Inhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2

scientific journal article

Inhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.01566-08
P3181OpenCitations bibliographic resource ID2064674
P932PMC publication ID2643819
P698PubMed publication ID19103752

P2093author name stringBaolin Wang
Ming Zhao
Di Chen
Jin-Hua Liu
Jianghong Zhang
Seon-Yle Ko
Babatunde O. Oyajobi
Stephen E. Harris
Gregory R. Mundy
P2860cites workHedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limbQ22253250
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Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitroQ24675778
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Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone developmentQ28119185
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Microtubules as a target for anticancer drugsQ28253993
GLI2 mutations in four Brazilian patients: how wide is the phenotypic spectrum?Q28273397
Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and developmentQ28301976
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Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradationQ28507411
The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signalingQ28593888
Identification of a Functional Interaction between the Transmembrane Protein Smoothened and the Kinesin-Related Protein Costal2Q28634848
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblastsQ29547605
Microtubules and signal transductionQ33536499
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The ABCs of BMPsQ36050270
Structural intermediates in microtubule assembly and disassembly: how and why?Q36403866
Structural mechanisms underlying nucleotide-dependent self-assembly of tubulin and its relativesQ36426256
Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): comparison of the structures and promoter regions of BMP-2 and BMP-4 genesQ36732898
Bone morphogenetic protein 2 transcripts in rapidly developing deer antler tissue contain an extended 5' non-coding region arising from a distal promoterQ36843152
SOCS-1 localizes to the microtubule organizing complex-associated 20S proteasomeQ37527082
Comparative genomics on Sonic hedgehog orthologs.Q39123644
A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasomeQ40174315
NF-kappaB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitroQ40646195
E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast DifferentiationQ40649010
Stimulation of bone formation in vitro and in rodents by statinsQ40914337
Immortalized murine osteoblasts derived from BMP 2-T-antigen expressing transgenic miceQ41256474
Bmp2 transcription in osteoblast progenitors is regulated by a distant 3' enhancer located 156.3 kilobases from the promoterQ41975562
Transducing Hedgehog: the story so farQ42457520
Neurotoxicity of CI-980, a novel mitotic inhibitorQ42463998
KIF27 is one of orthologs for Drosophila Costal-2.Q42470639
Unique and complimentary activities of the Gli transcription factors in Hedgehog signalingQ42492714
Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and functionQ42530363
The effect of cytoskeletal disruption on pulsatile fluid flow-induced nitric oxide and prostaglandin E2 release in osteocytes and osteoblastsQ42816780
Tamoxifen and colchicine-modulated vinblastine followed by 5-fluorouracil in advanced renal cell carcinoma: a phase II studyQ43577978
Microfabricated discontinuous-edge surface topographies influence osteoblast adhesion, migration, cytoskeletal organization, and proliferation and enhance matrix and mineral deposition in vitroQ46282055
Expression of bone morphogenetic protein messenger RNA in prolonged cultures of fetal rat calvarial cellsQ46295543
Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.Q46727624
Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patientsQ46954545
Identification of a tetrameric hedgehog signaling complexQ47071804
Immunohistochemical localization of bone morphogenetic proteins and the receptors in epiphyseal growth plateQ47689524
Effect of aging on bone formation induced by recombinant human bone morphogenetic protein-2 combined with fibrous collagen membranes at subperiosteal sitesQ49189658
Accelerating lumbar fusions by combining rhBMP-2 with allograft bone: a prospective analysis of interbody fusion rates and clinical outcomes.Q51011526
Impaired endochondral bone development and osteopenia in Gli2-deficient mice.Q51022793
Autoregulation of mouse BMP-2 gene transcription is directed by the proximal promoter element.Q51064172
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing.Q52002102
The pharmacokinetics and safety of ABT-751, a novel, orally bioavailable sulfonamide antimitotic agent: results of a phase 1 study.Q52933092
Gene expression in older rats with delayed union of femoral fractures.Q54765249
The effects of aging on the bone inductive activity of recombinant human bone morphogenetic protein-2Q71733303
Inhibition of microtubule assembly in vitro by TN-16, a synthetic antitumor drugQ71737691
Immunolocalization of bone morphogenetic protein and its receptors in degeneration of intervertebral discQ78051359
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmicrotubuleQ189933
morphogenesisQ815547
osteoblastQ917177
GLI-Kruppel family member GLI2Q14886550
Bone morphogenetic protein 2Q14903156
SMAD family member 1Q14903821
SMAD family member 5Q14904355
SMAD family member 9Q14904387
Beta-transducin repeat containing proteinQ21495664
Tubulin, alpha 1AQ21498255
Tubulin, alpha 1BQ21989624
Tubulin, alpha 1CQ21989629
P304page(s)1291–1305
P577publication date2009-03-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleInhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2
P478volume29

Reverse relations

cites work (P2860)
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