Role of the Pseudomonas aeruginosa oxyR-recG operon in oxidative stress defense and DNA repair: OxyR-dependent regulation of katB-ankB, ahpB, and ahpC-ahpF

scientific journal article

Role of the Pseudomonas aeruginosa oxyR-recG operon in oxidative stress defense and DNA repair: OxyR-dependent regulation of katB-ankB, ahpB, and ahpC-ahpF is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JB.182.16.4533-4544.2000
P3181OpenCitations bibliographic resource ID3002877
P932PMC publication ID94625
P698PubMed publication ID10913087
P5875ResearchGate publication ID12406905

P2093author name stringM. L. Vasil
D. J. Hassett
E. Alsabbagh
K. Parvatiyar
U. A. Ochsner
P2860cites workCloning and characterization of the Pseudomonas aeruginosa sodA and sodB genes encoding manganese- and iron-cofactored superoxide dismutase: demonstration of increased manganese superoxide dismutase activity in alginate-producing bacteriaQ24681687
Role of oxidants in microbial pathophysiologyQ24683780
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectorsQ26778475
Thioredoxin-dependent hydroperoxide peroxidase activity of bacterioferritin comigratory protein (BCP) as a new member of the thiol-specific antioxidant protein (TSA)/Alkyl hydroperoxide peroxidase C (AhpC) familyQ28369099
Mycobacterium tuberculosis KatG is a peroxynitritaseQ28487586
Bacterioferritin A modulates catalase A (KatA) activity and resistance to hydrogen peroxide in Pseudomonas aeruginosaQ28492800
Ferric uptake regulator mutants of Pseudomonas aeruginosa with distinct alterations in the iron-dependent repression of exotoxin A and siderophores in aerobic and microaerobic environmentsQ28493020
Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: cycle selection of iron-regulated genesQ29346768
A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutantsQ29547327
The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosisQ29615201
A rapid boiling method for the preparation of bacterial plasmidsQ29615281
Construction of improved Escherichia-Pseudomonas shuttle vectors derived from pUC18/19 and sequence of the region required for their replication in Pseudomonas aeruginosaQ29615291
Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxideQ33179293
A protease-resistant catalase, KatA, released upon cell lysis during stationary phase is essential for aerobic survival of a Pseudomonas aeruginosa oxyR mutant at low cell densitiesQ33180763
Ambidextrous transcriptional activation by SoxS: requirement for the C-terminal domain of the RNA polymerase alpha subunit in a subset of Escherichia coli superoxide-inducible genesQ48067417
Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene: implications for sensitivity to isoniazidQ48070782
An improved system for gene replacement and xylE fusion analysis in Pseudomonas aeruginosaQ48073553
Flavin-dependent alkyl hydroperoxide reductase from Salmonella typhimurium. 1. Purification and enzymatic activities of overexpressed AhpF and AhpC proteinsQ50140552
Thiol-mediated disassembly and reassembly of [2Fe-2S] clusters in the redox-regulated transcription factor SoxR.Q52533076
Evidence for regulation of the NADH peroxidase gene (npr) from Enterococcus faecalis by OxyR.Q54563994
Induction of repair capacity for oxidatively damaged DNA as a component of peroxide stress response in Escherichia coli.Q54581281
Superoxide DismutasesQ67916227
A double staining method for differentiating between two classes of mycobacterial catalase in polyacrylamide electrophoresis gelsQ68975806
OxyR and SoxRS regulation of furQ33635537
Effects of peroxides on susceptibilities of Escherichia coli and Mycobacterium smegmatis to isoniazidQ33757053
OxyR, a positive regulator of hydrogen peroxide-inducible genes in Escherichia coli and Salmonella typhimurium, is homologous to a family of bacterial regulatory proteinsQ33855733
Protective role of catalase in Pseudomonas aeruginosa biofilm resistance to hydrogen peroxide.Q33985805
Pseudomonas aeruginosa fur overlaps with a gene encoding a novel outer membrane lipoprotein, OmlA.Q33991233
Role for the oxyS gene in regulation of intracellular hydrogen peroxide in Escherichia coliQ33992377
AnkB, a periplasmic ankyrin-like protein in Pseudomonas aeruginosa, is required for optimal catalase B (KatB) activity and resistance to hydrogen peroxideQ33994508
DNA damage and oxygen radical toxicityQ34172435
Transcriptional regulator of oxidative stress-inducible genes: direct activation by oxidationQ34207376
Activation of the OxyR transcription factor by reversible disulfide bond formationQ34459806
Lack of expression of the global regulator OxyR in Haemophilus influenzae has a profound effect on growth phenotypeQ35528945
Pseudomonas aeruginosa sodA and sodB mutants defective in manganese- and iron-cofactored superoxide dismutase activity demonstrate the importance of the iron-cofactored form in aerobic metabolismQ35598025
Cloning and characterization of the katB gene of Pseudomonas aeruginosa encoding a hydrogen peroxide-inducible catalase: purification of KatB, cellular localization, and demonstration that it is essential for optimal resistance to hydrogen peroxideQ35598618
Mutation of the Bacillus subtilis alkyl hydroperoxide reductase (ahpCF) operon reveals compensatory interactions among hydrogen peroxide stress genesQ35616960
OxyR: a regulator of antioxidant genesQ35899412
Two divergently transcribed genes, soxR and soxS, control a superoxide response regulon of Escherichia coliQ36145766
An alkyl hydroperoxide reductase induced by oxidative stress in Salmonella typhimurium and Escherichia coli: genetic characterization and cloning of ahpQ36175734
Mutagenesis and stress responses induced in Escherichia coli by hydrogen peroxideQ36239906
Molecular basis for the exquisite sensitivity of Mycobacterium tuberculosis to isoniazidQ36689948
Genetics of PseudomonasQ37198130
Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol-disulfide statusQ37199804
SoxR, a [2Fe-2S] transcription factor, is active only in its oxidized formQ37325777
The OxyR regulonQ38008324
Redox-dependent shift of OxyR-DNA contacts along an extended DNA-binding site: a mechanism for differential promoter selectionQ38304435
SoxS, an activator of superoxide stress genes in Escherichia coli. Purification and interaction with DNA.Q38306247
Bacterial adaptation to oxidative stress: implications for pathogenesis and interaction with phagocytic cellsQ38308873
RecG helicase activity at three- and four-strand DNA structures.Q39728517
Analysis of the oxyR-ahpC region in isoniazid-resistant and -susceptible Mycobacterium tuberculosis complex organisms recovered from diseased humans and animals in diverse localitiesQ39783805
Protection of DNA during oxidative stress by the nonspecific DNA-binding protein Dps.Q39846834
Genetic analysis of the recG locus of Escherichia coli K-12 and of its role in recombination and DNA repairQ39938960
Pseudomonas aeruginosa biofilm sensitivity to biocides: use of hydrogen peroxide as model antimicrobial agent for examining resistance mechanisms.Q40791145
Purification and Characterization of the Mycobacterium smegmatis Catalase-Peroxidase Involved in Isoniazid ActivationQ42277904
The nucleotide sequence of recG, the distal spo operon gene in Escherichia coli K-12.Q42609213
Improved broad-host-range lac-based plasmid vectors for the isolation and characterization of protein fusions in Pseudomonas aeruginosaQ42624041
Multidegenerate DNA recognition by the OxyR transcriptional regulatorQ46065451
A small, stable RNA induced by oxidative stress: role as a pleiotropic regulator and antimutatorQ48047346
Compensatory ahpC gene expression in isoniazid-resistant Mycobacterium tuberculosis.Q48063219
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectPseudomonas aeruginosaQ31856
oxidative stressQ898814
P304page(s)4533–4544
P577publication date2000-08-01
P1433published inJournal of BacteriologyQ478419
P1476titleRole of the Pseudomonas aeruginosa oxyR-recG operon in oxidative stress defense and DNA repair: OxyR-dependent regulation of katB-ankB, ahpB, and ahpC-ahpF
P478volume182

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cites work (P2860)
Q93052383A LysR-Type Transcriptional Regulator LcrX Is Involved in Virulence, Biofilm Formation, Swimming Motility, Siderophore Secretion, and Growth in Sugar Sources in Xanthomonas axonopodis Pv. glycines
Q40509995A comparison of the effects of ocular preservatives on mammalian and microbial ATP and glutathione levels
Q35097157A long-chain flavodoxin protects Pseudomonas aeruginosa from oxidative stress and host bacterial clearance
Q28492831A non-classical LysR-type transcriptional regulator PA2206 is required for an effective oxidative stress response in Pseudomonas aeruginosa
Q57468600A novel subfamily of bacterial AAT-fold basic amino acid decarboxylases and functional characterization of its first representative: Pseudomonas aeruginosa LdcA
Q33180763A protease-resistant catalase, KatA, released upon cell lysis during stationary phase is essential for aerobic survival of a Pseudomonas aeruginosa oxyR mutant at low cell densities
Q51489925A trade-off between oxidative stress resistance and DNA repair plays a role in the evolution of elevated mutation rates in bacteria.
Q28492600ATP-dependent RecG helicase is required for the transcriptional regulator OxyR function in Pseudomonas species
Q34933370Adaptation genomics of a small-colony variant in a Pseudomonas chlororaphis 30-84 biofilm.
Q46605705Ag nanoparticles generated using bio-reduction and -coating cause microbial killing without cell lysis
Q36236527Agrobacterium tumefaciens estC, Encoding an Enzyme Containing Esterase Activity, Is Regulated by EstR, a Regulator in the MarR Family.
Q33997228Alkyl hydroperoxide reductase is the primary scavenger of endogenous hydrogen peroxide in Escherichia coli
Q91941162An approach to the photocatalytic mechanism in the TiO2-nanomaterials microorganism interface for the control of infectious processes
Q30441205An ortholog of OxyR in Legionella pneumophila is expressed postexponentially and negatively regulates the alkyl hydroperoxide reductase (ahpC2D) operon
Q28493116Analyses of the regulatory mechanism and physiological roles of Pseudomonas aeruginosa OhrR, a transcription regulator and a sensor of organic hydroperoxides
Q33269165Analysis of environmental transcriptomes by DNA microarrays.
Q33988075Analyzing cell physiology in C. elegans with fluorescent ratiometric reporters.
Q33994508AnkB, a periplasmic ankyrin-like protein in Pseudomonas aeruginosa, is required for optimal catalase B (KatB) activity and resistance to hydrogen peroxide
Q35685926Antibacterial Properties and Mechanism of Activity of a Novel Silver-Stabilized Hydrogen Peroxide
Q34009631Antioxidant enzyme expression in clinical isolates of Pseudomonas aeruginosa: identification of an atypical form of manganese superoxide dismutase
Q36304230Bacillus aryabhattai SRB02 tolerates oxidative and nitrosative stress and promotes the growth of soybean by modulating the production of phytohormones.
Q91548810Both silver ions and silver nanoparticles facilitate the horizontal transfer of plasmid-mediated antibiotic resistance genes
Q40069067Can microbial cells develop resistance to oxidative stress in antimicrobial photodynamic inactivation?
Q33950746Characterization of glutathione amide reductase from Chromatium gracile. Identification of a novel thiol peroxidase (Prx/Grx) fueled by glutathione amide redox cycling
Q36162728Characterization of the Neisseria meningitidis Helicase RecG.
Q38307133Characterization of the OxyR regulon of Neisseria gonorrhoeae
Q41222156Comparative Genomics of Bacillus amyloliquefaciens Strains Reveals a Core Genome with Traits for Habitat Adaptation and a Secondary Metabolites Rich Accessory Genome.
Q33788373Comparative analysis of differentially expressed genes in Shewanella oneidensis MR-1 following exposure to UVC, UVB, and UVA radiation
Q30393835Comparative genomic analysis of four representative plant growth-promoting rhizobacteria in Pseudomonas
Q45351024Cupriavidus pinatubonensis AEO106 deals with copper-induced oxidative stress before engaging in biodegradation of the herbicide 4-chloro-2-methylphenoxyacetic acid
Q35185082Cytotoxicity of Pseudomonas secreted exotoxins requires OxyR expression
Q47760451Differential roles of OxyR-controlled antioxidant enzymes alkyl hydroperoxide reductase (AhpCF) and catalase (KatB) in the protection of Pseudomonas aeruginosa against hydrogen peroxide in biofilm vs. planktonic culture.
Q34527492DsbM, a novel disulfide oxidoreductase affects aminoglycoside resistance in Pseudomonas aeruginosa by OxyR-regulated response
Q37188538Enhancement of the Chaperone Activity of Alkyl Hydroperoxide Reductase C from Pseudomonas aeruginosa PAO1 Resulting from a Point-Specific Mutation Confers Heat Tolerance in Escherichia coli
Q35084943Essential O2-responsive genes of Pseudomonas aeruginosa and their network revealed by integrating dynamic data from inverted conditions
Q37291373Evidence for Direct Control of Virulence and Defense Gene Circuits by the Pseudomonas aeruginosa Quorum Sensing Regulator, MvfR
Q44639518Flavodoxin overexpression confers tolerance to oxidative stress in beneficial soil bacteria and improves survival in the presence of the herbicides paraquat and atrazine.
Q28492703Gene expression and physiological role of Pseudomonas aeruginosa methionine sulfoxide reductases during oxidative stress
Q30500183Gene expression in Pseudomonas aeruginosa swarming motility.
Q28492754GeneChip expression analysis of the iron starvation response in Pseudomonas aeruginosa: identification of novel pyoverdine biosynthesis genes
Q33995410Genetic and physiological characterization of ohr, encoding a protein involved in organic hydroperoxide resistance in Pseudomonas aeruginosa
Q42710679Genome-wide transcriptional profiling of the steady-state response of Pseudomonas aeruginosa to hydrogen peroxide
Q64108075Genomic and transcriptomic characterization of Pseudomonas aeruginosa small colony variants derived from a chronic infection model
Q30789879Global analysis of cellular factors and responses involved in Pseudomonas aeruginosa resistance to arsenite
Q29346771Global regulation of gene expression by OxyR in an important human opportunistic pathogen
Q39886993Glutathione and catalase provide overlapping defenses for protection against respiration-generated hydrogen peroxide in Haemophilus influenzae
Q33180982Hydrogen peroxide sensitivity of catechol-2,3-dioxygenase: a cautionary note on use of xylE reporter fusions under aerobic conditions
Q24561961Identification of tandem duplicate regulatory small RNAs in Pseudomonas aeruginosa involved in iron homeostasis
Q36709442Insights into the Function of a Second, Nonclassical Ahp Peroxidase, AhpA, in Oxidative Stress Resistance in Bacillus subtilis
Q44618095Involvement of nitric oxide synthase in sucrose-enhanced hydrogen peroxide tolerance of Rhodococcus sp. strain APG1, a plant-colonizing bacterium
Q42065789KatA, the major catalase, is critical for osmoprotection and virulence in Pseudomonas aeruginosa PA14
Q34018936Macrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence.
Q37507633Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruginosa.
Q24816990Microarray analysis of Pseudomonas aeruginosa reveals induction of pyocin genes in response to hydrogen peroxide
Q91964035Molecular Mechanisms That Define Redox Balance Function in Pathogen-Host Interactions-Is There a Role for Dietary Bioactive Polyphenols?
Q35753078Molecular mechanism involved in the response to hydrogen peroxide stress in Acinetobacter oleivorans DR1.
Q36524017Mycobacterium tuberculosis RecG binds and unwinds model DNA substrates with a preference for Holliday junctions
Q38628882Necessity of OxyR for the hydrogen peroxide stress response and full virulence in Ralstonia solanacearum
Q44286549Organic hydroperoxide resistance gene encodes a thiol-dependent peroxidase
Q38222588Oxidative stress response in Pseudomonas putida
Q34526080OxyR acts as a repressor of catalase expression in Neisseria gonorrhoeae
Q29346845OxyR regulated the expression of two major catalases, KatA and KatB, along with peroxiredoxin, AhpC in Pseudomonas putida
Q57294459OxyR regulates the transcriptional response to hydrogen peroxide
Q36281008Peroxide-sensing transcriptional regulators in bacteria
Q89555169Phenotypic Adaption of Pseudomonas aeruginosa by Hacking Siderophores Produced by Other Microorganisms
Q44710680Physiological characterization of Haemophilus influenzae Rd deficient in its glutathione-dependent peroxidase PGdx
Q89863579Protection from hydrogen peroxide stress relies mainly on AhpCF and KatA2 in Stenotrophomonas maltophilia
Q28492782Proteomic, microarray, and signature-tagged mutagenesis analyses of anaerobic Pseudomonas aeruginosa at pH 6.5, likely representing chronic, late-stage cystic fibrosis airway conditions
Q28492540Proteomics of the oxidative stress response induced by hydrogen peroxide and paraquat reveals a novel AhpC-like protein in Pseudomonas aeruginosa
Q37503911Pseudomonas aeruginosa Enolase Influences Bacterial Tolerance to Oxidative Stresses and Virulence
Q35730258Pseudomonas aeruginosa IscR-Regulated Ferredoxin NADP(+) Reductase Gene (fprB) Functions in Iron-Sulfur Cluster Biogenesis and Multiple Stress Response.
Q28492555Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection
Q33769361Pseudomonas aeruginosa OxyR is required for full virulence in rodent and insect models of infection and for resistance to human neutrophils
Q42727261Pseudomonas aeruginosa SoxR does not conform to the archetypal paradigm for SoxR-dependent regulation of the bacterial oxidative stress adaptive response
Q28493125Pseudomonas aeruginosa thiol peroxidase protects against hydrogen peroxide toxicity and displays atypical patterns of gene regulation
Q58795976Pseudomonas aeruginosa ttcA encoding tRNA-thiolating protein requires an iron-sulfur cluster to participate in hydrogen peroxide-mediated stress protection and pathogenicity
Q36197469Pseudomonas syringae Catalases Are Collectively Required for Plant Pathogenesis
Q52597647PutA Is Required for Virulence and Regulated by PruR in Pseudomonas aeruginosa.
Q53742439Reactive oxygen species-scavenging system is involved in l-amino acid oxidase accumulation in Pseudoalteromonas sp. B3.
Q41130816Regulation of Organic Hydroperoxide Stress Response by Two OhrR Homologs in Pseudomonas aeruginosa
Q29346525Regulation of catalase-peroxidase KatG is OxyR dependent and Fur independent in Caulobacter crescentus
Q41962046Regulation of hydrogen peroxide-dependent gene expression in Rhodobacter sphaeroides: regulatory functions of OxyR.
Q38690012Reorganization of gene network for degradation of polycyclic aromatic hydrocarbons (PAHs) in Pseudomonas aeruginosa PAO1 under several conditions
Q44333758Rhamnolipid production: effect of oxidative stress on virulence factors and proteome of Pseudomonas aeruginosa PA1.
Q41911365RpoS expression and the general stress response in Azotobacter vinelandii during carbon and nitrogen diauxic shifts
Q50043378Salmonella detoxifying enzymes are sufficient to cope with the host oxidative burst
Q39019319The Antibacterial Effects of an Antimicrobial Peptide Human β-Defensin 3 Fused with Carbohydrate-Binding Domain on Pseudomonas aeruginosa PA14.
Q48278135The Burkholderia pseudomallei oxyR gene: expression analysis and mutant characterization
Q27673424The Oxidation-sensing Regulator (MosR) Is a New Redox-dependent Transcription Factor in Mycobacterium tuberculosis
Q47152963The OxyR-regulated phnW gene encoding 2-aminoethylphosphonate:pyruvate aminotransferase helps protect Pseudomonas aeruginosa from tert-butyl hydroperoxide
Q33553523The katA catalase gene is regulated by OxyR in both free-living and symbiotic Sinorhizobium meliloti
Q28492604The major catalase gene (katA) of Pseudomonas aeruginosa PA14 is under both positive and negative control of the global transactivator OxyR in response to hydrogen peroxide
Q73296897The oxyR from Agrobacterium tumefaciens: evaluation of its role in the regulation of catalase and peroxide responses
Q33321823The peptidoglycan-associated lipoprotein OprL helps protect a Pseudomonas aeruginosa mutant devoid of the transactivator OxyR from hydrogen peroxide-mediated killing during planktonic and biofilm culture
Q37232768The quorum sensing-dependent gene katG of Burkholderia glumae is important for protection from visible light
Q43060198The rhodanese RhdA helps Azotobacter vinelandii in maintaining cellular redox balance
Q39798896The stringent response controls catalases in Pseudomonas aeruginosa and is required for hydrogen peroxide and antibiotic tolerance
Q57039984Transcriptional recording by CRISPR spacer acquisition from RNA
Q36432014Transcriptional response of mucoid Pseudomonas aeruginosa to human respiratory mucus
Q44100060Transcriptional tradeoff between metabolic and stress-response programs in Pseudomonas putida KT2440 cells exposed to toluene
Q40377337Transcriptome analysis of the response of Pseudomonas aeruginosa to hydrogen peroxide
Q92717031TrmB, a tRNA m7G46 methyltransferase, plays a role in hydrogen peroxide resistance and positively modulates the translation of katA and katB mRNAs in Pseudomonas aeruginosa
Q35682355Unraveling the Mechanism for the Viability Deficiency of Shewanella oneidensis oxyR Null Mutant.
Q35232923Whole genome sequencing and analysis of plant growth promoting bacteria isolated from the rhizosphere of plantation crops coconut, cocoa and arecanut
Q35849996Whole-Genome Sequencing of Three Clonal Clinical Isolates of B. cenocepacia from a Patient with Cystic Fibrosis
Q34117284ohr, Encoding an organic hydroperoxide reductase, is an in vivo-induced gene in Actinobacillus pleuropneumoniae

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