Paralogous outer membrane proteins mediate uptake of different forms of iron and synergistically govern virulence in Francisella tularensis tularensis

scientific article

Paralogous outer membrane proteins mediate uptake of different forms of iron and synergistically govern virulence in Francisella tularensis tularensis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M112.371856
P932PMC publication ID3408188
P698PubMed publication ID22661710

P2093author name stringRichard Johnson
Girija Ramakrishnan
Bhaswati Sen
P2860cites workThe complete genome sequence of Francisella tularensis, the causative agent of tularemiaQ22122045
PATRIC: the comprehensive bacterial bioinformatics resource with a focus on human pathogenic speciesQ24609706
A Hidden Markov Model method, capable of predicting and discriminating beta-barrel outer membrane proteinsQ24803433
Evasion of IFN-γ signaling by Francisella novicida is dependent upon Francisella outer membrane protein CQ28477609
Bacterial iron homeostasisQ29615095
Overcoming expression and purification problems of RhoGDI using a family of "parallel" expression vectorsQ29617999
Legionella pneumophila LbtU acts as a novel, TonB-independent receptor for the legiobactin siderophoreQ30155870
PRED-TMBB: a web server for predicting the topology of beta-barrel outer membrane proteinsQ30163988
Intracellular fate of Francisella tularensis within arthropod-derived cellsQ39883439
An attenuated strain of the facultative intracellular bacterium Francisella tularensis can escape the phagosome of monocytic cellsQ39913009
Characterization of the ferrous iron uptake system of Escherichia coliQ39937148
MglA and Igl proteins contribute to the modulation of Francisella tularensis live vaccine strain-containing phagosomes in murine macrophagesQ39982923
Growth of Francisella spp. in rodent macrophages.Q40151869
Early pathogenesis of infection in the liver with the facultative intracellular bacteria Listeria monocytogenes, Francisella tularensis, and Salmonella typhimurium involves lysis of infected hepatocytes by leukocytesQ40152524
Characterization of fig operon mutants of Francisella novicida U112.Q42600585
The fslE homolog, FTL_0439 (fupA/B), mediates siderophore-dependent iron uptake in Francisella tularensis LVS.Q30432826
Characterization of the siderophore of Francisella tularensis and role of fslA in siderophore productionQ30440483
fslE is necessary for siderophore-mediated iron acquisition in Francisella tularensis Schu S4Q30440726
Modulation of iron homeostasis in macrophages by bacterial intracellular pathogensQ33534484
Gallium disrupts iron uptake by intracellular and extracellular Francisella strains and exhibits therapeutic efficacy in a murine pulmonary infection modelQ33558904
Molecular bases of proliferation of Francisella tularensis in arthropod vectorsQ33581030
Molecular complexity orchestrates modulation of phagosome biogenesis and escape to the cytosol of macrophages by Francisella tularensisQ33581036
EVALUATION OF LIVE TULAREMIA VACCINE PREPARED IN A CHEMICALLY DEFINED MEDIUM.Q33696706
Iron metabolism in pathogenic bacteria.Q33920195
Macrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence.Q34018936
TonB-dependent transporters: regulation, structure, and function.Q34112189
Virulent and avirulent strains of Francisella tularensis prevent acidification and maturation of their phagosomes and escape into the cytoplasm in human macrophagesQ34145815
A mutant of Francisella tularensis strain SCHU S4 lacking the ability to express a 58-kilodalton protein is attenuated for virulence and is an effective live vaccineQ34194818
Tularemia: history, epidemiology, pathogen physiology, and clinical manifestationsQ34613846
Identification of Francisella tularensis genes affected by iron limitationQ34721354
Survival and growth of Francisella tularensis in Acanthamoeba castellaniiQ34877012
Acquisition of siderophores in gram-negative bacteria.Q35058516
Common ancestry and novel genetic traits of Francisella novicida-like isolates from North America and Australia as revealed by comparative genomic analysesQ35139081
Bacterial outer membrane channel for divalent metal ion acquisitionQ35216958
Growth of Francisella tularensis LVS in macrophages: the acidic intracellular compartment provides essential iron required for growthQ35403392
Characterization of Francisella tularensis outer membrane proteinsQ35634834
In vivo negative selection screen identifies genes required for Francisella virulenceQ35699734
Effect of exogenous reductant on growth and iron mobilization from ferrihydrite by the Pseudomonas mendocina ymp strainQ35869721
Genome-wide identification of Francisella tularensis virulence determinantsQ35913441
The major facilitator superfamily-type protein LbtC promotes the utilization of the legiobactin siderophore by Legionella pneumophilaQ35959585
Molecular epidemiology, evolution, and ecology of FrancisellaQ36792208
Innate and adaptive immunity to FrancisellaQ36806170
Influence of genetic background on host resistance to experimental murine tularemiaQ36998287
Reintroduction of two deleted virulence loci restores full virulence to the live vaccine strain of Francisella tularensisQ37274784
The 58-kilodalton major virulence factor of Francisella tularensis is required for efficient utilization of ironQ37355882
CLASSIFICATION OF MICROORGANISMS BY ANALYSIS OF CHEMICAL COMPOSITION. I. FEASIBILITY OF UTILIZING GAS CHROMATOGRAPHY.Q37436376
Working toward the future: insights into Francisella tularensis pathogenesis and vaccine developmentQ37451520
Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains.Q38606114
Identification of differentially regulated francisella tularensis genes by use of a newly developed Tn5-based transposon delivery system.Q38607194
P433issue30
P407language of work or nameEnglishQ1860
P921main subjectmembrane proteinQ423042
Francisella tularensisQ1003460
P304page(s)25191-25202
P577publication date2012-06-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleParalogous outer membrane proteins mediate uptake of different forms of iron and synergistically govern virulence in Francisella tularensis tularensis
P478volume287

Reverse relations

cites work (P2860)
Q28082373An update on iron acquisition by Legionella pneumophila: new pathways for siderophore uptake and ferric iron reduction
Q36106837Comparative Transcriptional Analyses of Francisella tularensis and Francisella novicida
Q30277068Components of the type six secretion system are substrates of Francisella tularensis Schu S4 DsbA-like FipB protein
Q28675489FeoB-mediated uptake of iron by Francisella tularensis
Q30406080FipB, an essential virulence factor of Francisella tularensis subsp. tularensis, has dual roles in disulfide bond formation
Q36101152FmvB: A Francisella tularensis Magnesium-Responsive Outer Membrane Protein that Plays a Role in Virulence
Q92521763Francisella tularensis: FupA mutation contributes to fluoroquinolone resistance by increasing vesicle secretion and biofilm formation
Q26771366From the Outside-In: The Francisella tularensis Envelope and Virulence
Q36439089Gallium Potentiates the Antibacterial Effect of Gentamicin against Francisella tularensis
Q30353186Iron and Virulence in Francisella tularensis.
Q35574562Mechanisms of heme utilization by Francisella tularensis
Q34068402Mitochondrial ROS potentiates indirect activation of the AIM2 inflammasome.
Q38052945Proteins involved in Francisella tularensis survival and replication inside macrophages
Q57139247Structural and functional studies of the metalloregulator Fur identify a promoter-binding mechanism and its role in virulence
Q30408382The FupA/B protein uniquely facilitates transport of ferrous iron and siderophore-associated ferric iron across the outer membrane of Francisella tularensis live vaccine strain
Q34044097The Yersinia pestis siderophore, yersiniabactin, and the ZnuABC system both contribute to zinc acquisition and the development of lethal septicaemic plague in mice.
Q45091061The ferrous iron transporter FtrABCD is required for the virulence of Brucella abortus 2308 in mice
Q30413938The reduced genome of the Francisella tularensis live vaccine strain (LVS) encodes two iron acquisition systems essential for optimal growth and virulence
Q28468502Transcriptome Analysis of the Intracellular Facultative Pathogen Piscirickettsia salmonis: Expression of Putative Groups of Genes Associated with Virulence and Iron Metabolism
Q30277263Two parallel pathways for ferric and ferrous iron acquisition support growth and virulence of the intracellular pathogen Francisella tularensis Schu S4
Q45072111Zinc acquisition mechanisms differ between environmental and virulent Francisella species.

Search more.