysis | Q24634019 | ||
Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways | Q26823313 | ||
Immune and neurotrophin stimulation by electroconvulsive therapy: is some inflammation needed after all? | Q28080546 | ||
Aspirin and salicylates inhibit the IL-4- and IL-13-induced activation of STAT6 | Q28192195 | ||
Acetylsalicylic acid accelerates the antidepressant effect of fluoxetine in the chronic escape deficit model of depression | Q28217850 | ||
Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling | Q28384484 | ||
Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report | Q29615999 | ||
A meta-analysis of cytokines in major depression | Q29617325 | ||
Relevance of the anti-inflammatory properties of curcumin in neurodegenerative diseases and depression. | Q38290421 | ||
Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial. | Q38410039 | ||
Exercise as an augmentation treatment for nonremitted major depressive disorder: a randomized, parallel dose comparison | Q38489796 | ||
Inflammation and clinical response to treatment in depression: A meta-analysis | Q38546291 | ||
Therapeutic antidepressant potential of a conjugated siRNA silencing the serotonin transporter after intranasal administration | Q38552025 | ||
Psychopharmacological Agents and Suicide Risk Reduction: Ketamine and Other Approaches | Q38573810 | ||
TNFα mediates stress-induced depression by upregulating indoleamine 2,3-dioxygenase in a mouse model of unpredictable chronic mild stress | Q38600555 | ||
Impact of Serum Cytokine Levels on EEG-Measured Arousal Regulation in Patients with Major Depressive Disorder and Healthy Controls | Q38915949 | ||
Acetylsalicylic acid enhances the anti-inflammatory effect of fluoxetine through inhibition of NF-κB, p38-MAPK and ERK1/2 activation in lipopolysaccharide-induced BV-2 microglia cells | Q38982443 | ||
ABCB1 gene variants and antidepressant treatment outcome: A meta-analysis | Q39021015 | ||
The economic burden of adults with major depressive disorder in the United States (2005 and 2010). | Q39032685 | ||
The pro-inflammatory cytokine TNF-α regulates the activity and expression of the serotonin transporter (SERT) in astrocytes | Q39207029 | ||
Regulation of BCRP (ABCG2) and P-glycoprotein (ABCB1) by cytokines in a model of the human blood-brain barrier | Q39821262 | ||
Aspirin and statin use and the subsequent development of depression in men and women: Results from a longitudinal population-based study | Q40281365 | ||
Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids | Q40673400 | ||
Cytokines influence mRNA expression of cytochrome P450 3A4 and MDRI in intestinal cells | Q40814762 | ||
Retrospective pilot study for analysis of antidepressant serum concentrations of citalopram and venlafaxine during inflammation | Q41018162 | ||
Impact of lithium alone and in combination with antidepressants on cytokine production in vitro | Q41673145 | ||
Curcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase/Akt pathway | Q41786171 | ||
Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. | Q42431545 | ||
Astrocytic TNFα regulates the behavioral response to antidepressants | Q42466876 | ||
Effect of acute sleep deprivation and recovery on Insulin-like Growth Factor-I responses and inflammatory gene expression in healthy men. | Q42468148 | ||
Minocycline as adjunctive therapy for patients with unipolar psychotic depression: an open-label study | Q42637078 | ||
Fluoxetine Disposition in Patients with Chronic Hepatitis C Treated with Interferon-α | Q42869554 | ||
Antidepressant-like activity of the aqueous extract of Allium macrostemon in mice | Q42967915 | ||
Regulation of major efflux transporters under inflammatory conditions at the blood-brain barrier in vitro | Q43298284 | ||
Effects of ketamine/xylazine on expression of tumor necrosis factor-alpha, inducible nitric oxide synthase, and cyclo-oxygenase-2 in rat gastric mucosa during endotoxemia | Q43751104 | ||
Augmentation of fluoxetine with lovastatin for treating major depressive disorder, a randomized double-blind placebo controlled-clinical trial. | Q43790314 | ||
Antidepressant-like effect of oleanolic acid in mice exposed to the repeated forced swimming test | Q44133539 | ||
Plasma levels of TNF-alpha and IL-6 are inversely related to cytochrome P450-dependent drug metabolism in patients with congestive heart failure | Q44202038 | ||
Interleukine-6 serum levels correlate with response to antidepressant sleep deprivation and sleep phase advance | Q44229688 | ||
The antiinflammatory effects of ketamine in endotoxemic rats during moderate and mild hypothermia | Q44812772 | ||
Chronic administration of infliximab (TNF-α inhibitor) decreases depression and anxiety-like behaviour in rat model of chronic mild stress. | Q46020755 | ||
Cytochrome P450 mRNA expression in peripheral blood lymphocytes as a predictor of enzyme induction | Q46616703 | ||
Cytokine profiles in women with different subtypes of major depressive disorder. | Q46866569 | ||
Pro-inflammatory cytokines and treatment response to escitalopram in major depressive disorder | Q46919296 | ||
Lack of association between depressive symptoms and markers of immune and vascular inflammation in middle-aged men and women | Q47344631 | ||
Ketamine-mediated alleviation of electroconvulsive shock-induced memory impairment is associated with the regulation of neuroinflammation and soluble amyloid-beta peptide in depressive-like rats | Q47703957 | ||
Ketamine reduces LPS-induced HMGB1 via activation of the Nrf2/HO-1 pathway and NF-κB suppression | Q47730927 | ||
Serum interleukin-6 is a predictive biomarker for ketamine's antidepressant effect in treatment-resistant patients with major depression. | Q47832529 | ||
Chronic Supplementation of Curcumin Enhances the Efficacy of Antidepressants in Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Pilot Study | Q48080795 | ||
Simvastatin as an adjuvant therapy to fluoxetine in patients with moderate to severe major depression: A double-blind placebo-controlled trial | Q48086898 | ||
Meta-Analysis of Cytokines and Chemokines in Suicidality: Distinguishing Suicidal Versus Nonsuicidal Patients | Q48145336 | ||
Curcumin and major depression: a randomised, double-blind, placebo-controlled trial investigating the potential of peripheral biomarkers to predict treatment response and antidepressant mechanisms of change | Q48149398 | ||
The TNF-alpha inhibitor etanercept as monotherapy in treatment-resistant depression - report of two cases. | Q48219182 | ||
Effects of sleep deprivation on nocturnal cytokine concentrations in depressed patients and healthy control subjects | Q48219570 | ||
An inflammatory biomarker as a differential predictor of outcome of depression treatment with escitalopram and nortriptyline | Q48255615 | ||
Indoleamine 2,3-dioxygenase and immune changes under antidepressive treatment in major depression in females | Q48263235 | ||
The influence of mianserin on TNF-α, IL-6 and IL-10 serum levels in rats under chronic mild stress | Q48278838 | ||
Electroconvulsive therapy exerts mainly acute molecular changes in serum of major depressive disorder patients. | Q48279124 | ||
The plasma levels of various cytokines are increased during ongoing depression and are reduced to normal levels after recovery | Q48291064 | ||
Cytokine levels in depressed and non-depressed subjects, and masking effects of obesity | Q48292772 | ||
Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier | Q48355279 | ||
The interleukin 1 beta (IL1B) gene is associated with failure to achieve remission and impaired emotion processing in major depression. | Q48359564 | ||
Successful antidepressant therapy restores the disturbed interplay between TNF-alpha system and HPA axis | Q48416386 | ||
Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial. | Q48452876 | ||
Early responses to deep brain stimulation in depression are modulated by anti-inflammatory drugs. | Q48469586 | ||
Plasma levels of tumor necrosis factor alpha and soluble tumor necrosis factor receptors in patients with narcolepsy | Q48490128 | ||
Shift of monocyte function toward cellular immunity during sleep. | Q48490177 | ||
Antidepressant effects of TNF-α blockade in an animal model of depression | Q48521076 | ||
Higher plasma interleukin-6 (IL-6) level is associated with SSRI- or SNRI-refractory depression | Q48682375 | ||
Effect of celecoxib add-on treatment on symptoms and serum IL-6 concentrations in patients with major depressive disorder: randomized double-blind placebo-controlled study | Q48695277 | ||
Is Glycogen Synthase Kinase-3 a Central Modulator in Mood Regulation? | Q30475816 | ||
n-3 fatty acids, inflammation and immunity: new mechanisms to explain old actions | Q30625279 | ||
A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers | Q33587452 | ||
Efficacy and safety of electroconvulsive therapy in depressive disorders: a systematic review and meta-analysis | Q33964983 | ||
Cytokine activation of the HPA axis. | Q34194915 | ||
The endocrinology of exercise | Q34332068 | ||
Effectiveness and tolerance of anti-inflammatory drugs' add-on therapy in major mental disorders: a systematic qualitative review | Q34384181 | ||
Unintended effects of statins from observational studies in the general population: systematic review and meta-analysis | Q34411415 | ||
Effect of anti-inflammatory treatment on depression, depressive symptoms, and adverse effects: a systematic review and meta-analysis of randomized clinical trials | Q34443846 | ||
A Randomized Sham-Controlled Trial of Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Chronic Treatment-Resistant Depression | Q34465029 | ||
Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review | Q34475595 | ||
Cumulative meta-analysis of interleukins 6 and 1β, tumour necrosis factor α and C-reactive protein in patients with major depressive disorder | Q34480323 | ||
Deep brain stimulation for depression: Scientific issues and future directions | Q34489637 | ||
Is there an association between peripheral immune markers and structural/functional neuroimaging findings? | Q34546439 | ||
Antioxidant and anti-inflammatory properties of curcumin | Q34580325 | ||
Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness | Q34626598 | ||
Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice. | Q34655648 | ||
Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial | Q34655680 | ||
Docosahexaenoic Acid Suppresses Neuroinflammatory Responses and Induces Heme Oxygenase-1 Expression in BV-2 Microglia: Implications of Antidepressant Effects for Omega-3 Fatty Acids | Q34660464 | ||
Minocycline treatment ameliorates interferon-alpha- induced neurogenic defects and depression-like behaviors in mice. | Q34667917 | ||
Antidepressant activity of curcumin: involvement of serotonin and dopamine system | Q34819911 | ||
Inflammatory cytokine-associated depression | Q34825010 | ||
Protocol and rationale-the efficacy of minocycline as an adjunctive treatment for major depressive disorder: a double blind, randomised, placebo controlled trial | Q34942602 | ||
Effects of sustained sleep restriction on mitogen-stimulated cytokines, chemokines and T helper 1/ T helper 2 balance in humans | Q35070171 | ||
Antidepressant compounds can be both pro- and anti-inflammatory in human hippocampal cells | Q35179051 | ||
Inflammatory cytokines in general and central obesity and modulating effects of physical activity | Q35187378 | ||
The effect of antidepressant medication treatment on serum levels of inflammatory cytokines: a meta-analysis | Q35356649 | ||
Celecoxib or naproxen treatment does not benefit depressive symptoms in persons age 70 and older: findings from a randomized controlled trial | Q35531978 | ||
Tlr4 upregulation in the brain accompanies depression- and anxiety-like behaviors induced by a high-cholesterol diet. | Q35567210 | ||
Markers of Oxidative Stress and Neuroprogression in Depression Disorder. | Q35677056 | ||
Therapeutic Developments Targeting Toll-like Receptor-4-Mediated Neuroinflammation | Q35681383 | ||
Inhibition of tumor necrosis factor improves sleep continuity in patients with treatment resistant depression and high inflammation. | Q35744195 | ||
Inflammation and depression: combined use of selective serotonin reuptake inhibitors and NSAIDs or paracetamol and psychiatric outcomes | Q36023793 | ||
Eicosapentaenoic acid appears to be the key omega-3 fatty acid component associated with efficacy in major depressive disorder: a critique of Bloch and Hannestad and updated meta-analysis | Q48701739 | ||
Imipramine and fluoxetine inhibit LPS-induced activation and affect morphology of microglial cells in the rat glial culture | Q48730285 | ||
Ustekinumab significantly improves symptoms of anxiety, depression, and skin-related quality of life in patients with moderate-to-severe psoriasis: Results from a randomized, double-blind, placebo-controlled phase III trial. | Q48818299 | ||
The effect of adalimumab on reducing depression symptoms in patients with moderate to severe psoriasis: a randomized clinical trial | Q48866081 | ||
Electroconvulsive therapy has acute immunological and neuroendocrine effects in patients with major depressive disorder | Q48942939 | ||
Different ratios of eicosapentaenoic and docosahexaenoic omega-3 fatty acids in commercial fish oils differentially alter pro-inflammatory cytokines in peritoneal macrophages from C57BL/6 female mice. | Q51813627 | ||
Increased serum IL-6 and IL-1 receptor antagonist concentrations in major depression and treatment resistant depression. | Q51996803 | ||
Paroxetine versus amitriptyline for treatment of depression associated with rheumatoid arthritis: a randomized, double blind, parallel group study. | Q52863302 | ||
Exercise treatment for depression | Q56536197 | ||
Negative Immunoregulatory Effects of Antidepressants Inhibition of Interferon-γ and Stimulation of Interleukin-10 Secretion | Q56767354 | ||
Soluble interleukin-2 receptor and tumor necrosis factor levels in depressed patients in Estonia | Q56783029 | ||
Regulatory T cells increased while IL-1β decreased during antidepressant therapy | Q57243415 | ||
Increase in Interleukin-1β in Late-Life Depression | Q57813826 | ||
Simvastatin inhibits the monocyte expression of proinflammatory cytokines in patients with hypercholesterolemia | Q58421218 | ||
Role of nitric oxide in the cytokine-mediated regulation of cytochrome P-450 | Q71061326 | ||
Cytokine production and treatment response in major depressive disorder | Q73505932 | ||
Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages | Q74529750 | ||
HMG-CoA reductase inhibition by atorvastatin reduces neointimal inflammation in a rabbit model of atherosclerosis | Q77700153 | ||
Inhibition of proinflammatory cytokine production by pravastatin | Q78165454 | ||
Raised plasma levels of tumor necrosis factor alpha in patients with depression: normalization during electroconvulsive therapy | Q79347499 | ||
Increase in plasma proinflammatory cytokines after electroconvulsive therapy in patients with depressive disorder | Q80988997 | ||
TNF activates P-glycoprotein in cerebral microvascular endothelial cells | Q81550792 | ||
A possible role to nitric oxide in the anti-inflammatory effects of amitriptyline | Q83155711 | ||
The antidepressive effects of exercise: a meta-analysis of randomized trials | Q83858845 | ||
The impact of social isolation on immunological parameters in rats | Q87240563 | ||
Statins as anti-inflammatory agents in atherogenesis: molecular mechanisms and lessons from the recent clinical trials. | Q36088110 | ||
Major depressive disorder: new clinical, neurobiological, and treatment perspectives | Q36096664 | ||
Are omega-3 fatty acids antidepressants or just mood-improving agents? The effect depends upon diagnosis, supplement preparation, and severity of depression | Q36417226 | ||
Pro-inflammatory cytokines as predictors of antidepressant effects of exercise in major depressive disorder | Q36438114 | ||
Glucocorticoids, cytokines and brain abnormalities in depression | Q36442019 | ||
Interferon-induced depression in chronic hepatitis C: a review of its prevalence, risk factors, biology, and treatment approaches. | Q36457583 | ||
A detailed examination of cytokine abnormalities in Major Depressive Disorder | Q36496289 | ||
Roles of nitric oxide in inflammatory downregulation of human cytochromes P450. | Q36593723 | ||
The rapid antidepressant effect of ketamine in rats is associated with down-regulation of pro-inflammatory cytokines in the hippocampus | Q36754254 | ||
The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression | Q36800963 | ||
Oleanolic acid acrylate elicits antidepressant-like effect mediated by 5-HT1A receptor | Q36972557 | ||
Cytokines and pathological sleep | Q37007014 | ||
Glycogen synthase kinase-3 regulates microglial migration, inflammation, and inflammation-induced neurotoxicity | Q37071441 | ||
Inflammatory cytokines in depression: neurobiological mechanisms and therapeutic implications | Q37089253 | ||
The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC. | Q37230649 | ||
Chronic deep brain stimulation of the hypothalamic nucleus in wistar rats alters circulatory levels of corticosterone and proinflammatory cytokines | Q37286251 | ||
Impact of antidepressants on cytokine production of depressed patients in vitro | Q37357893 | ||
Infections in children and adolescents with juvenile idiopathic arthritis and inflammatory bowel disease treated with tumor necrosis factor-α inhibitors: systematic review of the literature | Q37463702 | ||
Toll-like 4 receptor inhibitor TAK-242 decreases neuroinflammation in rat brain frontal cortex after stress | Q37498989 | ||
Cytokine signaling modulates blood-brain barrier function | Q37612092 | ||
A psychoneuroimmunological review on cytokines involved in antidepressant treatment response | Q37725843 | ||
CYP-mediated therapeutic protein-drug interactions: clinical findings, proposed mechanisms and regulatory implications | Q37729127 | ||
Toll-like receptors in the depressed and suicide brain | Q37731799 | ||
Effects of sleep and circadian rhythm on the human immune system. | Q37732356 | ||
A meta-analytic review of polyunsaturated fatty acid compositions in patients with depression | Q37746266 | ||
AGNP Consensus Guidelines for Therapeutic Drug Monitoring in Psychiatry: Update 2011. | Q37942066 | ||
New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates--Nrf2 activators and GSK-3 inhibitors. | Q37978196 | ||
Neuroplastic changes in depression: a role for the immune system | Q38004739 | ||
Targeting cyclooxygenase-2 in depression is not a viable therapeutic approach and may even aggravate the pathophysiology underpinning depression | Q38024740 | ||
The relationship between statins and depression: a review of the literature | Q38114474 | ||
CRP, IL-6 and depression: a systematic review and meta-analysis of longitudinal studies | Q38122795 | ||
The role of inflammatory cytokines in suicidal behavior: a systematic review | Q38125003 | ||
Cytokines as biomarkers in depressive disorder: current standing and prospects. | Q38154918 | ||
Oxidative & nitrosative stress in depression: why so much stress? | Q38214407 | ||
A critical review of the efficacy of non-steroidal anti-inflammatory drugs in depression. | Q38279498 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial | Q6936496 |
P433 | issue | 7 | |
P921 | main subject | antidepressant | Q76560 |
inflammation | Q101991 | ||
neurotic disorder | Q19000444 | ||
immunologic factor | Q50349184 | ||
P304 | page(s) | 674-687 | |
P577 | publication date | 2016-01-01 | |
P1433 | published in | Current Neuropharmacology | Q20181354 |
P1476 | title | Inflammation and Immune Regulation as Potential Drug Targets in Antidepressant Treatment | |
P478 | volume | 14 |
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