review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1007/S00018-008-8122-2 |
P698 | PubMed publication ID | 18563293 |
P2093 | author name string | T E Smithgall | |
S Banu Ozkan | |||
I Bahar | |||
J R Engen | |||
M A Meyn | |||
T E Wales | |||
J M Hochrein | |||
P433 | issue | 19 | |
P304 | page(s) | 3058-3073 | |
P577 | publication date | 2008-10-01 | |
P1433 | published in | Cellular and Molecular Life Sciences | Q5058352 |
P1476 | title | Structure and dynamic regulation of Src-family kinases | |
P478 | volume | 65 |
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Q43113518 | A selective NMR probe to monitor the conformational transition from inactive to active kinase |
Q53275233 | Actin filament associated protein mediates c-Src related SRE/AP-1 transcriptional activation. |
Q27675080 | Active site profiling reveals coupling between domains in SRC-family kinases |
Q37308513 | Age-related changes in lck-Vav signaling pathways in mouse CD4 T cells |
Q39025588 | Alcohol-dependent molecular adaptations of the NMDA receptor system |
Q50878641 | Allosteric Modulation of Src Family Kinases with ATP-Competitive Inhibitors. |
Q31000736 | An unexpected role for the clock protein timeless in developmental apoptosis |
Q31036445 | B cell activation triggered by the formation of the small receptor cluster: a computational study |
Q34253693 | Breast cancer patients' clinical outcome measures are associated with Src kinase family member expression. |
Q33966470 | C-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics |
Q60960537 | Combining a QSAR Approach and Structural Analysis to Derive an SAR Map of Lyn Kinase Inhibition |
Q35043382 | Computational study of the "DFG-flip" conformational transition in c-Abl and c-Src tyrosine kinases |
Q30490298 | Conformational rearrangements upon Syk auto-phosphorylation |
Q37416259 | Conformational snapshots of Tec kinases during signaling |
Q27664248 | Crystal Structure of the Src Family Kinase Hck SH3-SH2 Linker Regulatory Region Supports an SH3-dominant Activation Mechanism |
Q36002820 | Cyclic AMP-induced conformational changes in mycobacterial protein acetyltransferases |
Q94591571 | Depletion of Csk preferentially reduces the protein level of LynA in a Cbl-dependent manner in cancer cells |
Q92074645 | Discovery of Non-peptide Small Molecule Allosteric Modulators of the Src-family Kinase, Hck |
Q35042795 | Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef function using a yeast-based phenotypic screen |
Q41957673 | Dopamine promotes NMDA receptor hypofunction in the retina through D1 receptor-mediated Csk activation, Src inhibition and decrease of GluN2B phosphorylation. |
Q27728152 | Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity |
Q30009032 | Dynamics of the Tec-family tyrosine kinase SH3 domains |
Q30155944 | Effect of the SH3-SH2 domain linker sequence on the structure of Hck kinase |
Q38265286 | Endocytosis and the Src family of non-receptor tyrosine kinases |
Q30009947 | Enhanced SH3/linker interaction overcomes Abl kinase activation by gatekeeper and myristic acid binding pocket mutations and increases sensitivity to small molecule inhibitors |
Q35487552 | Ethanol-induced increase in Fyn kinase activity in the dorsomedial striatum is associated with subcellular redistribution of protein tyrosine phosphatase α |
Q36186331 | Expression and prognostic significance of Src family members in renal clear cell carcinoma |
Q35250443 | Extracellular ATP stimulates epithelial cell motility through Pyk2-mediated activation of the EGF receptor |
Q28546849 | Fluorescence Polarization Screening Assays for Small Molecule Allosteric Modulators of ABL Kinase Function |
Q36139815 | Fyn Activation of mTORC1 Stimulates the IRE1α-JNK Pathway, Leading to Cell Death |
Q30010155 | HIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, Hck |
Q30157107 | Herpes simplex virus requires VP11/12 to induce phosphorylation of the activation loop tyrosine (Y394) of the Src family kinase Lck in T lymphocytes |
Q38773108 | Histoplasma capsulatum-Induced Cytokine Secretion in Lung Epithelial Cells Is Dependent on Host Integrins, Src-Family Kinase Activation, and Membrane Raft Recruitment |
Q30009956 | Individual Src-family tyrosine kinases direct the degradation or protection of the clock protein Timeless via differential ubiquitylation |
Q28308188 | Inhibition of striatal-enriched tyrosine phosphatase 61 in the dorsomedial striatum is sufficient to increased ethanol consumption |
Q30010278 | Interaction between the SH3 domain of Src family kinases and the proline-rich motif of HTLV-1 p13: a novel mechanism underlying delivery of Src family kinases to mitochondria |
Q27653621 | Intertwined dimeric structure for the SH3 domain of the c-Src tyrosine kinase induced by polyethylene glycol binding |
Q42324840 | Involvement of Src in the Adaptation of Cancer Cells under Microenvironmental Stresses |
Q30010192 | Isolation of monobodies that bind specifically to the SH3 domain of the Fyn tyrosine protein kinase |
Q30009548 | Locking the active conformation of c-Src kinase through the phosphorylation of the activation loop |
Q24310120 | Loops govern SH2 domain specificity by controlling access to binding pockets |
Q39984274 | Lyn tyrosine kinase regulates androgen receptor expression and activity in castrate-resistant prostate cancer |
Q43260808 | Lyn-mediated mitochondrial tyrosine phosphorylation is required to preserve mitochondrial integrity in early liver regeneration |
Q41900237 | MBNL142 and MBNL143 gene isoforms, overexpressed in DM1-patient muscle, encode for nuclear proteins interacting with Src family kinases |
Q30157355 | Mapping the conformational transition in Src activation by cumulating the information from multiple molecular dynamics trajectories |
Q27692567 | Mechanisms of drug resistance in kinases |
Q89855395 | Mitochondrial ClpX activates an essential biosynthetic enzyme through partial unfolding |
Q45332101 | Molecular underpinnings of neurodegenerative disorders: striatal-enriched protein tyrosine phosphatase signaling and synaptic plasticity |
Q34185928 | Nef alleles from all major HIV-1 clades activate Src-family kinases and enhance HIV-1 replication in an inhibitor-sensitive manner |
Q28536541 | Norisoboldine suppresses VEGF-induced endothelial cell migration via the cAMP-PKA-NF-κB/Notch1 pathway |
Q35960176 | Nuclear expression of Lyn, a Src family kinase member, is associated with poor prognosis in renal cancer patients |
Q35113711 | On the solution conformation and dynamics of the HIV-1 viral infectivity factor |
Q30009855 | Partial cooperative unfolding in proteins as observed by hydrogen exchange mass spectrometry |
Q34557817 | Permeation through phospholipid bilayers, skin-cell penetration, plasma stability, and CD spectra of α- and β-oligoproline derivatives |
Q34528472 | Phosphorylation of Trask by Src kinases inhibits integrin clustering and functions in exclusion with focal adhesion signaling |
Q33631172 | Protein myristoylation in health and disease |
Q30555799 | Pseudomonas aeruginosa interacts with epithelial cells rapidly forming aggregates that are internalized by a Lyn-dependent mechanism. |
Q41931642 | Purification, crystallization and preliminary X-ray diffraction analysis of the Fyn SH2 domain and its complex with a phosphotyrosine peptide |
Q92752675 | Rapid Characterization of Chemical Components in Edible Mushroom Sparassis crispa by UPLC-Orbitrap MS Analysis and Potential Inhibitory Effects on Allergic Rhinitis |
Q30009300 | SH2-catalytic domain linker heterogeneity influences allosteric coupling across the SFK family. |
Q26744839 | Selective Sensing of Tyrosine Phosphorylation in Peptides Using Terbium(III) Complexes |
Q30493800 | Signaling components of redox active endosomes: the redoxosomes. |
Q27013915 | Small molecule inhibitors of the HIV-1 virulence factor, Nef |
Q27678635 | Small-Molecule Inhibitors of the c-Fes Protein-Tyrosine Kinase |
Q47365767 | Src family kinases (SFKs) and cell polarity in the testis |
Q30009410 | Src kinases regulate de novo actin polymerization during exocytosis in neuroendocrine chromaffin cells |
Q34475481 | Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathway |
Q39719314 | Structural insights into the intertwined dimer of fyn SH2 |
Q36635994 | Structure and dynamic regulation of Abl kinases |
Q33674682 | TOM1L is involved in a novel signaling pathway important for the IL-2 production in Jurkat T cells stimulated by CD3/CD28 co-ligation |
Q35956532 | TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia. |
Q34004470 | Targeted therapies of the LKB1/AMPK pathway for the treatment of insulin resistance |
Q55133068 | Targeting the intracellular signaling "STOP" and "GO" pathways for the treatment of alcohol use disorders. |
Q91698499 | The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein |
Q41591726 | The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation |
Q51766789 | The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects. |
Q34081828 | The PDZ-ligand and Src-homology type 3 domains of epidemic avian influenza virus NS1 protein modulate human Src kinase activity during viral infection. |
Q35156502 | The SH2 domain is crucial for function of Fyn in neuronal migration and cortical lamination |
Q52641604 | The SRC-family tyrosine kinase HCK shapes the landscape of SKAP2 interactome. |
Q28395237 | The blood-testis barrier and its implications for male contraception |
Q30157130 | The formin-homology protein SmDia interacts with the Src kinase SmTK and the GTPase SmRho1 in the gonads of Schistosoma mansoni. |
Q41783109 | The interrelationships between Src, Cav-1 and RhoGD12 in transitional cell carcinoma of the bladder. |
Q26853018 | The molecular rationale of Src inhibition in colorectal carcinomas |
Q30383179 | Theoretical studies of the role of C-terminal cysteines in the process of S-nitrosylation of human Src kinases. |
Q28551159 | Towards a Molecular Understanding of the Link between Imatinib Resistance and Kinase Conformational Dynamics |
Q35973301 | Tubedown regulation of retinal endothelial permeability signaling pathways |
Q37419959 | c-Yes tyrosine kinase is a potent suppressor of ES cell differentiation and antagonizes the actions of its closest phylogenetic relative, c-Src |