scholarly article | Q13442814 |
P2093 | author name string | William P Schiemann | |
Jenny G Parvani | |||
Chevaun D Morrison | |||
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TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch | Q39903519 | ||
Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells | Q39939949 | ||
Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas | Q39971722 | ||
Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer | Q40079491 | ||
Hypoxia/reoxygenation: a dynamic regulator of lysyl oxidase-facilitated breast cancer migration | Q40096756 | ||
Human epithelial basal cells are cells of origin of prostate cancer, independent of CD133 status. | Q42506512 | ||
Epithelial-mesenchymal transition induced by growth suppressor p12CDK2-AP1 promotes tumor cell local invasion but suppresses distant colony growth | Q43225336 | ||
A phase II trial of imatinib mesylate monotherapy in patients with metastatic breast cancer. | Q43487632 | ||
Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity | Q45405811 | ||
Imaging transforming growth factor-beta signaling dynamics and therapeutic response in breast cancer bone metastasis. | Q52594636 | ||
Differential regulation of the two RhoA-specific GEF isoforms Net1/Net1A by TGF-β and miR-24: role in epithelial-to-mesenchymal transition. | Q52617207 | ||
E-cadherin is a ligand for integrin α2β1 | Q58057935 | ||
High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-beta1 | Q79643431 | ||
Src phosphorylates Tyr284 in TGF-beta type II receptor and regulates TGF-beta stimulation of p38 MAPK during breast cancer cell proliferation and invasion | Q80171744 | ||
To differentiate or not--routes towards metastasis | Q84106913 | ||
Cancer stem cells | Q84976114 | ||
Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling | Q24298472 | ||
The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner | Q24308947 | ||
A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression | Q24314451 | ||
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing | Q24321530 | ||
Epithelial-mesenchymal transition-derived cells exhibit multilineage differentiation potential similar to mesenchymal stem cells | Q24599620 | ||
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche | Q24606366 | ||
miR-21 and miR-31 Converge on TIAM1 to Regulate Migration and Invasion of Colon Carcinoma Cells | Q24613084 | ||
Matrix crosslinking forces tumor progression by enhancing integrin signaling | Q24646370 | ||
MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA | Q24648090 | ||
The epithelial-mesenchymal transition generates cells with properties of stem cells | Q24650786 | ||
The basics of epithelial-mesenchymal transition | Q24652992 | ||
The miR-200 and miR-221/222 microRNA families: opposing effects on epithelial identity | Q27010233 | ||
An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype | Q27339197 | ||
Epithelial-mesenchymal transitions in development and disease | Q27860630 | ||
Tensional homeostasis and the malignant phenotype | Q27860932 | ||
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 | Q27861068 | ||
Alternative isoform regulation in human tissue transcriptomes | Q27861118 | ||
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer | Q28131829 | ||
miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis | Q28236600 | ||
RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasis | Q28236828 | ||
Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility | Q28261746 | ||
TGFbeta in Cancer | Q28288866 | ||
Molecular definition of breast tumor heterogeneity | Q28292256 | ||
TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition | Q28512991 | ||
Type II Transforming Growth Factor-β Receptor Recycling Is Dependent upon the Clathrin Adaptor Protein Dab2 | Q28588905 | ||
Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics | Q28751743 | ||
SMAD proteins control DROSHA-mediated microRNA maturation | Q28941771 | ||
Integrins in cancer: biological implications and therapeutic opportunities | Q29614536 | ||
Reversibility of epithelial-mesenchymal transition (EMT) induced in breast cancer cells by activation of urokinase receptor-dependent cell signaling | Q37371663 | ||
X-linked inhibitor of apoptosis protein and its E3 ligase activity promote transforming growth factor-{beta}-mediated nuclear factor-{kappa}B activation during breast cancer progression | Q37372003 | ||
beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium | Q37460431 | ||
Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasis | Q37467183 | ||
MicroRNAs: novel regulators in the hallmarks of human cancer | Q37493501 | ||
Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer. | Q37721840 | ||
Endoplasmic reticulum protein 29 (ERp29): An emerging role in cancer | Q37797638 | ||
Cancer cells in epithelial-to-mesenchymal transition and tumor-propagating-cancer stem cells: distinct, overlapping or same populations | Q37885165 | ||
Mechanism of the mesenchymal-epithelial transition and its relationship with metastatic tumor formation | Q37917310 | ||
MicroRNAs: critical regulators of epithelial to mesenchymal (EMT) and mesenchymal to epithelial transition (MET) in cancer progression | Q37970478 | ||
Induction of epithelial-mesenchymal transition by transforming growth factor β. | Q38006771 | ||
TGF-β-induced epithelial-mesenchymal transition: a link between cancer and inflammation | Q38012975 | ||
Regulation of EMT by TGFβ in cancer. | Q38019712 | ||
Endoplasmic reticulum protein 29 regulates epithelial cell integrity during the mesenchymal-epithelial transition in breast cancer cells | Q39356840 | ||
Suppression of the epithelial-mesenchymal transition by Grainyhead-like-2. | Q39387840 | ||
TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP. | Q39451094 | ||
The BMP2/7 heterodimer inhibits the human breast cancer stem cell subpopulation and bone metastases formation | Q39458532 | ||
Targets of the tumor suppressor miR-200 in regulation of the epithelial-mesenchymal transition in cancer. | Q39460209 | ||
TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer. | Q39532727 | ||
Altered TGF-β signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis. | Q39595827 | ||
Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors | Q39646992 | ||
An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition | Q39667327 | ||
Exon-based clustering of murine breast tumor transcriptomes reveals alternative exons whose expression is associated with metastasis | Q39747555 | ||
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors | Q29615393 | ||
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia | Q29618875 | ||
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer | Q29619481 | ||
Generation of breast cancer stem cells through epithelial-mesenchymal transition | Q29619717 | ||
Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features | Q29620020 | ||
uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells | Q30443804 | ||
Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer. | Q30502431 | ||
TGF-beta receptor 2 downregulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: a retrospective study | Q33293871 | ||
p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity. | Q33553472 | ||
Activated Abl kinase inhibits oncogenic transforming growth factor-beta signaling and tumorigenesis in mammary tumors | Q33613286 | ||
ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration | Q33705264 | ||
PGE2 receptor EP2 mediates the antagonistic effect of COX-2 on TGF-beta signaling during mammary tumorigenesis | Q33752909 | ||
Mechanisms of disease: epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression? | Q33755906 | ||
Role of integrins in cancer: survey of expression patterns | Q33774941 | ||
Mechanisms of the epithelial-mesenchymal transition by TGF-beta | Q33804105 | ||
Roles for the type III TGF-beta receptor in human cancer | Q33872593 | ||
miR-10b targets Tiam1: implications for Rac activation and carcinoma migration | Q33966873 | ||
Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha | Q34065396 | ||
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes | Q34100400 | ||
The organization of tight junctions in epithelia: implications for mammary gland biology and breast tumorigenesis | Q34103481 | ||
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts | Q34125363 | ||
Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation | Q34174349 | ||
Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas | Q34197948 | ||
Non-Smad TGF-beta signals | Q34443708 | ||
Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs | Q34608570 | ||
Identification of a stem-like cell population by exposing metastatic breast cancer cell lines to repetitive cycles of hypoxia and reoxygenation | Q34613520 | ||
Homeoprotein Six1 Increases TGF-β Type I Receptor and Converts TGF-β Signaling from Suppressive to Supportive for Tumor Growth | Q34768886 | ||
Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks | Q34781947 | ||
p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. | Q34787898 | ||
Transforming growth factor-β and the hallmarks of cancer | Q34789300 | ||
Lysyl oxidase contributes to mechanotransduction-mediated regulation of transforming growth factor-β signaling in breast cancer cells | Q34887552 | ||
The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis | Q34933986 | ||
An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition | Q34977307 | ||
TGFbeta/TNF(alpha)-mediated epithelial-mesenchymal transition generates breast cancer stem cells with a claudin-low phenotype | Q35085542 | ||
Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells | Q35134466 | ||
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization | Q35204515 | ||
Epithelial-Mesenchymal Transition in tumor microenvironment | Q35230386 | ||
Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell properties | Q35243673 | ||
Beta3 integrin and Src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells | Q35605733 | ||
Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators. | Q35778924 | ||
Matrix rigidity regulates a switch between TGF-β1-induced apoptosis and epithelial-mesenchymal transition | Q35790882 | ||
The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer. | Q35928749 | ||
Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells | Q36006612 | ||
Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment | Q36215812 | ||
A phase II study of imatinib mesylate and capecitabine in metastatic breast cancer: Southwest Oncology Group Study 0338 | Q36435548 | ||
Differential cadherin expression: potential markers for epithelial to mesenchymal transformation during tumor progression | Q36847939 | ||
Mesenchymal to epithelial transition in development and disease. | Q36857740 | ||
Transforming growth factor-beta and microRNA:mRNA regulatory networks in epithelial plasticity | Q36857841 | ||
Treatment for chronic myelogenous leukemia: the long road to imatinib | Q36900105 | ||
Applying the discovery of the Philadelphia chromosome | Q36900109 | ||
Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton. | Q36922699 | ||
Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-beta through a PGE2-dependent mechanisms | Q36959011 | ||
The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells | Q37040558 | ||
TGF-β stimulates Pyk2 expression as part of an epithelial-mesenchymal transition program required for metastatic outgrowth of breast cancer | Q37040574 | ||
Grb2 binding to Tyr284 in TbetaR-II is essential for mammary tumor growth and metastasis stimulated by TGF-beta | Q37041510 | ||
Altered TAB1:I kappaB kinase interaction promotes transforming growth factor beta-mediated nuclear factor-kappaB activation during breast cancer progression | Q37041538 | ||
Noncanonical TGF-β signaling during mammary tumorigenesis | Q37044600 | ||
Role of TGF-β and the tumor microenvironment during mammary tumorigenesis | Q37044604 | ||
Deconstructing the mechanisms and consequences of TGF-β-induced EMT during cancer progression | Q37044614 | ||
TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta | Q37052635 | ||
Three-dimensional context regulation of metastasis | Q37111021 | ||
Cancer-associated transforming growth factor beta type II receptor gene mutant causes activation of bone morphogenic protein-Smads and invasive phenotype | Q37155797 | ||
The TGF-beta paradox in human cancer: an update | Q37261631 | ||
Role of TGF-beta in the tumor stroma | Q37264582 | ||
MicroRNAs as regulators of epithelial-mesenchymal transition. | Q37300965 | ||
Imatinib mesylate (Gleevec) in advanced breast cancer-expressing C-Kit or PDGFR-beta: clinical activity and biological correlations | Q37326191 | ||
The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling | Q37328463 | ||
Roles of TGF-beta family signaling in stem cell renewal and differentiation | Q37359959 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 30-40 | |
P577 | publication date | 2013-03-05 | |
P1433 | published in | Cancer Letters | Q326372 |
P1476 | title | The relevance of the TGF-β Paradox to EMT-MET programs | |
P478 | volume | 341 |
Q38693858 | A kinetic model of multiple phenotypic states for breast cancer cells. |
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Q64976524 | Cytokines and radiation-induced pulmonary injuries. |
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