scholarly article | Q13442814 |
P50 | author | Rosario Sanchez-Pernaute | Q59677277 |
Eva Hedlund | Q39697453 | ||
P2093 | author name string | Julio C Aguila | |
P2860 | cites work | The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age | Q21090191 |
Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector | Q21134939 | ||
GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons | Q24336322 | ||
Direct conversion of fibroblasts to functional neurons by defined factors | Q24641912 | ||
Direct lineage conversion of terminally differentiated hepatocytes to functional neurons | Q26269878 | ||
Wnt2 regulates progenitor proliferation in the developing ventral midbrain | Q28116566 | ||
Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway | Q28118756 | ||
Staging of brain pathology related to sporadic Parkinson's disease | Q28131702 | ||
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology | Q28131833 | ||
Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain | Q28258157 | ||
Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model | Q28344741 | ||
Otx2 regulates subtype specification and neurogenesis in the midbrain | Q28505456 | ||
Fate of mesencephalic AHD2-expressing dopamine progenitor cells in NURR1 mutant mice | Q28505883 | ||
Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a | Q28506749 | ||
Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain | Q28506963 | ||
Midbrain dopaminergic neurons: control of their cell fate by the engrailed transcription factors | Q28508561 | ||
Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors | Q28509973 | ||
Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons | Q28511306 | ||
Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons | Q28512859 | ||
Nurr1 regulates dopamine synthesis and storage in MN9D dopamine cells | Q28513096 | ||
Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo | Q28513819 | ||
FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate | Q28573016 | ||
Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, Msx1, Ngn2, and Pitx3 | Q28574309 | ||
The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain | Q28586297 | ||
Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons | Q28587011 | ||
p57(Kip2) cooperates with Nurr1 in developing dopamine cells | Q28587845 | ||
Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development | Q28588138 | ||
A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo | Q28588290 | ||
Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene | Q28590467 | ||
Fate of midbrain dopaminergic neurons controlled by the engrailed genes | Q28591344 | ||
Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells | Q28591758 | ||
Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain region | Q28592616 | ||
Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons | Q28593451 | ||
Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development | Q28593581 | ||
Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner | Q28594838 | ||
Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development | Q28595073 | ||
An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination | Q29615355 | ||
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling | Q29615601 | ||
Neuronal specification in the spinal cord: inductive signals and transcriptional codes | Q29616039 | ||
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts | Q29616184 | ||
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease | Q29619506 | ||
Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection | Q31172552 | ||
Cell therapy in Parkinson's disease | Q33212017 | ||
Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon | Q33232560 | ||
Early specification of dopaminergic phenotype during ES cell differentiation | Q33291244 | ||
Nigrostriatal alterations in bone morphogenetic protein receptor II dominant negative mice | Q36948842 | ||
Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft. | Q37014769 | ||
Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons. | Q37029659 | ||
Temporally induced Nurr1 can induce a non-neuronal dopaminergic cell type in embryonic stem cell differentiation | Q37037470 | ||
Selection of embryonic stem cell-derived enhanced green fluorescent protein-positive dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene expression in immature cell populations | Q37037504 | ||
Long-term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (cyno-1) after transplantation. | Q37125659 | ||
Review: Familial Parkinson's disease--genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease | Q37151410 | ||
Enhanced yield of neuroepithelial precursors and midbrain-like dopaminergic neurons from human embryonic stem cells using the bone morphogenic protein antagonist noggin. | Q37154197 | ||
Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells | Q37164421 | ||
Mediators of reprogramming: transcription factors and transitions through mitosis | Q37196129 | ||
Epigenetic reprogramming and induced pluripotency | Q37201452 | ||
Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease | Q37221341 | ||
Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. | Q37255219 | ||
Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease | Q37300209 | ||
Derivation of midbrain dopamine neurons from human embryonic stem cells | Q37493958 | ||
Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1) | Q37594723 | ||
Neuronal cell replacement in Parkinson's disease. | Q37599931 | ||
Selective cell death in neurodegeneration: why are some neurons spared in vulnerable regions? | Q37764485 | ||
Neural grafting in Parkinson's disease Problems and possibilities | Q37796027 | ||
Localization of monoamines in the lower brain stem. | Q51272663 | ||
miR-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells. | Q51865742 | ||
Regulation of isthmic Fgf8 signal by sprouty2. | Q52064187 | ||
Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. | Q52223119 | ||
Expression patterns of the homeo box-containing genes En-1 and En-2 and the proto-oncogene int-1 diverge during mouse development. | Q52249431 | ||
Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease. | Q53169445 | ||
Cell reprogramming gets direct | Q58951621 | ||
Parkinson's disease: an immunohistochemical study of Lewy body-containing neurons in the enteric nervous system | Q68090964 | ||
Rat liver aldehyde dehydrogenase. II. Isolation and characterization of four inducible isozymes | Q70620893 | ||
Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages | Q74378538 | ||
The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway | Q80418542 | ||
The role of Lmx1a in the differentiation of human embryonic stem cells into midbrain dopamine neurons in culture and after transplantation into a Parkinson's disease model | Q46333946 | ||
Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon | Q46344386 | ||
Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections. | Q46586692 | ||
Altered dopaminergic innervation and amphetamine response in adult Otx2 conditional mutant mice | Q46779826 | ||
Bone morphogenetic protein-7 reduces toxicity induced by high doses of methamphetamine in rodents. | Q46848145 | ||
Identification of intrinsic determinants of midbrain dopamine neurons | Q46913434 | ||
Purified mouse dopamine neurons thrive and function after transplantation into brain but require novel glial factors for survival in culture | Q46926584 | ||
Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis | Q47073664 | ||
FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate. | Q48092092 | ||
Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease. | Q48095855 | ||
Development of dopaminergic neurons in the human mesencephalon and in vitro effects of basic fibroblast growth factor treatment | Q48100983 | ||
Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency. | Q48126278 | ||
The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease | Q48147372 | ||
The substantia nigra of the human brain. I. Nigrosomes and the nigral matrix, a compartmental organization based on calbindin D(28K) immunohistochemistry | Q48147383 | ||
FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors | Q48152543 | ||
Distribution of the catecholaminergic neurons in the central nervous system of human embryos and fetuses | Q48165800 | ||
Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants. | Q48169771 | ||
Modulation of L-DOPA-induced abnormal involuntary movements by clinically tested compounds: further validation of the rat dyskinesia model | Q48270157 | ||
Acquisition of in vitro and in vivo functionality of Nurr1-induced dopamine neurons. | Q48381886 | ||
LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal. | Q48472909 | ||
The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. | Q48480210 | ||
Transforming growth factor beta is required for differentiation of mouse mesencephalic progenitors into dopaminergic neurons in vitro and in vivo: ectopic induction in dorsal mesencephalon. | Q48513133 | ||
GIRK2 expression in dopamine neurons of the substantia nigra and ventral tegmental area. | Q48709665 | ||
Fluorescence-activated cell sorting-based purification of embryonic stem cell-derived neural precursors averts tumor formation after transplantation. | Q48730923 | ||
Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. | Q48791624 | ||
A cytoarchitectonic and chemoarchitectonic analysis of the dopamine cell groups in the substantia nigra, ventral tegmental area, and retrorubral field in the mouse. | Q48887515 | ||
Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors. | Q48924532 | ||
Cell therapeutics in Parkinson's disease | Q37929026 | ||
A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b. | Q38314171 | ||
Temporally controlled modulation of FGF/ERK signaling directs midbrain dopaminergic neural progenitor fate in mouse and human pluripotent stem cells | Q38536402 | ||
Pitx3 is a critical mediator of GDNF-induced BDNF expression in nigrostriatal dopaminergic neurons. | Q39477781 | ||
Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells | Q39712582 | ||
Transcription factor-induced lineage selection of stem-cell-derived neural progenitor cells | Q39744737 | ||
Direct conversion of C. elegans germ cells into specific neuron types. | Q40146571 | ||
Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes. | Q40216832 | ||
Stromal cell-derived inducing activity, Nurr1, and signaling molecules synergistically induce dopaminergic neurons from mouse embryonic stem cells. | Q40381244 | ||
The Role of the Floor Plate in Axon Guidance | Q40441128 | ||
The homeodomain transcription factor Pitx3 facilitates differentiation of mouse embryonic stem cells into AHD2-expressing dopaminergic neurons. | Q40462051 | ||
Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation | Q40493282 | ||
TGF-beta superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP+ toxicity | Q40805796 | ||
Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. | Q40876310 | ||
Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes. | Q40942115 | ||
Bone morphogenetic proteins: neurotrophic roles for midbrain dopaminergic neurons and implications of astroglial cells | Q41096397 | ||
Diversity and pattern in the developing spinal cord | Q41191457 | ||
Expression of the homeo box-containing gene En-2 delineates a specific region of the developing mouse brain | Q41252832 | ||
Trophic and protective effects of growth/differentiation factor 5, a member of the transforming growth factor-beta superfamily, on midbrain dopaminergic neurons | Q41264189 | ||
TGF beta 2 and TGF beta 3 are potent survival factors for midbrain dopaminergic neurons | Q41431348 | ||
Involvement of androgen-induced growth factor (FGF-8) gene in mouse embryogenesis and morphogenesis | Q41434731 | ||
Efficient derivation of functional floor plate tissue from human embryonic stem cells | Q41828883 | ||
Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D28k-containing cells | Q41843416 | ||
Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons. | Q41897447 | ||
A critical evaluation of the Braak staging scheme for Parkinson's disease. | Q42260364 | ||
Buspirone in levodopa-induced dyskinesias | Q42285208 | ||
Shh dependent and independent maintenance of basal midbrain | Q42451110 | ||
Induction of dopaminergic neuron phenotype in the midbrain by Sonic hedgehog protein | Q42479348 | ||
Heterogeneous distribution of kir3 potassium channel proteins within dopaminergic neurons in the mesencephalon of the rat brain | Q42507090 | ||
Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults | Q42727069 | ||
Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP. | Q42832693 | ||
Graft-induced dyskinesias in Parkinson's disease: what is it all about? | Q42947830 | ||
Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants | Q42997555 | ||
Stem cells and cell replacement therapy for Parkinson's disease. | Q43089181 | ||
Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon | Q43207403 | ||
Genetic selection of sox1GFP-expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation | Q43218046 | ||
Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons | Q43218195 | ||
Embryonic stem cells with GFP knocked into the dopamine transporter yield purified dopamine neurons in vitro and from knock-in mice | Q43277194 | ||
Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. | Q44037381 | ||
Pitx3 is required for motor activity and for survival of a subset of midbrain dopaminergic neurons | Q44408466 | ||
Location and size of dopaminergic and serotonergic cell populations are controlled by the position of the midbrain-hindbrain organizer. | Q44451987 | ||
Selective loss of dopaminergic neurons in the substantia nigra of Pitx3-deficient aphakia mice | Q44493207 | ||
Transforming growth factor-beta(s) are essential for the development of midbrain dopaminergic neurons in vitro and in vivo. | Q44495486 | ||
Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. | Q44591596 | ||
Transgenic expression of Cre recombinase from the tyrosine hydroxylase locus | Q44598796 | ||
Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons | Q44796512 | ||
Isolation and transplantation of dopaminergic neurons generated from mouse embryonic stem cells | Q44906339 | ||
Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers | Q45039594 | ||
Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian rats | Q45173532 | ||
The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum. | Q45944197 | ||
Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis. | Q45952942 | ||
Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT1A and 5-HT1B receptor agonists in the rat Parkinson model. | Q45981005 | ||
Midbrain development induced by FGF8 in the chick embryo. | Q46013905 | ||
FGF8 signaling regulates growth of midbrain dopaminergic axons by inducing semaphorin 3F. | Q46064927 | ||
Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration | Q33387798 | ||
A novel combination of factors, termed SPIE, which promotes dopaminergic neuron differentiation from human embryonic stem cells | Q33492749 | ||
Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model. | Q33565361 | ||
Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. | Q33925878 | ||
Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity. | Q34010256 | ||
Small molecules enable highly efficient neuronal conversion of human fibroblasts | Q34031414 | ||
Foxa2 and Nurr1 synergistically yield A9 nigral dopamine neurons exhibiting improved differentiation, function, and cell survival | Q34091038 | ||
Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats | Q34115609 | ||
Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease | Q34118080 | ||
Ectopic Wnt/beta-catenin signaling induces neurogenesis in the spinal cord and hindbrain floor plate | Q34140439 | ||
Direct conversion of human fibroblasts to dopaminergic neurons | Q34190302 | ||
Dopaminergic neuronal differentiation from rat embryonic neural precursors by Nurr1 overexpression. | Q34202895 | ||
Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor | Q34280164 | ||
Fgf-8 expression in the post-gastrulation mouse suggests roles in the development of the face, limbs and central nervous system. | Q34319673 | ||
Dopaminergic neurons from embryonic mouse mesencephalon are enriched in culture through immunoreaction with monoclonal antibody to neural specific protein 4 and flow cytometry | Q34355921 | ||
Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease. | Q34416128 | ||
Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development | Q34658837 | ||
Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system | Q34761835 | ||
Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years | Q34768147 | ||
Anatomical basis of glial cell line-derived neurotrophic factor expression in the striatum and related basal ganglia during postnatal development of the rat. | Q34974241 | ||
Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors | Q35002960 | ||
ES cell-derived renewable and functional midbrain dopaminergic progenitors. | Q35034938 | ||
Neural transplantation for the treatment of Parkinson's disease | Q35172255 | ||
Functional integration of dopaminergic neurons directly converted from mouse fibroblasts | Q35534141 | ||
Vertebrate floor-plate specification: variations on common themes | Q35704419 | ||
Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells. | Q35732928 | ||
Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies. | Q35764504 | ||
Homeobox gene Pitx3 and its role in the development of dopamine neurons of the substantia nigra | Q35858546 | ||
Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons | Q35947054 | ||
Neurotrophic regulation of retinal ganglion cell synaptic connectivity: from axons and dendrites to synapses | Q35959776 | ||
Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants improve recovery after cervical spinal cord injury. | Q36243098 | ||
Markers and methods for cell sorting of human embryonic stem cell-derived neural cell populations | Q36453736 | ||
Calcium, ageing, and neuronal vulnerability in Parkinson's disease | Q36947731 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P304 | page(s) | 412040 | |
P577 | publication date | 2012-09-04 | |
P1433 | published in | Stem Cells International | Q26842114 |
P1476 | title | Cellular programming and reprogramming: sculpting cell fate for the production of dopamine neurons for cell therapy | |
P478 | volume | 2012 |
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