Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer

scientific article (publication date: 2010)

Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1032799121
P356DOI10.1186/BCR2635
P3181OpenCitations bibliographic resource ID548714
P932PMC publication ID3096954
P698PubMed publication ID20813035
P5875ResearchGate publication ID46123527

P50authorCharles M. PerouQ30503513
P2093author name stringFan C
He X
Herschkowitz JI
Karginova O
Livasy C
Parker JS
Prat A
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Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotypeQ40012189
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Mammary development meets cancer genomics.Q51928701
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ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcomeQ24657877
Prospective identification of tumorigenic breast cancer cellsQ24683474
Determination of stromal signatures in breast carcinomaQ24798099
DAVID: Database for Annotation, Visualization, and Integrated DiscoveryQ27499374
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implicationsQ27860709
Gene expression profiling predicts clinical outcome of breast cancerQ27860732
A gene-expression signature as a predictor of survival in breast cancerQ27860945
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cellQ27861001
Molecular portraits of human breast tumoursQ28032461
Systematic variation in gene expression patterns in human cancer cell linesQ28145747
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traitsQ28237197
Identification of selective inhibitors of cancer stem cells by high-throughput screeningQ28255115
Molecular definition of breast tumor heterogeneityQ28292256
Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristicsQ28751743
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumorsQ29615393
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cellsQ29616498
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Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating featuresQ29620020
Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signatureQ29622952
The molecular portraits of breast tumors are conserved across microarray platformsQ33241398
Cell-type specific gene expression profiles of leukocytes in human peripheral bloodQ33243638
EGFR associated expression profiles vary with breast tumor subtypeQ33292502
Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer.Q33638070
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumorsQ33896961
Two syngeneic cell lines from human breast tissue: the aneuploid mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578Bst) cell linesQ34382169
Concordance among gene-expression-based predictors for breast cancerQ34555829
A luminal epithelial stem cell that is a cell of origin for prostate cancerQ35001982
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumorsQ35906418
BRCA1 regulates human mammary stem/progenitor cell fateQ36446479
Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapyQ36678657
The fibromatosis signature defines a robust stromal response in breast carcinomaQ36841980
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectbreast cancerQ128581
P304page(s)R68
P577publication date2010-01-01
P1433published inBreast Cancer ResearchQ2208481
P1476titlePhenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
P478volume12

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Q36903234Embryonic mammary signature subsets are activated in Brca1-/- and basal-like breast cancers
Q35485571Emerging drug discovery approaches for selective targeting of "precursor" metastatic breast cancer cells: highlights and perspectives
Q26851833Emerging role of cell polarity proteins in breast cancer progression and metastasis
Q26799622Emerging roles for IL-11 signaling in cancer development and progression: Focus on breast cancer
Q37225107Emerging roles of claudins in human cancer
Q24621116Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts
Q64894187Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma.
Q37480166Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis.
Q47732435Engrailed 1 overexpression as a potential prognostic marker in quintuple-negative breast cancer
Q48863076Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex
Q36689065EpCAM based capture detects and recovers circulating tumor cells from all subtypes of breast cancer except claudin-low
Q27011535Epidemiology, biology, and treatment of triple-negative breast cancer in women of African ancestry
Q36286662Epigenetic mechanisms in commonly occurring cancers.
Q39439645Epithelial and mesenchymal subpopulations within normal basal breast cell lines exhibit distinct stem cell/progenitor properties
Q36145725Epithelial-Mesenchymal Transition Phenotype Is Associated with Clinicopathological Factors That Indicate Aggressive Biological Behavior and Poor Clinical Outcomes in Invasive Breast Cancer.
Q26859804Epithelial-mesenchymal plasticity in carcinoma metastasis
Q26824386Epithelial-mesenchymal plasticity of breast cancer stem cells: implications for metastasis and therapeutic resistance
Q35029475Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression
Q39085731Epithelial-mesenchymal transition in tumor metastasis
Q34880376Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients.
Q57109975Epithelial-to-mesenchymal transition and cancer stem cells contribute to breast cancer heterogeneity
Q37200831ErbB3 downregulation enhances luminal breast tumor response to antiestrogens
Q37524229Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal
Q34268870Essential gene profiles in breast, pancreatic, and ovarian cancer cells.
Q38883472Establishment of an mKate2-Expressing Cell Line for Non-Invasive Real-Time Breast Cancer In Vivo Imaging
Q52730161Establishment of two basal-like breast cancer cell lines with extremely low tumorigenicity from Taiwanese premenopausal women.
Q45073978Estrogen induces c-Kit and an aggressive phenotype in a model of invasive lobular breast cancer
Q55687390Estrogen promotes estrogen receptor negative BRCA1-deficient tumor initiation and progression.
Q33848950Estrogen receptor-α, progesterone receptor, and c-erbB/HER-family receptor mRNA detection and phenotype analysis in spontaneous canine models of breast cancer
Q64054816Evaluating cell lines as models for metastatic breast cancer through integrative analysis of genomic data
Q35503492Evaluation of public cancer datasets and signatures identifies TP53 mutant signatures with robust prognostic and predictive value
Q35979379Exometabolom analysis of breast cancer cell lines: Metabolic signature
Q34820412Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways
Q28066481Exploring circulating micro-RNA in the neoadjuvant treatment of breast cancer
Q36924443Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways.
Q42510313Expression of calretinin in high-grade hormone receptor-negative invasive breast carcinomas: correlation with histological and molecular subtypes.
Q37625774Expression of human endogenous retrovirus-K is strongly associated with the basal-like breast cancer phenotype.
Q36042570Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential
Q38708750Expression of tripartite motif-containing protein 28 in primary breast carcinoma predicts metastasis and is involved in the stemness, chemoresistance, and tumor growth
Q48141048Expression patterns of claudins in patients with triple-negative breast cancer are associated with nodal metastasis and worse outcome
Q21195201Expression profiling of cancerous and normal breast tissues identifies microRNAs that are differentially expressed in serum from patients with (metastatic) breast cancer and healthy volunteers
Q36204224FGFR signaling promotes the growth of triple-negative and basal-like breast cancer cell lines both in vitro and in vivo
Q37689013FOXC1 identifies basal-like breast cancer in a hereditary breast cancer cohort
Q36698254FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer.
Q44076458Fatty acid synthase expression and its association with clinico-histopathological features in triple-negative breast cancer
Q35182598Fibromatosis-like metaplastic carcinoma of the breast has a claudin-low immunohistochemical phenotype
Q34310997Field cancerization in mammary carcinogenesis - Implications for prevention and treatment of breast cancer
Q36496096Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance
Q26861636Functional Role of the microRNA-200 Family in Breast Morphogenesis and Neoplasia
Q52714523Functional and genomic characterization of a xenograft model system for the study of metastasis in triple-negative breast cancer.
Q37457902Functional and prognostic significance of long non-coding RNA MALAT1 as a metastasis driver in ER negative lymph node negative breast cancer
Q50790658Functional characterization of selective exosite-binding inhibitors of matrix metalloproteinase-13 (MMP-13) - experimental validation in human breast and colon cancer.
Q38335759Functional roles of alternative splicing factors in human disease
Q35980816G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis
Q35858016G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer
Q64117140GALNT3 Maintains the Epithelial State in Trophoblast Stem Cells
Q33761830GD2 expression in breast cancer.
Q89457584GD2-targeted chimeric antigen receptor T cells prevent metastasis formation by elimination of breast cancer stem-like cells
Q34704073GOBO: gene expression-based outcome for breast cancer online
Q89997351GSK2801, a BAZ2/BRD9 Bromodomain Inhibitor, Synergizes with BET Inhibitors to Induce Apoptosis in Triple-Negative Breast Cancer
Q91980872Gene Expression and miRNAs Profiling: Function and Regulation in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
Q35091690Gene co-expression modules as clinically relevant hallmarks of breast cancer diversity
Q36245556Gene expression in extratumoral microenvironment predicts clinical outcome in breast cancer patients.
Q35551926Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features
Q37528475Gene expression profiles of inflammatory breast cancer: correlation with response to neoadjuvant chemotherapy and metastasis-free survival
Q37958156Gene expression profiling in breast cancer: classification, prognostication, and prediction
Q37169835Gene expression profiling: changing face of breast cancer classification and management
Q41136273Gene expression-based classifications of fibroadenomas and phyllodes tumours of the breast
Q35314135Gene-expression molecular subtyping of triple-negative breast cancer tumours: importance of immune response
Q40274876Genefu: an R/Bioconductor package for computation of gene expression-based signatures in breast cancer.
Q35683564Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor.
Q38862963Genetic Alterations in the Molecular Subtypes of Bladder Cancer: Illustration in the Cancer Genome Atlas Dataset
Q92541740Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
Q91890943Genetic determinants of the molecular portraits of epithelial cancers
Q36846498Genetic susceptibility to triple-negative breast cancer
Q33720872Genome organizing function of SATB1 in tumor progression
Q36289944Genome-wide effects of MELK-inhibitor in triple-negative breast cancer cells indicate context-dependent response with p53 as a key determinant
Q34577891Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer.
Q35079683Genomic analyses across six cancer types identify basal-like breast cancer as a unique molecular entity
Q54481772Genomic analyses to select patients for adjuvant chemotherapy: trials and tribulations.
Q34192343Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse.
Q58574264Genomic analysis of racial differences in triple negative breast cancer
Q36753689Genomic and phenotypic profiles of two Brazilian breast cancer cell lines derived from primary human tumors
Q47156532Genomic and transcriptomic heterogeneity in metaplastic carcinomas of the breast
Q42486311Genomic predictors of response to doxorubicin versus docetaxel in primary breast cancer
Q53085136Genomic profiling of histological special types of breast cancer.
Q89267498Genomic profiling of metaplastic breast carcinomas reveals genetic heterogeneity and relationship to ductal carcinoma
Q37120418Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers.
Q35694382Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer
Q39319266Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes
Q91968762Global gene expression profile in canine mammary carcinomas
Q59795540Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis
Q37596851Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target
Q37014479Glycoprotein non-metastatic b (GPNMB): A metastatic mediator and emerging therapeutic target in cancer.
Q41411741Glycoproteins in Claudin-Low Breast Cancer Cell Lines Have a Unique Expression Profile.
Q35285329Growth and metastatic behavior of molecularly well-characterized human breast cancer cell lines in mice
Q28085413HER2 and uPAR cooperativity contribute to metastatic phenotype of HER2-positive breast cancer
Q38925408Hereditary breast and ovarian cancer: new genes in confined pathways
Q35551911Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.
Q35802450Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways
Q92934298Heterogeneity in Circulating Tumor Cells: The Relevance of the Stem-Cell Subset
Q42942060Heterogeneity in breast cancer
Q37956043Heterogeneity of breast cancer: etiology and clinical relevance
Q52684723High-level cytoplasmic claudin 3 expression is an independent predictor of poor survival in triple-negative breast cancer.
Q37573642High-throughput gene expression and mutation profiling: current methods and future perspectives.
Q53241145Histologic subtypes of breast cancer following radiotherapy for Hodgkin lymphoma.
Q48218331Histological subtypes of mouse mammary tumors reveal conserved relationships to human cancers
Q34616569Histological, molecular and functional subtypes of breast cancers
Q41664067Histone Deacetylases as New Therapeutic Targets in Triple-negative Breast Cancer: Progress and Promises
Q34119025Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures
Q99408079Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer
Q28077637Hormonal Modulation of Breast Cancer Gene Expression: Implications for Intrinsic Subtyping in Premenopausal Women
Q36551617Human epidermal growth factor receptor-2-positive breast cancer: does estrogen receptor status define two distinct subtypes?
Q36473360Hypomethylation of the MMP7 promoter and increased expression of MMP7 distinguishes the basal-like breast cancer subtype from other triple-negative tumors
Q38659248ICRP Publication 131: Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection
Q38894487ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype
Q94588123IGF1R constitutive activation expands luminal progenitors and influences lineage differentiation during breast tumorigenesis
Q39259470IL-2- or IL-15-activated NK cells enhance Cetuximab-mediated activity against triple-negative breast cancer in xenografts and in breast cancer patients
Q55268231IMP3 Stabilization of WNT5B mRNA Facilitates TAZ Activation in Breast Cancer.
Q36714784ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models
Q36232146Identification and evaluation of network modules for the prognosis of basal-like breast cancer
Q33874621Identification and use of biomarkers in treatment strategies for triple-negative breast cancer subtypes
Q33975444Identification of a novel luminal molecular subtype of breast cancer
Q33645711Identification of a stable molecular signature in mammary tumor endothelial cells that persists in vitro
Q90480579Identification of candidate RNA signatures in triple-negative breast cancer by the construction of a competing endogenous RNA network with integrative analyses of Gene Expression Omnibus and The Cancer Genome Atlas data
Q38875037Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis.
Q29617680Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
Q36041569Identification of intrinsic imaging phenotypes for breast cancer tumors: preliminary associations with gene expression profiles
Q57490070Identification of miR-200c and miR141-Mediated lncRNA-mRNA Crosstalks in Muscle-Invasive Bladder Cancer Subtypes
Q42505597Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive.
Q34972623Identification of the YES1 Kinase as a Therapeutic Target in Basal-Like Breast Cancers
Q26851827Identifying and targeting tumor-initiating cells in the treatment of breast cancer
Q60915327Identifying genes with tri-modal association with survival and tumor grade in cancer patients
Q30965908Identifying network biomarkers based on protein-protein interactions and expression data
Q38241276Illuminating breast cancer invasion: diverse roles for cell-cell interactions
Q55032160Immune Landscape of Breast Cancers.
Q33761491Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis
Q64999098Immunoexpression of claudins 4 and 7 among invasive breast carcinoma subtypes: A large diagnostic study using tissue microarray.
Q33684982Immunoexpression of lactoferrin in triple-negative breast cancer patients: A proposal to select a less aggressive subgroup
Q92625382Immunohistochemical Expression of Vimentin in Invasive Breast Carcinoma and Its Correlation with Clinicopathological Parameters
Q36778827Immunotherapeutic approaches in triple-negative breast cancer: latest research and clinical prospects
Q90402359Impact of chemotherapy on the expression of claudins and cadherins in invasive breast cancer
Q33739253Impact of hormone receptor status on patterns of recurrence and clinical outcomes among patients with human epidermal growth factor-2-positive breast cancer in the National Comprehensive Cancer Network: a prospective cohort study
Q36935015Impact of tumor microenvironment and epithelial phenotypes on metabolism in breast cancer
Q38862416Impairment of human neural crest cell migration by prolonged exposure to interferon-beta.
Q37872301Implications of genomic instability in the diagnosis and treatment of breast cancer
Q26799987Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis
Q34720254Improving breast cancer survival analysis through competition-based multidimensional modeling
Q34764103In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneity.
Q34564798Inactivation of RARβ inhibits Wnt1-induced mammary tumorigenesis by suppressing epithelial-mesenchymal transitions.
Q33727273Increased macroH2A1.1 expression correlates with poor survival of triple-negative breast cancer patients
Q36545999Increased metastasis with loss of E2F2 in Myc-driven tumors
Q37651843Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours.
Q37588310Induction of HOXA9 expression in three-dimensional organotypic culture of the Claudin-low breast cancer cells
Q36545233Induction of USP17 by combining BET and HDAC inhibitors in breast cancer cells
Q47137189Induction of a novel isoform of the lncRNA HOTAIR in Claudin-low breast cancer cells attached to extracellular matrix
Q30571243Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent
Q36732552Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression.
Q39315724Information theoretic sub-network mining characterizes breast cancer subtypes in terms of cancer core mechanisms
Q41612992Inhibition of FAK kinase activity preferentially targets cancer stem cells
Q42101498Inhibition of proliferation and migration of luminal and claudin-low breast cancer cells by PDGFR inhibitors
Q27853151Inhibition of the phosphoinositide 3-kinase pathway for the treatment of patients with metastatic metaplastic breast cancer.
Q37642845Ink4a/Arf(-/-) and HRAS(G12V) transform mouse mammary cells into triple-negative breast cancer containing tumorigenic CD49f(-) quiescent cells.
Q35962810Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer
Q92092227Integrated analyses of murine breast cancer models reveal critical parallels with human disease
Q58797844Integrative analysis of the inter-tumoral heterogeneity of triple-negative breast cancer
Q37605645Integrative exploration of genomic profiles for triple negative breast cancer identifies potential drug targets.
Q36754194Integrative physical oncology
Q41471118Interaction of glycosphingolipids GD3 and GD2 with growth factor receptors maintains breast cancer stem cell phenotype
Q36989015Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer.
Q37234841Interactions between immunity, proliferation and molecular subtype in breast cancer prognosis
Q92989981Interrogation of Phenotypic Plasticity between Epithelial and Mesenchymal States in Breast Cancer
Q35203271Intra-tumour signalling entropy determines clinical outcome in breast and lung cancer
Q38709186Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breast cancer.
Q42506362Intrinsic Subtypes and Gene Expression Profiles in Primary and Metastatic Breast Cancer.
Q38222834Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer
Q58053534Intrinsic cancer subtypes-next steps into personalized medicine
Q55078504Intrinsic subtypes and bladder cancer metastasis.
Q37612632Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology
Q35576242Invasive Breast Cancer: Recognition of Molecular Subtypes
Q35025646Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics
Q34476337Is the future of personalized therapy in triple-negative breast cancer based on molecular subtype?
Q36490203Is there an epigenetic component underlying the resistance of triple-negative breast cancers to parp inhibitors?
Q47697280Isolation of Breast cancer CTCs with multitargeted buoyant immunomicrobubbles
Q36245402JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer.
Q52347720KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer.
Q64445673KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals
Q24296484KIF14 promotes AKT phosphorylation and contributes to chemoresistance in triple-negative breast cancer
Q35964972Kaiso depletion attenuates transforming growth factor-β signaling and metastatic activity of triple-negative breast cancer cells
Q90010879LINC01638 lncRNA activates MTDH-Twist1 signaling by preventing SPOP-mediated c-Myc degradation in triple-negative breast cancer
Q37055054Lactate dehydrogenase B: a metabolic marker of response to neoadjuvant chemotherapy in breast cancer
Q36741528Latest research progress in the correlation between baicalein and breast cancer invasion and metastasis
Q36058024Lectin chromatography/mass spectrometry discovery workflow identifies putative biomarkers of aggressive breast cancers
Q38213543Lessons learned from the intrinsic subtypes of breast cancer in the quest for precision therapy
Q52723870Leukotriene Receptor Antagonists Inhibit Mitogenic Activity in Triple Negative Breast Cancer Cells
Q92442312Lipid Droplets Define a Sub-Population of Breast Cancer Stem Cells
Q21132473Long chain fatty Acyl-CoA synthetase 4 is a biomarker for and mediator of hormone resistance in human breast cancer
Q34556770Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer.
Q35995591Loss of Panx1 Impairs Mammary Gland Development at Lactation: Implications for Breast Tumorigenesis
Q37549104Loss of WISP2/CCN5 in estrogen-dependent MCF7 human breast cancer cells promotes a stem-like cell phenotype
Q34133391Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasis
Q98771231Low Expression of Claudin-7 as Potential Predictor of Distant Metastases in High-Grade Serous Ovarian Carcinoma Patients
Q37299331Low expression of galectin-3 is associated with poor survival in node-positive breast cancers and mesenchymal phenotype in breast cancer stem cells
Q58774122Low serum gastrin associated with ER breast cancer development via inactivation of CCKBR/ERK/P65 signaling
Q36513217Luminal B tumors are the most frequent molecular subtype in breast cancer of North African women: an immunohistochemical profile study from Morocco
Q35020412Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy
Q41667225Lunatic Fringe and p53 Cooperatively Suppress Mesenchymal Stem-Like Breast Cancer
Q36702175Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.
Q34961989MAP3K4/CBP-regulated H2B acetylation controls epithelial-mesenchymal transition in trophoblast stem cells
Q48231466MCL-1 is a prognostic indicator and drug target in breast cancer
Q33657478MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ERα)-positive mammary adenocarcinomas
Q38135451MR imaging features of triple-negative breast cancers
Q49272521MUC1 induces M2 type macrophage influx during postpartum mammary gland involution and triggers breast cancer
Q37014197MYC Is a Crucial Mediator of TGFβ-Induced Invasion in Basal Breast Cancer
Q92669420MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer
Q90083168Machine-Learning Prediction of Tumor Antigen Immunogenicity in the Selection of Therapeutic Epitopes
Q35800693Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs.
Q35779391Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch
Q47147401Mammalian sterile 20-like kinase 1 expression and its prognostic significance in patients with breast cancer.
Q57112976Mammary Stem Cells and Breast Cancer Stem Cells: Molecular Connections and Clinical Implications
Q26830779Mammary gland stem cells: more puzzles than explanations
Q27003345Mammary stem cells and the differentiation hierarchy: current status and perspectives
Q89700474Mammary stem cells: angels or demons in mammary gland?
Q35661710Mammary tumors that become independent of the type I insulin-like growth factor receptor express elevated levels of platelet-derived growth factor receptors
Q35155460Management options in triple-negative breast cancer
Q37190619Manganese Superoxide Dismutase Expression Regulates the Switch Between an Epithelial and a Mesenchymal-Like Phenotype in Breast Carcinoma
Q37734011Manganese superoxide dismutase is a promising target for enhancing chemosensitivity of basal-like breast carcinoma.
Q35612277Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction.
Q52805550Matrix metalloproteinase-9 (MMP9) is involved in the TNF-α-induced fusion of human M13SV1-Cre breast epithelial cells and human MDA-MB-435-pFDR1 cancer cells.
Q28084024Mechanisms involved in breast cancer liver metastasis
Q92826406Mechanisms of Chemotherapy Resistance in Triple-Negative Breast Cancer-How We Can Rise to the Challenge
Q47176980Mesenchymal phenotype of circulating tumor cells is associated with distant metastasis in breast cancer patients
Q36472268Mesenchymal traits are selected along with stem features in breast cancer cells grown as mammospheres
Q27316936Met kinetic signature derived from the response to HGF/SF in a cellular model predicts breast cancer patient survival
Q36747465Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer
Q37363521Meta-Analysis of the Luminal and Basal Subtypes of Bladder Cancer and the Identification of Signature Immunohistochemical Markers for Clinical Use
Q38696301Metabolic reprogramming underlies metastatic potential in an obesity-responsive murine model of metastatic triple negative breast cancer
Q34283295Metabolic syndrome-breast cancer link varies by intrinsic molecular subtype
Q42513445Metalloprotease-dependent activation of EGFR modulates CD44+/CD24- populations in triple negative breast cancer cells through the MEK/ERK pathway.
Q37620891Metalloprotease-disintegrin ADAM12 actively promotes the stem cell-like phenotype in claudin-low breast cancer
Q37352137Metalloproteinase-disintegrin ADAM12 is associated with a breast tumor-initiating cell phenotype.
Q38359372Metaplastic breast cancer: clinical overview and molecular aberrations for potential targeted therapy
Q35911470Metaplastic breast carcinomas display genomic and transcriptomic heterogeneity [corrected]. .
Q42467629Metaplastic carcinoma show different expression pattern of YAP compared to triple-negative breast cancer.
Q38641240Metastatic triple negative breast cancer: Optimizing treatment options, new and emerging targeted therapies
Q38790790Metformin attenuates transforming growth factor beta (TGF-β) mediated oncogenesis in mesenchymal stem-like/claudin-low triple negative breast cancer.
Q36143153Methylation profile of triple-negative breast carcinomas
Q37190321MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer
Q35000619MiR-183/-96/-182 cluster is up-regulated in most breast cancers and increases cell proliferation and migration
Q39095883MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways.
Q30539640MicroRNA 9-3p targets β1 integrin to sensitize claudin-low breast cancer cells to MEK inhibition
Q34462262MicroRNA-200 family modulation in distinct breast cancer phenotypes
Q37044582MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11.
Q36641467MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion.
Q37746031MicroRNA-455-3p promotes invasion and migration in triple negative breast cancer by targeting tumor suppressor EI24.
Q34299430MicroRNA93 regulates proliferation and differentiation of normal and malignant breast stem cells.
Q26862716MicroRNAs and triple negative breast cancer
Q26823360MicroRNAs in breast cancer initiation and progression
Q35558070Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction
Q38848773Microelectrode bioimpedance analysis distinguishes basal and claudin-low subtypes of triple negative breast cancer cells
Q39509229Migration of MDA-MB-231 breast cancer cells depends on the availability of exogenous lipids and cholesterol esterification.
Q26748850Minimal residual disease in breast cancer: an overview of circulating and disseminated tumour cells
Q36790655Mitochondrial ATAD3A combines with GRP78 to regulate the WASF3 metastasis-promoting protein
Q41260173Mitochondrial DNA content in breast cancer: Impact on in vitro and in vivo phenotype and patient prognosis
Q61816625Modeling Tumor Phenotypes In Vitro with Three-Dimensional Bioprinting
Q39248988Modeling and characterization of inflammatory breast cancer emboli grown in vitro
Q64109139Modeling differentiation-state transitions linked to therapeutic escape in triple-negative breast cancer
Q38078338Molecular alterations in metaplastic breast carcinoma
Q38133084Molecular and cellular heterogeneity in breast cancer: challenges for personalized medicine
Q39399933Molecular and clinicopathological markers of prognosis in breast cancer.
Q35684581Molecular basis of triple negative breast cancer and implications for therapy
Q34476551Molecular characterisation of cell line models for triple-negative breast cancers
Q35530143Molecular characterization and targeted therapeutic approaches in breast cancer
Q36630430Molecular characterization of basal-like and non-basal-like triple-negative breast cancer
Q33750808Molecular characterization of breast cancer cell lines by clinical immunohistochemical markers.
Q38216166Molecular classification of breast cancer
Q42451288Molecular classification of metaplastic carcinoma using surrogate immunohistochemical staining.
Q46131870Molecular classification of triple-negative tumors
Q35928897Molecular portrait of breast cancer in China reveals comprehensive transcriptomic likeness to Caucasian breast cancer and low prevalence of luminal A subtype.
Q36099968Molecular portraits revealing the heterogeneity of breast tumor subtypes defined using immunohistochemistry markers
Q37302484Molecular profiling for breast cancer: a comprehensive review
Q54403385Molecular prognostic and predictive markers of breast cancer treatment
Q91973648Molecular stratification within triple-negative breast cancer subtypes
Q38061108Molecular subclasses of breast cancer: how do we define them? The IMPAKT 2012 Working Group Statement.
Q47374603Molecular subtyping of breast cancer improves identification of both high and low risk patients.
Q38184381Molecular tests as prognostic factors in breast cancer
Q38998265Mouse Models of Breast Cancer Share Amplification and Deletion Events with Human Breast Cancer
Q42770299Mouse models and anti-HER2 therapies
Q59791901Moving Breast Cancer Therapy up a Notch
Q92730905Multi-Omics Characterization of the Spontaneous Mesenchymal-Epithelial Transition in the PMC42 Breast Cancer Cell Lines
Q42514809Multidimensional phenotyping of breast cancer cell lines to guide preclinical research
Q34123261Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin
Q36165196Multipotent luminal mammary cancer stem cells model tumor heterogeneity
Q35206221Murine mammary tumor cells with a claudin-low genotype
Q37066581Murine microenvironment metaprofiles associate with human cancer etiology and intrinsic subtypes
Q36219957Mutant PIK3CA Induces EMT in a Cell Type Specific Manner
Q37143534Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies
Q34654793Mutational profiles in triple-negative breast cancer defined by ultradeep multigene sequencing show high rates of PI3K pathway alterations and clinically relevant entity subgroup specific differences
Q34248585Myc is required for β-catenin-mediated mammary stem cell amplification and tumorigenesis
Q59128928NMT1 inhibition modulates breast cancer progression through stress-triggered JNK pathway
Q89910309NOTCH4 maintains quiescent mesenchymal-like breast cancer stem cells via transcriptionally activating SLUG and GAS1 in triple-negative breast cancer
Q91587906Nanoparticle-Encapsulated Doxorubicin Demonstrates Superior Tumor Cell Kill in Triple Negative Breast Cancer Subtypes Intrinsically Resistant to Doxorubicin
Q55633505Nanoparticle-Mediated Therapeutic Agent Delivery for Treating Metastatic Breast Cancer-Challenges and Opportunities.
Q55043805Natural Products for the Management and Prevention of Breast Cancer.
Q58795373Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancer
Q50093673NeoPalAna: Neoadjuvant Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, and Anastrozole for Clinical Stage 2 or 3 Estrogen Receptor-Positive Breast Cancer
Q91941572Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer
Q37568043Neuregulin autocrine signaling promotes self-renewal of breast tumor-initiating cells by triggering HER2/HER3 activation.
Q49900625Neutralization of IL-8 decreases tumor PMN-MDSCs and reduces mesenchymalization of claudin-low triple-negative breast cancer
Q38074564New biological insights on the link between radiation exposure and breast cancer risk
Q37094064New generation of breast cancer clinical trials implementing molecular profiling
Q42837223New light on Smac mimetics and breast cancer
Q34634272Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity
Q89597721Non-Coding RNAs as Regulators and Markers for Targeting of Breast Cancer and Cancer Stem Cells
Q89574633Normal Breast-Derived Epithelial Cells with Luminal and Intrinsic Subtype-Enriched Gene Expression Document Interindividual Differences in Their Differentiation Cascade
Q44063727Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a-LCOR axis
Q36397832Normal cell phenotypes of breast epithelial cells provide the foundation of a breast cancer taxonomy
Q58544241Notch and Wnt Dysregulation and Its Relevance for Breast Cancer and Tumor Initiation
Q55429263Novel antibody reagents for characterization of drug- and tumor microenvironment-induced changes in epithelial-mesenchymal transition and cancer stem cells.
Q34285190Novel role of Engrailed 1 as a prosurvival transcription factor in basal-like breast cancer and engineering of interference peptides block its oncogenic function.
Q33887682Novel therapeutic strategies in the treatment of triple-negative breast cancer
Q92541751OSbrca: A Web Server for Breast Cancer Prognostic Biomarker Investigation With Massive Data From Tens of Cohorts
Q58765189Obesity promotes the expansion of metastasis-initiating cells in breast cancer
Q39355041Oncogenic PI3K mutations lead to NF-κB-dependent cytokine expression following growth factor deprivation
Q38215948Oncogenic roles of EMT-inducing transcription factors
Q51069613Oncostatin-M promotes phenotypic changes associated with mesenchymal and stem cell-like differentiation in breast cancer.
Q36047389Osteopontin regulates proliferation, apoptosis, and migration of murine claudin-low mammary tumor cells
Q89666620Outcomes after Treatment of Metaplastic Versus Other Breast Cancer Subtypes
Q37364604Outcomes of her2-positive early-stage breast cancer in the trastuzumab era: a population-based study of Canadian patients
Q90044977Overexpression and alternative splicing of NF-YA in breast cancer
Q38578970Overview of Genetically Engineered Mouse Models of Breast Cancer Used in Translational Biology and Drug Development
Q36784065Overview of Genetically Engineered Mouse Models of Distinct Breast Cancer Subtypes
Q38888783Oxidative stress shapes breast cancer phenotype through chronic activation of ATM-dependent signaling
Q36147185PAM50 assay and the three-gene model for identifying the major and clinically relevant molecular subtypes of breast cancer
Q34433549PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers.
Q33883406PAM50 gene signatures and breast cancer prognosis with adjuvant anthracycline- and taxane-based chemotherapy: correlative analysis of C9741 (Alliance).
Q39189607PELO negatively regulates HER receptor signalling and metastasis
Q35610581PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer
Q91815720Pannexin1 Is Associated with Enhanced Epithelial-To-Mesenchymal Transition in Human Patient Breast Cancer Tissues and in Breast Cancer Cell Lines
Q55007506Panobinostat suppresses the mesenchymal phenotype in a novel claudin-low triple negative patient-derived breast cancer model.
Q36798949Paracrine Wnt signaling both promotes and inhibits human breast tumor growth
Q41379546PathAct: a novel method for pathway analysis using gene expression profiles
Q88959868Patient Similarity Networks for Precision Medicine
Q36903447Patient-derived breast tumor xenografts facilitating personalized cancer therapy
Q39057246Patient-derived xenograft (PDX) models in basic and translational breast cancer research.
Q27026531Patient-derived xenograft models of breast cancer and their predictive power
Q34037747Patient-derived xenografts, the cancer stem cell paradigm, and cancer pathobiology in the 21st century
Q36526547Patterns in target-directed breast cancer research
Q33731365Patterns of cell cycle checkpoint deregulation associated with intrinsic molecular subtypes of human breast cancer cells
Q42505998Pentraxin-3 is a PI3K signaling target that promotes stem cell-like traits in basal-like breast cancers.
Q64934294Personalized medicine in breast cancer: pharmacogenomics approaches.
Q43828188Personalized medicine in cancer: where are we today?
Q38196466Personalized therapy for breast cancer
Q36328010Pharmacogenomics: Biomarker-Directed Therapy for Bladder Cancer
Q39029043Pharmacological and immunological targeting of tumor mesenchymalization
Q48266858Phenotypic characteristics of colorectal cancer in BRCA1/2 mutation carriers.
Q35102562Pluripotent stem cell miRNAs and metastasis in invasive breast cancer
Q90312093Potential Role of MSC/Cancer Cell Fusion and EMT for Breast Cancer Stem Cell Formation
Q41134799Potential biomarkers of long-term benefit from single-agent trastuzumab or lapatinib in HER2-positive metastatic breast cancer
Q59812268Potential clinically useful prognostic biomarkers in triple-negative breast cancer: preliminary results of a retrospective analysis
Q33719480Potential tumor suppressor role for the c-Myb oncogene in luminal breast cancer.
Q100764047Practical classification of triple-negative breast cancer: intratumoral heterogeneity, mechanisms of drug resistance, and novel therapies
Q55010484Precision Medicine for Breast Cancer: The Paths to Truly Individualized Diagnosis and Treatment.
Q57105411Precision medicine based on tumorigenic signaling pathways for triple-negative breast cancer
Q47406496Precision medicine for urothelial bladder cancer: update on tumour genomics and immunotherapy
Q33809114Precision medicine in breast cancer: reality or utopia?
Q38790859Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor
Q37187379Predicting drug responsiveness in human cancers using genetically engineered mice.
Q34354538Predicting response and survival in chemotherapy-treated triple-negative breast cancer.
Q52714651Prediction of tumor mutation burden in breast cancer based on the expression of ER, PR, HER-2, and Ki-67.
Q38687963Predictive factors on outcomes in metaplastic breast cancer.
Q42454757Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures
Q48573972Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis
Q36449295Profiling the immune stromal interface in breast cancer and its potential for clinical impact
Q33916814Prognostic B-cell signatures using mRNA-seq in patients with subtype-specific breast and ovarian cancer
Q33646271Prognostic Evaluation of Epidermal Growth Factor Receptor (EGFR) Genotype and Phenotype Parameters in Triple-negative Breast Cancers
Q49868941Prognostic Significance of Low Claudin3 Expression in Luminal Breast Cancers
Q91739070Prognostic phenotypic classification for canine mammary tumors
Q64094448Prognostic role of Tif1γ expression and circulating tumor cells in patients with breast cancer
Q57298068Prognostic significance of p16 & p53 immunohistochemical expression in triple negative breast cancer
Q35180291Prognostic stromal gene signatures in breast cancer.
Q54519817Prognostic value of Ki-67 labeling index in patients with node-negative, triple-negative breast cancer.
Q37200485Prognostic value of the trichorhinophalangeal syndrome-1 (TRPS-1), a GATA family transcription factor, in early-stage breast cancer
Q33555787Prolactin cooperates with loss of p53 to promote claudin-low mammary carcinomas
Q39546203Prolonged mammosphere culture of MCF-7 cells induces an EMT and repression of the estrogen receptor by microRNAs
Q91291806Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer
Q38715089Promotion of invasion by mutant RAS is dependent on activation of the WASF3 metastasis promoter gene.
Q37620729Prostate apoptosis response-4 mediates TGF-β-induced epithelial-to-mesenchymal transition
Q93087257Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers
Q47261659Protein biomarkers for subtyping breast cancer and implications for future research.
Q36289925Protein expression changes during human triple negative breast cancer cell line progression to lymph node metastasis in a xenografted model in nude mice
Q58720701Proteomic analysis identifies highly expressed plasma membrane proteins for detection and therapeutic targeting of specific breast cancer subtypes
Q37696322Pubertal and adult windows of susceptibility to a high animal fat diet in Trp53-null mammary tumorigenesis
Q37685858Pubertal bisphenol A exposure alters murine mammary stem cell function leading to early neoplasia in regenerated glands
Q27340972Py2T murine breast cancer cells, a versatile model of TGFβ-induced EMT in vitro and in vivo
Q90749231Pyridine-Containing Macrocycles Display MMP-2/9 Inhibitory Activity and Distinct Effects on Migration and Invasion of 2D and 3D Breast Cancer Models
Q64112956Quantification of intrinsic subtype ambiguity in Luminal A breast cancer and its relationship to clinical outcomes
Q37395680RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation
Q36629504RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration.
Q35922859Race-associated biological differences among Luminal A breast tumors
Q24620175Radiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor type
Q37244377Radiation-induced gene signature predicts pathologic complete response to neoadjuvant chemotherapy in breast cancer patients
Q42446501Raf kinase inhibitory protein role in the molecular subtyping of breast cancer
Q34005143Rare breast cancer subtypes: histological, molecular, and clinical peculiarities
Q91891797Re-definition of claudin-low as a breast cancer phenotype
Q33618841Re-expression of miR-200c suppresses proliferation, colony formation and in vivo tumor growth of murine claudin-low mammary tumor cells.
Q55353691Recent Advances in the Treatment of Breast Cancer.
Q64100317Recent advances in understanding tumor stroma-mediated chemoresistance in breast cancer
Q38946859Recent progress with next-generation biomarkers in muscle-invasive bladder cancer.
Q92818881Refinement of breast cancer molecular classification by miRNA expression profiles
Q89870493Regulation and New Treatment Strategies in Breast Cancer
Q92316377Regulation of Immunity in Breast Cancer
Q38851695Regulation of stem cells-related signaling pathways in response to doxorubicin treatment in Hs578T triple-negative breast cancer cells.
Q28534173Regulation of the Epithelial-Mesenchymal Transition by Claudin-3 and Claudin-4
Q33995723Remodeling of purinergic receptor-mediated Ca2+ signaling as a consequence of EGF-induced epithelial-mesenchymal transition in breast cancer cells
Q36342182Reproductive history and breast cancer risk.
Q90203353Research-based PAM50 signature and long-term breast cancer survival
Q33659361Resistance to Taxanes in Triple-Negative Breast Cancer Associates with the Dynamics of a CD49f+ Tumor-Initiating Population
Q36383626Response and survival of breast cancer intrinsic subtypes following multi-agent neoadjuvant chemotherapy
Q90610564Response to Dabrafenib and Trametinib of a Patient with Metaplastic Breast Carcinoma Harboring a BRAF V600E Mutation
Q90152296Resveratrol Modifies Lipid Composition of Two Cancer Cell Lines
Q42378446Reverse phase protein array identification of triple-negative breast cancer subtypes and comparison with mRNA molecular subtypes
Q42282489Revisiting the impact of age and molecular subtype on overall survival after radiotherapy in breast cancer patients
Q54546191Risk factors for HR- and HER2-defined breast cancer in Slovenian postmenopausal women.
Q92749855Risk stratification of ER-positive breast cancer patients: A multi-institutional validation and outcome study of the Rochester Modified Magee algorithm (RoMMa) and prediction of an Oncotype DX® recurrence score <26
Q92155709Role of Claudin Proteins in Regulating Cancer Stem Cells and Chemoresistance-Potential Implication in Disease Prognosis and Therapy
Q37690034Role of HGF in epithelial-stromal cell interactions during progression from benign breast disease to ductal carcinoma in situ
Q35535296Role of IGF1R in Breast Cancer Subtypes, Stemness, and Lineage Differentiation
Q36677690Role of microRNAs in breast cancer
Q42511518Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression
Q36640358S100A8/A9 is associated with estrogen receptor loss in breast cancer
Q37447994SIK2 Restricts Autophagic Flux To Support Triple-Negative Breast Cancer Survival
Q64882163SMYD3 promotes the epithelial-mesenchymal transition in breast cancer.
Q34850997SOCS3-mediated regulation of inflammatory cytokines in PTEN and p53 inactivated triple negative breast cancer model
Q58709738SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis
Q91943174SRGN crosstalks with YAP to maintain chemoresistance and stemness in breast cancer cells by modulating HDAC2 expression
Q38988872STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer
Q37036337SWI/SNF chromatin-remodeling factor Smarcd3/Baf60c controls epithelial-mesenchymal transition by inducing Wnt5a signaling
Q36191982Screening and characterization of novel specific peptides targeting MDA-MB-231 claudin-low breast carcinoma by computer-aided phage display methodologies
Q44094790Second-line bevacizumab-containing therapy in patients with triple-negative breast cancer: subgroup analysis of the RIBBON-2 trial
Q91854833Selective Effects of Thioridazine on Self-Renewal of Basal-Like Breast Cancer Cells
Q35845827Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer.
Q38777346Sensitizing basal-like breast cancer to chemotherapy using nanoparticles conjugated with interference peptide.
Q47867377Sequential combination of docetaxel with a SHP-1 agonist enhanced suppression of p-STAT3 signaling and apoptosis in triple negative breast cancer cells
Q38398043Shotgun proteomics of archival triple-negative breast cancer samples
Q45058372Should we treat minimal breast cancer lesions?
Q35213019Signaling mechanisms of the epithelial-mesenchymal transition
Q35000293Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway
Q89985480Silver nanoparticles selectively treat triple-negative breast cancer cells without affecting non-malignant breast epithelial cells in vitro and in vivo
Q33889288Simultaneous siRNA targeting of Src and downstream signaling molecules inhibit tumor formation and metastasis of a human model breast cancer cell line
Q98718297Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer
Q58799648Somatic loss of WWOX is associated with TP53 perturbation in basal-like breast cancer
Q27320285Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells
Q52575440Specific breast cancer prognosis-subtype distinctions based on DNA methylation patterns.
Q90114938Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain
Q91713420Sphingosine Kinase 1 in Breast Cancer-A New Molecular Marker and a Therapy Target
Q36436933Splicing program of human MENA produces a previously undescribed isoform associated with invasive, mesenchymal-like breast tumors
Q31132069Spontaneous epithelial-mesenchymal transition and resistance to HER-2-targeted therapies in HER-2-positive luminal breast cancer
Q34774884Standard of care and promising new agents for triple negative metastatic breast cancer
Q47151800Statistical significance for hierarchical clustering.
Q42972655Stratifying triple-negative breast cancer: which definition(s) to use?
Q47768899Suppression of MAPK signaling in BRAF-activated PTEN-deficient melanoma by blocking β-catenin signaling in cancer-associated fibroblasts
Q21135222Suppression of breast tumor growth and metastasis by an engineered transcription factor
Q36353410Surveillance of spontaneous breast cancer metastasis by TRAIL-expressing CD34⁺ cells in a xenograft model
Q64325058Survival Study of Triple-Negative and Non-Triple-Negative Breast Cancer in a Brazilian Cohort
Q24624489Synthesis of site-specific antibody-drug conjugates using unnatural amino acids
Q34049023Systematic analysis of metastasis-associated genes identifies miR-17-5p as a metastatic suppressor of basal-like breast cancer.
Q37331472Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer
Q34576377Systems biology and genomics of breast cancer
Q36145430TBCRC 001: randomized phase II study of cetuximab in combination with carboplatin in stage IV triple-negative breast cancer
Q33954557TBCRC 018: phase II study of iniparib in combination with irinotecan to treat progressive triple negative breast cancer brain metastases.
Q27853147TBCRC009: A Multicenter Phase II Clinical Trial of Platinum Monotherapy With Biomarker Assessment in Metastatic Triple-Negative Breast Cancer
Q61804904TBL1 is required for the mesenchymal phenotype of transformed breast cancer cells
Q42512528TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer
Q39368430TIP60 inhibits metastasis by ablating DNMT1-SNAIL2-driven epithelial-mesenchymal transition program.
Q93075081TNBC Challenge: Oligonucleotide Aptamers for New Imaging and Therapy Modalities
Q36148592TP53 mutation, epithelial-mesenchymal transition, and stemlike features in breast cancer subtypes
Q42510422TRPC1 is a differential regulator of hypoxia-mediated events and Akt signalling in PTEN-deficient breast cancer cells
Q37697038TRPC1-STIM1 activation modulates transforming growth factor β-induced epithelial-to-mesenchymal transition
Q99207626TRPV6 calcium channel directs homeostasis of the mammary epithelial sheets and controls epithelial mesenchymal transition
Q36476219Targeted Pten deletion plus p53-R270H mutation in mouse mammary epithelium induces aggressive claudin-low and basal-like breast cancer
Q36144913Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer
Q37190825Targeted therapy for breast cancer prevention
Q38009760Targeted therapy for triple-negative breast cancer: where are we?
Q39456790Targeting Androgen/Estrogen Receptors Crosstalk in Cancer
Q57107358Targeting Breast Cancer Stem Cells to Overcome Treatment Resistance
Q38209586Targeting CD73 and downstream adenosine receptor signaling in triple-negative breast cancer
Q33631501Targeting Met and Notch in the Lfng-deficient, Met-amplified triple-negative breast cancer.
Q35174128Targeting a cell state common to triple-negative breast cancers
Q47385983Targeting bromodomain and extraterminal proteins in breast cancer
Q38836110Targeting the Breast Cancer Kinome
Q39339106Targeting the Molecular Subtypes of Triple Negative Breast Cancer: Understanding the Diversity to Progress the Field
Q36790763Targeting the WASF3-CYFIP1 Complex Using Stapled Peptides Suppresses Cancer Cell Invasion
Q42364449Targeting the androgen receptor in triple-negative breast cancer: current perspectives
Q36245380Targeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat
Q38295108The 2014 Society of Surgical Oncology Susan G. Komen for the Cure Symposium: triple-negative breast cancer
Q39071403The Cellular Origin and Evolution of Breast Cancer
Q35687706The Clinicopathologic and Prognostic Value of Altered Chromosome 17 Centromere Copy Number in HER2 Fish Equivocal Breast Carcinomas
Q91715241The Detection and Morphological Analysis of Circulating Tumor and Host Cells in Breast Cancer Xenograft Models
Q30978083The Discovery of Novel Biomarkers Improves Breast Cancer Intrinsic Subtype Prediction and Reconciles the Labels in the METABRIC Data Set.
Q42516196The Epithelial-to-Mesenchymal Transition in Breast Cancer: Focus on Basal-Like Carcinomas
Q95267155The Expression and Prognostic Significance of Claudin-8 and Androgen Receptor in Breast Cancer
Q34495216The FGF/FGFR axis as a therapeutic target in breast cancer
Q42371555The H3K27me3-demethylase KDM6A is suppressed in breast cancer stem-like cells, and enables the resolution of bivalency during the mesenchymal-epithelial transition
Q89286757The Kraken Wakes: induced EMT as a driver of tumour aggression and poor outcome
Q92859442The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor
Q90080264The Molecular Mechanism of Epithelial-Mesenchymal Transition for Breast Carcinogenesis
Q64066030The New Synthetic Serum-Free Medium OptiPASS Promotes High Proliferation and Drug Efficacy Prediction on Spheroids from MDA-MB-231 and SUM1315 Triple-Negative Breast Cancer Cell Lines
Q36947310The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells
Q57817312The SCRIB Paralog LANO/LRRC1 Regulates Breast Cancer Stem Cell Fate through WNT/β-Catenin Signaling
Q39453298The Spectrum of Triple-Negative Breast Disease: High- and Low-Grade Lesions
Q36109766The T box transcription factor TBX2 promotes epithelial-mesenchymal transition and invasion of normal and malignant breast epithelial cells
Q36580632The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl
Q38890318The Tyrosine Kinome Dictates Breast Cancer Heterogeneity and Therapeutic Responsiveness
Q38757069The WASF3-NCKAP1-CYFIP1 Complex Is Essential for Breast Cancer Metastasis
Q47372771The ability of PAM50 risk of recurrence score to predict 10-year distant recurrence in hormone receptor-positive postmenopausal women with special histological subtypes
Q34086632The breast cancer genome--a key for better oncology
Q27317001The calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin.
Q36336601The changing role of ER in endocrine resistance
Q47167746The crossroads of breast cancer progression: insights into the modulation of major signaling pathways
Q47236781The depalmitoylase APT1 directs the asymmetric partitioning of Notch and Wnt signaling during cell division
Q36507087The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1
Q36903188The estrogen-regulated anterior gradient 2 (AGR2) protein in breast cancer: a potential drug target and biomarker
Q44770771The exon 38-containing ARHGEF11 splice isoform is differentially expressed and is required for migration and growth in invasive breast cancer cells
Q34472128The expression and clinical significance of ribophorin II (RPN2) in human breast cancer
Q26775232The fate of chemoresistance in triple negative breast cancer (TNBC)
Q36098052The forkhead box transcription factor FOXC1 promotes breast cancer invasion by inducing matrix metalloprotease 7 (MMP7) expression.
Q36924454The gene expression landscape of breast cancer is shaped by tumor protein p53 status and epithelial-mesenchymal transition
Q37691054The genomic map of breast cancer: which roads lead to better targeted therapies?
Q26740373The hedgehog pathway in triple-negative breast cancer
Q103806134The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer
Q33660069The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy.
Q38208007The involvement of JAK-STAT3 in cell motility, invasion, and metastasis
Q35032523The landscape of candidate driver genes differs between male and female breast cancer
Q34258373The latest progress in research on triple negative breast cancer (TNBC): risk factors, possible therapeutic targets and prognostic markers
Q38026421The malignant social network: cell-cell adhesion and communication in cancer stem cells
Q34396558The mammary cellular hierarchy and breast cancer.
Q36525461The origin of breast tumor heterogeneity
Q91239720The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20
Q37376414The prognostic and predictive value of the lymphocyte to monocyte ratio in luminal-type breast cancer patients treated with CEF chemotherapy
Q40714796The prognostic impact of age in different molecular subtypes of breast cancer
Q48002827The prognostic role of claudins in head and neck squamous cell carcinomas
Q46842412The prognostic significance of combined androgen receptor, E-Cadherin, Ki67 and CK5/6 expression in patients with triple negative breast cancer
Q27005952The promise of multi-omics and clinical data integration to identify and target personalized healthcare approaches in autism spectrum disorders
Q27320721The proteomic landscape of triple-negative breast cancer
Q35657873The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium
Q38483125The relevance of EMT in breast cancer metastasis: Correlation or causality?
Q37118399The relevance of the TGF-β Paradox to EMT-MET programs
Q38927656The role of claudins in cancer metastasis
Q37123982The role of epithelial-mesenchymal transition programming in invasion and metastasis: a clinical perspective
Q35122705The role of lipolysis stimulated lipoprotein receptor in breast cancer and directing breast cancer cell behavior
Q96222254The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer
Q90484944The therapeutic response of ER+/HER2- breast cancers differs according to the molecular Basal or Luminal subtype
Q28743642The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer
Q55174811The versatile nature of miR-9/9* in human cancer.
Q47638243Therapeutic Implications of the Molecular and Immune Landscape of Triple-Negative Breast Cancer.
Q38084287Therapeutic targets in triple negative breast cancer
Q38424397Therapies for triple negative breast cancer
Q58763424TiHo-0906: a new feline mammary cancer cell line with molecular, morphological, and immunocytological characteristics of epithelial to mesenchymal transition
Q61811129Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk
Q36343793Tight junction proteins claudin-3 and claudin-4 control tumor growth and metastases
Q37118065Tight junction proteins: from barrier to tumorigenesis.
Q37989074Topoisomerase 2 alpha: a real predictor of anthracycline efficacy?
Q26829478Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer
Q39242906Transcription factors link mouse WAP-T mammary tumors with human breast cancer
Q64068503Transcriptional factor six2 promotes the competitive endogenous RNA network between CYP4Z1 and pseudogene CYP4Z2P responsible for maintaining the stemness of breast cancer cells
Q33742688Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts
Q47134924Transforming Growth Factor-beta Regulation of Ephrin Type-A Receptor 4 Signaling in Breast Cancer Cellular Migration
Q36081908Transgenic IGF-IR overexpression induces mammary tumors with basal-like characteristics, whereas IGF-IR-independent mammary tumors express a claudin-low gene signature
Q37711615Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification
Q35934478Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance.
Q47927802Treg depletion potentiates checkpoint inhibition in claudin-low breast cancer
Q64097271Triple Negative Breast Cancer Profile, from Gene to microRNA, in Relation to Ethnicity
Q38007037Triple negative breast cancer: a brief review of its characteristics and treatment options
Q26783122Triple negative breast cancer: looking for the missing link between biology and treatments
Q42498742Triple-Negative Breast Cancer: A Comprehensive Study of Clinical, Histomorphological, and Immunohistochemical Features in Indian Patients
Q90040642Triple-Negative Breast Cancer: Current Understanding and Future Therapeutic Breakthrough Targeting Cancer Stemness
Q57115890Triple-negative breast cancer and the potential for targeted therapy
Q35549438Triple-negative breast cancer with brain metastases: a comparison between basal-like and non-basal-like biological subtypes.
Q35692146Triple-negative breast cancer: adjuvant therapeutic options
Q33915057Triple-negative breast cancer: the importance of molecular and histologic subtyping, and recognition of low-grade variants
Q36940085Triple-negative breast cancer: treatment challenges and solutions
Q34269541Triple-negative vimentin-positive heterogeneous feline mammary carcinomas as a potential comparative model for breast cancer
Q36471435Tumor Cell-Derived Periostin Regulates Cytokines That Maintain Breast Cancer Stem Cells.
Q47146956Tumor Heterogeneity in Breast Cancer
Q21296683Tumor angiogenesis: pericytes and maturation are not to be ignored
Q36411711Tumor characteristics and the clinical outcome of invasive lobular carcinoma compared to infiltrating ductal carcinoma in a Chinese population
Q35624103Tumor intrinsic subtype is reflected in cancer-adjacent tissue.
Q90748016Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers
Q35575679Tumor twitter: cellular communication in the breast cancer stem cell niche
Q36984367Tumor-Associated Macrophage-Mediated Targeted Therapy of Triple-Negative Breast Cancer.
Q45073569Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
Q49494144Tumor-infiltrating lymphocytes are associated with β-catenin overexpression in breast cancer
Q58799845Tumor-stroma interactions differentially alter drug sensitivity based on the origin of stromal cells
Q36557847Tumour-infiltrating FOXP3(+) lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer.
Q33613560Tumour-initiating capacity is independent of epithelial-mesenchymal transition status in breast cancer cell lines
Q84594497Two possible mechanisms of epithelial to mesenchymal transition in invasive ductal breast cancer
Q47614178Ubiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein.
Q43407097Uncovering the molecular secrets of inflammatory breast cancer biology: an integrated analysis of three distinct affymetrix gene expression datasets
Q26773472Understanding the role of the kynurenine pathway in human breast cancer immunobiology
Q52587869Update on the Treatment of Early-Stage Triple-Negative Breast Cancer.
Q36311616Update on triple-negative breast cancer: prognosis and management strategies
Q47193038Using gene expression data to direct breast cancer therapy: evidence from a preclinical trial
Q40123917Variability in DNA Repair Capacity Levels among Molecular Breast Cancer Subtypes: Triple Negative Breast Cancer Shows Lowest Repair
Q92539420Variational Autoencoders for Cancer Data Integration: Design Principles and Computational Practice
Q35000353Vascular endothelial growth factor C promotes breast cancer progression via a novel antioxidant mechanism that involves regulation of superoxide dismutase 3.
Q34034767Vimentin DNA methylation predicts survival in breast cancer
Q37016288Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.
Q37124053WASF3 provides the conduit to facilitate invasion and metastasis in breast cancer cells through HER2/HER3 signaling
Q37720633WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells
Q91948227WITHDRAWN: Tanshinone IIA-mediated inhibition on miR-125b/STARD13 axis attenuates the stemness and enhances adriamycin sensitivity of breast cancer cells
Q91297679WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer
Q37721627WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel
Q50910046Whole-Exome Sequencing of Metaplastic Breast Carcinoma Indicates Monoclonality with Associated Ductal Carcinoma Component.
Q35883071Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation
Q39214992Wnt signaling in triple-negative breast cancer.
Q38529063ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types
Q47588078ZEB1-repressed microRNAs inhibit autocrine signaling that promotes vascular mimicry of breast cancer cells
Q92060237ZGRF1 Is Associated with Poor Prognosis in Triple-Negative Breast Cancer and Promotes Cancer Stemness Based on Bioinformatics
Q34869169c-Jun N-terminal kinase 2 (JNK2) enhances cell migration through epidermal growth factor substrate 8 (EPS8).
Q35828457c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression
Q39093109c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer.
Q34880881eEF2K--a new target in breast cancers with combined inactivation of p53 and PTEN
Q38778447miR-141-Mediated Regulation of Brain Metastasis From Breast Cancer.
Q42493425miR-221/222 targeting of trichorhinophalangeal 1 (TRPS1) promotes epithelial-to-mesenchymal transition in breast cancer
Q28115315miR-221/222 targets adiponectin receptor 1 to promote the epithelial-to-mesenchymal transition in breast cancer
Q36902949miRNA expression profiling of 51 human breast cancer cell lines reveals subtype and driver mutation-specific miRNAs
Q41252362microRNA-143/145 loss induces Ras signaling to promote aggressive Pten-deficient basal-like breast cancer
Q33739297p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells
Q42500912p53 deficiency induces cancer stem cell pool expansion in a mouse model of triple-negative breast tumors
Q34298024p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition
Q61805409pAKT pathway activation is associated with mutations and good prognosis in luminal breast cancer in contrast to p-mTOR pathway activation
Q36070381ΔNp63α Promotes Breast Cancer Cell Motility through the Selective Activation of Components of the Epithelial-to-Mesenchymal Transition Program
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