| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/S00228-005-0971-0 |
| P698 | PubMed publication ID | 16041547 |
| P50 | author | Reginald F. Frye | Q37370763 |
| P2093 | author name string | Brent M Booker | |
| Curtis E Haas | |||
| Daniel Brazeau | |||
| Thomas Kufel | |||
| Valerie Frerichs | |||
| Denise Cloen | |||
| Colleen Zaranek | |||
| P2860 | cites work | Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR | Q24290621 |
| The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions | Q24310512 | ||
| Detection of mRNA encoding xenobiotic-metabolizing cytochrome P450s in human bronchoalveolar macrophages and peripheral blood lymphocytes | Q28254139 | ||
| Expression of the CYP1A1 gene in peripheral lymphocytes as a marker of exposure to creosote in railroad workers | Q28342994 | ||
| An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A) | Q28365904 | ||
| Induction of CYP2C genes in human hepatocytes in primary culture | Q31956818 | ||
| Drug metabolizing enzymes in lymphocytes | Q33547008 | ||
| Fingerprinting of cytochrome P450 and microsomal epoxide hydrolase gene expression in human blood cells | Q33903302 | ||
| Phenotyping of drug-metabolizing enzymes in adults: a review of in-vivo cytochrome P450 phenotyping probes | Q33914036 | ||
| Noninvasive tests of CYP3A enzymes | Q34059919 | ||
| Interaction of omeprazole, lansoprazole and pantoprazole with P-glycoprotein | Q34107284 | ||
| Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes | Q34184221 | ||
| CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects. | Q34303365 | ||
| Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors | Q34429206 | ||
| The influence of enzyme induction on polymorphic sparteine oxidation | Q34447764 | ||
| Human lymphocyte cytochrome P450 2E1, a putative marker for alcohol-mediated changes in hepatic chlorzoxazone activity. | Q34448778 | ||
| Diabetes mellitus increases the in vivo activity of cytochrome P450 2E1 in humans | Q35825142 | ||
| Three new alternative splicing variants of human cytochrome P450 2D6 mRNA in human extratumoral liver tissue | Q36066145 | ||
| Detection of cytochrome P450 and other drug-metabolizing enzyme mRNAs in peripheral blood mononuclear cells using DNA arrays | Q38310452 | ||
| Recent Advances: the Cytochrome P450 Enzymes | Q40475823 | ||
| The use of caffeine for enzyme assays: a critical appraisal | Q40905946 | ||
| The use of caffeine as a metabolic probe for human drug metabolizing enzymes | Q41213881 | ||
| Genetic predisposition to bladder cancer: ability to hydroxylate debrisoquine and mephenytoin as risk factors | Q41463151 | ||
| The effect of rifampin treatment on intestinal expression of human MRP transporters | Q42048574 | ||
| Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva. | Q42281878 | ||
| Orphan receptor promiscuity in the induction of cytochromes p450 by xenobiotics | Q43559256 | ||
| Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin | Q43823777 | ||
| Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport | Q43908850 | ||
| Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism | Q44028974 | ||
| Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver | Q44042287 | ||
| Effect of sex and menstrual cycle phase on cytochrome P450 2C19 activity with omeprazole used as a biomarker | Q44110143 | ||
| Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis | Q44324967 | ||
| An evaluation of the suitability of intravenous midazolam as an in vivo marker for hepatic cytochrome P4503A activity | Q44351147 | ||
| Coordinated intrahepatic and extrahepatic regulation of cytochrome p4502D6 in healthy subjects and in patients after liver transplantation | Q44431084 | ||
| Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism | Q44447147 | ||
| Only truncated, not complete cytochrome p450 2D6 RNA transcript and no detectable enzyme activity are expressed in human lymphocytes | Q44550569 | ||
| Cytochrome p450 3A4 messenger ribonucleic acid induction by rifampin in human peripheral blood mononuclear cells: correlation with alprazolam pharmacokinetics | Q44637327 | ||
| Determination of CYP2C19 phenotype in black Americans with omeprazole: correlation with genotype | Q46621426 | ||
| Quantification of 3-month intraindividual variability and the influence of sex and menstrual cycle phase on CYP3A activity as measured by phenotyping with intravenous midazolam. | Q50864245 | ||
| Methodologies to study the induction of rat hepatic and intestinal cytochrome P450 3A at the mRNA, protein, and catalytic activity level. | Q51372283 | ||
| Combined phenotypic assessment of CYP1A2, CYP2C19, CYP2D6, CYP3A, N-acetyltransferase-2, and xanthine oxidase with the "Cooperstown cocktail". | Q51373538 | ||
| Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation. | Q51623373 | ||
| Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients. | Q51623376 | ||
| Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily. | Q51635996 | ||
| Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4. | Q51751197 | ||
| Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein. | Q52534774 | ||
| Cytochrome P450 3A proteins are expressed in B lymphocytes but not in T lymphocytes | Q62514003 | ||
| CYP 3A proteins are expressed in human neutrophils and lymphocytes but are not induced by rifampicin | Q62514009 | ||
| A simple useful method for the determination of hepatic function in patients with liver cirrhosis using caffeine and its three major dimethylmetabolites | Q67925094 | ||
| Computation of model-independent pharmacokinetic parameters during multiple dosing | Q71044769 | ||
| CYP2D6 mRNA expression in circulating peripheral blood mononuclear cells correlates with in vivo debrisoquine hydroxylase activity in extensive metabolizers | Q71595330 | ||
| Improved high-performance liquid chromatographic determination of debrisoquine and 4-hydroxydebrisoquine in human urine following direct injection | Q71791319 | ||
| The hydroxylation of omeprazole correlates with S-mephenytoin metabolism: a population study | Q72313200 | ||
| CYP1A1 mRNA levels as a human exposure biomarker: use of quantitative polymerase chain reaction to measure CYP1A1 expression in human peripheral blood lymphocytes | Q72560453 | ||
| In vivo modulation of CYP enzymes by quinidine and rifampin | Q73148564 | ||
| Pharmacogenetic determinants of codeine induction by rifampin: the impact on codeine's respiratory, psychomotor and miotic effects | Q73224841 | ||
| Validation of the five-drug "Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolizing enzymes | Q73846452 | ||
| Expression of xenobiotic-metabolizing cytochrome P450s in human pulmonary tissues | Q74089731 | ||
| Intra-individual variation and sex differences in gene expression of cytochromes P450 in circulating leukocytes | Q74242161 | ||
| Quantitative RT-PCR for CYP3A4 mRNA in human peripheral lymphocytes: induction of CYP3A4 in lymphocytes and in liver by rifampicin | Q74278977 | ||
| Independent patterns of cytochrome P450 gene expression in liver and blood in patients with suspected liver disease | Q74617440 | ||
| Induction of hepatic mrp2 (cmrp/cmoat) gene expression in nonhuman primates treated with rifampicin or tamoxifen | Q78018225 | ||
| Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver | Q78171955 | ||
| P433 | issue | 8 | |
| P304 | page(s) | 583-593 | |
| P577 | publication date | 2005-07-22 | |
| P1433 | published in | European Journal of Clinical Pharmacology | Q1376707 |
| P1476 | title | Cytochrome P450 mRNA expression in peripheral blood lymphocytes as a predictor of enzyme induction | |
| P478 | volume | 61 |
| Q53077446 | Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries. |
| Q36851598 | Effects of in vitro brevetoxin exposure on apoptosis and cellular metabolism in a leukemic T cell line (Jurkat) |
| Q50063390 | Evidence for cytochrome P450 2B1/2B2 isoenzymes in freshly prepared peripheral blood lymphocytes |
| Q45795398 | Human T lymphocytes bioactivate heterocyclic aromatic amines by forming DNA adducts. |
| Q38634986 | Impact of physiological, pathological and environmental factors on the expression and activity of human cytochrome P450 2D6 and implications in precision medicine |
| Q38132218 | In vitro drug metabolism testing using blood-monocyte derivatives. |
| Q37310533 | Inflammation and Immune Regulation as Potential Drug Targets in Antidepressant Treatment. |
| Q58586562 | Plasma extracellular nanovesicle (exosome) derived biomarkers for drug metabolism pathways: A novel approach to characterise variability in drug exposure |
| Q51812810 | Similarities in diesel exhaust particles induced alterations in expression of cytochrome P-450 and glutathione S-transferases in rat lymphocytes and lungs. |
| Q37230649 | The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC. |
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