| scholarly article | Q13442814 |
| P2093 | author name string | Randall S. Johnson | |
| M. Celeste Simon | |||
| Brian Keith | |||
| Cheng-Jun Hu | |||
| Michaela Gruber | |||
| Eric J. Brown | |||
| P2860 | cites work | HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing | Q24291102 |
| HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity | Q24302129 | ||
| Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension | Q24307473 | ||
| Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells | Q24314526 | ||
| HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation | Q24555773 | ||
| The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development | Q24595910 | ||
| Generalized lacZ expression with the ROSA26 Cre reporter strain | Q27860837 | ||
| Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation | Q27860876 | ||
| Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1 | Q28141355 | ||
| Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha | Q28259513 | ||
| Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice | Q28508637 | ||
| HIF-1 alpha is required for solid tumor formation and embryonic vascularization. | Q28588778 | ||
| HIF-2alpha regulates murine hematopoietic development in an erythropoietin-dependent manner | Q28589605 | ||
| The HIF family member EPAS1/HIF-2α is required for normal hematopoiesis in mice | Q28591832 | ||
| The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling | Q28592049 | ||
| Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development | Q28593302 | ||
| Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice | Q28594703 | ||
| Purification and characterization of hypoxia-inducible factor 1 | Q28678375 | ||
| Efficient in vivo manipulation of mouse genomic sequences at the zygote stage | Q29547306 | ||
| Oxygen sensing by HIF hydroxylases | Q29617806 | ||
| Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation | Q29619687 | ||
| Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor | Q33556391 | ||
| Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells. | Q33558752 | ||
| Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology | Q34343405 | ||
| HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. | Q34471121 | ||
| HIF-dependent hematopoietic factors regulate the development of the embryonic vasculature | Q35133209 | ||
| Multilineage embryonic hematopoiesis requires hypoxic ARNT activity | Q35207418 | ||
| Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses | Q35209175 | ||
| Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains | Q38343320 | ||
| Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys | Q40721597 | ||
| Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth. | Q40861131 | ||
| The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease | Q42399153 | ||
| HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia | Q42512319 | ||
| Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs. | Q48422889 | ||
| Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. | Q52195684 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Endothelial PAS domain protein 1 | Q21981067 |
| Hypoxia inducible factor 1, alpha subunit | Q21981069 | ||
| P304 | page(s) | 2301–2306 | |
| P577 | publication date | 2007-02-13 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Acute postnatal ablation of Hif-2alpha results in anemia | |
| P478 | volume | 104 |
| Q33576042 | A central role for hypoxic signaling in cartilage, bone, and hematopoiesis |
| Q24654396 | A gain-of-function mutation in the HIF2A gene in familial erythrocytosis |
| Q51148340 | A genetic variation associated with plasma erythropoietin and a non-coding transcript of PRKAR1A in sickle cell disease. |
| Q37333699 | A knock-in mouse model of human PHD2 gene-associated erythrocytosis establishes a haploinsufficiency mechanism |
| Q37227510 | A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition. |
| Q44492451 | A mouse model of adult-onset anaemia due to erythropoietin deficiency. |
| Q36605344 | A novel EPAS1/HIF2A germline mutation in a congenital polycythemia with paraganglioma |
| Q35408740 | A versatile modular vector system for rapid combinatorial mammalian genetics |
| Q37619809 | AMPKα1 deletion in fibroblasts promotes tumorigenesis in athymic nude mice by p52-mediated elevation of erythropoietin and CDK2. |
| Q36683947 | AP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development. |
| Q37457670 | Activation of hypoxia-inducible factor-2 in adipocytes results in pathological cardiac hypertrophy |
| Q91903913 | Acute and chronic hypoxia differentially predispose lungs for metastases |
| Q37487004 | Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2. |
| Q41675111 | Adeno-associated viral vector-mediated hypoxia-regulated VEGF gene transfer promotes angiogenesis following focal cerebral ischemia in mice |
| Q37721594 | Adipocyte pseudohypoxia suppresses lipolysis and facilitates benign adipose tissue expansion. |
| Q46017879 | An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression. |
| Q35836904 | Anaemia in kidney disease: harnessing hypoxia responses for therapy |
| Q90720906 | Anemia of Inflammation with An Emphasis on Chronic Kidney Disease |
| Q92037110 | Assessing the effect of hypoxia on cardiac metabolism using hyperpolarized 13 C magnetic resonance spectroscopy |
| Q59796441 | Astrocyte HIF-2α supports learning in a passive avoidance paradigm under hypoxic stress |
| Q41457604 | Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina |
| Q35670643 | Astrocyte pVHL and HIF-α isoforms are required for embryonic-to-adult vascular transition in the eye |
| Q90366870 | At the crossroads of oxygen and iron sensing: hepcidin control of HIF-2α |
| Q36210910 | BNip3 regulates mitochondrial function and lipid metabolism in the liver. |
| Q37079716 | Biology of hypoxia-inducible factor-2alpha in development and disease |
| Q41822735 | Canonical Wnt/β-catenin signaling is required for maintenance but not activation of Pitx2 expression in neural crest during eye development |
| Q42380466 | Cardiovascular adaptation to hypoxia and the role of peripheral resistance |
| Q37054884 | Carrot and stick: HIF-alpha engages c-Myc in hypoxic adaptation |
| Q35889114 | Cells of renin lineage express hypoxia inducible factor 2α following experimental ureteral obstruction |
| Q89454442 | Cellular adaptation to oxygen deficiency beyond the Nobel award |
| Q30360469 | Chronic hypoxia-inducible transcription factor-2 activation stably transforms juxtaglomerular renin cells into fibroblast-like cells in vivo. |
| Q34420371 | Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha |
| Q36999068 | Control of erythropoietin gene expression and its use in medicine |
| Q98735744 | Cross-Species Insights Into Genomic Adaptations to Hypoxia |
| Q38064316 | Crossing paths in Human Renal Cell Carcinoma (hRCC). |
| Q36515155 | DNA methyltransferase inhibition restores erythropoietin production in fibrotic murine kidneys. |
| Q33652089 | Defective Tibetan PHD2 binding to p23 links high altitude adaption to altered oxygen sensing |
| Q33685179 | Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis |
| Q40969375 | Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin |
| Q85238646 | Dual control: the HIF-2 regulator |
| Q99637298 | Dynamic regulation of hypoxia-inducible factor-1α activity is essential for normal B cell development |
| Q33868876 | EPAS1 Is Required for Spermatogenesis in the Postnatal Mouse Testis |
| Q83587545 | Effect of N-acetyl-cysteine and hyperoxia on erythropoietin production |
| Q38672565 | Effect of hypoxia-inducible factors in normal and leukemic stem cell regulation and their potential therapeutic impact. |
| Q47776165 | Endothelial Epas1 Deficiency Is Sufficient To Promote Parietal Epithelial Cell Activation and FSGS in Experimental Hypertension. |
| Q33883920 | Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury. |
| Q35858012 | Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes |
| Q35906539 | Endothelial cell HIF-1α and HIF-2α differentially regulate metastatic success |
| Q37271066 | Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis |
| Q37489539 | Endothelial oxygen sensors regulate tumor vessel abnormalization by instructing phalanx endothelial cells. |
| Q36980048 | Enhanceosomes as integrators of hypoxia inducible factor (HIF) and other transcription factors in the hypoxic transcriptional response. |
| Q39902159 | Epidermal sensing of oxygen is essential for systemic hypoxic response |
| Q36548712 | Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth |
| Q36928937 | Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation |
| Q34127573 | Erythropoiesis and Iron Sulfur Cluster Biogenesis |
| Q37098040 | Erythropoietic agents and the elderly |
| Q86260187 | Erythropoietin |
| Q86893314 | Erythropoietin |
| Q41863032 | Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling. |
| Q35909929 | Erythropoietin in brain development and beyond |
| Q54193060 | Erythropoietin production by PDGFR-β(+) cells. |
| Q37524229 | Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal |
| Q34781591 | Extracellular matrix genes as hypoxia-inducible targets |
| Q37683399 | FGF-23 is a negative regulator of prenatal and postnatal erythropoiesis |
| Q33569726 | FM19G11, a new hypoxia-inducible factor (HIF) modulator, affects stem cell differentiation status. |
| Q36837871 | Familial erythrocytosis arising from a gain-of-function mutation in the HIF2A gene of the oxygen sensing pathway. |
| Q46915042 | Fibrosis and hypoxia-inducible factor-1α-dependent tumors of the soft tissue on loss of von Hippel-Lindau in mesenchymal progenitors |
| Q82718177 | Functional evidence confirmed by histological localization: overlapping expression of erythropoietin and HIF-2alpha in interstitial fibroblasts of the renal cortex |
| Q33573521 | Gene panel sequencing improves the diagnostic work-up of patients with idiopathic erythrocytosis and identifies new mutations |
| Q37185770 | Genetic causes of erythrocytosis and the oxygen-sensing pathway |
| Q35878131 | HIF modulation of Wnt signaling regulates skeletal myogenesis in vivo. |
| Q37810073 | HIF pathway mutations and erythrocytosis |
| Q28307377 | HIF prolyl hydroxylase inhibitors for anemia |
| Q50020268 | HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice |
| Q37245540 | HIF-1 and ventilatory acclimatization to chronic hypoxia |
| Q98513545 | HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice |
| Q33404963 | HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis |
| Q34069429 | HIF-2alpha deletion promotes Kras-driven lung tumor development. |
| Q42171228 | HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice. |
| Q40526769 | HIF-2α in Resting Macrophages Tempers Mitochondrial Reactive Oxygen Species To Selectively Repress MARCO-Dependent Phagocytosis |
| Q55338865 | HIF-2α is essential for carotid body development and function. |
| Q33926530 | HIF-prolyl hydroxylases as therapeutic targets in erythropoiesis and iron metabolism |
| Q37164162 | HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury |
| Q27025886 | HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression |
| Q37286696 | HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice |
| Q89134572 | HIF2α in the uterine stroma permits embryo invasion and luminal epithelium detachment |
| Q37161630 | HIF2α-arginase axis is essential for the development of pulmonary hypertension. |
| Q34282364 | Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia. |
| Q37254917 | Heterozygosity for hypoxia inducible factor 1alpha decreases the incidence of thymic lymphomas in a p53 mutant mouse model |
| Q89506754 | Hidden features: exploring the non-canonical functions of metabolic enzymes |
| Q45731347 | Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance |
| Q91151745 | Hif1a and Hif2a can be safely inactivated in cone photoreceptors |
| Q88391692 | Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress |
| Q37679370 | Human adaptation to the hypoxia of high altitude: the Tibetan paradigm from the pregenomic to the postgenomic era. |
| Q42225364 | Human cytomegalovirus inhibits erythropoietin production. |
| Q34360748 | Human high-altitude adaptation: forward genetics meets the HIF pathway. |
| Q38870765 | Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes. |
| Q64086693 | Hypoxia and Hypoxia-Inducible Factors in Kidney Injury and Repair |
| Q37573701 | Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function. |
| Q37008513 | Hypoxia and the HIF system in kidney disease |
| Q92002424 | Hypoxia inducible factor 1α in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitment |
| Q37376637 | Hypoxia inducible factor-2alpha: a critical mediator of aggressive tumor phenotypes |
| Q24301382 | Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition |
| Q33619166 | Hypoxia regulates BMP4 expression in the murine spleen during the recovery from acute anemia |
| Q57618981 | Hypoxia-Inducible Factor 2α Plays a Critical Role in the Formation of Alveoli and Surfactant |
| Q38740776 | Hypoxia-Inducible Factor Stabilizers: a New Avenue for Reducing BP While Helping Hemoglobin? |
| Q48140646 | Hypoxia-Inducible Factor and Its Role in the Management of Anemia in Chronic Kidney Disease. |
| Q36137705 | Hypoxia-induced angiogenesis: good and evil |
| Q36844624 | Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration |
| Q37769765 | Hypoxia-inducible factor (HIF) and HIF-stabilizing agents in neonatal care |
| Q37302297 | Hypoxia-inducible factor 2 regulates hepatic lipid metabolism |
| Q34028645 | Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation |
| Q64118016 | Hypoxia-inducible factor 2α is a negative regulator of osteoblastogenesis and bone mass accrual |
| Q47785622 | Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development |
| Q36347766 | Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes. |
| Q49212691 | Hypoxia-inducible factor-1α is a critical transcription factor for IL-10-producing B cells in autoimmune disease |
| Q28585802 | Hypoxia-inducible factor-1α protein negatively regulates load-induced bone formation |
| Q35755184 | Hypoxia-inducible factor-1α restricts the anabolic actions of parathyroid hormone |
| Q28594830 | Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo |
| Q36953894 | Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice |
| Q43218010 | Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization |
| Q35754688 | Hypoxia-inducible factor-2α regulates Fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction |
| Q52596786 | Hypoxia-inducible factors 1alpha and 2alpha exert both distinct and overlapping functions in long bone development. |
| Q37688914 | Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen. |
| Q43094946 | Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function |
| Q24338684 | Hypoxia-inducible protein 2 is a novel lipid droplet protein and a specific target gene of hypoxia-inducible factor-1 |
| Q91812815 | Hypoxia: Overview on Hypoxia-Mediated Mechanisms with a Focus on the Role of HIF Genes |
| Q24609166 | Hypoxic regulation of erythropoiesis and iron metabolism |
| Q26824402 | Hypoxic signaling during tissue repair and regenerative medicine |
| Q38600513 | Impaired erythropoietin synthesis in chronic kidney disease is caused by alterations in extracellular matrix composition. |
| Q50454067 | Impaired expression of HIF-2α induces compensatory expression of HIF-1α for the recovery from anemia |
| Q42616754 | In cultured astrocytes, p53 and MDM2 do not alter hypoxia-inducible factor-1alpha function regardless of the presence of DNA damage |
| Q42941339 | In vivo analysis of gene knockdown in tetracycline-inducible shRNA mice. |
| Q50559572 | Inducible glomerular erythropoietin production in the adult kidney. |
| Q37431242 | Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease |
| Q37693210 | Inter-connection between mitochondria and HIFs |
| Q37506973 | Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis |
| Q42349433 | Is congenital secondary erythrocytosis/polycythemia caused by activating mutations within the HIF-2 alpha iron-responsive element? |
| Q27317145 | Isolation and characterization of renal erythropoietin-producing cells from genetically produced anemia mice |
| Q47423719 | JNK2 up-regulates hypoxia-inducible factors and contributes to hypoxia-induced erythropoiesis and pulmonary hypertension |
| Q42787068 | Landmark advances in the development of erythropoietin |
| Q52609121 | Late neuroprogenitors contribute to normal retinal vascular development in a Hif2a-dependent manner. |
| Q85732806 | Lipopolysaccharide-induced cross-tolerance against renal ischemia-reperfusion injury is mediated by hypoxia-inducible factor-2α-regulated nitric oxide production |
| Q27316066 | Loss of Hif-2α Rescues the Hif-1α Deletion Phenotype of Neonatal Respiratory Distress In Mice |
| Q41995211 | Loss of VHL in mesenchymal progenitors of the limb bud alters multiple steps of endochondral bone development |
| Q33874288 | Loss of fibroblast HIF-1α accelerates tumorigenesis. |
| Q37509308 | Microvascular pericytes in healthy and diseased kidneys |
| Q37779842 | Mitochondrial complex III: an essential component of universal oxygen sensing machinery? |
| Q89531122 | Modulation of sulfur assimilation metabolic toxicity overcomes anemia and hemochromatosis in mice |
| Q28297656 | Molecular mechanisms of action and therapeutic uses of pharmacological inhibitors of HIF-prolyl 4-hydroxylases for treatment of ischemic diseases |
| Q28080772 | Molecular mechanisms of ischemic preconditioning in the kidney |
| Q36823821 | Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function |
| Q37011956 | Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways |
| Q49022670 | Neuronal HIF-1α and HIF-2α deficiency improves neuronal survival and sensorimotor function in the early acute phase after ischemic stroke |
| Q35836151 | Neurovascular crosstalk between interneurons and capillaries is required for vision |
| Q64229990 | New insights into the links between hypoxia and iron homeostasis |
| Q35129302 | O2 regulates stem cells through Wnt/β-catenin signalling. |
| Q34111842 | Oligodendrocyte-encoded HIF function couples postnatal myelination and white matter angiogenesis |
| Q89575613 | Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors |
| Q39179833 | Overview of iron metabolism in health and disease |
| Q34538613 | Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche. |
| Q38961810 | Oxygen availability and metabolic adaptations |
| Q39770199 | Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling |
| Q35486453 | Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin |
| Q57377853 | PHD2 inactivation in Type I cells drives HIF-2α-dependent multilineage hyperplasia and the formation of paraganglioma-like carotid bodies |
| Q52979101 | Pathology of the Nervous System in Von Hippel-Lindau Disease. |
| Q90963815 | Pharmacologic Targeting of Hypoxia-Inducible Factors |
| Q35719850 | Pharmacological HIF2α inhibition improves VHL disease-associated phenotypes in zebrafish model |
| Q38327224 | Plasticity of renal endocrine function |
| Q90289997 | Population History and Altitude-Related Adaptation in the Sherpa |
| Q37374651 | Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets |
| Q34805681 | Prolyl hydroxylase domain protein 2 (PHD2) mediates oxygen-induced retinopathy in neonatal mice |
| Q37779100 | Prolyl hydroxylase domain-containing protein inhibitors as stabilizers of hypoxia-inducible factor: small molecule-based therapeutics for anemia |
| Q36950679 | Reactive oxygen species and cellular oxygen sensing |
| Q37298190 | Red blood cells in sports: effects of exercise and training on oxygen supply by red blood cells |
| Q111285544 | Regulation of Cancer Metabolism by Deubiquitinating Enzymes: The Warburg Effect |
| Q36491878 | Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins |
| Q24610063 | Regulation of cellular iron metabolism |
| Q37063716 | Regulation of erythropoiesis by hypoxia-inducible factors |
| Q36876347 | Regulation of gene expression by hypoxia: integration of the HIF-transduced hypoxic signal at the hypoxia-responsive element |
| Q37443475 | Regulation of oxygen homeostasis by hypoxia-inducible factor 1. |
| Q38685131 | Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway |
| Q38123955 | Renal anemia: from incurable to curable |
| Q35456356 | Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling |
| Q38531955 | Renal erythropoietin-producing cells in health and disease. |
| Q92560341 | Roles of HIFs and VEGF in angiogenesis in the retina and brain |
| Q30980340 | Roles of coactivators in hypoxic induction of the erythropoietin gene |
| Q50107305 | SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α. |
| Q31132835 | STAT3 or USF2 contributes to HIF target gene specificity |
| Q64900575 | Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation. |
| Q34293299 | Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1. |
| Q30361787 | Stress-associated erythropoiesis initiation is regulated by type 1 conventional dendritic cells. |
| Q35576516 | Suppression of erythropoiesis by dietary nitrate. |
| Q34725972 | Survival and proliferative roles of erythropoietin beyond the erythroid lineage |
| Q28513588 | Targeted deletion of Vegfa in adult mice induces vision loss |
| Q37794392 | Targeting Astrocytes for Stroke Therapy |
| Q36878827 | The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice. |
| Q91629225 | The Genomics and Genetics of Oxygen Homeostasis |
| Q37799606 | The HIF Pathway and Erythrocytosis |
| Q36127328 | The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO. |
| Q36728582 | The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption |
| Q37440360 | The Janus-faced effects of hypoxia on astrocyte function |
| Q36818360 | The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia. |
| Q36095810 | The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha |
| Q37064867 | The VHL tumor suppressor and HIF: insights from genetic studies in mice |
| Q24634592 | The VHL tumor suppressor: master regulator of HIF |
| Q35634874 | The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability. |
| Q37403106 | The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice. |
| Q34389604 | The homeodomain transcription factor PITX2 is required for specifying correct cell fates and establishing angiogenic privilege in the developing cornea |
| Q54454681 | The hypoxia inducible factor/erythropoietin (EPO)/EPO receptor pathway is disturbed in a rat model of chronic kidney disease related anemia. |
| Q28598099 | The role of PHD2 mutations in the pathogenesis of erythrocytosis |
| Q33876311 | The role of oxygen availability in embryonic development and stem cell function |
| Q39990999 | The specific contribution of hypoxia-inducible factor-2alpha to hypoxic gene expression in vitro is limited and modulated by cell type-specific and exogenous factors |
| Q39250750 | The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice. |
| Q36999054 | Transgenic models to understand hypoxia-inducible factor function. |
| Q34147522 | Transient ureteral obstruction prevents against kidney ischemia/reperfusion injury via hypoxia-inducible factor (HIF)-2α activation |
| Q35589987 | Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL. |
| Q90343897 | Updates on Novel Erythropoiesis-Stimulating Agents: Clinical and Molecular Approach |
| Q36362933 | Upstream stimulatory factor 2 and hypoxia-inducible factor 2α (HIF2α) cooperatively activate HIF2 target genes during hypoxia |
| Q54943750 | VHL and Hypoxia Signaling: Beyond HIF in Cancer. |
| Q34455226 | VHL, the story of a tumour suppressor gene |
| Q64051780 | iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications |
| Q48136998 | miRNAs regulate the HIF switch during hypoxia: a novel therapeutic target |
| Q36121776 | von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis |
| Q39404350 | von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina |
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