FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate

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FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0092-8674(00)81437-3
P3181OpenCitations bibliographic resource ID1807428
P698PubMed publication ID9630220

P50authorWeilan YeQ64667962
P2093author name stringA Rosenthal
J L Rubenstein
K Shimamura
M A Hynes
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P433issue5
P407language of work or nameEnglishQ1860
P921main subjectdopamineQ170304
P304page(s)755-766
P577publication date1998-05-01
P1433published inCellQ655814
P1476titleFGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate
P478volume93

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Q46941800Ongoing sonic hedgehog signaling is required for dorsal midline formation in the developing forebrain
Q37735795Ontogeny of substantia nigra dopamine neurons.
Q46562616Ontogeny of tyrosine hydroxylase mRNA expression in mid- and forebrain: neuromeric pattern and novel positive regions.
Q39838576Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells.
Q28506963Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain
Q37838914Otx genes in neurogenesis of mesencephalic dopaminergic neurons
Q28550104Otx2 Requires Lmx1b to Control the Development of Mesodiencephalic Dopaminergic Neurons
Q48515364Otx2 controls identity and fate of glutamatergic progenitors of the thalamus by repressing GABAergic differentiation.
Q24297619Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation
Q36549267Oxygen Tension Within the Neurogenic Niche Regulates Dopaminergic Neurogenesis in the Developing Midbrain
Q38057859Parkinson's disease: from genetics to treatments
Q22337080Peptidergic agonists of activity-dependent neurotrophic factor protect against prenatal alcohol-induced neural tube defects and serotonin neuron loss
Q34118080Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease
Q34172684Pet-1 ETS gene plays a critical role in 5-HT neuron development and is required for normal anxiety-like and aggressive behavior.
Q37735797Phenotype, compartmental organization and differential vulnerability of nigral dopaminergic neurons.
Q38295627Phenotypic differentiation during migration of dopaminergic progenitor cells to the olfactory bulb.
Q28594955Pitx3 activates mouse tyrosine hydroxylase promoter via a high-affinity binding site
Q44408466Pitx3 is required for motor activity and for survival of a subset of midbrain dopaminergic neurons
Q28588138Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development
Q77891971Plasticity and stem cells in the vertebrate nervous system
Q37269000Pleiotropic function of FGF-4: its role in development and stem cells
Q36804572Potential application of embryonic stem cells in Parkinson's disease: drug screening and cell therapy
Q43542067Prenatal alcohol exposure retards the migration and development of serotonin neurons in fetal C57BL mice
Q50550801Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain.
Q48895003Prolonged membrane depolarization enhances midbrain dopamine neuron differentiation via epigenetic histone modifications.
Q28138668Prospects for new restorative and neuroprotective treatments in Parkinson's disease
Q50454566Reducing glypican-4 in ES cells improves recovery in a rat model of Parkinson's disease by increasing the production of dopaminergic neurons and decreasing teratoma formation.
Q64943344Reelin controls the positioning of brainstem serotonergic raphe neurons.
Q24314633Regionally specified human neural progenitor cells derived from the mesencephalon and forebrain undergo increased neurogenesis following overexpression of ASCL1
Q34121992Regionally-specified second trimester fetal neural stem cells reveals differential neurogenic programming
Q32061713Regulation of retinal ganglion cell production by Sonic hedgehog.
Q38619768Regulation of the development of tectal neurons and their projections by transcription factors Brn3a and Pax7.
Q40833719Regulation of the tyrosine hydroxylase and dopamine beta-hydroxylase genes by the transcription factor AP-2.
Q47701725Regulatory analysis of the mouse Fgf3 gene: control of embryonic expression patterns and dependence upon sonic hedgehog (Shh) signalling
Q92481835Replacing what's lost: a new era of stem cell therapy for Parkinson's disease
Q39976608Repression of Fgf signaling by sprouty1-2 regulates cortical patterning in two distinct regions and times
Q36860046Retinoid acid specifies neuronal identity through graded expression of Ascl1.
Q39897306Role of Nurr1 and Ret in inducing rat embryonic neural precursors to dopaminergic neurons
Q49135878Role of Nurr1 in the Generation and Differentiation of Dopaminergic Neurons from Stem Cells.
Q57771862Role of Otx transcription factors in brain development
Q44427111SHH and FGF8 play distinct roles during development of noradrenergic neurons in the locus coeruleus of the zebrafish
Q34109406Selection Based on FOXA2 Expression Is Not Sufficient to Enrich for Dopamine Neurons From Human Pluripotent Stem Cells
Q37037504Selection of embryonic stem cell-derived enhanced green fluorescent protein-positive dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene expression in immature cell populations
Q30304529Serotonergic neurons transiently require a midline-derived FGF signal
Q28754770Shared developmental mechanisms pattern the vertebrate gill arch and paired fin skeletons
Q35865749Shh signaling guides spatial pathfinding of raphespinal tract axons by multidirectional repulsion
Q36366889Signaling by bone morphogenetic proteins directs formation of an ectodermal signaling center that regulates craniofacial development.
Q40796007Signals from the ventral midline and isthmus regulate the development of Brn3.0-expressing neurons in the midbrain
Q33889250Sim1 is a novel regulator in the differentiation of mouse dorsal raphe serotonergic neurons
Q28594387Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node
Q40644925Sonic hedgehog and FGF8 collaborate to induce dopaminergic phenotypes in the Nurr1-overexpressing neural stem cell
Q40799364Sonic hedgehog facilitates dopamine differentiation in the presence of a mesencephalic glial cell line.
Q28572747Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
Q35485792Sorting the wheat from the chaff in dopamine neuron-based cell therapies.
Q34460286Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity
Q36672240Specification and differentiation of serotonergic neurons
Q34718055Specification of catecholaminergic and serotonergic neurons.
Q33540125Specification of dopaminergic and serotonergic neurons in the vertebrate CNS.
Q47136847Specification of murine ground state pluripotent stem cells to regional neuronal populations.
Q41650135Specification of neurotransmitter identity by Phox2 proteins in neural crest stem cells
Q45297477Stem and progenitor cell-based therapy of the human central nervous system.
Q36729785Stem cell myths
Q90175398Stem cell therapy for Parkinson's disease: safety and modeling
Q37041593Stem cells expanded from the human embryonic hindbrain stably retain regional specification and high neurogenic potency
Q37002530Stem cells in development of therapeutics for Parkinson's disease: a perspective
Q34657608Stem cells in the treatment of Parkinson's disease.
Q34649735Stem-cell-based strategies for the treatment of Parkinson's disease
Q40381244Stromal cell-derived inducing activity, Nurr1, and signaling molecules synergistically induce dopaminergic neurons from mouse embryonic stem cells.
Q26827511Subset specification of central serotonergic neurons
Q48229313Sustained interactive Wnt and FGF signaling is required to maintain isthmic identity
Q36041628Tectonic‑1 contributes to the growth and migration of prostate cancer cells in vitro
Q50658399Telencephalic neural precursor cells show transient competence to interpret the dopaminergic niche of the embryonic midbrain.
Q35813916Teleostean and mammalian forebrains contrasted: Evidence from genes to behavior
Q36922947Temporal and spatial requirements of Smoothened in ventral midbrain neuronal development
Q38536402Temporally controlled modulation of FGF/ERK signaling directs midbrain dopaminergic neural progenitor fate in mouse and human pluripotent stem cells
Q28645883The ETS domain factor Pet-1 is an early and precise marker of central serotonin neurons and interacts with a conserved element in serotonergic genes
Q102220922The Mouse Dorsal Raphe Nucleus as Understood by Temporal Fgf8 Lineage Analysis
Q39381816The Multiple Roles of FGF Signaling in the Developing Spinal Cord.
Q35584090The developmental role of serotonin: news from mouse molecular genetics
Q48566256The dopamine D2 receptor regulates the development of dopaminergic neurons via extracellular signal-regulated kinase and Nurr1 activation.
Q41970350The duration of Fgf8 isthmic organizer expression is key to patterning different tectal-isthmo-cerebellum structures
Q39928191The embryonic midbrain directs neuronal specification of embryonic stem cells at early stages of differentiation
Q28590677The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation
Q36611483The engrailed transcription factors and the mesencephalic dopaminergic neurons.
Q34299883The evolving concept of a stem cell: entity or function?
Q38200738The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed
Q51300028The neurotoxicity of DE-71: effects on neural development and impairment of serotonergic signaling in zebrafish larvae.
Q34730592The role of astroglia on the survival of dopamine neurons.
Q26801864The role of dopaminergic and serotonergic systems in neurodevelopmental disorders: a focus on epilepsy and seizure susceptibility
Q34828148The role of microRNAs in human neural stem cells, neuronal differentiation and subtype specification
Q33861795The role of transcription factor Pitx3 in dopamine neuron development and Parkinson's disease
Q35095750The roles of Hedgehogs and Fibroblast Growth Factors in eye development and retinal cell rescue.
Q48270999The serotonergic phenotype is acquired by converging genetic mechanisms within the zebrafish central nervous system
Q41710059The seven-transmembrane receptor smoothened cell-autonomously induces multiple ventral cell types
Q35161067Timing of Sonic hedgehog and Gli1 expression segregates midbrain dopamine neurons
Q38257305Transcriptional comparison of human induced and primary midbrain dopaminergic neurons
Q28588303Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis
Q44495486Transforming growth factor-beta(s) are essential for the development of midbrain dopaminergic neurons in vitro and in vivo.
Q37014769Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft.
Q61804246Treatment of Parkinson's Disease through Personalized Medicine and Induced Pluripotent Stem Cells
Q45020492Tyrosine hydroxylase induction by basic fibroblast growth factor and cyclic AMP analogs in striatal neural stem cells: role of ERK1/ERK2 mitogen-activated protein kinase and protein kinase C.
Q39085008Understanding Parkinson's Disease through the Use of Cell Reprogramming
Q34435136Variation of serotonergic gene expression: neurodevelopment and the complexity of response to psychopharmacologic drugs
Q36982676Ventral specification and perturbed boundary formation in the mouse midbrain in the absence of Hedgehog signaling
Q46829388Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish
Q35618872Vitamin C facilitates dopamine neuron differentiation in fetal midbrain through TET1- and JMJD3-dependent epigenetic control manner
Q28505281Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis
Q52323008Wnt signal activation induces midbrain specification through direct binding of the beta-catenin/TCF4 complex to the EN1 promoter in human pluripotent stem cells.
Q28118756Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway
Q28587554Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells
Q30480781Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice
Q37347197Zebrafish Hagoromo mutants up-regulate fgf8 postembryonically and develop neuroblastoma
Q34660824Zebrafish homologue irx1a is required for the differentiation of serotonergic neurons
Q44240668Zinc finger protein too few controls the development of monoaminergic neurons
Q28587845p57(Kip2) cooperates with Nurr1 in developing dopamine cells

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