A role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure

scientific journal article

A role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/EMBOJ/CDG440
P932PMC publication ID202382
P698PubMed publication ID12941696
P5875ResearchGate publication ID10594617

P50authorChia-Yang LiuQ71235137
James JesterQ73065079
P2093author name stringLin Zhang
Wei Wang
David E Birk
Min Gao
Michael Karin
Ying Xia
Yasuhito Hayashi
Winston W-Y Kao
P2860cites workJNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extensionQ22007973
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Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cellsQ24534057
Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinaseQ24643910
Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1Q28114883
Signal transduction by the JNK group of MAP kinasesQ28142592
Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruptionQ28290282
c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritisQ28343409
Nuk controls pathfinding of commissural axons in the mammalian central nervous systemQ28507318
c-Jun is essential for organization of the epidermal leading edgeQ28588242
Rho GTPases control polarity, protrusion, and adhesion during cell movementQ29614244
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domainQ29620169
p115 Rho GTPase activating protein interacts with MEKK1.Q30165313
Organization of junctional proteins in proliferating cat corneal endothelium during wound healing.Q30979866
TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathwayQ33890533
MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq.Q34020904
Eyelid development, fusion and subsequent reopening in the mouse.Q34087030
Dynamic analysis of dorsal closure in Drosophila: from genetics to cell biologyQ34731335
MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activationQ35156450
Transforming growth factor-beta mediates intestinal healing and susceptibility to injury in vitro and in vivo through epithelial cellsQ35748961
Eyelid development and fusion induced by cortisone treatment in mutant, lidgap-Miller, foetal mice. A scanning electron microscope studyQ36475765
Cornea-specific expression of K12 keratin during mouse development.Q36673793
MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.Q36967719
MEK kinase 1 induces mitochondrial permeability transition leading to apoptosis independent of cytochrome c releaseQ40760800
Phorbol ester-induced expression of airway squamous cell differentiation marker, SPRR1B, is regulated by protein kinase Cdelta /Ras/MEKK1/MKK1-dependent/AP-1 signal transduction pathwayQ40864901
The regulation of AP-1 activity by mitogen-activated protein kinasesQ40998182
Hyperosmolality causes growth arrest of murine kidney cells. Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase 2.Q41037613
Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cellsQ41615795
Mediation by arachidonic acid metabolites of the H2O2-induced stimulation of mitogen-activated protein kinases (extracellular-signal-regulated kinase and c-Jun NH2-terminal kinase).Q42437341
c-Jun regulates eyelid closure and skin tumor development through EGFR signalingQ42442584
Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.Q42492769
Characterization of the mouse transforming growth factor alpha gene: its expression during eyelid development and in waved 1 tissuesQ42641677
A JNK signal transduction pathway that mediates morphogenesis and an immune response in DrosophilaQ47070626
The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain developmentQ48219557
Embryonic morphogenesis signaling pathway mediated by JNK targets the transcription factor JUN and the TGF-beta homologue decapentaplegic.Q52192257
Coupling of Jun amino-terminal kinase and Decapentaplegic signaling pathways in Drosophila morphogenesis.Q52193889
Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction.Q52218306
Optimization of murine keratinocyte culture for the production of graftable epidermal sheetsQ67557936
Migration of epithelium during phenytoin-dependent gingival overgrowth in miceQ72041103
Localization of collagen types I, III and V during tendon development. Changes in collagen types I and III are correlated with changes in fibril diameterQ73289078
Induction of angiogenesis by expression of soluble type II transforming growth factor-beta receptor in mouse hepatomaQ74215724
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectMitogen-activated protein kinase kinase kinase 1Q21985560
P304page(s)4443-4454
P577publication date2003-09-01
P1433published inThe EMBO JournalQ1278554
P1476titleA role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure
P478volume22

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cites work (P2860)
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