scholarly article | Q13442814 |
P50 | author | Chia-Yang Liu | Q71235137 |
James Jester | Q73065079 | ||
P2093 | author name string | Lin Zhang | |
Wei Wang | |||
David E Birk | |||
Min Gao | |||
Michael Karin | |||
Ying Xia | |||
Yasuhito Hayashi | |||
Winston W-Y Kao | |||
P2860 | cites work | JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension | Q22007973 |
Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2 | Q24313872 | ||
Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells | Q24534057 | ||
Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase | Q24643910 | ||
Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1 | Q28114883 | ||
Signal transduction by the JNK group of MAP kinases | Q28142592 | ||
Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption | Q28290282 | ||
c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis | Q28343409 | ||
Nuk controls pathfinding of commissural axons in the mammalian central nervous system | Q28507318 | ||
c-Jun is essential for organization of the epidermal leading edge | Q28588242 | ||
Rho GTPases control polarity, protrusion, and adhesion during cell movement | Q29614244 | ||
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain | Q29620169 | ||
p115 Rho GTPase activating protein interacts with MEKK1. | Q30165313 | ||
Organization of junctional proteins in proliferating cat corneal endothelium during wound healing. | Q30979866 | ||
TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway | Q33890533 | ||
MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq. | Q34020904 | ||
Eyelid development, fusion and subsequent reopening in the mouse. | Q34087030 | ||
Dynamic analysis of dorsal closure in Drosophila: from genetics to cell biology | Q34731335 | ||
MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation | Q35156450 | ||
Transforming growth factor-beta mediates intestinal healing and susceptibility to injury in vitro and in vivo through epithelial cells | Q35748961 | ||
Eyelid development and fusion induced by cortisone treatment in mutant, lidgap-Miller, foetal mice. A scanning electron microscope study | Q36475765 | ||
Cornea-specific expression of K12 keratin during mouse development. | Q36673793 | ||
MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration. | Q36967719 | ||
MEK kinase 1 induces mitochondrial permeability transition leading to apoptosis independent of cytochrome c release | Q40760800 | ||
Phorbol ester-induced expression of airway squamous cell differentiation marker, SPRR1B, is regulated by protein kinase Cdelta /Ras/MEKK1/MKK1-dependent/AP-1 signal transduction pathway | Q40864901 | ||
The regulation of AP-1 activity by mitogen-activated protein kinases | Q40998182 | ||
Hyperosmolality causes growth arrest of murine kidney cells. Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase 2. | Q41037613 | ||
Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells | Q41615795 | ||
Mediation by arachidonic acid metabolites of the H2O2-induced stimulation of mitogen-activated protein kinases (extracellular-signal-regulated kinase and c-Jun NH2-terminal kinase). | Q42437341 | ||
c-Jun regulates eyelid closure and skin tumor development through EGFR signaling | Q42442584 | ||
Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration. | Q42492769 | ||
Characterization of the mouse transforming growth factor alpha gene: its expression during eyelid development and in waved 1 tissues | Q42641677 | ||
A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila | Q47070626 | ||
The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development | Q48219557 | ||
Embryonic morphogenesis signaling pathway mediated by JNK targets the transcription factor JUN and the TGF-beta homologue decapentaplegic. | Q52192257 | ||
Coupling of Jun amino-terminal kinase and Decapentaplegic signaling pathways in Drosophila morphogenesis. | Q52193889 | ||
Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction. | Q52218306 | ||
Optimization of murine keratinocyte culture for the production of graftable epidermal sheets | Q67557936 | ||
Migration of epithelium during phenytoin-dependent gingival overgrowth in mice | Q72041103 | ||
Localization of collagen types I, III and V during tendon development. Changes in collagen types I and III are correlated with changes in fibril diameter | Q73289078 | ||
Induction of angiogenesis by expression of soluble type II transforming growth factor-beta receptor in mouse hepatoma | Q74215724 | ||
P433 | issue | 17 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Mitogen-activated protein kinase kinase kinase 1 | Q21985560 |
P304 | page(s) | 4443-4454 | |
P577 | publication date | 2003-09-01 | |
P1433 | published in | The EMBO Journal | Q1278554 |
P1476 | title | A role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure | |
P478 | volume | 22 |
Q28083145 | A RING to rule them all? Insights into the Map3k1 PHD motif provide a new mechanistic understanding into the diverse roles of Map3k1 |
Q30416855 | A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells. |
Q35786228 | A novel allele of Alx4 results in reduced Fgf10 expression and failure of eyelid fusion in mice |
Q34886212 | A role for the mitogen-activated protein kinase kinase kinase 1 in epithelial wound healing. |
Q36530577 | ADAM17 transactivates EGFR signaling during embryonic eyelid closure |
Q54962214 | Abrogation of transforming growth factor-β-induced tissue fibrosis in TBRIcaCol1a2Cre transgenic mice by the second generation tyrosine kinase inhibitor SKI-606 (Bosutinib). |
Q51071288 | Activin B Promotes BMSC-Mediated Cutaneous Wound Healing by Regulating Cell Migration via the JNK-ERK Signaling Pathway. |
Q34031975 | Activin B promotes epithelial wound healing in vivo through RhoA-JNK signaling pathway |
Q28610139 | Activin signaling and its role in regulation of cell proliferation, apoptosis, and carcinogenesis |
Q34046530 | Alteration of skin wound healing in keratinocyte-specific mediator complex subunit 1 null mice |
Q50941164 | Amniotic membrane stimulates cell migration by modulating transforming growth factor-β signalling. |
Q34480170 | Anthrax lethal factor and edema factor act on conserved targets in Drosophila |
Q93012770 | Calponin-3 deficiency augments contractile activity, plasticity, fibrogenic response and Yap/Taz transcriptional activation in lens epithelial cells and explants |
Q92604959 | Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development |
Q37404956 | Cell type-specific signaling function of RhoA GTPase: lessons from mouse gene targeting |
Q38270867 | Congenital upper eyelid coloboma: embryologic, nomenclatorial, nosologic, etiologic, pathogenetic, epidemiologic, clinical, and management perspectives. |
Q28590184 | Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis |
Q24302117 | Disabled-2 (Dab2) mediates transforming growth factor beta (TGFbeta)-stimulated fibronectin synthesis through TGFbeta-activated kinase 1 and activation of the JNK pathway |
Q36640551 | Ectodermal Wnt controls nasal pit morphogenesis through modulation of the BMP/FGF/JNK signaling axis. |
Q28507451 | Epithelial sheet movement requires the cooperation of c-Jun and MAP3K1 |
Q28506195 | Excess biglycan causes eyelid malformation by perturbing muscle development and TGF-alpha signaling |
Q51185489 | Exogenous FGF10 can rescue an eye-open at birth phenotype of Fgf10-null mice by activating activin and TGFalpha-EGFR signaling. |
Q37548471 | Expression of signaling components in embryonic eyelid epithelium |
Q34575826 | Eyelid closure in embryogenesis is required for ocular adnexa development |
Q37170606 | FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate |
Q35978882 | Function of Wnt/β-catenin in counteracting Tcf3 repression through the Tcf3-β-catenin interaction |
Q28641472 | Gene-Environment Interactions Target Mitogen-activated Protein 3 Kinase 1 (MAP3K1) Signaling in Eyelid Morphogenesis |
Q50199323 | Genetic background-dependent role of Egr1 for eyelid development |
Q41278303 | Grainyhead-like factor Get1/Grhl3 regulates formation of the epidermal leading edge during eyelid closure |
Q51952633 | Grhl3 and Lmo4 play coordinate roles in epidermal migration. |
Q36706331 | In vivo functions of mitogen-activated protein kinases: conclusions from knock-in and knock-out mice |
Q42927256 | Inactivation of Smad4 leads to impaired ocular development and cataract formation |
Q36305356 | Inflammation-activated protein kinases as targets for drug development |
Q57066646 | Inhibitory Antibodies against Activin A and TGF-β Reduce Self-Supported, but Not Soluble Factors-Induced Growth of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension |
Q34421669 | JNK is a novel regulator of intercellular adhesion |
Q39121816 | JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila |
Q28484233 | Keratinocyte migration in the developing eyelid requires LIMK2 |
Q37128020 | Key role for activin B in cellular transformation after loss of the von Hippel-Lindau tumor suppressor |
Q46892881 | Kinase MEKK1 is required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production |
Q30577957 | Leader cell positioning drives wound-directed collective migration in TGFβ-stimulated epithelial sheets |
Q36858825 | Loss of IκB kinase β promotes myofibroblast transformation and senescence through activation of the ROS-TGFβ autocrine loop |
Q38254321 | Loss of MAP3K1 enhances proliferation and apoptosis during retinal development |
Q30391988 | MAP3K1 function is essential for cytoarchitecture of the mouse organ of Corti and survival of auditory hair cells |
Q34853182 | MAP3Ks as central regulators of cell fate during development |
Q40270124 | MEK kinase 1 is a negative regulator of virus-specific CD8(+) T cells |
Q40729007 | MEKK1 transduces activin signals in keratinocytes to induce actin stress fiber formation and migration |
Q47129661 | MLCK-independent phosphorylation of MLC20 and its regulation by MAP kinase pathway in human bladder smooth muscle cells |
Q38604998 | Magnetic resonance imaging study of eye congenital birth defects in mouse model |
Q42596207 | Meibomian gland morphogenesis requires developmental eyelid closure and lid fusion |
Q91087958 | MicroRNAs control eyelid development through regulating Wnt signaling |
Q33894760 | Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1. |
Q35915976 | Mitogen activated protein kinases as targets for development of novel anti-inflammatory drugs |
Q35409040 | Mitogen-activated protein kinase kinase kinase 1 (MAP3K1) integrates developmental signals for eyelid closure |
Q41847267 | Mitogen-activated protein kinase kinase kinase 1 protects against nickel-induced acute lung injury. |
Q33641941 | Mixed lineage kinase-3/JNK1 axis promotes migration of human gastric cancer cells following gastrin stimulation |
Q53178607 | Molecular biology and genetics of embryonic eyelid development. |
Q37461902 | Monomeric and dimeric models of ERK2 in conjunction with studies on cellular localization, nuclear translocation, and in vitro analysis |
Q34892683 | Newly developed TGF-β2 knock down transgenic mouse lines express TGF-β2 differently and its distribution in multiple tissues varies |
Q39013667 | Non-Smad Signaling Pathways of the TGF-β Family |
Q29620040 | Non-Smad pathways in TGF-beta signaling |
Q38205111 | Nuclear and cytosolic JNK signalling in neurons |
Q36881687 | Polarity regulators and the control of epithelial architecture, cell migration, and tumorigenesis. |
Q36321444 | ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles |
Q28504557 | Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling |
Q37271710 | Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant |
Q88772826 | Repression of MAP3K1 expression and JNK activity by canonical Wnt signaling |
Q58797742 | Reversine inhibits Colon Carcinoma Cell Migration by Targeting JNK1 |
Q47740308 | Role of EGF receptor signaling on morphogenesis of eyelid and meibomian glands. |
Q35681017 | Role of JNK in mammary gland development and breast cancer |
Q28081170 | Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review) |
Q36819381 | Role of mitogen-activated protein kinase kinase kinases in signal integration |
Q28507821 | Serum response factor is essential for the proper development of skin epithelium |
Q30479005 | Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor |
Q37378046 | Spry1 and Spry2 are necessary for eyelid closure |
Q35593959 | TGF-β signaling and its role in the regulation of hematopoietic stem cells |
Q28083107 | TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis |
Q24304462 | The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines |
Q39140421 | The TGFβ-induced phosphorylation and activation of p38 mitogen-activated protein kinase is mediated by MAP3K4 and MAP3K10 but not TAK1. |
Q36663184 | The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development |
Q27300118 | The development of a novel high throughput computational tool for studying individual and collective cellular migration |
Q34551926 | The expression of Pax6 variants is subject to posttranscriptional regulation in the developing mouse eyelid |
Q36506572 | The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells. |
Q24307451 | The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity |
Q36516410 | Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer |
Q27321434 | bFGF Regulates PI3-Kinase-Rac1-JNK Pathway and Promotes Fibroblast Migration in Wound Healing |
Q37969687 | c-Jun, at the crossroad of the signaling network |
Q57794888 | mDia1 and Cdc42 regulate Activin B-induced migration of bone marrow-derived mesenchymal stromal cells |
Search more.